1.Neuropsychological Assessment for Verbal Function.
Min Sup SHIN ; Hyun Joo LEE ; Jun Soo KWON
Journal of the Korean Society of Biological Psychiatry 1997;4(1):12-18
In this article neuroanatomical and verbal developmental process were introduced, followed that disorders and assessment of language function were reviewed. Finally, the causes and assessment of developmental dyslexia as a childhood disorder related to verbal function were reviewed.
Dyslexia
;
Neuropsychology
2.A Clinical Study of the Tibial Plafond Fractures
Byung Hyun JUNG ; Chil Soo KWON ; Kwang Yoon SEO
The Journal of the Korean Orthopaedic Association 1988;23(1):49-56
The tibial plafond fractures result from an axial compression snd rotational forces causing variable degrees of metaphyseal disruption, articular damage, and malleolar displscement. It is relatively uncommon but a most difficult fracture to manage. It has been treated in a number of manners, but the best results have been occurred when stable internal fixation is accomplished using plates and screws. Basic steps in reconstruction are restoration of anatomic length of the fibula with plate fixation, reconstruction of the tibial articular surface, cancellous bone grafting of the metaphyseal defect and buttress plating of the distal tibia. The suthor analysed the 20 cases of the tibial plafond frsctures in 17 patients, which were trested at the Department of Orthopedic Surgery, Paik Hospital, Inje Medical College from Jsnuary 1983 to March 1987. The longest durstion of followup was 2 years and 4 months and shortest one was 6 months, and the aversge was one year. The results were as follows : 1. Among the 17 patients, male were 16 and female was one. 2. The major causes of injury were a fall from a height. 3. The most frequent type of fracture was type C by Ruedi and Allgower classification. 4. Regardless of the method of trestment the type A and B were in good and fair result, but the type C were fair in 4 cases and poor in 8 cases. There were 7 cases of snkle fusion in poor group. 5. It is important to remind the basic steps in reconstruction and applied in sn individual csse especially in type C. If anatomic reconstruction of the joint surface can be restored and stable fixation achieved, esrly motion of the ankle joint is made possible. This early motion reduces stiffness of the ankle and win yeild the most sstisfying result. But the anatomic reduction of ank1 joint is difficult to be obtained in each case especially in type C and may consider an ankle fusion.
Ankle
;
Ankle Joint
;
Bone Transplantation
;
Classification
;
Clinical Study
;
Female
;
Fibula
;
Follow-Up Studies
;
Humans
;
Joints
;
Male
;
Methods
;
Orthopedics
;
Tibia
3.Two Cases of High Flow Priapism.
Dong Soo RYU ; Chang Ho CHONG ; Jun O KWON ; Hyun Soo KIM ; Tae Hee OH
Korean Journal of Urology 2000;41(1):190-193
No abstract available.
Priapism*
4.Two Cases of High Flow Priapism.
Dong Soo RYU ; Chang Ho CHONG ; Jun O KWON ; Hyun Soo KIM ; Tae Hee OH
Korean Journal of Urology 2000;41(1):190-193
No abstract available.
Priapism*
5.Biologic Arthroplasty of the Elbow Joint
Chil Soo KWON ; Byung Hyun JUNG ; Yong Uck KIM ; Dong Soo KIM
The Journal of the Korean Orthopaedic Association 1995;30(4):1050-1057
The stiffness of the elbow joint is caused by trauma, infection, and ect. The conventional arthrop lasty and arthrodesis of this joint has been used but the indication is very limited because of unsati sfactory result. The Oganesyan external fixator, which was invented by Mstislav V. Volkov and Oganes V. Oganesyan in 1971, generally employes tne hinged-distraction apparatus to treat joint stiffness and flexion contracture. According to them, regeneration of both cartilage and underlying subchondral bony tissue is possible. These authors consider the main factor for regeneration of the cartilage af a destroyed joint surface to be early restitution of joint functions including unloaded motion and elimination of increased friction between the joint surfaces. From Jan. 1992 to Jan. 1994, We have experienced the 6 cases of stiff elbow who had been undergone biologic arthroplasty. The results were as follows; The gain of the average range of motion of the joint at final follow-up was 50.5°. The complications were mild pain in 2 cases, mild instability on exertion in 2 cases, recurrence of contracture in two cases and ulnar nerve irritation in one case. The complications affected no significant long term results except recurrence.
Arthrodesis
;
Arthroplasty
;
Cartilage
;
Contracture
;
Elbow Joint
;
Elbow
;
External Fixators
;
Follow-Up Studies
;
Friction
;
Joints
;
Range of Motion, Articular
;
Recurrence
;
Regeneration
;
Ulnar Nerve
6.Effect of Medicult and Human Tubal Fluid Culture Media and Cumulus Cell Coculture on Early Mouse Embryo Development in vitro.
Young Sook KWON ; Hyun Jeong PARK ; Hyun Soo LEE ; Yu Il LEE
Korean Journal of Obstetrics and Gynecology 1999;42(11):2549-2557
Objectives: This study was to evaluate whether Ham's F-10 used in assisted reproductive technology (ART) could be replaced with newly-introduced Medicult or Human Tubal Fluid (HTF) media, and the rate of embryo development could be enhanced by cumulus cell coculture. METHODS: Ham's F-10, Medicult, and HTF media supplemented with 0.4% bovine serum albumin (BSA) were used. Two-cell embryos were obtained from oviducts of mated F1 hybrid female mice superovulated by pregnant mare serum gonadotropin (PMSG) and human chorionic gonadotropin (hCG). Cumulus cells for coculture were obtained from oviducts of ICR female mice superovulated by PMSG and hCG. Two-cell embryos were cultured in Ham's F-10, Medicult, and HTF media respectively to observe and compare the rate of embryo development. In addition, two-cell embryos were cultured in these three media for 24, 48, 72, 96 hrs with or without cumulus cell, and rates of embryo development were investigated and compared. RESULTS: As for the rate of embryo development to hatched blastocyst after 96 hrs culture, HTF (87.5%) and Ham's F-10 (85%) were significantly higher than Medicult (70.5%). The beneficial effect of embryo development by cumulus cell coculture on two-cell mouse embryo among these three media was enhanced significantly in Medicult (control 88.5% versus coculture 98.5%) by 24 hrs, and was not enhanced statistical significantly but slightly elevated in Ham's F-10 (86.5% versus 95.5%) and HTF (91.3% versus 96.9%) by 48 hrs, but rates of embryo development were similar between control and coculture group in all three media by 96 hrs. Significant differences were not shown in three media, but HTF showed generally high tendency of the enhancing effect of embryo development and the beneficial effect of embryo development by coculture. CONCLUSIONS: As a result of culturing two-cell embryos in three media for 96 hrs, generally HTF and Ham's F-10 showed higher rate of embryo development than Medicult. As for the beneficial effect of coculture, Medicult only showed early transient significant improvement of embryo development. Considering that coculture effect of good quality media may be not so great, Ham's F-10 and HTF are more stable media than Medicult. Accordingly, HTF may be considered to be a medium to replace with Ham's F-10, however, the present study suggest that Medicult or HTF is not able to replace with Ham's F-10 in ART.
Animals
;
Blastocyst
;
Chorionic Gonadotropin
;
Coculture Techniques*
;
Culture Media*
;
Cumulus Cells*
;
Embryonic Development*
;
Embryonic Structures*
;
Female
;
Gonadotropins
;
Humans*
;
Mice*
;
Oviducts
;
Pregnancy
;
Reproductive Techniques, Assisted
;
Serum Albumin, Bovine
7.The effects of oophorectomy and hysterectomy on rat spine and tibia.
Soo Hyun CHO ; Jung Kwon CUNG ; Kyung Tai KIM ; Sam Hyun CHO ; Jai Auk LEE
Korean Journal of Obstetrics and Gynecology 1993;36(11):3784-3791
No abstract available.
Animals
;
Female
;
Hysterectomy*
;
Ovariectomy*
;
Rats*
;
Spine*
;
Tibia*
8.Clinical Correlates of Subeortical Hyperintensities on Magnetic Resonance Imaging in Patients with Bipolar Disorder: Preliminary Study.
Dae Hyun YOON ; Jun Soo KWON ; Moon Hee HAN ; Kee Hyun CHANG
Journal of the Korean Society of Biological Psychiatry 1997;4(1):60-66
OBJECT: Accumulating evidence suggests a greater number of subcortical hyperintensities in the brain with bipolar disorder. We studied the Clinical correlates of subcortical hyperintensities on magnetic resonance imaging in patients with Bipolar Disorder. METHODS: Magnetic resonance images of the brain were obtained for 32 patients with bipolar disorder. The presence and location of hyperintensities were assessed. We compared clinical variables between with subcortical hyperintensities and patients without them. RESULTS: Seven Patients(21.8%) had subcortical hyperintensities, but among 8 patients who were or older, 5 patients(625) had them, Age and age of onset of patients with subcotical hyperintensities were significantly older than patients without them. Psychotic symptoms were more frequent in patients with hyperintensities. Patients without hyperintesities had more familial loading. CONCLUSION: Given the limitations of the study, our results should be seen as preliminary. This study, however, provides preliminary evidence supporting the notion that the onset, clinical feature and course of some bipolar disorders of late onset may be determined by underlying subcortical abnormalities, with such abnormalities being the consequence of factors related to aging or neurodegeneration(such as impaired cerebral circulation) rather than genetic factors which predispose to early-onset bipolar disorders.
Age of Onset
;
Aging
;
Bipolar Disorder*
;
Brain
;
Humans
;
Magnetic Resonance Imaging*
9.Evaluation of Lipoprotein(a) as a Risk Factor for Coronary Artery Disease.
Hyun Young PARK ; Han Soo KIM ; Hyuck Moon KWON ; Yang Soo JANG ; Seung Yun CHO ; Hyun Seung KIM
Korean Circulation Journal 1993;23(4):542-548
Lipoprotein(a)[Lp(a)] is a LDL-like particle with a glycoprotein called apo(a) attached to its apoB through disulfide bond. Many case-control studies support the opinion that plasma Lp(a) levels were associated with coronary artery disease. This study was conducted to assess the relationship between plasma Lp(a) level and coronary artery disease in Korean population. Serum levels of Lp(a), in addition to other lipids and known clinical risk factors for coronary artery disease were determined in 92 subjects undergoing coronary angiography. Among them 30 patients had no obstruction in the coronary artery(cath-control group), while the others revealed the presence of coronary artery stenosis more than 50%(CAD group). The Lp(a) levels of the CAD group were significantly higher the those of cath-control group(31.8+/-25.0mg/dl vs 14.6+/-11.9mg/dl, p<0.005). Other lipids except triglycerides(166.9+/-70.5mg/dl vs 116.2+/-56.1mg/dl, p<0.005) were not significantly different between two groups. The patients with significant coronary artery disease of two or more vessels were found to have higher Lp(a) levels than those of one vessel disease. Lp(a) levels had no relations with other lipids, diabetes, smoking, hypertension and age. Stepwise discriminant analysis revealed that Lp(a) was the best discriminator among risk factors for coronary artery disease. These results suggested that Lp(a) level was a significant independent risk factor for coronary artery disease.
Apolipoproteins B
;
Case-Control Studies
;
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Stenosis
;
Coronary Vessels*
;
Glycoproteins
;
Humans
;
Hypertension
;
Lipoprotein(a)*
;
Plasma
;
Risk Factors*
;
Smoke
;
Smoking
10.Comparative Study of Clinical Characteristics according to Therapeutic Efficacy and Drug Survival of Cyclosporine or Methotrexate in Psoriasis Vulgaris
Hyun Soo LEE ; Soo Hyun KWON ; Eun So LEE
Annals of Dermatology 2019;31(4):469-472
No abstract available.
Cyclosporine
;
Methotrexate
;
Psoriasis