No abstract available.
Animals ; Cauda Equina* ; Dogs*

Small bowel capsule endoscopy (CE) was first introduced 15 years ago, and a large amount of literature has since been produced, focused on its indication, diagnostic yields, and safety. Guidelines that have made CE the primary diagnostic tool for small bowel disease have been created. Since its initial use in the small bowel, CE has been used for the esophagus, stomach, and colon. The primary indications for small bowel CE are obscure gastrointestinal bleeding, unexplained iron deficiency anemia, suspected Crohn's disease, small bowel tumors, nonsteroidal anti-inflammatory drug enteropathy, portal hypertensive enteropathy, celiac disease, etc. Colon CE provides an alternative to conventional colonoscopy, with possible use in colorectal cancer screening. Guidelines for optimal bowel preparation of CE have been suggested. The main challenges in CE are the development of new devices with the ability to provide therapy, air inflation for better visualization of the small bowel, biopsy sampling systems attached to the capsule, and the possibility of guiding and moving the capsule by an external motion controller. We review the current status and future directions of CE, and address all aspects of clinical practice, including the role of CE and long-term clinical outcomes.
Anemia, Iron-Deficiency ; Biopsy ; Capsule Endoscopy* ; Celiac Disease ; Colon ; Colonoscopy ; Colorectal Neoplasms ; Crohn Disease ; Esophagus ; Hemorrhage ; Inflation, Economic ; Intestine, Small ; Mass Screening ; Stomach

This report concerns a rare malignant smooth muscle neoplasm of the skin and the subcutaneous tissue, which was examined immunohistochemically and ultrastructurally. It occured in a 48-year-old female patient who had suffered from painful nodules on the left shoulder. The nodules were removed and diagnosed as a benign fibrohistiocytic tumor. One year after local excision, multiple nodules were detected by physical examination at the previous operation site. Grossly, thirteen well-defined small nodules had spread in the dermis and the subcutaneous tissue, of which nine were located from lower dermis to the subcutaneous tissue and four were in the subcutaneous tissue. Histologically, each nodule consisted mainly of epithelioid tumor cells having eosinophilic or clear plump cytoplasm and round to oval nuclei with small nucleoli, and some peripheral spindle tumor cells. The tumor cells were negative for PAS reaction with and without diastase digestion or alcian blue. Immunohistochemically, tumor cells were positive for smooth muscle actin and vimentin. Ultrastructurally, the tumor cells showed actin filaments and dense bodies in cytoplasm. This case was diagnosed as an epithelioid leiomyosarcoma of the skin and the subcutaneous tissue with local metastasis one year after local excision.
Actin Cytoskeleton ; Actins ; Alcian Blue ; Amylases ; Cytoplasm ; Dermis ; Digestion ; Eosinophils ; Female ; Humans ; Leiomyosarcoma* ; Middle Aged ; Muscle, Smooth ; Neoplasm Metastasis ; Periodic Acid-Schiff Reaction ; Physical Examination ; Shoulder ; Skin* ; Subcutaneous Tissue ; Vimentin

No abstract available.
Thanatophoric Dysplasia*

Retinal detachment is a rare and unusual complication of preeclampsia. In 6,194 consecutive deliveries from January 1987 to July 1990 at the Soonchunhuang University Hospital, pregnancy induced hypertension was diagnosed in 223 patients(3.6%), and in 11 cases serous retinal detachment occured. We studied retrospectively the incidence, clinical characteristics and pathophysiology of the retinal detachment in the pregnany induced hypertension. The results were as follows: 1. Retinal detachment was serous type and mostly bilateral(90.9%). 2. Retinal detchment occured principally in primigravid(63.64%). 3. Serotts retinal detachment occured in 11 cases in 6,194 consecutive diliveries(0.18%) with 9 cases in 211 preeclampsia(4.27%) and 2 cases in 12 eclampsia(17.67%). 4. Reattachment of the retina occured at an interval of 7 to 29 days with an average interval of 14 days after delivery. 5. The fluorescein angiographic findings provide clinical evidence that retinal detachment in pregnancy induced hypertension is secondary to choroidal damage.
Choroid ; Female ; Fluorescein ; Hypertension ; Hypertension, Pregnancy-Induced ; Incidence ; Pre-Eclampsia ; Pregnancy* ; Retina ; Retinal Detachment* ; Retinaldehyde* ; Retrospective Studies

Retinal detachment is a rare and unusual complication of preeclampsia. In 6,194 consecutive deliveries from January 1987 to July 1990 at the Soonchunhuang University Hospital, pregnancy induced hypertension was diagnosed in 223 patients(3.6%), and in 11 cases serous retinal detachment occured. We studied retrospectively the incidence, clinical characteristics and pathophysiology of the retinal detachment in the pregnany induced hypertension. The results were as follows: 1. Retinal detachment was serous type and mostly bilateral(90.9%). 2. Retinal detchment occured principally in primigravid(63.64%). 3. Serotts retinal detachment occured in 11 cases in 6,194 consecutive diliveries(0.18%) with 9 cases in 211 preeclampsia(4.27%) and 2 cases in 12 eclampsia(17.67%). 4. Reattachment of the retina occured at an interval of 7 to 29 days with an average interval of 14 days after delivery. 5. The fluorescein angiographic findings provide clinical evidence that retinal detachment in pregnancy induced hypertension is secondary to choroidal damage.
Choroid ; Female ; Fluorescein ; Hypertension ; Hypertension, Pregnancy-Induced ; Incidence ; Pre-Eclampsia ; Pregnancy* ; Retina ; Retinal Detachment* ; Retinaldehyde* ; Retrospective Studies

No abstract available.
Capsule Endoscopy*

No abstract available.
Capsule Endoscopy*

Plexiform schwannoma is a relatively rare, benign peripheral nerve sheath tumor that can be located either in the deep soft tissues or in the dermis or subcutaneous tissue. This tumor may occur singly or as multiple lesions and may be localized to one anatomic site or diffusely distributed. Plexiform schwannoma should be differentiated with plexiform neurofibroma or other plexiform malignant tumors. We describe a case of a 6-year-old patient with multiple cutaneous plexiform schwannomas who had no other stigmata of neurofibromatosis 1 or family history suggesting a genetic disorder. The histopathological study revealed a tumor composed of multiple intradermal or subcutaneous interlacing and interconnecting fascicles and nodules that vary in size and shape. Characteristic Antoni A type cellular tissue showing frequent nuclear palisading and Verocay bodies were observed within well circumscribed elongated nodules.
Child ; Christianity ; Dermis ; Humans ; Neurilemmoma* ; Neurofibroma, Plexiform ; Neurofibromatosis 1 ; Peripheral Nerves ; Subcutaneous Tissue

We report a case of cutis verticis gyrata-mental deficiency syndrome associated with generalized epidermal nevus. The clinical features of the patient included severe mental retardation, drug resistant epilepsy, short stature, scaphocephaly and dysmorphic face with scanty scalp hair, hypertelorism, long palpebral fissure, low nasal bridge, hyperplasia of ala nasi, low-set ears with convoluted fold, and partial obstruction of the nasolacrimal ducts. Multiple convoluted folds and furrows on the scalp were extended to eyebrows and nose. Both lateral ventricle with periventricular leukomalacia were dilated markedly and the corpus callosum was hypoplastic on brain MRI. The nature of the yellowish brown colored elevated skin nevi on the whole body was consistent with systemic epidermal nevus by pathological study.
Brain ; Corpus Callosum ; Craniosynostoses ; Ear ; Epilepsy ; Eyebrows ; Hair ; Humans ; Hyperplasia ; Hypertelorism ; Infant, Newborn ; Intellectual Disability ; Lateral Ventricles ; Leukomalacia, Periventricular ; Magnetic Resonance Imaging ; Nasolacrimal Duct ; Nevus* ; Nose ; Scalp ; Skin