No abstract available.
Fever* ; Flank Pain*

No abstract available.
Fever* ; Flank Pain*

Testicular biopsy is an important tool in the diagnosis and management of male infertility. Other types of analysis such as plasma hormonal assay, chromosomal studies and biochemical determination of ejaculate components have also a role in characterizing male infertility. There were 53 infertile males who received testicular biopsy in our department during the period from January, 1972 to June, 1982. A clinical investigation was undertaken in aspect of testicular size, past history, testicular biopsy findings and plasma hormonal level. The following results were obtained: 1. On semen analysis, oligospermia was found in 5 cases, azoospermia in 48 cases and the most common age group was 4th decade. 2. The biopsy findings of 41 cases with normal size testis were normal in 20 cases. hypospermatogenesis in 8 cases, peritubular fibrosis with reduced spermatogenesis in 4 cases. maturation arrest in 4 cases germinal aplasia in 4 cases, hyalinized seminiferous tubule with Leydig cell hyperplasia in 1 case. 3. The biopsy findings of 12 cases with small size testis were hypospermatogenesis in 3 cases. hyalinized seminiferous tubule with Leydig cell hyperplasia in 6 cases, peritubular fibrosis with reduced spermatogenesis in 1 case, maturation arrest in 1 case, germinal aplasia in 1 case. 4. There were 20 cases which had induration on epididymis or vas deferens. On their past history, gonorrheal urethritis in 7 cases, nonspecific epididymitis in 4 cases, tuberculous epididymitis in 3 cases, undetermined cause in 6 cases were observed. 5. The biopsy findings of 20 cases with indurated epididymis or vas deferens were normal in 13 cases, peritubularfibrosis with reduced spermatogenesis in 4 cases, hypospermatogenesis in 3 cases. 6. The plasma hormonal assay (FSH, LH, Testosterone) was performed in 8 cases.
Azoospermia ; Biopsy* ; Diagnosis ; Epididymis ; Epididymitis ; Fibrosis ; Humans ; Hyalin ; Hyperplasia ; Infertility, Male ; Male ; Oligospermia ; Plasma ; Semen Analysis ; Seminiferous Tubules ; Spermatogenesis ; Testis ; Urethritis ; Vas Deferens

Dermoid cyst is a benign cystic teratoma consisting of 3 germ cell origin tissues with predominant ectodermal origin and most commonly found in the ovary but rare in the scrotum. We reported two cases of intrascrotal dermoid cysts developed in 7 months and 3 years old boys which were confirmed hiatologically. In one case, the cyst developed from the testis and in another from the paratesticular tissue.
Child, Preschool ; Dermoid Cyst* ; Ectoderm ; Female ; Germ Cells ; Humans ; Ovary ; Scrotum ; Teratoma ; Testis

Calcium has been implicated as a primary pathogenetic mediator of cellular injury under conditions of oxygen and substrate deprivation in the kidney aswell as other tissues. It has been proposed that calcium entry from the external medium increases intracellular free calcium to toxic levels there-by converting cellular injury from a potentially reversible to an irreversible state. Cellular calcium homeostasis is a fundamental prerequisite for many coordinate cellular functions. The regulation of cellular Ca++ -metabolism is maintained mainly by Ca++ -ATPase. The purpose of the present study was to determine the effects of ischemia on the subcellular specific activity of Ca++ -ATPase of renal tissues in the rabbits. 1. In both normal cortical and medullary tissues, the specific activities Ca++ -ATPase were higher in mitochondria than in cytosol. 2. In cortical tissue, the specific activities of mitochondrial Ca++ -ATPase were increased with duration of ischemic time under normothermia. But the specific activities were decreased comparing to those of control under hypothermia, and the activities were not different with those of control in Verapamil treated group. 3. The specific activities of Ca++ -ATPase of cortical cytosol were increased as in mitochondria under normothermia. And the activities were similar with those of control in hypothermic and Verapamil treated groups. 4. In medullary tissues, the specific activities of mitochondrial Ca++ -ATPase were increased with duration of ischemic time under normothermia. In Verapamil treated group, the activities were decreased comparing to those of control. And there was no difference of activities between hypothermia and control groups. 5. As in cortical tissues, the specific activities of Ca++ -ATPase of medullary, cytosol were increased in normothermic group. And the activities were similar with those of control in hypothermic and Verapamil treated groups. Above results suggested that calcium contents of mitochondria and cytosol were increased with duration of ischemic time under normothermia. Hypothermia and Verapamil treatment seemed to be beneficial effects in prevention of calcium accumulation in the renal tissues.
Adenosine Triphosphatases* ; Calcium ; Cytosol ; Homeostasis ; Hypothermia ; Ischemia* ; Kidney ; Mitochondria ; Oxygen ; Rabbits* ; Subcellular Fractions* ; Verapamil

No abstract available.
Biopsy* ; Neoplasm Metastasis* ; Prostate* ; Prostatic Neoplasms*

No abstract available.

PURPOSE: We evaluated the ability of endo-rectal coil MRI (ER-MRI) to predict the local pathological stage of prostate cancer prior to radical prostatectomy and compared the results with those of transrectal ultrasonography (TRUS). MATERIALS AND METHODS: ER-MRI using high field magnets (1.5 Tesla) were performed in 22 patients (mean age 62.8 years, range 51-73) with clinically localized prostate cancer before radical prostatectomy. Of the 22 patients, 17 patients were also assessed by TRUS. The results of the imaging techniques were compared with the post-operative histopathological findings. As one patient with pelvic lymph node metastasis, which was detected on frozen-section examination during surgery, was spared radical prostatectomy, the final evaluation included 21 patients. RESULTS: DSeven of the 21 patients (33%) were found to have extraprostatic extension (EPE), and 5 had seminal vesicle invasion (SVI). The sensitivity and specificity for diagnosing EPE using ER-MRI were 62.5% and 84.6%, respectively, and 16.7% and 100% with TRUS. The sensitivity and specificity for diagnosing SVI were 80.0% and 93.8%, respectively with ER-MRI, and 0% and 92.3% with TRUS. The accuracy of predicting SVI was 90.5% with ER-MRI compared to 70.6% with TRUS. CONCLUSIONS: ER-MRI was significantly better than TRUS for determining the local extent of prostatic cancer and for prediction of SVI in the preoperative staging of clinically localized prostate cancer.
Humans ; Lymph Nodes ; Magnetic Resonance Imaging* ; Neoplasm Metastasis ; Prostate* ; Prostatectomy ; Prostatic Neoplasms* ; Seminal Vesicles ; Sensitivity and Specificity ; Ultrasonography

Clinical observation was done on 40 cases of renal cell carcinoma, who have been admitted to the Department of Urology, Kyung Hee University Hospital from January, 1978 to January, 1988. The results were obtained as follows. 1. Among 40 patients, there were 22 men and 18 women, with peak incidence at the sixth decade. 2. Hematuria was the most frequent symptom at the presentation followed by flank pain and abdominal mass. 3. On laboratory examinations, 4 patients had anemia and 2 patients had erythrocytosis. Among 7 patients with hypercalcemia, 2 patients had bone metastasis. 6 patients showed abnormal liver function and liver function became normalized after nephrectomy in 5 of them. 4. Comparing to pathologic stage, accuracy of CT scan in determining of stage was 82.3 %, 5. 3 year-survival rate was 75% in patients with stage I, and 33% in stage II, 40% in stage III. 6. In 14 patients, there were metastasis to lung, lymph node and bone in order of frequency.
Anemia ; Carcinoma, Renal Cell* ; Female ; Flank Pain ; Hematuria ; Humans ; Hypercalcemia ; Incidence ; Liver ; Lung ; Lymph Nodes ; Male ; Neoplasm Metastasis ; Nephrectomy ; Polycythemia ; Tomography, X-Ray Computed ; Urology

Renal and perinephric abscess are uncommon diseases with a multitude of clinical presentations. In past morbidity and mortality were high rate because of delay in diagnosis. Diagnosis and treatment approaches were challenged recently by newer imaging modalities as ultrasonography and CT scanning and by interventional uroradiology. A clinical observation was made in 9 patients with renal abscess and 1O patients with perinephric abscess admitted in the Dept. of Urology, Kyung Hee University Hospital during the period from Jan. 1981 to Jan. 1986. The following results were observed: 1. Among 19 patients, 11 patients were women and their age was ranged from 22 to 68 yrs old with mean of 44.5 yrs. In 12 cases, Lt. kidneys were involved. 2. In 5 patients who had positive urine culture, E. coli was recovered in 3 cases, and klebsiella sp. and staph. epldermidis were recovered in one case, respectively. Blood culture was positive in one case. Among 14 cases performed pus culture, bacteria was recovered in 8 cases: E. coli in 4 cases staph. aureus in 2 cases, and staph. epldermidis and peptococcus in one case, respectively. 3. In 15 cases, diagnosis could be confirmed by ultrasonography, but CT scan was needed in 4 cases to confirm the nature of lesion. The common findings of ultrasonogram were mixed echogenic mass and echolucent mass found in 8 cases and 7 cases, respectively. 4. Among 19 cases, 1O patients underwent open drainage, 5 cases were treated by antibiotics only, and 3 cases were managed successfully by closed drainage.
Abscess* ; Anti-Bacterial Agents ; Bacteria ; Diagnosis ; Drainage ; Female ; Humans ; Kidney ; Klebsiella ; Mortality ; Peptococcus ; Suppuration ; Tomography, X-Ray Computed ; Ultrasonography ; Urology