Chinese genuine regional herbs are a combination of nature resource and traditional knowledge. Although we can make it to be an intellectual property product through applying geographical indication or certification mark, the value realization of Chinese genuine regional herbs should be supported by the merchant capital. Meanwhile, the merchant capital also disturbs the reasonable market price of Chinese genuine regional herbs. We should combine the merchant capital with Chinese genuine regional herbs, apply permission for sale and set up a new professional cooperation mode to maintain the market credibility and reasonable price of Chinese genuine regional herbs.

Postprandial hyperglycemia is one of the characteristics of glucose profiles in Chinese T2DM patients. High-ratio premix insulin analogues with advantages of excellent pharmacokinetic characteristics and flexible and convenient administration provide a comprehensive solution for Chinese T2DM patients to effectively control postprandial glucose and reduce blood glucose fluctuation. This paper is a literature review on its clinical evidence and experience.

Atopic dermatitis is a common chronic recurrent atopic constitution-associated inflammatory skin disease mainly characterized by eczematous lesions and itching. Its etiology and pathogenesis are still not very clear, and there are many controversies about its origin, definition, clinical phenotypes and diagnostic criteria. This review analyzes and discusses these controversies in order to provide a meaningful reference for the diagnosis and treatment of atopic dermatitis.

No abstract available.
Animals ; Embryo Implantation* ; Embryonic Structures* ; Female ; Mice* ; Pregnancy

No absteact available.
Resuscitation*

No abstract available.
Agglutination* ; Alisma* ; Animals ; Erythrocytes* ; Mice* ; Plantago*

Objective　To observe the germicidal efficacy and stability of the telephone disinfection mat that based on mic-capsule of 2% po tentiated glutaraldehyde in laboratory. Methods　The experiment was carried out according to the criteira of disinfection microbiology in labora tory issued by the Ministry of Health of the country in 1999. Results　 The bactericidal efficiency reached 99.99% for Escherichia coli,St aphylococcus aureus and Candida albicans when soaked in 2% potentiated glu taraldehyde for 3 to 5 min and the HBsAg can be destroyed when soaked for 10 min. Conclusion　The JM-high efficiency telephone disinfection mat is of good bactericidal and stable.

Objective:To analyze the clinical value on fetal heart monitor combined with umbilical artery S/D monitoring and forecasting fetal distress.Methods: A total of 280 cases in our hospital hospitalized were given maternal heart monitor combined with umbilical artery S/D monitoring. According to the test results, they were divided into normal group with 158 cases, abnormal fetal heart rate group with 21 cases, abnormal S/D value group with 33 cases, both abnormal group with 68 cases. The relationship among fetal heart rate, umbilical artery S/D value and fetal distress were observed.Results: The rate of little amniotic fluid(66.2%), umbilical cord around the neck(35.3%), amniotic contaminated 79.4%), Apgar score<7(50.0 %) and the probability of fetal distress(44.1%) in the fourth group were higher than the other three groups. The differences were statistically significant(x2=8.15,x2=13.54,x2=66.34,x2=11.90,x2=8.37;P<0.05).Conclusion: Fetal heart monitor combined with umbilical artery S/D monitoring and forecasting fetal distress has better efficiency, which can reduce maternal psychological and financial burden.

BACKGROUND:Studieshavesuggestedthat oncogene expression in liver cancer stem cels has a certain relationship withtheoccurrence and development of liver cancer, but there is stil a lack of research on bioinformatics and mechanisms.
OBJECTIVE:To identify differentialy expressed genes in liver cancer stem cels and to analyze these genes by bioinformatics.
METHODS:The human hepatoma cel line HepG2 was the cel tool of liver cancer stem cels to prepare total RNA, andfluorescent labelingexperiment was conducted.Usinggene chipshybridization, mRNA expression profiles were obtained and were screened, and then differentialy expressed mRNAs were obtained,GO and Pathway annotationswere analyzedusing bioinformatics.
RESULTS AND CONCLUSION:The detection rate was 73.21% for hybridization experiment, indicating the hybridization experiment is successful. In this study, a total of 38342 mRNA werefound, and after further analysis, 1236 differentialy expressed genes werescreened (P< 0.05, fold change≥2), including599up-regulated and637down-regulated genes, respectively (P< 0.05). Biological functions of differentialy expressed geneswere mainly involved inthe histone H4 acetylation, cel mitosis and proliferation, synthesis and decomposition of cel-associated proteins, chromosome segregation, cel differentiation and apoptosis, signaltransduction, as wel as nutrienttransportation and transcription. Pathway annotationsweremainly related to cytokine-mediated inflammatory signaling pathway, Wnt signaling pathway, Hedgehog and Notch signaling pathways, TGF-Beta, Jak-STAT and so on. These results demonstrate that differentialy expressed genes in liver cancer stem celsarerelatedto the occurrence of liver cancer, and may be involved in the regulation of signaling pathways, which provides a new target for the treatment of liver cancer.

Objective To evaluate the clinical value of laparoscopic and open radical gastrectomy for gastric cancer in advanced stage(D2).Methods A retrospective analysis was conducted in 100 patients with advanced gastric cancer who underwent surgical treatment.The patients were randomly divided into laparotomy group (n=44) and laparoscopic group (n=56).The laparotomy group was treated with D2 radical operation for advanced gastric cancer by the conventional laparotomy, while the laparoscopic group underwent laparoscopic radical resection of advanced gastric cancer with D2.The surgery related indicators, as well as intraoperative and postoperative complications etc.were compared between the two groups.All patients were followed up for 24 months.The recurrence, metastasis and mortality of the patients in the two groups were compared.Results The operation time and the amount of bleeding of the laparoscopic group were less than those of the laparotomy group (P=0.020, 0.001).The postoperative intestinal function recovery and hospitalization time of the laparoscopic group were shorter than those of the laparotomy group (P=0.020,0.001).There was no significant difference between the two groups in the number of lymph node dissection (P=0.650).Various complications occurred in the two groups, such as bleeding, spleen injury, vascular injury of colon injury and pancreatic injury, but the difference between the two groups was not statistically significant (P=1.000,0.570,1.000,1.000).There was no significant differences between the two groups in pancreatic fistula, anastomotic leakage, remnant stomach weakness and anastomotic bleeding (P=0.020,0.005,1.000,1.000,0.570).After 24 months of follow-up, there was no significant difference in recurrence, metastasis and mortality between the two groups (P=0.450,0.290,0.530).Conclusion Endoscopic surgery for D2 resection in the treatment of advanced gastric cancer has advantages, such as less trauma, rapid recovery and so on, can reduce the occurrence of postoperative complications.