1.Clinical profile and outcome of idiopathic restrictive cardiomyopathy in children.
Eun Jung BAE ; Eun Jung CHEON ; Yong Soo YUN
Korean Circulation Journal 2001;31(4):427-433
BACKGROUND AND OBJECTIVES: Idiopathic restrictive cardiomyopathy is a very rare and poorly recognized disease in children. This study is performed to describe the clinical course and to define potential predictors of outcome. MATERIAL AND METHOD: We reviewed the medical records and diagnostic studies of 11 consecutive patients during the period from Jan.1991 to Aug. 2000. RESULTS: The age at diagnosis was 1.2-13 years (median 7 years) and the duration of follow up was 3-90 months (median 3.6 years). All except one were symptomatic (dyspnea in ten, chest pain in four). The chest pain was associated with significant ST depression on both resting and exercise ECG, suggesting myocardial ischemia. Two had complete heart block as either initial or terminal event. Cardiac catheterization was done in nine ( mean pulmonary arterial wedge pressure 23+/-6mmHg, systolic pulmonary arterial pressure 47+/-14mmHg, mean right atrial pressure 11+/-9mmHg). Echocardiographic dimensional ratio of left atrium and aorta (LA/Ao) was 2.41+/-0.58. Mitral E/A inflow ratio was 2.72+/-1.42, E wave deceleration time was 93.6+/-44.2ms. During follow up, six died. The 2 year and 5 year cumulative survival rates were 54.5% and 18.8% respectively. The predictor for nonsurvivor were pulmonary venous congestion and LA/Ao >2.5(p<0.05). Verapamil was tried in 6 cases without favorable effect in all. CONCLUSION: Considerable numbers of restrictive cardiomyopathy have myocardial ischemia associated with ST depression and chest pain. The patients with pulmonary venous congestion and severe left atrial enlargement (LA/Ao>2.5) were at risk for death, requiring prompt definitive treatment such as cardiac transplantation.
Aorta
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Arterial Pressure
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Atrial Pressure
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Cardiac Catheterization
;
Cardiac Catheters
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Cardiomyopathy, Restrictive*
;
Chest Pain
;
Child*
;
Deceleration
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Depression
;
Diagnosis
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Echocardiography
;
Electrocardiography
;
Follow-Up Studies
;
Heart Atria
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Heart Block
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Heart Transplantation
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Humans
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Hyperemia
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Medical Records
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Myocardial Ischemia
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Pulmonary Wedge Pressure
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Survival Rate
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Verapamil
2.Two Cases of Erythema Infectiosum.
Korean Journal of Dermatology 2014;52(9):671-672
No abstract available.
Erythema Infectiosum*
3.A clinical study on acute suppurative cholangitis.
Journal of the Korean Surgical Society 1992;42(4):485-492
No abstract available.
Cholangitis*
4.The Korean Journal of Radiology Launches an Online Manuscript Submission and Tracking System for Peer Review.
Jung Eun CHEON ; Kyung Soo LEE
Journal of the Korean Radiological Society 2005;53(3):157-157
No abstract available.
Peer Review*
5.The Correlations between Cardiorespiratory Fitness Levels and Body Mass Index, Metabolic Syndrome Risk Factors, Homeostasis Model Assessment-Insulin Resistance and High Sensitivity C-Reactive Protein in Male High School Students.
Soo Youn KIM ; Eun Sung KIM ; Jung Ho CHO
Korean Journal of Health Promotion 2011;11(4):227-233
BACKGROUND: The purpose of this study was to analyze the relationships between cardiorespiratory fitness and body mass index (BMI), metabolic syndrome risk factors, homeostasis model assessment-insulin resistance (HOMA-IR), and high sensitivity C-reactive protein (hsCRP) in male high school students in Korea. Furthermore, the effects of the cardiorespiratory fitness levels on these four factors were examined. METHODS: The level of cardiorespiratory fitness, BMI, percent body fat, waist circumference (WC), systolic blood pressure, glucose, triglycerides (TG), high-density lipoprotein-cholesterol (HDL-C), HOMA-IR, and hsCRP of 227 male high school students were measured. Analyses of multiple correlation and simple regression were applied. RESULTS: The results showed that the level of cardiorespiratory fitness correlated negatively with BMI, percent body fat, WC, TG, and HDL-C, in addition to HOMA-IR and hsCRP, and strongly influenced BMI, percent body fat, WC, TG, HDL-C, HOMA-IR, and hsCRP. Comparative analysis of our subjects showed that higher cardiorespiratory fitness levels had positive effects on BMI, metabolic syndrome risk factors, HOMA-IR, and hsCRP. CONCLUSIONS: This study found that there are close correlations between cardiorespiratory fitness and BMI, metabolic syndrome risk factors, HOMA-IR, and hsCRP. It also showed that, compared to lower levels of cardiorespiratory fitness, higher levels had beneficial effects on BMI, metabolic syndrome risk factors, diabetes, and cardiovascular disease risk factors.
Adipose Tissue
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Adolescent
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Blood Pressure
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Body Mass Index
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C-Reactive Protein
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Cardiovascular Diseases
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Glucose
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Homeostasis
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Humans
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Insulin
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Korea
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Male
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Physical Fitness
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Risk Factors
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Triglycerides
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Waist Circumference
6.A Case of Spontaneous Discitis in Child.
Eun Jung LEE ; Joon Soo LEE ; Chang Jun COE
Journal of the Korean Child Neurology Society 1998;6(1):133-137
The authors present a case of spontaneous discitis in a 1-year-old female who presented with fever and limping gait. The erythrocyte sediment rate was increased. The roentgenograms revealed normal appearnce, and radioactive bne scan showed increased uptake at the affected level. Discitis should be considered in any child with limping gait or leg pain, refusal to walk, or abdominal pain. Early recognition may avoid unnecessary diagnotic and treatment procedures.
Abdominal Pain
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Child*
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Discitis*
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Disulfiram
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Erythrocytes
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Female
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Fever
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Gait
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Humans
;
Leg
7.Synovial fluid osmolarlity of human knee.
Eun Woo LEE ; Soo Yong KANG ; Jung Hwan SEO
Journal of the Korean Knee Society 1991;3(1):15-18
No abstract available.
Humans*
;
Knee*
;
Synovial Fluid*
8.Ipsilateral Tibial Shaft Fractures and Knee Ligament Injuries
Eun Woo LEE ; Soo Yong KANG ; Jung Hwan SEO
The Journal of the Korean Orthopaedic Association 1990;25(5):1317-1322
Nine patients with ipsilateral tibial shaft fractures and knee ligament injuries were retrospectively reviewed to determine the methods of the diagnosis and the results of the treatment. The incidence of this combined injuries was 5% in one hundred and eighty two tibial shaft fractures. The injuries of posterior cruciate ligament were combined most freqently. Five of nine patients were open fractures. Bone union was obtained in all cases and the mean duration of bone union was 22.5 weeks. Athroscopy and stress X-ray for the cruciate ligament were helpful to diagnose this combined injures. The ligament injuries were surgically managed in eight and conservatively in one. Better results were obtained when this combined injuries were operated early, but four of nine patients were disabled. The results suggest that the examination of the knee is necessary to document ligamentous injuries that occur with tibial shaft fractures.
Diagnosis
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Fractures, Open
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Humans
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Incidence
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Knee
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Ligaments
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Posterior Cruciate Ligament
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Retrospective Studies
9.An Open-Label, Multicentre, Observational, Post-Marketing Study to Monitor the Safety and Effectiveness of Umeclidinium/Vilanterol in Korean Patients
Eun-Yeong CHO ; Jung-Eun CHO ; Eun-Bin LEE ; Seung Soo YOO ; Jung Hyun CHANG
Tuberculosis and Respiratory Diseases 2023;86(1):33-46
Background:
Umeclidinium/vilanterol (UMEC/VI; ANORO ELLIPTA, GSK) is a commonly used dual bronchodilator. This study evaluated the safety and effectiveness of UMEC/VI in Korean patients with chronic obstructive pulmonary disease (COPD) over a 6-year period.
Methods:
This was an open-label, multicentre, observational, post-marketing surveillance study. A total of 3,375 patients were enrolled consecutively in 52 hospitals, by 53 physicians, between July 2014 and July 2020. Patients who were administered UMEC/VI (fixed-dose 62.5 μg/25 μg) at least once and were monitored for safety and effectiveness were included in the analysis. Incidence and severity of adverse events (AEs) reported after administrating at least one dose of UMEC/VI were monitored, including unexpected adverse events (UAEs) and adverse drug reactions (ADRs). Effectiveness of UMEC/VI after 24 weeks of administration was also assessed using physician’s evaluation (effective, ineffectiveo change, worsening, indeterminable) and lung function improvement.
Results:
Of 3,375 patients, 3,086 were included in the safety assessment group (mean age±standard deviation: 69.76±8.80 years; 85.9% male [n=2,652]; 73.1% aged ≥65 years [n=2,255]). The overall incidence of AEs was 28.8% (n=890), of which 2.2% (n=67) were ADRs. Serious AEs and UAEs were reported in 181 (5.9%) and 665 (21.6%) patients, respectively, and two patients (<0.1%) reported unexpected severe ADR. Of the 903/3,086 patients analysed for effectiveness, most (82.8%, n=748) showed overall disease improvement after UMEC/VI treatment.
Conclusion
This study confirmed UMEC/VI administered to Korean patients according to the prescribing information was well-tolerated and can be considered an effective option for COPD treatment.
10.Gastric Choriocarcinoma and Endodermal Sinus Tumor in Collision Tumor.
Eun Kyung KIM ; Eun Kyung HONG ; Kwang Soo LEE ; Jung Dal LEE
Korean Journal of Pathology 1992;26(4):405-410
Both primary choriocarcinoma and endodermal sinus tumor of the stomach are very rare entities. Combination of these two tumors is even rarer, and only a single such case has been reported in English literature. The case had gastric adenocarcinoma in addition to these tumors. We experienced a case of combined, pure choriocarcinoma and endodermal sinus tumor in the stomach of a 74 year-old man. He had no gonadal or any other primary tumor. Huge exophytic tumor was located in the lesser curvature of the body. Two components of the tumor was separated and clearly defined. Human chorionic gonadotropin(HCG) was demonstrated in serum and in tissue sections. Alpha-fetoprotein(alpha-FP) was also demonstrated in serum and in tissue sections. Alpha-fetoprotein(alpha-FP) was also elevated in the serum. Possible tumor origin was speculated.
Humans
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Adenocarcinoma