1.Characteristics of Magnetic Resonance(M.R.) and Comprehension of its Imaging Mechanism.
Jae Chun CHANG ; Mi Soo HWANG ; Son Yong KIM
Yeungnam University Journal of Medicine 1987;4(1):1-15
Magnetic resonance (MR) is rapidly emerging technique that provides high quality images and potentially provides much more diagnostic information than do conventional imaging modalities. MRI is conceptually quite different from currently used imaging methods. The complex nature of MRI allows a great deal of flexibility in image production and available information, and key points are as follows. 1. MR offers a non-invasive technique with which to generate in vivo human images without ionizing radiation and with no known adverse biological effects. 2. Imaging mechanism of MRI is quite different from conventional imaging modality and for more accurate diagnostic application, It is necessary for physician to understand imaging mechanism of MRI 3. M.R. makes available basic chemical parameters that may provide to be useful for diagnostic medical imaging and more specific pathophysiologic information which are not available by alternate techniques. 4. M.R. can be produced by number of different methods. This flexibility allows the imaging technique to be applicated for particular clinical purpose. Multiplanar and three dimensional imaging may extend the imaging process beyond the single section available with current CT. 5. Future directions include efforts to; a. Further development of hard ware b. More fastening scan time c. Respiratory and cardiac gated imaging d. Imaging of additional nuclei except hydrogen. e. Further development of contrast media f. MR in vivo spectroscopy g. Real time MR imaging
Comprehension*
;
Contrast Media
;
Diagnostic Imaging
;
Humans
;
Hydrogen
;
Magnetic Resonance Imaging
;
Pliability
;
Radiation, Ionizing
;
Spectrum Analysis
2.Congenital Ileal Atresia in Newborn.
Young Soo HEO ; Chang Sig KIM ; Son Moon SHIN
Yeungnam University Journal of Medicine 1994;11(1):35-41
Newborns with ileal atresia frequently present with abdominal distension, bilious vomiting, and failure to pass meconium. Diagnosis is usually established on plain x-ray of the abdomen by the findings of distended small bowel loops and air-fluid levels. In the period of October 1988 to February 1994, 8 patients with congenital ileal atresia were operated and the following results were obtained. 1. Eight patients were comprise of 4 males and 4 females, the ratio of male and female was 1 : 1. 2. Six patients(75%) had been admitted to our hospital during three days of life. 3. Congenital ileal atresia was in 8 cases : Type I in two(25%), Type II in two(25%), Type III a in three(37.5%), Type III b in one(12.5%). 4. There was one premature patient who was small for gestational age. 5. Overall, abdominal distension and bilious vomiting occurring in seven patients, were frequent presenting complaints. 6. Diagnosis was possible with clinical symptom and simple abdomen. 7. Operative treatment was undertaken as soon as the diagnosis was made. In seven cases a primary end-to-end anastomosis was performed after resection of dilated proximal loop. 8. A total of four associated congenital anomalies were found in one patient. 9. Postoperative complications occurred in three cases(37.5%).
Abdomen
;
Diagnosis
;
Female
;
Gestational Age
;
Humans
;
Infant, Newborn*
;
Male
;
Meconium
;
Postoperative Complications
;
Vomiting
3.A rural health study through screening approaches.
Gil Soo SON ; Yong Tae YUM ; Soung Hoon CHANG
Korean Journal of Epidemiology 1991;13(2):197-203
No abstract available.
Mass Screening*
;
Rural Health*
4.Bullous Pemphigoid Responding to DDS.
Kwang Soo KIM ; Ji Soo KIM ; Kyung Jin RHIM ; Sook Ja SON ; Chang Woo LEE
Korean Journal of Dermatology 1982;20(6):913-917
Bullous pemphigoid is a chronic and relatively benign subepidermal blistering disease and is generally considered not to be a sulfa-responsive dermatosis. As a rule, bullous dermatosis that excellently responded to sulfapyridine and sulfones was considered by some to be diagnostic of dermstitis herpetiformia. In 1977, Person and Rogers described 6 cases of bullous pemphigoid responded to sulfapyridine and sulfones. These sulfa-responsive cases were younger than ordinary bullous pemphigoid patients and the histopathologic findings showed prevalence of the neutrophilic infiltration. In this report, the patient who diagnosed as bullous pemphigoid by immunofluorescent studies has younger onset (38 years of age) than usual bullous pemphigoid and histopatbologic findings showed dense neutrophilic infiltrations. The patient was treated with 100-200mg of DDS for 2 months and the skin lesions completely disappeared.
Blister
;
Humans
;
Neutrophils
;
Pemphigoid, Bullous*
;
Prevalence
;
Skin
;
Skin Diseases
;
Sulfapyridine
;
Sulfones
6.CT findings of the Mediastinal tumors.
Ho Son CHUNG ; Sang Jin LEE ; Mi Young SON ; Hyuk Po KWON ; Mi Soo HWANG ; Son Yong KIM ; Jae Chun CHANG ; Bok Hwan PARK
Yeungnam University Journal of Medicine 1989;6(2):79-90
Computerized Tomography is now well established and important noninvasive method of diagnosting mediastinal mass lesions because of its superior imaging of their size, location and internal composition. Authors analyzed and present CT findings of 30 surgically proven mediastinal tumors and cysts that were studied and treated at the Yeungnam University Hospital during recent 6 years. The most common tumor was thymoma (9 cases), and teratoma (6 cases), lymphoma (6 cases), bronchogenic cyst (4 cases), neurogenic tumor (4 cases), pericardial cyst (1 case) were next in order of frequency. There were 5 cases of thymoma showing homogenous solid density mass, 2 cases were malignant thymoma and myasthenia gravis was present in 2 cases. A case of thymolipoma and a case of thymic carcinoma were included. All teratomas were cystic masses but pathognomonic fat, and calcified density were seen only in 4 cases. 5 cases were located in anterior mediastinum and 1 case was in posterior mediastinum. Lymphoma (3 Hodgkin's and 3 non-Hodgkin's) appeared as irregular lobulated mass in anterior mediastinum. Neurogenic tumor (2 ganglioneuroma and 2 neurilemmoma) appeared as homogenous density mass located in posterior mediastinum. Among the 4 bronchogenic cysts, 2 were located in retrotracheal area, 1 was located in subcarinal and 1 was in parathoracic area. One case of pericardial cyst was oval shaped cystic mass located in left pericardiac border.
Bronchogenic Cyst
;
Ganglioneuroma
;
Lymphoma
;
Mediastinal Cyst
;
Mediastinum
;
Methods
;
Myasthenia Gravis
;
Teratoma
;
Thymoma
7.The Effects of Intranasal Midazolam on Preanesthetic Sedation in Children.
Young Ju KIM ; Cheoel Oh KIM ; Yoon Hee KIM ; Soo Chang SON
Korean Journal of Anesthesiology 1997;33(4):627-632
BACKGROUNDS: This study was performed to determine the onset time and dose of intranasal midazolam used for preanesthetic sedation in children. METHODS: The children were randomly allocated to recieve one of three medications via the nasal route in a double blind manner. Group I: patients were given normal saline 0.2 ml/5kg, Group II: patients were given midazolam 0.2 mg/kg, Group III: patients were given midazolam 0.3 mg/kg. RESULTS: The cardiovascular and SpO2 changes were not significantly different among the patients of the three groups. The sedation score was greater in group II compared with group I from 5 minute after administration (1.9 vs 2.7, p<0.05). postanesthetic recovery score (PARS) was not significantly different among the three groups. CONCLUSIONS: It is suggested that intranasal midazolam (0.2 mg/kg) produces anxiolysis and sedation in children with rapid onset.
Child*
;
Humans
;
Midazolam*
8.Effects of c -Fos Immunoreactivity on Central Nervous System after Administration of Aspirin.
Chang Mok SON ; Chul Hong KIM ; Ki Soo YOO
Korean Journal of Physical Anthropology 2001;14(1):17-27
Aspirin is one of the popular non -steroid anti -inflammatory drugs used in the management of pain. This study was performed to investigate the effects of aspirin on c -Fos expression in rat CNS after inducing somatic pain with formalin. Male S.D. rats were injected subcutaneously with 0.1 ml of 5% formalin in the plantar surface of right hindpaw. For experimental group, aspirin was administered orally before injection of formalin. Asprin -untreated group was utilized as the control group. Rats were sacrificed at 0.5, 1, 2, 6 and 24 hours after formalin injection. Rat brains were removed and sliced in rat brain matrix. Brain slices were coronally sectioned at interaural 5.70 ~6.70 mm. Serial sections were immunohisto-chemically reacted with polyclonal c -Fos antibody. The numbers of c -Fos protein immunoreactive neurons in the cingulate cortex, primary somatosensory area, and hippocampus were counted and analyzed statistically with Mann - Whitney U test. Results were as follows: 1. Higher numbers of c -Fos immunoreactive neurons were found in the cingulate cortex, primary somatosensory area and hippocampus. 2. Both aspirin -treated and -untreated groups, numbers of c -Fos immunoreactive neurons were significantly higher all time points than formalin -untreated group, which peacked at 2 hours. 3. The numbers of c -Fos immunoreactive neuron of the aspirin -treated group were less compared to the aspirin - untreated group at each time point. In conclusion, these results provide some basic knowledge in understanding the mechanism and control of formalin - induced somatic pain.
Animals
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Aspirin*
;
Brain
;
Central Nervous System*
;
Formaldehyde
;
Gyrus Cinguli
;
Hippocampus
;
Humans
;
Male
;
Neurons
;
Nociceptive Pain
;
Rats
9.Expression of HLA-DR antigen in different histologic types of gastric carcinoma.
Soo Sang SON ; Young Hun KIM ; In Ho KIM ; Eun Sook CHANG ; Sang Pyo KIM
Journal of the Korean Cancer Association 1993;25(6):818-825
No abstract available.
HLA-DR Antigens*
10.Chromosomal abnormalities found in the large bowel cancer and oncogene expression.
Dong Hwi YANG ; Soo Sang SON ; Joong Sin KANG ; Sung Ick CHANG
Journal of the Korean Cancer Association 1993;25(2):182-195
No abstract available.
Chromosome Aberrations*
;
Oncogenes*