1.The purpose of methtrexate saturation test in chemotherapy of gestational trophoblastic disease.
Won Young CHOI ; Woong Shick AHN ; Jae Keun JUNG ; Seung Kyu SONG ; Hun Young LEE ; Seung Jo KIM
Korean Journal of Obstetrics and Gynecology 1991;34(7):992-998
No abstract available.
Drug Therapy*
;
Gestational Trophoblastic Disease*
2.Postoperative Radiological Changes in Chronic Subdural Hematoma and Its Relation to Recurrence.
Hyon Jo KWON ; Jin Young YOUM ; Seon Hwan KIM ; Hyeon Song KOH ; Shi Hun SONG ; Youn KIM
Journal of Korean Neurosurgical Society 2004;35(4):410-414
OBJECTIVE: The authors analyzed the postoperative radiological changes in chronic subdural hematoma (CSDH) after operation and its relation to the recurrence. METHODS: After reviewing the postoperative imagings of CSDH patients (90 cases, 70 patients), we classified them into 4 types according to the radiological changes in the hematoma area and calculated the prevalence of recurrence respectively. We also reviewed the preoperative images of the same patients and classified them into 4 types according to hematoma density and internal structure and investigated the prevalence of recurrence after operation respectively. RESULTS: The low density area in postoperative computerized tomography (CT) showed the same Hounsfield unit and signal intensity in magnetic resonance imaging (MRI) with the CSF in ventricles. The recurrence of CSDH was lower if the hematoma was totally replaced with CSF (Type III) or the brain re-expanded completely with total hematoma drainage (Type IV) on postoperative imagings (p<0.05). The location of catheter tip can be used as a valuable indicator of the boundary of newly collected CSF and residual hematoma. CONCLUSION: The low-density area found on postoperative CT medial to the residual hematoma in CSDH is filled with CSF and it can be a helpful factor in reducing the recurrence. The catheter tip location can be used as a good index and we can remove the catheter immediately after confirming the tip location on the inner surface of the skull.
Brain
;
Catheters
;
Drainage
;
Hematoma
;
Hematoma, Subdural, Chronic*
;
Humans
;
Magnetic Resonance Imaging
;
Prevalence
;
Recurrence*
;
Skull
3.Pleomorphic Xanthoastrocytoma: Report of Three Cases.
Young Jo CHA ; Seong Ho KIM ; Shi Hun SONG ; Kwan Tae KIM ; Kyu Sang SONG ; Youn KIM
Journal of Korean Neurosurgical Society 1993;22(12):1387-1393
Pleomorphic xanthoastrocytoma is known as a rare specialized type of cerebral astrocytoma, which occurs mainly in the temporal loe of the brain in young ages in spite of marked pleomorphism with multinucleated giant cells, lipid-laden xantomatous cells, rich reticulin net-works, and the demonstration of glial fibrillary acidic protein, the prognosis is usually favorable. The authors report three cases of pleomorphic xanthoastrocytoma which were presented with headache and review the past literature.
Astrocytoma
;
Brain
;
Giant Cells
;
Glial Fibrillary Acidic Protein
;
Headache
;
Prognosis
;
Reticulin
4.Intraventricular Hemorrhage due to Aneurysm of the Distal Posterior Inferior Cerebellar Artery: Case Report.
Young Jo CHA ; Seong Ho KIM ; Shi Hun SONG ; Kwan Tae KIM ; Youn KIM
Journal of Korean Neurosurgical Society 1992;21(9):1192-1197
A case of ruptured aneurysm of the distal PICA presenting with isolated intraventricular hemorrhage is presented. The diagnosis of distal PICA aneurysm should be considered if isolated intraventricular hematoma is found without obvious parenchymal hemorrhage or subarachnoid blood in the basal cisterns. Complete vertebral arteriography is a requiste for the recognition of this condition. The outcome in patients with these aneurysms should be good if surgical repair is performed before rebleeding occurs.
Aneurysm*
;
Aneurysm, Ruptured
;
Angiography
;
Arteries*
;
Diagnosis
;
Hematoma
;
Hemorrhage*
;
Humans
;
Pica
5.A Case of Hypertension Secondary to Paraganglioma of the Posterior Mediastinum..
Eui Kyeong HWANG ; Jae Woong CHOI ; In Hu HWANG ; Chan Hee MUN ; Hyun Jo MIN ; Chang Sup SONG ; Choong Hun SUH ; Eun Ju KO ; Eun Kyeong KIM
Korean Circulation Journal 1997;27(8):895-899
Functional paraganglioma of the mediastinum is an uncommon tumor of the paraganglion system that causes symptoms and signs of episodic catecholamine release. It has not been reported in Korea. We experienced a case of a 17 years old man with a history of diaphoresis and paroxysmal hypertension refractory to therapy since 14 years old. Urinary execretion of catecholamine and its metabolites were elevated. Computed tomography(CT) scan revealed high density mass located on the posterior mediastinum in the area of the right fifth intercostal space. At thoracotomy, a 3X3X4cm sized lesion was resected and confirmed as a paraganglioma.
Adolescent
;
Humans
;
Hypertension*
;
Korea
;
Mediastinum*
;
Paraganglioma*
;
Pheochromocytoma
;
Thoracotomy
6.Genetic classification of hydatidiform mole using restriction fragment length polymorphisms(RFLPs).
Jong Chul SONG ; Eung Jung BAIK ; Woo Ik SON ; Ki Sung YOO ; Joon Mo LEE ; Jae Keun JUNG ; Seung Jo KIM ; Hun Young LEE
Journal of the Korean Cancer Association 1993;25(4):556-562
No abstract available.
Classification*
;
Female
;
Hydatidiform Mole*
;
Pregnancy
7.Aneurysmal Bone Cyst of the Second Cervical Spine.
Sung Hun CHA ; Geun Sung SONG ; Dong June PARK ; Byoung Jo JANG ; Young Woo LEE
Journal of Korean Neurosurgical Society 1995;24(1):84-90
Aneurysmal bone cysts are lytic lesions that have been described in virtually every portion of the skeleton but most commonly occur as solitary lesions in the metaphyseal portions of long bones. One fifth of aneurysmal bone cysts occur in the spine where they most frequently involve the posterior elements. In the spine, aneurysmal bone cyst have been reported to occur in the lower thoracic and lumbar regions, but their occurrence in the cervicodorsal area is uncommon. In this case, the second cervical vertebral body and posterior elements are affected. Fortunately, the lesion didn't invade into the spinal canal. The main symptom on admission was pressure pain, tenderness and motion limitation of the cervical spine. We removed the lesion involving posterior elements of second cervical spine and used horse-shoe shaped pediatric C-D device for occipito-cervical fixation. The clinical symptoms were resolved after operation. The clinical, radiologic, operative and pathological findings are reported and the corresponding literature are reviewed.
Aneurysm*
;
Bone Cysts*
;
Bone Cysts, Aneurysmal
;
Lumbosacral Region
;
Skeleton
;
Spinal Canal
;
Spine*
8.Mortality and Epidemiology in 256 Cases of Pediatric Traumatic Brain Injury: Korean Neuro-Trauma Data Bank System (KNTDBS) 2010–2014.
Hee Won JEONG ; Seung Won CHOI ; Jin Young YOUM ; Jeong Wook LIM ; Hyon Jo KWON ; Shi Hun SONG
Journal of Korean Neurosurgical Society 2017;60(6):710-716
OBJECTIVE: Among pediatric injury, brain injury is a leading cause of death and disability. To improve outcomes, many developed countries built neurotrauma databank (NTDB) system but there was not established nationwide coverage NTDB until 2009 and there have been few studies on pediatric traumatic head injury (THI) patients in Korea. Therefore, we analyzed epidemiology and outcome from the big data of pediatric THI. METHODS: We collected data on pediatric patients from 23 university hospitals including 9 regional trauma centers from 2010 to 2014 and analyzed their clinical factors (sex, age, initial Glasgow coma scale, cause and mechanism of head injury, presence of surgery). RESULTS: Among all the 2617 THI patients, total number of pediatric patients was 256. The average age of the subjects was 9.07 (standard deviation±6.3) years old. The male-to female ratio was 1.87 to 1 and male dominance increases with age. The most common cause for trauma were falls and traffic accidents. Age (p=0.007), surgery (p<0.001), mechanism of trauma (p=0.016), subdural hemorrhage (SDH) (p<0.001), diffuse axonal injury (DAI) (p<0.001) were statistically significant associated with severe brain injury. CONCLUSION: Falls were the most common cause of trauma, and age, surgery, mechanism of trauma, SDH, DAI increased with injury severity. There is a critical need for effective fall and traffic accidents prevention strategies for children, and we should give attention to these predicting factors for more effective care.
Accidental Falls
;
Accidents, Traffic
;
Brain Injuries*
;
Cause of Death
;
Child
;
Craniocerebral Trauma
;
Developed Countries
;
Diffuse Axonal Injury
;
Epidemiology*
;
Female
;
Glasgow Coma Scale
;
Hematoma, Subdural
;
Hospitals, University
;
Humans
;
Korea
;
Male
;
Mortality*
;
Pediatrics
;
Republic of Korea
;
Trauma Centers
9.Experimental Trial for the Prevention of Adhesion with Dural Substitutes in Craniectomy State.
Young Jo CHA ; Si Hun SONG ; Seong Ho KIM ; Kwan Tae KIM ; Youn KIM
Journal of Korean Neurosurgical Society 1993;22(11):1167-1174
In a series of rabbits, two craniectomies were made in both side of the parietal hone. Each lesion was filled with gelfoam, lyocura, fat and dural film. Five rabbits were left empty as a control group. The animals were killed in one month after the operation. The degree of adhesion between the soft tissue of the scalp and various dural substitute was evaluated at the time of operative dissection and studied histopathologically. The results were as follows. 1) The insertion of dural substituted substances can prevent the adhesion between the scalp and dura mater. 2) The dural film was most effective in prevention of adhesion. 3) The dural film inserted group exhibited inflammatory reaction. 4) The gelfoam, lyodura and fat inserted groups were though to have had a moderate prevention effect of adhesion. With these results, we could conclude that the insertion of material between the dura and scalp can prevent adhesion. However the ideal inserted material which can pevent inflammatory reaction and adhesion has not been determined. At this point we have not found and ideal substitute. To get an ideal material for prevention of adhesion, further intensive study is required.
Animals
;
Dura Mater
;
Gelatin Sponge, Absorbable
;
Rabbits
;
Rabeprazole
;
Scalp
10.A Clinical and Histopathologic Study of Ovarian Hemorrhagic Lesions.
Myeong Chan KIM ; Sang Bum HA ; Yong Suk CHOI ; Jong Oh KIM ; Seong Lim LEE ; Hun Kyung LEE ; Seung Kyu SONG ; Bong Choon JO
Korean Journal of Obstetrics and Gynecology 2000;43(10):1731-1737
No abstract available.