1.A Correlative Study on Multiplanar Coronal Reconstructed and Direct Coronal Images of Orbit and Paranasal Sinuses with Multi-slice Helical CT
Songguo CHEN ; Lumin MING ; Fanhua MENG ; Longchun XU
Journal of Practical Radiology 1992;0(11):-
Objective To assess the quality of coronal multi-planar reconstructed versus direct coronal scan images and to confirm whether the multiplanar reconstructed image can replace coronal scan.Methods One hundred and sixteen patients with orbital and paranasalsinuses disease were examined with GE Lightspeed plus 4 slices helical CT.All patients had transvers scan,and the coronal multiplannarreconstructed images were reformatted basis on transverse scan.All reformatted and scanned images were evaluated by the senior radiologists.Results In 116 cases,simultaneously multiplanar reconstructed images were performed in 60 cases,the quality of reformatted coronal imageswas similar to direct coronal scan in revealing normal anatomy and lesions of orbit and paranasal sinuses,all images were excellent andimaging quality was grade Ⅰ.54 cases couldn't be undergone direct coronal scan but reformatted coronal images also acquired the effect of diagnosis(32 cases were grade Ⅰ and 3 cases were grade Ⅱ on quality).Conclusion Direct coronal scan can be substitued by multiplanar reconstruction of multi-slice helical CT scan for orbit and paranasal sinuses.
2.Expression and role of CD4+CD25+CD127low/-T cells of the peripheral blood in rheumatoid arthritis patients
Dongmei LI ; Xiangpei LI ; Xiaomei LI ; Shushan ZHAO ; Zhu CHEN ; Yan MA ; Songguo ZHENG
Chinese Journal of Rheumatology 2009;13(4):259-262
Objective To investigate the expression of regulatory T cells in the peripheral blood of rheumatoid arthritis patients and to explore the possibility of using CD127 instead of FOXP3 in the study of regulatory T cells. Methods Thirty-two patients with active rheumatoid arthritis (RA) [ including 20 patients who hadn't been treated with disease modifying antirheumatic drugs (DMARDs) and 12 patients whose disease were poorly improved after DMARDs therapy], 25 patients with primary Sjogren's syndrome (pSS) and 24 healthy controls were selected. The percentages of CD4+CD25high, CD4+CD25+CD127low/'- and CD4+CD25+ FOXP3+T cells were analyzed by 3-color flow cytometry. Meanwhile, the levels of CRP, ESR, immunoglobulin and complement were measured. Results Percentages of CD4+CD25+CD127low/-T cells and CD4+CD25+FOXP3+ T cells in RA patients were significantly lower than those of healthy controls (P<0.01 for each category of T cells),but the percentage of CD4+CD25high T cells didn't show significant changes (P>0.05). The expression of CD4+CD25+CD127ow/- and CD4+CD25+FOXP3+T cells showed no difference between RA and pSS patients (P> 0.05 for each). Differences of the three group cells between untreated RA patients and poorly-improved RA patients were not significant (P>0.05 for each case). CD4+CD25+CD127low/-T cells were positively associated with CD4+CD25+FOXP3+T cells (r=0.698, P=0.001), but the two groups had no correlation with the levels of CRP, ESR and anti-CCP antibody and RF (P>0.05 for each case). Conclusion The percentage of CD4+CD25+CD127low/-T cells is decreased in the peripheral blood of active RA patients and positively correlates with CD4+CD25+FOXP3+T cells.It suggests that CD127 may be an ahemative marker of FOXP3 in the study of Treg cells.
3.The preliminary study of psychophysiological test technique in the simulative identification of artificial injury and malingering
Xinfeng HUANG ; Kefang ZHENG ; Kaili CHEN ; Songguo HE ; Bugao XIE
Chinese Journal of Forensic Medicine 2017;32(6):593-595,602
Objective To explore the application value of psychophysiological test technique in identification of artificial injury and malingering. Methods CQT test was conducted on 50 students with camouflaged pain and tympanic membrane perforation, respectively, using Tongfang Shenhuo Polygraph Tester (TH 4.0.0.15). T-test and χ2 test were adopted for data analysis. Results The accuracy rate of honest group was higher than that of lying group (P<0.01). There were no significant differences in accuracy rates between automatic scoring and manual scoring,and so were that between mask pain problems' testing and tympanic membrane perforation problems' testing. Conclusion This experiment provides a good research basis for the subsequent real case test.
4.Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development.
Lin ZHAO ; Songguo XUE ; Zhongyuan YAO ; Juanzi SHI ; Biaobang CHEN ; Ling WU ; Lihua SUN ; Yao XU ; Zheng YAN ; Bin LI ; Xiaoyan MAO ; Jing FU ; Zhihua ZHANG ; Jian MU ; Wenjing WANG ; Jing DU ; Shuai LIU ; Jie DONG ; Weijie WANG ; Qiaoli LI ; Lin HE ; Li JIN ; Xiaozhen LIANG ; Yanping KUANG ; Xiaoxi SUN ; Lei WANG ; Qing SANG
Protein & Cell 2020;11(12):921-927