1.Metabolism of C(14)-glycine by Clonorchis sinensis.
Soo Hyun SEONG ; Byong Seol SEO
The Korean Journal of Parasitology 1966;4(2):14-22
Radioactive C(14)-glycine was given to Clonorchis sinensis in Tyrode medium in order to trace the metabolic fate of the labeled carbon. The labeled carbon from glycine enters into every major fraction of Clonorchis sinensis and is highest in the fraction of protein and nucleic acid. Significant amount of C(14)-glycine is incorporated into respiratory carbon dioxide. Relatively high percentage of C(14)-glycine in medium is converted to amino acid fraction and lipid fraction of the worm. In general, glycine is continuously being utilized in the synthesis of proteins and for energy production despite the uptake rate of glycine decreased gradually as incubation proceeds.
parasitology-helminth-trematoda
;
Clonorchis sinensis
;
metabolism
;
biochemistry
;
glycine
;
amino acid
;
nucleic acid
;
protein
;
lipid
;
Tyrode medium
2.A Comparison of Biomechanical Characteristics and Morphologise between Operative and Nonoperative Treatments fo Tenotomized Rabbit Achilles Tendon over Lapse of Time
The Journal of the Korean Orthopaedic Association 1995;30(2):192-202
The treatment of Achilles tendon rupture is controversial between surgical repair and conservative cast treatment. This study was attempted to compare the biomechanical and morphological results between operative and nonoperative treatments of experimentally tenotomized rabbit Achilles tendon with the lapse of time. A total of 72 adult rabbits were used. After tenotomizing the Achilles tendons, the subjects were divided into 3 groups according to the time of the initiation of the treatment and each group was subdivided into 2 further subgroups according to the method of treatment; immediate operation and nonoperation, 1 week delayed operation and nonoperation, and 2 weeks delayed operation and nonoperation subgroups. Ten animals from each subgroup were sacrificed after four weeks of cast immobilization and the Achilles tendons were prepared for the gross, biomechanical and histological examinations. At the same time, two animals from each subgroup were examined by Microfil perfusion for microvascular changes in the healed tendons. On biomechanical examination, maximal loads were decreased with the lapse of time in each treatment method, and there were statistical significances between the immediate and 2 weeks delayed operation subgroups, 1 week and 2 weeks delayed operation subgroups, and immediate and 2 weeks delayed nonoperation subgroups. A maximal loads were higher in the operative treatment of each group but there was no statistical significances between operative and nonoperative treatment of each group. The results of absorption energy and stiffness were similar to those of maximal load. In conclusion, these results suggest that a rupture of the Achilles tendon should be treated as early as possible preferably within 1 week, in order to achieve a high tensile strength irrespective of the treatment method. In terms of rerupture, nonoperative treatment is comparable with surgical treatment if a rupture of Achilles tendon is managed within 2 weeks of injury.
Absorption
;
Achilles Tendon
;
Adult
;
Animals
;
Humans
;
Immobilization
;
Methods
;
Perfusion
;
Rabbits
;
Rupture
;
Silicone Elastomers
;
Tendons
;
Tensile Strength
3.Changes of kyphotic angle in children and adults after anterior intervertebral fusion in spinal tuberculosis.
Nam Hyun KIM ; Soo Bong HAHN ; Seong Soo KIM
The Journal of the Korean Orthopaedic Association 1991;26(5):1514-1524
No abstract available.
Adult*
;
Child*
;
Humans
;
Tuberculosis, Spinal*
4.The Mini-perc Technique for Treatment of Renal Calculi.
Il Mo KANG ; Hwan Hyun PARK ; Seong Soo JEON
Korean Journal of Urology 2000;41(11):1335-1341
No abstract available.
Kidney Calculi*
5.Epidermal Glycogen in the Diseases Showing Epidermal Hyperplasia.
In Seong JANG ; Jong Myung HYUN ; Soo Nam KIM
Korean Journal of Dermatology 1984;22(4):387-393
In order to assess the epidermal glycogen in the epidermal hyperplastic disease, PAS(Periodic Acid Schiff) stain with or without diastase is used. Epidermal PAS positive reaction is significantly increased in psoriasis (90. 0%), verruca vulgaris (100%) and lichen simplex chronicus (100%) than control group (12, 5%) Epidermal PAS positive reaction is relatively increased in prurigo nodularis(66. 7 %) and chronic contact dermatitis (75%) Strong PAS positive reaction is noticed in 3 of 5 cases (60%) with verruca vulgaris, but none of 22 cases with psoriasis. It is suggested that epidermal glycogen epidermal hyperplasia and that the more glycogen accumulated. than control group (12. 5%) in 3 of 5 cases (60%) with verruca vulaccumulation is accompanied with the hyperplastic the epidermis is, the more glycogen accumulated.
Amylases
;
Dermatitis, Contact
;
Epidermis
;
Glycogen*
;
Hyperplasia*
;
Neurodermatitis
;
Prurigo
;
Psoriasis
;
Warts
6.Transradial Interventions in Coronary Artery Disease: Comparison with Transfemoral Interventions.
Moo Hyun KIM ; Kwang Soo CHA ; Jong Seong KIM
Korean Circulation Journal 1998;28(12):1941-1952
BACKGROUND: Transradial coronary intervention was introduced recently. It has less bleeding and vascular complications and advantage of early ambulation. METHODS: We compared 142 transradial coronary interventions (101 stents, 56 balloon angioplasty and 18 rotablation) with 120 transfemoral interventions in 230 patients from January to August 1998. RESULTS: Overall success rate was not different between two approaches (92% vs 89%), but smaller sized sheath and less amount of contrast agent were required in transradial interventions compared to transfemoral interventions. Conventional guiding catheters which are used in transfemoral approach were used in most cases (94%) of transradial interventions. Judkins left 3.5 (in stead of JL4.0 in femoral approach) and Judkins right 4.0 were the most frequently used guiding catheters in transradial approach. Stent implantation was successfully done in 99 out of 101 lesions (98%) in transradial intervention and 76 out of 78 lesions (97%) in transfemoral intervention. Rotational atherectomy and primary balloon angioplasty or stenting were done successfully in 10 - 20% of the patients in both groups. All procedures were done successfully without any major procedure-related complications (myocardial infarction, death, bypass surgery) or major vascular complications in both groups. During the clinical follow-up of transradial group, punctured arteries showed 10% incidence of radial artery pulse weakness with 3% of pulse loss. CONCLUSION: Transradial approach is useful another feasible route for coronary interventions. The feasibility of primary balloon angioplasty or stenting and rotational atherectomy by transradial approach should be evaluated in the future.
Angioplasty, Balloon
;
Arteries
;
Atherectomy, Coronary
;
Catheters
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Early Ambulation
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Incidence
;
Infarction
;
Radial Artery
;
Stents
7.The Reliability and Safety of Selective Carotid Angiography from the Right Transradial Approach.
Kwang Soo CHA ; Moo Hyun KIM ; Jong Seong KIM
Korean Circulation Journal 2000;30(4):424-432
BACKGROUND: Carotid artery stenosis is not infrequently associated with coronary artery disease. However, the technique performing selective carotid angiography is not established during right transradial coronary angiography. We investigated the reliability and safety of selective carotid angiography from the right transradial approach. MATERIALS AND METHODS: Following right transradial coronary angiography, selective carotid angio-graphy was performed using a 5 Fr Simmons-2 catheter in 103 patients (59+/-8 years [range, 18-80], 78 males). Ninety five (92%) patients had significant coronary artery disease. Subclavian and innominate arteries were moderately tortuous in 25 (24%) patients and aortic arch was elongated, more vertically oriented in 20 (19%). After forming a loop in ascending (n=65, 63%) or descending (n=38, 37%) aorta, the catheter was withdrawn and rotated counterclockwise to engage its tip in left carotid artery and innominate artery subsequently. After the catheter tip was adjusted at each ostia of carotid arteries, contrast material was delivered. In 63 (61%) patients, the procedures were performed on outpatient basis. RESULTS: Bilateral selective carotid angiography was successfully performed in 101 (98%) patients. In two patients with severely tortuous subclavian artery, the catheter was not engaged selectively in left carotid artery. The image quality of the angiograms performed by manual injection was determined satisfactory. Significant carotid stenosis was found in 17 (17%) patients. There were no complications, including thromboembolism and arterial dissection. CONCLUSION: Selective carotid angiography can be performed reliably and safely using a 5 Fr Simmons catheter from the right transradial approach. This technique is useful for evaluation of isolated or associated carotid artery stenosis from the right transradial approach.
Angiography*
;
Aorta
;
Aorta, Thoracic
;
Brachiocephalic Trunk
;
Carotid Arteries
;
Carotid Stenosis
;
Catheters
;
Coronary Angiography
;
Coronary Artery Disease
;
Humans
;
Outpatients
;
Radial Artery
;
Subclavian Artery
;
Thromboembolism
8.The Significance of Liquid Crystal Thermography in Patents with Low Back Pain
Nam Hyun KIM ; Chang Dong HAN ; Seong Soo KIM
The Journal of the Korean Orthopaedic Association 1990;25(2):510-518
Liquid crystal thermography is a new diagnostic imaging method detecting the temperature change by the physiologic disturbance as compared with the radilogic method detecting the anatomical distortion. We have used liquid crystal thermography in 54 patients with complaining low back pain during the period form 2nd. March 1989 to 30th. April 1989. Of these 54 patients, 35 had myelography and C-T scan, 23 had EMG, and 13 were operated upon. 1. There were 35 clinically positive patients on whom concomitant myelography and C-T scan was performed; 32 patients(91%) had a positive myelography and C-T scan, and 30 patients (86%) had a positive thermography. Of these 35 patients, 23 had EMG concomitantly; 17 patients(74%) had a positive EMG and 18 patients(78%) had a positive thermography. 2. Liquid crystal thermography correlated with myelography and C-T scan in 31 patients(89%), EMG in 18 patients(78%). 3. Concomitant thermography, myelography and C-T scan, and surgery were performed on 13 patients among them EMG was added on 5 patients; Myelography and C-T scan had 100% accuracy, thermography had 92% accuracy, and EMG had 80 % accuracy. 4. Liquid crystal thermography is non-invasive method, dose not involve the use of ionizing radiation, and correlates well with clinical and surgical findings and other diagnostic methods, and costs relatively low. So, liquid crystal thermography is useful and reliable diagnostic method in patients with low back pain.
Diagnostic Imaging
;
Humans
;
Liquid Crystals
;
Low Back Pain
;
Methods
;
Myelography
;
Radiation, Ionizing
;
Thermography
9.A Comparative Study of Arrhythmogenic Doses of Epinephrine during Sevoflurane or Halothane Anesthesia in the Dogs.
Byeong Seong KANG ; Seok Hoon YOON ; Tae Seong KIM ; Hyun Soo KIM ; Kwang Min KIM
Korean Journal of Anesthesiology 1997;33(1):1-5
BACKGROUND: Epinephrine used in surgery to provide hemostasis may elicit ventricular arrhythmias. A desirable anesthetic would not sensitize the myocardium to exogenously administered epinephrine. So the effect of sevoflurane, which was introduced to clinical anesthesia recently, on cardiac arrhythmias induced by the infusion of epinephrine was compared with those of halothane which was already known to epinephrine-induced arrhythmia in the 14 mongrel dogs. METHODS: The authors compared the arrhythmogenicity (three or more premature ventricular contractions, PVCs)of intravenously administered epinephrine in 14 mongrel dogs who were randomly assigned to receive sevoflurane (1.7 vol%) or halothane (0.75 vol%) anesthesia equipotently. The arrhythmogenic doses of epinephrine determined in this comparative study were expressed by both infusion rates of epinephrine during sevoflurane and halothane anesthesia. RESULTS: The mean values of the arrythmogenic infusion rates of epinephrine were 27.1 7.6 g/kg for sevoflurane and 2.7 0.8 g/kg for halothane. CONCLUSIONS: We concluded that the arrythmogenic doses of epinephrine during sevoflurane were significantly higher than those during halothane anesthesia.
Anesthesia*
;
Animals
;
Arrhythmias, Cardiac
;
Dogs*
;
Epinephrine*
;
Halothane*
;
Hemostasis
;
Myocardium
;
Ventricular Premature Complexes
10.The Usefulness of Endo-rectal Coil MRI in the Staging of Clinically Localized Prostate Cancer.
Eun Tak KIM ; Seong Soo JEON ; Soo Eung CHAI ; Bo Hyun KIM ; Han Yong CHOI
Korean Journal of Urology 2001;42(5):500-505
PURPOSE: We evaluated the ability of endo-rectal coil MRI (ER-MRI) to predict the local pathological stage of prostate cancer prior to radical prostatectomy and compared the results with those of transrectal ultrasonography (TRUS). MATERIALS AND METHODS: ER-MRI using high field magnets (1.5 Tesla) were performed in 22 patients (mean age 62.8 years, range 51-73) with clinically localized prostate cancer before radical prostatectomy. Of the 22 patients, 17 patients were also assessed by TRUS. The results of the imaging techniques were compared with the post-operative histopathological findings. As one patient with pelvic lymph node metastasis, which was detected on frozen-section examination during surgery, was spared radical prostatectomy, the final evaluation included 21 patients. RESULTS: DSeven of the 21 patients (33%) were found to have extraprostatic extension (EPE), and 5 had seminal vesicle invasion (SVI). The sensitivity and specificity for diagnosing EPE using ER-MRI were 62.5% and 84.6%, respectively, and 16.7% and 100% with TRUS. The sensitivity and specificity for diagnosing SVI were 80.0% and 93.8%, respectively with ER-MRI, and 0% and 92.3% with TRUS. The accuracy of predicting SVI was 90.5% with ER-MRI compared to 70.6% with TRUS. CONCLUSIONS: ER-MRI was significantly better than TRUS for determining the local extent of prostatic cancer and for prediction of SVI in the preoperative staging of clinically localized prostate cancer.
Humans
;
Lymph Nodes
;
Magnetic Resonance Imaging*
;
Neoplasm Metastasis
;
Prostate*
;
Prostatectomy
;
Prostatic Neoplasms*
;
Seminal Vesicles
;
Sensitivity and Specificity
;
Ultrasonography