In order to have a better understanding of the relation between vertical dimension and occlusal force,a meter was made by means of straingauge.Five Japanese men were investi- gated for occlusal force at different vertical dimensions.The measurements showed that the maximal occlusal force of the posterior teeth occured at 8 to 15mm or the vertical dimension, the maximal occlusal forec of the anterior teeth occured at 13 to 18mm.This indicated that the occlusal force was closely related to the state of jaw closing muscle.

OBJECTIVE:To provide suggestions for the setting-up of the current pharmacovigilance(PV)system.METHODS:The characteristics of the setup of the PV system in both US and France were analyzed and the problems encountered in current monitoring system of adverse drug effects were pointed out.RESULTS & CONCLUSION:Both American and French PV systems have their own advantages and we should learn from it and draw useful experiences from them.In constructing PV system,China should make improvement in organization,communication,financial resource and information technology etc.

The concrete methods and experiences for foreign students in case study in the past decades were introduced in this article. We emphasized on teaching students in accordance with their aptitude and step by step, explaining the profound things in a simple way and giving attention to different students' capabilities during teaching. In the practice, we surely felt that case study will bring more advantage than traditional teaching methods, motivate students and improve the capabilities to understand the course content.

Inflammatory reaction plays an important role in the occurrence and development of ischemic stroke. Monocyte chemotactic protein-1 (MCP-1) is one of the subfamily members of the CC chemokine class. It can attract and activate a variety of cells, such as monocytes and T lymphocytes, promote the expression of cytokines, and participate in the occurrence of ischemic brain injury. This article reviews the progresses on the MCP-1 and ischemic stroke-related research.

Animals ; Blood Glucose ; Cucurbita ; chemistry ; Diabetes Mellitus, Experimental ; drug therapy ; Hypoglycemic Agents ; pharmacology ; Lipids ; blood ; Oxidative Stress ; Polysaccharides ; pharmacology ; Rats

Objective To test the reliability and validity of the collective self-esteem scale for freshman.Methods 800 freshmen finished the Collective Self-Esteem Scale,the Life Satisfaction Scale,and Self-esteem Scale.Results The confirmatory factor analysis shows that collective esteem includes membership esteem,private collective esteem,public collective esteem,and importance to identiy intemal consistency a of the scale and the 4 components of the scale ale between0.6357and 0.8369.All components of the scale except importance to identity have significantly positive correlation with life satisfaction and self-esteem.(0.14＜r＜0.41,P＜0.01).Gids have more scores than boys in total collective esteem(t=3.38,P＜0.01),Private CSE and Importance to Identity (t=3.32,P＜0.01).Conclusion The revised collective self-esteem scale for freshmen has sound reliability and validity.It is a good instrument for measuring collective self-esteem of Chinese freshman.

Objective:To investigate the intervention effect of vitamin C for the treatment to diabetes patients with diabetes and gastric ulcer.Methods: 53 cases of patients with diabetes combined with gastric ulcer were selected as the research subjects, and were divided into a control group(23) and a intervention group(30). The patients in two groups were given the treatment of reducing blood sugar and anti-HP triple therapy. The intervention group was given additionally diet intervention via eating vitamin C. The blood sugar, blood lipid levels, gastric ulcer index and inflammatory markers of the two groups were reviewed six months later by helicobacter pylori type detector. And the statistical analysis was performed.Results: After treatment, the blood sugar, blood lipid levels, gastric ulcer index and inflammatory markers of the two groups were significantly improved (t=1.23,t=1.35,t=2.63,t=1.07,t=0.77,P<0.05), except for the HP cure rate (P>0.05). Other indexes of the intervention group are significantly better than the control group (t=1.45,t=1.67,t=2.33, t=1.55,P<0.05).Conclusion:Vitamin C play a very good role in the treatment and prevention for the blood sugar, the blood lipids, gastric function and inflammation of patients with diabetes and gastric ulcer, and helicobacter pylori type detector can simplify the detection of helicobacter pylori.

Mycoplasma pneumoniae(MP) is the smallest organism that dose not need a host cell for replication.It is one of the most common pathogens of community acquired pneumonia in children.In recent years,the incidence of pneumonia mycoplasma pneumonia increased year by year,and severe pneumonia mycoplasma pneumonia,refractory pneumonia mycoplasma pneumonia cases also increased.MP causes a variety of clinical presentations,in addition to respiratory infections,there are also many extrapulmonary manifestations.Immune response plays a very important part in pathogenesis of MP infection.This article focused on the immune aspects in pathogenesis and extends to some diagnosis and therapeutic implications.

Objective To investigate the effects of the EGF on isolation and cloning of mouse embryonic stem-like cells from PGCs. Methods EGF with different density were added to the culture medium of cells .After a culturing period ,the cloning number of mouse embryonic stem-like cells and the topmost passage would be observed and registered. Results There was not obvious effects on the primary culture of mouse ESC and was distinct on the later passage if EGF were used. Conclusions In the primary passage of mouse ESC may survive without EGF,and the impact of the existence of EGF was better than the one of the inexistence to the cloning of mouse ESC.

Objective To evaluation the Diagnosis value of single and consociation to drawing materials methods with bronchofibroscopy in pulmonary carcinoma.Methods 481 diagnosed patients with pulmonary carcinoma by bronchofibroscopy during July 2000 to July 2006 were analyzed.Four different drawing materials method including clamping,brushing,needling and rinse checking were used to diagnose.The positive rates of these four methods were compared with single and consociation to drawing materials methods.Results The positive rate of clamping,brushing,needling and rinse checking were 83.9%,70%,59.1%and 35.9%respectively,and the total positive rate was 90.2%after being united.Conclusions Bronchofibroscopy is one of the most important methods in diagnosing pulmonary carcinoma. Using multiple drawing materials methods in bronchofibroscopy can improve the accuracy rate of diagnosis of lung cancer significantly.