Objective To demonstrate the feasibility, effectiveness and reliability of combination of procedure for prolapse and hemorrhoids (PPH) and excision-closed hemorrhoidectomy (ECH) for severe hemorrhoids. Methods Sixty patients with Ⅲ- Ⅳ degree hemorrhoids which left remnant prolapsed hemorrhoids after stapled hemorrhoidopexy, were randomly divided into group A (PPH with additional ECH group,30 cases.) and group B [PPH with additional Milligan-Morgan hemorrhoidectomy (MMH) group, 30 cases]. Ten indexes of the results in two groups were compared. ResultsThe hemorrhoidectomy lasted (35.6 ± 5.3) min in group A and (47.3 ± 10.2) min in group B. The indexes related to 24 h visual analogue scale (VAS) after operation were (2.9 ± 1.2) scores in group A and (5.7 ± 1.9) scores in group B. Wound healing time were (6.3 ± 1.4) d in group A and (28.5 ± 4.8) d in group B. Many indexes showed the results in group A was better than those in group B ( P ＜ 0.05 ). The six-month follow-up visits after operation showed no complications, such as recurrence in either group. ConclusionsCombination treatment for Ⅲ -Ⅳ degree hemorrhoids with PPH with additional ECH is a easy,safe,reliable,minimal-aching and quick-recovering method of hemorrhoidectomy with favorable results than PPH with additional MMH.

Objective To determine the content of calycosin-7-?-O-D-glucopyranpside in Danggui Buxie Dropping Pills.Methods HPLC method was used. The chromatographic column was YMC-C18(150?4.6 mm, 5 ?m), the mobile phase was methanol and water(40 ∶60), the detection wavelenth was 235 nm, column temperature at 20 ℃and flow rate was 1.0mL/min.Results Calycosin-7-?-O-D-glucopyranpside was separated well with other components and was in good linearity in the range of 0.02～0.80 ?g. The average recovery was 97.62 %and RSD=1.06 %.Conclusion The method is rapid and accurate and can be used for quality control of Danggui Buxie Dropping Pills.

Hydrocarbons, Brominated ; metabolism ; toxicity ; Occupational Exposure

BACKGROUND:Nano-hydroxyapatite/collagen (NHAC) is an ideal substitute for tissue engineered stent. Vascular endothelial growth factor (VEGF) is a kind of growth factor that can promote vascularization and slowly release NHAC. This indicated a good bone tissue repair function. OBJECTIVE:To investigate the effect of NHAC combined with VEGF in repairing bone defects. DESIGN,TIME AND SETTING:The randomized controlled animal study was performed at the Animal Laboratory,Xiangya Medical College,Central South University from October 2008 to January 2009. MATERIALS:Nano-hydroxyapatite powder and collagen protein powder were mixed and prepared into NHAC artificial bone according to the ratio of 8:2. 2 ?g of VEGF and NHAC were mixed and prepared into NHAC/VEGF artificial bone according to the ratio of 1.8:1. Each artificial bone contained 0.5 g nano-hydroxyapatite powder,0.125 g collagen protein and 150 ng VEGF. METHODS:Thirty-six healthy rabbits whose left radiuses were cut off 1 cm were divided into three groups. The wounds of the rabbits in blank group were sewed up directly without any treatment of the bone. The bone defects of the rabbits in NHAC group were repaired with NHAC artificial bones and the NHAC/VEGF group with NHAC/VEGF artificial bones. MAIN OUTCOME MEASURES:After 2,4 and 8 weeks,4 rabbits in each group were killed to evaluate whether they have significant differences of bone healing according to general observation,radiograph,pathological section and bone density test. RESULTS:Radiograph showed that osteotylus growth and the repairing of bone defects in the NHAC/VEGF group were better than in the blank group and NHAC group. It was better in the NHAC group than in the blank group. The difference in bone density of two groups in the same time was significant (P

Objective To evaluate the efficiency of nutrition support in critical ill patients. Methods A retrospective analysis was made to the efficiency of the nutrition support applied to 233 critical ill patients PN+EEN→EN+per os→per os was employed as the model of nutrition support, and a nasal feeding pump was used for enteral nutrition. Results During the period of nutrition support, in the 233 patients, 26 dead, the mortality was 11.16%. Early enteral nutrition significantly decrease the mortality in critical ill patients. There existed significant differences in complications in three kinds of enteral nutrition may methods. Conclusion It is feasible to give the critical ill patients, it might help to reduced the mortality in ICU patients.

Hyperlipidemia is a major risk factor for the generation and development of atherosclerosis and coronary heart disease. The lipid-lowering effects of drugs were mediated by the control of lipid metabolism.Recently some new targets in the process of lipid metabolism were found,they may lead to the development of new drugs.

Objective To improve the diagnosis of metastatic adrenal carcinomas. Methods 123 cases of primary canc-er which had been proved by autopsy in recent 10 years were reviewed. 23 cases of metastatic adrenal carcinomas werefound in all cases,the metastatic being unilateral in 20 and bilateral in 3. Results All the 23 cases of metastatic adrenal-carcinomas had been found missed diagnosis. Conclusion 16 cases are from lung cancer,among which 8 cases are smallcell lung cancer. It is important to prevent metastatic adrenal carcinomas from small cell lung cancer.

By one trial passive avoidance respense-step-down task and water maze spatial localizat　ion task, the effect of Ginseng and Angelica Sinensis Decotion (GASD)on pathological mod　els of the anmesia rat with hippocampal lesions induced by quiuolinic acid was studied. Re　sults suggest that GASD can improve learning aud memory deficiency in rats with bilateral hippocampal lesions after administration of quinolinic acid. The major mechanism of GASD may be related to the regulation of the glutamatergic fuuction and prevention of the neuro　toxicity of quinolinic acid

Objective To understand the current status of blood pressure and to analyze its influence factors in rural residents in Tianjin.Methods Total 2 390 754 rural residents aged over 15 yrs were detected on their blood pressure by the trained professional staffs with standard method,then calculated the mean of blood pressure and hypertension prevalent rate,compared with results of Village I of National Nutrition and Health Situation Investigation in 2002.After population standardized,a multivariate analysis was done on hypertension in subjects.Results The average SBP was(125.91?18.99)mm Hg,average DBP was(80.44?10.77)mm Hg;hypertension prevalent rate was 31.57%(33.08% for male and 30.18% for female).The general hypertension prevalence was higher than that of the national level;after standardized with China population in 2000,the prevalent rate of hypertension in the group aged over 18 yrs was nearly 50% higher than that in national level.The multivariate analysis showed that the affected factors for hypertension of rural residents included age,gender,region,education level,smoking,alcohol drinking and obesity.Conclusions Hypertension had become a popular and serious public health problem.To prevent and control hypertension should be one of the key issues of chronic diseases prevention in rural area.

OBJECTIVE:To explore the ward round model of clinical pharmacists.METHODS:The ward round model of clinical pharmacists was designed and explored based on clinical practice.RESULTS & CONCLUSION:Clinical pharmacists can engage in ward rounds either in cooperation with physicians or alone in special department,or by targeting at those patients using certain drugs.Each model has its distinctive characteristics and clinical pharmacists can choose suitable model based on their own level as well as the conditions in software,hardware and environment so as to facilitate rational administration.