1.Preparation and Quality Control of Fumeisong Cream
China Pharmacy 2001;0(07):-
OBJECTIVE: To prepare fumeisong cream and establish its quality control method. METHODS: Ingredients including carbamide, triamcinolone acetonide acetate, camphor, and laurocapram were mixed in an oil-in-water matrix for preparation of fumeisong cream. HPLC was adopted to determine the content of triamcinolone acetonide in the cream. RESULTS: The prepared cream was white in color, with test items all in line with specifications stipulated in 2005 version of China Pharmacopoeia. The linearity concentration range of triamcinolone acetonide was 2.06~20.6 ?g?mL-1(r=0.999 6) and the average recovery rate was 99.6% (RSD=1.0%,n=9). CONCLUSION: The cream is simple and feasible in preparation techniques, and its quality is stable and controllable.
2.The present situation of choice for supporting and bone grafting material for anterior reconstruction after debridement of spinal tuberculosis
International Journal of Surgery 2011;38(1):50-53
Tuberculosis of bone and joint most commonly occurs in spine, and the main treatment method is anterior debridement, bone grafting and internal fixation. Autologous bone is still considered the "gold standard" when the anterior reconstruction of spine after debridement is needed. Allogeneic bone, artificial bone and artificial intervertebral support bodies such as titanium mesh and some biological materials also have a broad clinical application, but still can not completely replace the autologous bone because of their defects. In the aspect of internal fixation, anterior fixation has become a conventional method for the patients who suffer from active spinal tuberculosis and need anterior debridement of the focus, because this method can provide good support. This review summarizes the present situation of choice for supporting and bone grafting material for anterior reconstruction after debridement of spinal tuberculosis.
3.Investigation on spondylolysis of lumbar vertebral arch in 100 recruits before and after reinforced training
Chinese Journal of Tissue Engineering Research 2006;10(4):164-165
BACKGROUND: The incidence rate of spondylolysis of lumbar vertebral arch in recruits is higher during the training, and it affects the normal training. OBJECTIVE: To analyze the correlation of the incidence rate of spondy lolysis of lumbar vertebral arch with training and the original lesions at waist in recruits. DESIGN: A randomized sampling survey. SETTING: Department of Orthopaedics, the 97 Hospital of Chinese PLA. PARTICIPANTS: Totally 100 male recruits aged 18.7 years averagely en rolled in 2003 were involved in the survey. METHODS: The 100 recruits were followed up for the whole course, the X-ray examination at lumbar vertebrae of right, lateral and two-slope positions were observed before training and after 100-day reinforced training. MAIN OUTCOME MEASURES: The incidence rates of spondylolysis of vertebral arch, and whether there was slippage and other aggravations in those with spondylolysis before were mainly observed. RESULTS: All the 100 recruits entered the analysis of results. ① The in cidence rate of spondylolysis of vertebral arch before and after training: Be fore training, 5 cases had spondylolysis of L5 vertebral arch, and the incidence rate was 5%. At the end of the 100-day training, 8 cases had spondylolysis of lumbar vertebral arch, and the incidence rate increased to 8%. ② The results of X-ray examination before and after training: The Xray examination showed that isthmus narrowing of left and L5 vertebral arch occurred in 2 cases and 1 case respect ively, and spondylolysis of bilateral L5 vertebral arches occurred in 5 cases, including 1 case of degree I slip page before training. At the end of the 100-day training, the degree I slip page and below occurred in 3 of the 5 cases with spondylolysis of bilateral L5 vertebral arches before, another 3 cases with original narrowing of lumbar vertebral arch all had breakage. CONCLUSION: The incidence rate of spondylolysis of vertebral arch is associated with the training intensity. It suggestes that the examination of spinal cord should be reinforced in enrolled recruits, and the items of Xray examination at lumbar vertebrae of right, lateral and two-slope positions should be added.
4.Effects of driving fatigue on working memory
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(12):1108-1109
Objective To investigate effects of driving fatigue on working memory. Methods The control group included 12 taxi drivers after adequate rest while the fatigue group included 27 taxi drivers who had been driving for 10h. Digit memory span, words span, Digit Subtraction Test, Random Number Generation test were used. Results Compared with the control(6.60 ±0.40,90.67 ±6.65,158.27 ±29.12,0.30 ±0.06,24.29 ±10.59,35.90 ± 10.64 ), driving fatigue group were significantly( P < 0.05 )different in the number of backward number memory span( 5.37 ± 0.72 ), percentage of number of right reaction of the number of total reaction of Digit Subtraction Test(79.95 ± 8.04), total number of RNG( 88.33 ± 19.48 ), RNG(0.40 ± 0.05 ), Coupon( 12.35 ±12.88), NSQ(49.72 ± 8.06). Conclusion Driving fatigue can decline the working memory.
5.Correlation between parameters of ambulatory blood pressure monitoring and prostatic volume in elderly men with essential hypertension
Chinese Journal of Geriatrics 2010;29(11):891-893
Objective To explore the correlation between the parameters of ambulatory blood pressure monitoring (ABPM) and prostatic volume in elderly patients with essential hypertension.Methods The 131 elderly patients with essential hypertension from March 2007 to December 2009 were enrolled in this study, including 102 benign prostatic hyperplasia (BPH) patients and 29 nonBPH (NBPH) patients. All patients underwent ABPM and ultrasound examination of prostate.Prostatic volumes (PV) were calculated and were compared between BPH group and NBPH group.Correlation between parameters of ABPM and PV was analyzed. Results (1)The maximal mean artery pressure (MAPmax) at night was higher in BPH group than in NBPH group [( 104.7 ± 12. 0)mm Hg vs. (99.6± 10. 1) mm Hg, P= 0.039]. (2)There were correlations between PV and MAPmax in all-day (r=0. 184, P=0. 035), MAPmax at daytime (r=0. 183, P=0. 037), MAPmax at night (r=0. 181, P=0. 040), respectively. Conclusions MAPmax of ABPM may be associated with PV in elderly patients with essential hypertension.
6.Analyses on the self-rated health status of college students majoring in physical education
Chinese Journal of Health Management 2008;2(2):83-85
Objective Find out the self-rated health of college students majoring in physical education and the influential factors, so as to offering some evidences which can help adopting adopt some measures to improve health condition. Methods Adopt method of random sampling to investigate the application of
7.Design and clinical application of anatomical steel plate for internal fixation of scapular neck fracture
Orthopedic Journal of China 2006;0(06):-
[Objective] To design anatomical steel plate for internal fixation of scapular neck fracmre.[Method]By observing the scapular structure and scapular fracture type,imaging a form of anatomical steel plate for internal fixation of scapular neck fracture,the needed relative measurement datum of scapula were obtained.Forty pairs of scapular spechnens of men and women were measured,relative datum were obtained.Based on the measurement,scapular neck fracture plate was designed.The steel plates were applied in patients with scapular neck fracture or scapular body fracture,patients were followed up after operations,the results were observed.[Result]Seven patients with scapular neck fracture or scapular body fracture were operated with the anatomical steel plates,the steel plates were obedient to the scapulas greatly,the fixations were strong,the operations were easy,the time of operations were short,seven patients were followed up for 12-18 months showing satisfactory results.[Conclusion]The design of anatomical scapular neck fracture steel plates is satisfactory,when using tile plate to fix scapular neck fracture.The fixation is strong,using the steel plate can be benificial to patient's early exercise.It has advantages of preventing complications,promoting fracture to heal,making the scapular operation easy,shortening the time of operation,lessening the blood in operation.This type of anatomical steel plate has the value to be popularized.
8.Effect of calcium channel blocker on the contractility and autorhythmicity of isolated instable detrusor strip in rats
Journal of Third Military Medical University 2003;0(21):-
Objective To investigate the effect of L-type and T-type calcium channel blocker on detrusor autorhythmicity, contractility in order to elucidate the pathogenesis of detrusor instability (DI). Methods Animal models of bladder outlet obstruction (BOO) were established in 33 female SD rats and another 10 served as normal control. Six weeks later, the changes of detrusor autorhythmicity and contractility were examined by means of cystometry and the in vitro detrusor strip study. Results The incidence rate of DI was 75.9%. The detrusor autorhythmicity and contractility increased evidently after BOO (P
9.Effect and significance of TNF-? to cardiomyocyte apoptosis in VMC
Chinese Journal of Immunology 1985;0(02):-
Objective:To study cardiomyocyte apoptosis of viral myocarditis (VMC) mice,study the effect and significance of Tumor Necrosis Factor-? (TNF-?) to cardiomyocyte apoptosis in VMC.Methods:Our experiments studied cardiomyocyte apoptosis at 3、5、7、9、15、35 days after virus inoculation in VMC mice by ways of TUNEL and electron microscope.We studied the effect of TNF-? to cardiomyocyte apoptosis in VMC by the way of intervention with TNF-? and TNF-? mAb.Results:Apoptotic cardiomyocyte of VMC mice increased appaently compared with control mice.Cardiomyocyte apoptosis increased after TNF-? intervention,cardiomyocyte apoptosis reduced after TNF-? mAb intervention.Conclusion:Abnormal cardiomyocyte apoptosis was observed in VMC,cardiomyocyte apoptosis may has relation with the Pathogenesis of VMC.TNF-? can induce cardiomyocyte apoptosis in VMC.TNF-? induces cardiomyocyte apoptosis may has relation with its role in VMC.
10.Development of hepatocyte transplantation
International Journal of Biomedical Engineering 2006;0(06):-
As a safe and effective treatment method of fulminic hepatic failure and end stage liver disease, hepatocyte transplantation has been widely verified in many animal experiment and clinical research. It has many advantages. For instances, It is safe and easy to perform. It causes little trauma and is convenient for retransplantation. The hepatocytes are less immunogenetic and the cells from one donor liver can be used for several patients, and so on. The cell source, route of transplantation, theoretical basis and clinical application of the method are reviewed in this paper.