No abstract available.

No abstract available.
Chronic Disease ; Glycemic Index

Chloroma is an unusual presenting feature of acute leukemia in childhood. These are found in relation to the periosteum of the skull, paranasal sinuses, orbits, vertebrae or ribs. Chloromas may occasionally produce central or peripheral neurologic disturbance, as this patient demonstrated. 9 year old girl entered this hospital with complaints of protrusion of left eye, headache and vomiting. A month prior to admission the parent noted slight protrusion of left eye which had progressed rapidly with development of another small mass in the scalp. On admission, the patient showed rather anemic somewhat dull mentality and moderate papilledema on right. Blood picture and biopsy of scalp mass revealed hematologic and cytologic features of leukemia. The girl has deteriorated rapidly and died on the 28th hospital day. Autopsy showed multiple chloromas in relation to the periosteum of orbital fossa, ribs, pelvis, and skull. There were four masses as large as one to two cm in diameter at the inner aspect of dura mata which were compressing the brain. It is rare in this country that the infiltration of chloroma on the dura mata was proved in autopsy.
Autopsy ; Biopsy ; Brain ; Child ; Female ; Headache ; Humans ; Leukemia ; Orbit ; Papilledema ; Paranasal Sinuses ; Parents ; Pelvis ; Periosteum ; Ribs ; Sarcoma, Myeloid ; Scalp ; Skull ; Spine ; Vomiting

Chloroma is an unusual presenting feature of acute leukemia in childhood. These are found in relation to the periosteum of the skull, paranasal sinuses, orbits, vertebrae or ribs. Chloromas may occasionally produce central or peripheral neurologic disturbance, as this patient demonstrated. 9 year old girl entered this hospital with complaints of protrusion of left eye, headache and vomiting. A month prior to admission the parent noted slight protrusion of left eye which had progressed rapidly with development of another small mass in the scalp. On admission, the patient showed rather anemic somewhat dull mentality and moderate papilledema on right. Blood picture and biopsy of scalp mass revealed hematologic and cytologic features of leukemia. The girl has deteriorated rapidly and died on the 28th hospital day. Autopsy showed multiple chloromas in relation to the periosteum of orbital fossa, ribs, pelvis, and skull. There were four masses as large as one to two cm in diameter at the inner aspect of dura mata which were compressing the brain. It is rare in this country that the infiltration of chloroma on the dura mata was proved in autopsy.
Autopsy ; Biopsy ; Brain ; Child ; Female ; Headache ; Humans ; Leukemia ; Orbit ; Papilledema ; Paranasal Sinuses ; Parents ; Pelvis ; Periosteum ; Ribs ; Sarcoma, Myeloid ; Scalp ; Skull ; Spine ; Vomiting

No abstract available.
Bone Marrow* ; Iron* ; Microwaves* ; Plastics*

No abstract available.
Humans ; Hypersensitivity* ; Skin*

No abstract available.

No abstract available.
Bone Marrow* ; Microwaves* ; Plastics*

BACKGROUNDS: It is well known that intimal hyperplasia is one of the most important cause of vascular graft failure in angioplasty, autogenous venous graft and prosthetic bypass graft. Clinical trials of drugs including antiplatelet agents, anticoagulant, corticosteroid, cyclosporine and prostaglandin were not satisfactory in suppressing intimal hyperplasia. Seeding of endothelial cell also have been done for this purpose with some success. There are several reports that endovascular low dose irradiation and external beam irradiation might reduce the amount of proliferative neointima after arterial injury. METHODS: In order to evaluate the effect of external beam irradiation on intimal hyperplasia in grafted vessel, femoral artery autografts using external jugular vein were performed in dogs, and studied the morphological finding under microscope and compared intimal hyperplasia between control and radiated groups. Group I (control) was not irradiated after graft. But experimental groups were irradiated with 6 Mev electron: Group II, 800 cGy on day 1; Group III, 400 cGy on day 1 and day 4 each; and Group IV, 800 cGy on day 4. Radiation efficacy on intimal hyperplasia was histologically assessed by measuring neointimal thickness at the proximal and distal site of grafted vessel at 6 weeks after graft. RESULTS: Mean neointimal thickness in all irradiated groups were significantly lesser than control group (p<0.05) and not related with irradiating time: Group I (Control), 0.41+/-0.11 mm; Group II, 0.16+/-0.10 mm; Group III, 0.19 0.10 mm; Group IV 0.15+/-0.08 mm. There was no difference in intimal hyperplasia between proximal and distal anastomotic site of grafted vessels in both control and irradiated groups: Control, 0.42+/-0.11 mm vs 0.40+/-0.10 mm; Radiated groups, 0.17+/-0.10 mm vs 0.16+/-0.09 mm; (p>0.05). CONCLUSION: These data suggest that low dose external beam irradiation might suppress intimal hyperplasia in grafted vessel, but further study will be necessary to determine optimal dose and timing of radiation delivery, and its efficacy in long segment bypass graft.
Angioplasty ; Animals ; Autografts* ; Cyclosporine ; Dogs* ; Endothelial Cells ; Femoral Artery* ; Hyperplasia* ; Jugular Veins ; Neointima ; Platelet Aggregation Inhibitors ; Transplants

Purpose: This study attempted to obtain basic data for developing a global nursing practice education program. Methods: The data collection period was from July 2 to 11, 2020. The study participants were professors with experience in design, operation and management of global nursing practice education or experts with experience in international cooperation projects, and 8 people who agreed to participate in focus group interview (FGI). FGI was conducted twice in total and the directed content analysis method was applied. Results: The categories of ‘practice design’ are ‘growing as a global nursing leader’ and ‘working together towards one goal’. The categories of ‘practice operation’ are ‘watching, listening, and performing’, ‘self-directed organizing from preparation to finishing’, and ‘learning the value of participation rather than grades’. The category of 'practice management' is 'one's own weight to carry'. Conclusion Global nursing practice education aims one goal - growing as a global nursing leader - and is self-directed course from preparation to an end with watching, listening and performing together. It is about learning the value of participation rather than grades. This can be used as basic data for the design, operation and management of global nursing practice education in the future.