Objective To study relationship between blood-glucose change and prognosis of the patients after severe traumatism.Methods 70 cases severe traumatic emergency patients selected tested the level of blood-glucose instantly when they presented themselves to the clinic after injury,used saccharimether and blood-glucose test paper provided by the Johnson Limited Corporation,and 30 slight traumatic emergency patients at the same time were selected as contrel.Result The blood-glucose after severe traumatic were markedly higher than that of slight traumatic group,which have significance(P

Objective To develop the fluorescence molecular imaging system and obtain the 3D images of near-infrared fluorescent probe in tissue-like solution.Methods Weak optical signals were acquired with hypothermal cooled CCD camera.The system captured the fluorescent images of different projections at rotating the tissue phantom.The photon propagation in tissue followed the diffusion approximation theory.The 3D image of probe was calculated with a fast reconstruction algorithm based on finite element approach.Results The imaging system could obtain the full-angle dense raw dataset.The reconstruction algorithm had capacity to recover the position and contour of the fluorescent target included in diffusive medium.Conclusion The results from phantom experiments are promising and show the potentials to act as a platform for in vivo fluorescence tomography.

Objective To analyze the elonal gene rearrangement and complementarity determining region 3 (CDR3) Repertoire of TCR β-chain in fine needle aspiration biopsy (FNAB) specimens of peripheral T-cell lymphoma. Methods The TCR CDR3 region genes of 24 TCR Vβ subfamilies were amplified by utilizing RT-PCR technology, and the CDR3 size lengths of TCR β-chain were analyzed with genesean technology for 4 healthy individuals and 4 patients with peripheral T-cell lymphoma. The clonality of T cells presumed by spectratyping was further confirmed by CDR3 sequencing. Results TCR β-chain presented specific repertoire skewing in 4 cases with peripheral T-cell lymphoma, and only 1-4 TCR Vβ subfamily T cells were identified, respectively. Clonal expanded T cells, including mono, bioclonal and oligoclonal trend patterns, in one or more Vβ subfamilies were found in all cases. The mono expanded T cells have different CDR3 amino acid sequences. Conclusion Characteristic T cells cloning proliferation and selected usage of TCR Vβ subfamily T cells were found in 4 cases with peripheral T-cell lymphoma. The sequences of CDR3 in different TCR clone proliferation are different.

Objective To analyze the incidence and clinical features of urothelial tumors in renal allograft recipients.Methods A retrospective analysis of 1042 patients received renal allografts who had taken immunosuppression for at least six months between 2006 and 2011 in The First Centre Hospital of Tianjin was performed.Results Eleven cases of uroepithelial tumors were diagnosed in the 1042 cases of renal transplantation ( 1.06％ ),of whom 9 cases were noticed by hematuria ( 81.8 ％ ),2 cases ( 18.2％ ) by medical examination.Six patients were diagnosed with multifocal urothelial carcinomas.Surgery was performed on all the patients with renal tumors and followed by chemotherapy or radiotherapy.Conclusion Malignancies in urinary tract after renal transplantation should be bore in mind.Early diagnosis is very important.The treatment options include reducing immunosuppressive agents and removing tumor lesions completely.

Objective:To investigate the effect of Genistein combined with cyclosporine A on chemokine receptor CXCR3 in rejection of cardiac allograft in rats.Methods:Heterotopic cervical heart transplantation was performed from Wistar rats to SD rats by using cuff-technique.The SD rat recipients were randomly divided into 3 groups.No treatment was adopted in the acute rejection( AR) group.Rats in the cyclosporine A(CsA) group were treated with cyclosporine A after transplantion.Rats in CsA+Genistein(C+G) group were treated with Genistein combined with cyclosporine A after transplantion.All the cardiac allografts were harvested at 7th day, and made into tissue slices.The HE-staining was used to observe the pathology changes of the allograft myocardia.And the expression of CXCR3 was detected with immunehistochemistry and Western blot.Results:The expression of CXCR3 strongly positively expressed in AR group.The degree of myocardial inflammation in C+G group and the expression of CXCR3 were much lower than the other two groups.Conclusion:Genistein combined with cyclosporine A can significantly relieve rejection of cardiac allograft by inhibiting the ex-pression of CXCR3.

Abstract: Objective To analyze the causes of foodborne illness outbreaks in Inner Mongolia, so as to provide reference for understanding systemic risks and formulating prevention and control measures. Methods Data on foodborne disease outbreaks in Inner Mongolia Autonomous Region from 2016 to 2021 were collected through the "Foodborne Disease Outbreak Monitoring System" for attribution analysis. Results A total of 591 outbreak events were included from 2016 to 2021. Single -dimensional attribution analysis showed that the main causes of foodborne disease outbreaks in this region were vegetables and vegetable products, and meat and meat products, respectively accounting for 20.5% (121/591) and 12.6% (75/591) of the total events. leading contributing factor was improper processing, accounting for 16.2%(96/591), and the main pathogenic factor was toxic plants and their toxins, accounting for 14.9%(88/591). Multi-dimensional attribution analysis showed that the highest number of outbreak events occurred in summer, with 290 cases accounting for 49.1% (290/591) of the total number of events. The eastern, central, and western regions also had the highest number of events in summer, accounting for 53.6% (180/336), 39.5% (60/152), and 48.5% (50/103) of the total number of events in this region, respectively. Among vegetables and vegetable products, improper processing led to the majority of outbreaks caused by toxic plants and their toxins, accounting for 58.7% (71/121) of total events. For meat and meat products, improper storage resulting in the most outbreaks of biological pollution, accounting for 16.0%(12/75) of the total number of meat and meat product incidents. Majorities of death cases were primarily due to accidental ingestion or misuse of non-food items (such as poisonous mushrooms), comprising 38.5% (5/13) of total deaths. Conclusions The main food, triggering factors, and pathogenic factors involved in the outbreak of foodborne diseases in this region are relatively routine and controllable. Therefore, efforts should be made to strengthen public food safety education to reduce the occurrence of foodborne diseases.

Objective To assess the clinical application value of axillary lymph node staging of breast cancer by B ultrasound.Methods From February to December 2014, 200 female breast disease patients in Department of Breast Surgery Affiliated Hospital of Academy of Military Medical Sciences, were enrolled, with median age 50 years old, including 153 cases of breast cancer, 44 cases of fibroadenoma, 2 cases of mastitis and a case of huge fibroma.The state of axillary lymph node was assessed by doctor with more than twenty years experience in B ultrasound diagnosis.According to the characteristics of the ultrasound image of lymph node and experience of the B ultrasound doctor, the patients were divided into axillary lymph node metastasis group, suspicious group and no metastasis group.The axillary lymph nodes were staged by sentinel lymph node biopsy or axillary lymph node dissection.Based on pathological diagnosis and results of the ultrasound, the sensitivity, specificity, positive predictive value, negative predictive value, false negative rate, and metastasis burden of axillary lymph nodes in false negative patients were analyzed.The relationship between the B ultrasound characteristics and axillary lymph node metastasis was also studied by univariate analysis.Results The metastasis rate of above-mentioned 3 groups by B ultrasound was 84.51%, 45.16% and 7.14%, respectively.The sensitivity, specificity, positive predictive value and negative predictive value of screening for axillary lymph node metastasis by B ultrasound were 89.6%, 89.1%, 84.5% and 92.7%, respectively in metastasis group and no metastasis group. According to consistency analysis between pathological diagnosis and B ultrasound, the Kappa value was 0.779.The false negative rate was only 7.1%(7/98 cases) in no metastasis group judged by B ultrasound, and the patients′axillary lymph node metastasis burden was very low, with only one lymph node positive.The univariate analysis showed that patients with longitudinal diameter of lymph nodes≥1 cm had a higher risk for metastasis than <1 cm (44.2%/14.3%,P<0.001);lymph node aspect ratio≤1.5, the lymph node metastasis rate was significant higher than>1.5(P<0.001); cortical thickness≥3 mm and lymph node appearing blood flow signal of the central or mixed type were also high metastasis risk factor, the lymph node metastasis rate was 67.5%, 75%and 79%, respectively, P<0.001).Conclusion B Ultrasound is a valuable method for detecting axillary lymph node metastasis in breast cancer.It has lower false negative rate, and the false negative patients just have smaller axillary lymph node metastasis burden.The longitudinal diameter of lymph nodes more than 1 cm, lymph node aspect ratio≤1.5, lymph node of cortical thickness≥3 mm, and blood flow signal of the central or mixed type have higher relationship with axillary lymph node metastasis.B Ultrasound may be a potential alterative method for sentinel axillary lymph node biopsy for axillary lymph node staging in early breast cancer.

Objective To evaluate the effect of the combined use of traditional Chinese medicine and lamivudine(LMD) in treating chronic hepatitis B patients, and to follow the serological response for six months or longer. Methods CNKI, Wanfang data, VIP data, CBMdisk, MEDLINE,EMBASE,BIOSIS and Cochrane Central Register of Controlled Trials database and literature were searched, to include randomized controlled trails (RCT) that used LMD alone or combined with traditional Chinese medicine. RevMan 4.2 was used for data analysis. Results The Meta analysis of 7 trails demonstrated that the HBeAg conversion rate in treatment group was higher than those from the control group, and the differences were statistically significant at 6, 9, 12 months. Conclusion Data demonstrated that early intervention of traditional Chinese medicine might increase the HBeAg conversion rate but conclusion needs to be more specific to the types of trials.

ghest. Conclusion In general, both the prevalence rates of overweight and obesity in Chinese minority students were comparatively low. However, in some minority groups the prevalence had already become higher, which demands early prevention.

myopia rates in 2005 were 29.5%, 39.1%, 10.1%, 42.6%, 41.1%, for boys and 45.4%, 50.0%, 15.4%, 49.7%, 46.7% for girls. Conclusion In order to improve the health of students in minority regions, we need to promote health education at schools.