1.A study on osteoblast-like cell responses to surface-modified titanium.
Min ah HONG ; Yung Soo KIM ; Chang Whe KIM ; Kyung Su JANG ; Jae Il LEE
The Journal of Korean Academy of Prosthodontics 2003;41(3):300-318
STATEMENT OF PROBLEM: The success of implants depends on intimate and direct contact of implant material on bone tissue and on functional relationship with soft tissue contact. Creation and maintenance of osseointegration depend on the understanding of the tissue's healing, repairing, and remodeling capacity and these capacities rely on cellular behavior. Altering the surface properties can modify cellular responses such as cell adhesion, cell motility, bone deposition. Therefore, various implant surface treatment methods are being developed for the improved bone cell responses. PURPOSE: The purpose of this study was to evaluate the responses of osteoblast-like cells to surface- modified titanium. MATERIALS AND METHODS: The experiment was composed of four groups. Group 1 represented the electropolished surface. Group 2 surfaces were machined surface. Group 3 and Group 4 were anodized surfaces. Group 3 had low roughness and Group 4 had high roughness. Physicochemical properties and microstructures of the d iscs were examined and the responses of osteoblast-like cells to the discs were investigated. The microtopography was observed by SEM. The roughness was measured by three-dimension roughness measuring system. The microstructure was analyzed by XRD, AES. To evaluate cell responses to modified titanium surfaces, osteoblasts isolated from calvaria of neonatal rat were cultured. Cell count, morphology, total protein measurement and alkaline phosphatase activities of the cultures were examined. RESULTS AND CONCLUSION: The results were as follows 1. The four groups showed specific microtopography respectively. Anodized group showed grain structure with micropores. 2. Surface roughness values were, from the lowest to the highest, electropolished group, machined group, low roughness anodized group, and high roughness anodized group. 3. Highly roughened anodized group was found to have increased surface oxide thickness and surface crystallinity. 4. The morphology of cells, flattened or spherical, were different from ach other. In the electropolished group and machined group, the cells were almost flattened. In two anodized groups, some cells were spherical and other cells were flattened. And the 14 day culture cells of all of the groups were nearly flattened due to confluency. 5. The number of attached cells was highest in low roughness anodized group. And the machined group had significantly lower cell count than any other groups(P<.05). 6. Total protein contents showed no difference among groups. 7. The level of alkaline phosphatase activities was higher in the anodized groups than electropolished and machined groups(P<.05).
Alkaline Phosphatase
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Animals
;
Bone and Bones
;
Cell Adhesion
;
Cell Count
;
Cell Movement
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Edible Grain
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Crystallins
;
Osseointegration
;
Osteoblasts
;
Rats
;
Skull
;
Surface Properties
;
Titanium*
2.6 cases of postinfectious opsoclonus in adult.
Eun Ah LEE ; In Soo JOO ; Myeong Soo OH ; Jang Sung KIM ; Kyoon HUH
Journal of the Korean Neurological Association 1997;15(6):1285-1292
Opsoclonus is the involuntary, repetitive, rapid conjugate ocular movements occurring in all directions that are irregular in amplitude and frequency. The cause of opsoclonus are idiopathic, paraneoplastic or postinfectious. Opsoclonus of the postinfectious origin often accompanies other abnormal movements such as tremor, myoclonus and ataxia, and shows a relatively benign course with good response to steroid. Six patients who suffered from myalgia, chilling, fever, cough and generalized weakness fior one to two weeks prior to the admission, experienced visual disturbance, gait unsteadiness and clumsiness of the upper extremities,, Prominent opsoclonus, tremulous movements of trunk and limbs, and intermittent myoclonus were observed. These symptoms markedly improved several days following the use of ACTH or dexametasone.
Adrenocorticotropic Hormone
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Adult*
;
Ataxia
;
Cough
;
Dyskinesias
;
Extremities
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Fever
;
Gait
;
Humans
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Myalgia
;
Myoclonus
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Ocular Motility Disorders*
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Tremor
;
Upper Extremity
3.6 cases of postinfectious opsoclonus in adult.
Eun Ah LEE ; In Soo JOO ; Myeong Soo OH ; Jang Sung KIM ; Kyoon HUH
Journal of the Korean Neurological Association 1997;15(6):1285-1292
Opsoclonus is the involuntary, repetitive, rapid conjugate ocular movements occurring in all directions that are irregular in amplitude and frequency. The cause of opsoclonus are idiopathic, paraneoplastic or postinfectious. Opsoclonus of the postinfectious origin often accompanies other abnormal movements such as tremor, myoclonus and ataxia, and shows a relatively benign course with good response to steroid. Six patients who suffered from myalgia, chilling, fever, cough and generalized weakness fior one to two weeks prior to the admission, experienced visual disturbance, gait unsteadiness and clumsiness of the upper extremities,, Prominent opsoclonus, tremulous movements of trunk and limbs, and intermittent myoclonus were observed. These symptoms markedly improved several days following the use of ACTH or dexametasone.
Adrenocorticotropic Hormone
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Adult*
;
Ataxia
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Cough
;
Dyskinesias
;
Extremities
;
Fever
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Gait
;
Humans
;
Myalgia
;
Myoclonus
;
Ocular Motility Disorders*
;
Tremor
;
Upper Extremity
4.Medical Facilities Utilization According to Health Status Measured by SF-36 in Male Workers.
Seong Ah KIM ; Ki Soo PARK ; Mi Kyung JANG ; Sin KAM
Korean Journal of Occupational and Environmental Medicine 2006;18(4):272-283
OBJECTIVES: This study was performed to examine the health status measured by SF-36 and medical facilities utilization according to the health status measured by SF-36 in male workers. METHODS: A self-administered questionnaire survey was administered to 786 male workers. RESULTS: In bivariate analysis, physical functioning score was significantly different among the workers according to age, educational level, economic level, and job type. The bodily pain score and general health score were significantly different according to the workers'economic level and job type. The vitality score was significantly different according to the workers'age, educational level, economic level, and job type. The social functioning score was significantly different according to the workers'age, marital status, economic level, and job type. The role limitation emotion score was significantly different according to the workers'age, marital status, and job type. The mental health score was significantly different according to the workers'marital status, economic level, and job type (p<0.05). The SF-36 scores increased with higher workers'self-rated health status (p<0.05). The self-rated current health status of the workers was good when their economic status was high, their previous year health status was good and their SF-36 score was high (p<0.05). The rates of morbidity incidence and medical facilities utilization for 1 year were lower when workers'SF-36 score was high (p<0.05). CONCLUSIONS: In consideration of the above findings, SF-36 is suitable to measure health status and predict the medical utilization.
Humans
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Incidence
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Male*
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Marital Status
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Mental Health
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Questionnaires
5.Association between Parents' Country of Birth and Adolescent Depressive Symptoms: the Early Stages of Multicultural Society.
Jieun JANG ; Eun Cheol PARK ; Sang Ah LEE ; Young CHOI ; Yoon Soo CHOY ; Woorim KIM ; Sung In JANG
Journal of Korean Medical Science 2018;33(15):e116-
BACKGROUND: This study aims to determine whether significant associations exist between the parents' country of birth and adolescent depressive symptoms in the early stages of a multicultural society. METHODS: We used data from the 2012–2016 Korea Youth Risk Behavior Web-based Survey, which included responses from 327,357 individuals. Participants were classified into groups according to their parent's country of birth. Logistic regression analysis was used to examine the significance of the associations. RESULTS: Adolescents whose parents were born abroad are more likely to have depressive symptoms (odds ratio [OR] = 1.68; 95% confidence interval [CI], 1.33–2.12) than adolescents whose parents were native Koreans. Respondents whose father was born in North Korea or Japan or Taiwan show greater odds of depressive symptoms than respondents whose parents were native Korean. CONCLUSION: Adolescents whose parents were born abroad are more likely to have depressive symptoms. Multicultural family support policies should be implemented in consideration of the characteristics of the parents' country of birth.
6.Comparative study of fracture strength depending on the occlusal thickness of full zirconia crown.
Soo Ah JANG ; Yoon Young KIM ; Won Hee PARK ; Young Soo LEE
The Journal of Korean Academy of Prosthodontics 2013;51(3):160-166
PURPOSE: The purpose of this study was to compare the fracture strength of traditional metal-ceramic crowns and full zirconia crowns according to the occlusal thickness. MATERIALS AND METHODS: A mandibular first molar resin tooth was prepared with 1.5 mm occlusal reduction, 1.0 mm rounded shoulder margin and 6degrees taperness in the axial wall. Duplicating the resin tooth, 64 metal dies were fabricated. 48 full zirconia crowns were fabricated using Prettau zirconia blanks by ZIRKONZAHN CAD/CAM and classified into six groups according to the occlusal thickness (0.5 mm, 0.6 mm, 0.7 mm, 0.8 mm, 0.9 mm, 1.0 mm). 16 metal-ceramic crowns were fabricated and classified into two groups according to the occlusal porcelain thickness (1.0 mm, 1.5 mm). All crowns were cemented on each metal die and mounted in a universal testing machine. The load was directed at the functional cusp of each specimen until catastrophic failure occurred. One-way ANOVA, Tukey multiple comparison test (alpha=.05) and t-test (alpha=.05) were used. RESULTS: The results were as follows. 1. The test 1 group (646.48 N) showed the lowest fracture strength (P<.05), and the value of the test 2.3.4.5 groups (866.40 N, 978.82 N, 1196.82 N, 1222.41 N) increased as thickness increased, but no significant difference were found with the groups (P>.05). The value of test 6 group (1781.24 N) was significantly higher than those of the other groups (P<.05). 2. There were no significant differences of the fracture strength of metal ceramic crowns according to occlusal porcelain thickness 1.0 mm (2515.71 N) and 1.5 mm (3473.31 N) (P<.05). CONCLUSION: Full zirconia crown needs to be 1.0 mm or over in occlusal thickness for the posterior area to have higher fracture strength than maximum bite force.
Bite Force
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Ceramics
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Collodion
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Crowns
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Dental Porcelain
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Molar
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Shoulder
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Tooth
;
Zirconium
7.Rumpel-Leede phenomenon associated with noninvasive blood pressure monitoring: A case report.
Yeon Soo JEON ; Yong Shin KIM ; Jung Ah LEE ; Kwon Hui SEO ; Jang Hyeok IN
Korean Journal of Anesthesiology 2010;59(3):203-205
We report a case of Rumpel-Leede (RL) phenomenon, - acute dermis capillary rupture, secondary to noninvasive blood pressure (NIBP) monitoring in a patient with type 2 diabetes mellitus (DM) and hypertension. The first most likely cause is vascular fragility in microangiopathy as a result of DM and chronic steroid use. The second is the increased venous pressure during cycling of the blood pressure cuff in a hypertensive state. Anesthesiologists need to be aware that acute dermal capillary rupture, although rare, can occur in patients with long-standing DM, hypertension and chronic steroid use.
Blood Pressure
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Capillaries
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Dermis
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Diabetes Mellitus, Type 2
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Humans
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Hypertension
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Rupture
;
Venous Pressure
8.Copycat Suicide Induced by Entertainment Celebrity Suicides in South Korea.
Soo Ah JANG ; Ji Min SUNG ; Jin Young PARK ; Woo Taek JEON
Psychiatry Investigation 2016;13(1):74-81
OBJECTIVE: Throughout the past several years, there have been a number of entertainment celebrity suicides in South Korea. The aim of this study was to investigate the clustering of suicides following celebrities' suicides in South Korea from 2005 to 2008, particularly according to certain characteristics. METHODS: Seven celebrity suicides were examined and defined using the Korean Integrated Newspaper Database System (KINDS) and from these, we considered four affected periods occurring 28 days after each celebrity's suicide. A Poisson time-series autoregression model was used to estimate the relative risk of the total suicide number for each affected period from 2005 to 2008. Logistic regression analysis was performed to investigate whether there were specific increases in the numbers of suicides in subgroups matching each celebrity. RESULTS: There were significant increases in the risk of suicide during the affected periods. Remarkable increases were found in the subgroups matching each celebrity, especially in the group in which all factors (sex, age, and method) were similar. CONCLUSION: This study provides confirmation that a significant copycat effect was induced by these celebrities' suicides, especially among people who identified more with the celebrities. This implies that countermeasures for upright media coverage of celebrity suicides should be discussed and practiced properly in South Korea.
Imitative Behavior
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Korea*
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Logistic Models
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Mass Media
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Periodicals
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Republic of Korea
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Risk Factors
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Suicide*
9.A three-dimensional photogrammetric analysis of the facial esthetics of the Miss Korea pageant contestants.
Kab Soo JANG ; Mohamed BAYOME ; Jae Hyun PARK ; Ki Ho PARK ; Hong Beom MOON ; Yoon Ah KOOK
The Korean Journal of Orthodontics 2017;47(2):87-99
OBJECTIVE: The aims of this study were to measure and compare the facial dimensions of the Miss Korea pageant contestants and a selected group of women from the general population by using three-dimensional (3D) image analysis, as well as to compare various facial ratios to the golden ratio within each group. METHODS: Three-dimensional images of 52 Miss Korea pageant contestants (MK group) and 41 young female adults selected from the general population (GP group) were acquired. Fifty-four variables and ratios were measured and calculated. Intergroup comparisons were performed using multivariate analysis of variance. RESULTS: Compared to the GP group, the MK group showed greater total facial height and eye width, lesser lower-facial height, and lesser facial, lower-facial, and nasal widths. Moreover, compared to the GP group, the MK group had more protruded noses with greater nasolabial angle, greater vertical curvature of the foreheads, lesser horizontal curvature of the cheek, and lesser lower-lip-and-chin volume. CONCLUSIONS: The MK group had longer faces but smaller lower lips and chins than did the GP group. The golden ratio was not matching the current facial esthetic standards. These data might be beneficial for treatment planning of patients undergoing orthognathic and plastic surgeries.
Adult
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Cheek
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Chin
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Esthetics*
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Female
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Forehead
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Humans
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Imaging, Three-Dimensional
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Korea*
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Lip
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Multivariate Analysis
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Nose
;
Plastics
10.An Association between Working Schedules and Depression in Public Sector Employees.
Hyeon Taek HEO ; Dong Won KIM ; Jong Seok LEE ; Hyeon A JO ; Seong Sil JANG ; Soo Young KIM ; In Ah KIM
Korean Journal of Occupational and Environmental Medicine 2012;24(4):347-355
OBJECTIVES: This study determined the work schedules of public project workers who work an irregular shift and assessed the effect of these schedules on depression. METHODS: Study subjects were 2934 laborers who are members of seven labor unions. Each was given a questionnaire requesting basic personal information, habits, socioeconomic status, and work schedules. Information gathered on work schedules included daytime, nighttime, and weekend work hours. Depression was evaluated using the Beck Depression Inventory (BDI), with Laborers who checked "not depressed" and "slightly depressive" categorized to a low-risk group, whereas laborers who checked "depressed" and "severely depressed" were categorized to a high-risk group. We used the Chi-square test and multivariate logistic regression to examine associations between work schedules and depression. RESULTS: Laborers on an irregular work schedule averaged 47.8 hours/week and laborers who working over 48 hours/week comprised over half (54.5%) of the total population. Laborers performing night work, Sunday work, and Saturday work more than once in a month made up 25.7%, 30.8% and 33.5% of the examined population, respectively. A high-risk for depression was identified in 10.4% of laborers. Using logistic regression, depression was statistically associated with working : over 10 hours a day (OR=1.63, 95% CI 1.10~2.43), night work (OR=2.20, 95% CI 1.46~3.32), Sunday work (OR=1.81, 95% CI 1.15~2.85) and Saturday work (OR=1.82 95% CI 1.18~2.82). CONCLUSION: A significant number of laborers with irregular working shifts work long hours and on weekends. Depression was significantly associated with this type of work schedule.
Appointments and Schedules
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Depression
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Humans
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Labor Unions
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Logistic Models
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Public Sector
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Questionnaires
;
Social Class