3.A Study of Topical Corticosteroid Effect on the Rat Skin Mast Cell.
Seok Ho KIM ; Eil Soo LEE ; Chin Yo CHANG
Korean Journal of Dermatology 1988;26(1):22-27
The effect of long-term topical application of corticosteroids on rat cutaneous mast cells was examined under the light microscopy. Two potent corticosteroids, 0.05% clobetasol-17-propionate and 0.25% desoxymethasone, produced a remarkable decresse greater than 50% of pretreatment mast cell number by two weeks. Wheress a less potent corticosteroid, 0.1% hydrocotisone-17-valerate, produced a remarkable decrease greater than 50% of pretreatment mast cell number by four weeks. All corticosteroids produced a remarkable decrease greater than 80% of pretreatment mast cell number by six weeks. These results suggest that long-term topical application of corticosteroids may have the deleterious effects on cutsneous mast cells.
Adrenal Cortex Hormones
;
Animals
;
Desoximetasone
;
Mast Cells*
;
Microscopy
;
Rats*
;
Skin*
4.CLINICOPATHOLOGIC ANALYSIS OF THE PLEOMORPHIC ADENOMA.
Yeong Mi KIM ; Yong Gyoo LEE ; Chin Soo KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1997;23(4):716-727
The author studied on the 197 cases of the pleomorphic adenoma which had been diagnosed with biopsy during the period of 1985 to 1996 at the Kyungpook National University Hospital. This study contains the statistical analysis of the clinico-pathological findings such as sex, age, location, chief complaint, duration, treatment method, size, recurrence, and treatment department in relation to anatomical location. The result were as follows : 1. The treatment department in oxter were ENT(16.2%), GS(22.8%), OMFS(18.8%), PS(12.2%). 2. The incidence of pleomorphic adenoma were parotid gland(57.8%), palatal salivary gland(20.3%), submandibular gland(17.2%), other minor salivary glands(4.5%). 3. The tumors were more common in females than males, with a male to female ratio of 1 : 1.85. 4. The peak age of ocurrence was in the forth decade. 5. The duration of the most cases were less than 5 years. 6. Although the size of the tumors was variable, the incidence was highest between 3cm and 4cm(25.4%). 7. The most prevalent chief complaint was swelling(94.9%). 8. Conservative treatment was performed 30.0%, and radical treatment was employed 70.0%. 9. The recurrence rate is 8.1%, and recurrence used to be relatively common with conservative treatment. 10. The rate of malignant transformation is 1%. 11. The anatomical location has no relationship with the factors of sex, duration, and malignant transformation. 12. There was statistical significance on the anatomical location to the treatment department, age, chief complaint, size, treatment method, recurrence (P<0.05).
Adenoma, Pleomorphic*
;
Biopsy
;
Female
;
Gyeongsangbuk-do
;
Humans
;
Incidence
;
Male
;
Recurrence
5.Changes of the Immunocompetent Cells in the Lymphatic Organs of the Rabbits with Dermatitis Induced by the Hyman Serum.
Hoon LEE ; Byung In RO ; Chin Yo CHANG ; Tae Soo PARK
Korean Journal of Dermatology 1979;17(1):73-79
This study was performed in order to explore the immunologic relationship between the skin lesions induced by the human serum and the lymphatic organs. For these purposes, the authors induced the dermatitis in the rabbits by the injections of pooled human serum with Freunds complete adjuvant into the skin, and administered prednisolone and azathioprine as immunosuppressive drugs to the rabbits. Immunologic asmy was performed by the measurement of the plasma ceIls and immunogobulin-bearing B lymphocytes in lymph node and spleen. The results were as follows: 1. By the injections of human serum pyroninophilic cells and immunoglobulining B lymphocytes in lymph node and spleen were increased. 2. By the administrations of prednisolone and azathioprine, pyroninophilic cells and immunoglobulin-bearing B lymphocytes in lymph node and spleen were all decre RSCd.
Azathioprine
;
B-Lymphocytes
;
Dermatitis*
;
Humans
;
Immunoglobulins
;
Lymph Nodes
;
Plasma
;
Prednisolone
;
Rabbits*
;
Skin
;
Spleen
7.Soft Tissue Change After Single Jaw(mandible) Surgery in Skeletal Class III Malocclusion.
Kwang Soo PARK ; Hee Kyung LEE ; Byung Rho CHIN
Yeungnam University Journal of Medicine 1997;14(1):197-208
The purpose of this study was to evaluate the amount and interrelationship of the soft and hard tissue change after mandibular setback surgery in skeletal Class III malocclusion. The sample consisted of 25 adult patient (12 male and 13 female) who had severe anteropostrior skeletal discepancy. These patient had received presurgical orthodontic treatment and surgical treatment which is bilateral sagittal split ramus osteotomy. The presurgical and postsurgical lateral cephalograms were evaluated. The computerized statistical analysis was carried out with SPSS/PC program. The result were as follows: 1. After mandibular bilateral sagittal split ramus osteotomy, lower facial soft tissue horizontal posterior changes were high significance value. but vertical soft tissue changes were low significance value. 2. After mandibular bilateral sagittal split ramus osteotomy, relative upper lip protrusion increased(p<0.01) and relative lower lip protrusion decreased(p<0.01) and lower facial soft tissue thickness increased(p<0.01).
Adult
;
Male
;
Female
;
Humans
8.Ultrasonographic findings of uterine myoma
Jong Beum LEE ; Kie Hwan KIM ; Soo Yil CHIN
Journal of the Korean Radiological Society 1984;20(2):339-345
Utrerine myoma is one of the most commonly encountered gynecologic problem in daily ultrasonographic practice,and is one of the few conditions with which specific histologic diagnosis is possible by ultrasonography in selected patients as well. We recently analysed ultrasonograms of 132 cases of uterine myoma and 31 cases thatshowed similar ultrasonographic findings of myoma, histopathologically verified in both cases. The results were as follows. 1. The diagnostic accuracy by ultrasonography was 93%. 2. The most common ultrasonographic findings of uterine myoma were nodular enlargement of uterus and irregular internal echo texture changes. 3. It was not possible to differentiate the various kinds of secondary degeneration by ultrasonography, except for calcification and cystic change. 4. It was usually unable to differentiate solitary from multiple myoma, and subserosal,interstitial and submucosal types from each other by ultrasonographic findings alone, except for the usual cases of exophytically growing subserosal mass. 5. The most frequent disease that is hard to differentiate from small uterine myoma was adenomyosis, and therefore it is considered necessary to include the adenomyosis in differential diagnosis in the diagnosis of myoma causing moderatelly enlarged uterus.
Adenomyosis
;
Diagnosis
;
Diagnosis, Differential
;
Humans
;
Leiomyoma
;
Myoma
;
Ultrasonography
;
Uterus
9.Balloon Dilatation and Bougienage of Post-operative Anastomotic Site Stricture of Upper G-I Tract.
Ki Soo KIM ; Young Soo DO ; Byung Hee LEE ; Kie Hwan KIM ; Soo Yil CHIN
Journal of the Korean Radiological Society 1994;31(2):251-254
PURPOSE: We evaluated the effectiveness of balloon dilatation and bougienage of post operative anastomotic stricture of upper G-I tract. MATERIALS AND METHODS: We performed 22 balloon dilatation and 24 Bougienage in 40 patients of post operative anastomotic stricture. The causes of operation were esophageal cancer(n=20), stomach cancer(n=16), laryngeal cancer(n=2), chemical(n=2) strictures. RESULTS: Successful dilatations of the anastomotic site stricture were achieved during the procedure in 38 patients(95%). There was one case of esophageal perforation as a complication. CONCLUSION: Esophageal balloon dilatation and Bougienage are safe and effective method for post operative anastomotic site stricture of upper G-I tract.
Constriction, Pathologic*
;
Dilatation*
;
Esophageal Perforation
;
Humans
;
Stomach
10.Congenital Absence of Infrarenal IVC and lilac Venous System: Unusual Collateral Pathways.
Young Soo DO ; Byung Hee LEE ; Kie Hwan KIM ; Jin Joo LEE ; Soo Yil CHIN
Journal of the Korean Radiological Society 1994;30(5):849-851
We present a case with congenital absence of the infrarenal portion of inferior vena cava and lilac venous system, showing unusual venous collaterals including the left ovarian venous collateral via parametrial venous complex, and a mesenteric-periureteric venous connection. The venous collateral pathways were demonstrated by computed tomography and venography.
Phlebography
;
Vena Cava, Inferior