1.Diagnosis and surgical treatment of relapsed gastric cancer.
Journal of Practical Medicine 2002;435(11):8-10
A study on 24 patients with the relapsed gastric cancer /764 patients with gastric cancer operated in ViÖt §øc Hospital during 1993-1997 has shown that the number of the relapsed gastric cancer account for 3,1% total number of operation for gastric cancer. 38,3% patients received the second operation within the first 6 - 24 month of the first operation. 70,8% patients found the invasive tumor vegetation in connective edge. Only 16,7% patients found non- invasive relapsed cancer in connective edge., short cut (20,8%); biopsy testing operation and jejunum-open for eating (12,5%); biopsy testing operation (37,5%).The post operative mortality rate(12,5%).
Stomach Neoplasms
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Diagnosis
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therapeutics
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surgery
2.Knowledge, attitude and behavior of risk factor HIV/AIDS in the teenage from 15 to 24 years in the key area of Ha Tinh province
Journal of Practical Medicine 2005;505(3):90-92
A cross-desribtive study consisted 480 children from 15 to 24 on KAP on HIV/AIDS on the villages, communes of Hatinh province. The result showed that: Right knowldege on the prevention of HIV/AIDS of the teenage who unmarried 67.3%, they still have wrong knowledge on the way to transmission and the prevention such as mosquito bite, share bowl, chopstick, no contact with IHV transmission. The HIV transmission. The propotion of HIV in male is low. The propotion of use drug addiction in the teenage whom unmarried is low (0.6%). These teenage who have sexual intercourse is 12.5%, low in use condom, include have sexual intercourse with prostitute. These are risk factors cuase HIV/AIDS in the teenage of Ha Tinh province.
HIV
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Acquired Immunodeficiency Syndrome
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Risk Factors
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Adolescent
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Knowledge
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Attitude
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Behavior
3.rpoB Gene Mutations in Rifampicin - Resistant Mycobacterium Tuberculosis Strains in Vietnam
Son Thai Nguyen ; Hong Thu Le ; Thuong Cong Phung
Journal of Medical Research 2008;0(1):44-51
Introduction: Mycobacterium tuberculosis resists rifampicin (RIF) because of mutations in the rpoB (the p subunit of RNA polymerase) gene, mostly in the 81 bp region. \r\n', u'Objectives: Identify the frequency and characteristics relative to drug - resistant rpoB gene mutation in RIF - resistant M. tuberculosis strains. \r\n', u'Subjects and method: 40 M. tuberculosis strains including 11 RIF - sensitive strains and 29 RIF - resistant strains. Some bio molecular techniques were used such as extracting mycobacterial DNA, PCR, cloning, sequencing and analyzing mutation related RIF - resistance on rpoB gene. \r\n', u'Results: No mutation was found on the 81 bp region of rpoB gene of the RIF - sensitive M. tuberculosis strains. The rate of mutation on rpoB gene of 29 RIF - resistant M. tuberculosis strains is 96.6%. We found 12 mutation codon positions on the 81 bp region of the rpoB gene, and the mutation codon positions with high frequency were 531 (51.7%) and 526 (31%). The mutation position found in only one strain is codon 519 (3.4%) but not found in other reports. There are 15 types of drug resistant mutations in which TCG531 TCG is the most common with 50%. Multi - drug resistance was seen in mutable and none mutable cases, with all codon positions and mutable forms. \r\n', u'Conclusion: No mutation was found on the 81 bp region of the rpoB gene of RtF - sensitive M. tuberculosis strains. The rate of mutation on the rpoB gene of RIF - resistant M. tuberculosis strains is 96.6%. The new mutation position found is codon 519. The mutation on the rpoB gene does not determine the multi - drug resistance of M. tuberculosis. \r\n', u'
Mutation
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rpoB gene
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Rifampicin - resistant M. tuberculosis
4.Primary result of building a street food safety and hygiene model in Hue city
Hong Xuan Duong ; Son Dinh Nguyen ; Hoa Thai Nguyen ; Dam -- Tran ; Nam Huu Hoang ; Oanh Dinh Tran ; Linh Van Bach
Journal of Preventive Medicine 2007;17(4):27-32
Background: Hue city is a cultural and tourism center of The middle and the whole country. Beside developing tourism services, food processing establishments, traditional specialities, eating and drinking services especially street food services more and more develop plentifully and multiform, satisfy daily demand of consumers. Objectives: Assessment on improvement level on some targets of street food safety and hygiene after 2 years intervention. Subjects and method: All street food processing establishments in 3 wards: V\u0129nh Ninh, Ph\xfa H\u1ed9i, V\ufffd?D\ufffd?of Hue city. Method: Cross-sectional study with comparison before and after intervention. Results: Kitchen utensils samples have met hygiene requirements and the proportion of food samples without borax both increase. The infection rate of bacteria in cook\ufffd?hands, kitchen utensils, cooked food were improved after 2 years carried out targeted model. Clean water for processing street food have not enough although 100% households use running water. The proportion of people were trained about food safety and hygiene knowledges and health examination increase. The situation of using food colourings and poisonous additives decrease remarkably. Salesclerks have more consciousness of preserving and covering food. 86,4% of food processing establishments have recycle bins obtain requirement to reduce polluted food. Conclusion: Street food is an important stage of food supplying network in 3 wards above. Somewhere having interest of Government and local authorities, Steering committee have efficient activities street food model develop conveniently.
Food Safety/ methods
5.Remarks on food safety and hygiene at Thua Thien Hue province (1992 - 2006)
Hoa Thai Nguyen ; Son Dinh Nguyen ; Dam Tran ; Hong Xuan Duong ; Hao Van Huynh ; Loc Danh Tran
Journal of Preventive Medicine 2007;17(4):22-26
Background: At present, management and supervision on food safety and hygiene quality have many difficulties because supervisory system from province to district, commune is still insufficient. Objectives: Assessment on food safety and hygiene situation at Thua Thien Hue province, propose solutions to intensify State management on food safety and hygiene quality and step by step enhance efficiency of food safety and hygiene activities in the next years. Subjects and method: Food processing establishments at Thua Thien Hue province. Method: Inspection in Action months for food safety and hygiene, supervision usually on food processing establishments were chosen accidentally in area. Food samples were inspected indexes of microorganisms, physicochemical have met the criteria of Ministry of Health. Results: The proportion of food processing establishments and cafeterias which have not met the regulations on food safety and hygiene was decreasing from 40,93% to 27,45%. Also in 2002-2006, 36,71% of kitchen utensils and the cooks\ufffd?hands failed to meet the regulations. Regarding to microorganisms, the indices of ice-cream, bean sweet porridge and soft drinks had improved remarkably. The index of ice had been decreased from 33,02% to 22,56%. 45,25% of bowls and plates didn\u2019t meet chemical and physical criteria. 68,4% of food colourings didn\u2019t meet criteria because inorganic and industrial colourings were used. Traditional foods still contain borax although the prevalence is decreasing from 65% to 35%. Ice cream and bean sweet porridge cooked with saccharine were 37,34%. Conclusion: Understanding of producers and consumers about food have still many limitations.
Food Safety/ methods
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6.The situation of child injury by injury supervision at Viet Duc hospital in 2006
Chinh Duc Nguyen ; Lap Doc Cao ; Huy Danh Luu ; Nhung Kim Nguyen ; Bich Van Nguyen ; Son Hong Trinh ; Quyet Tien Nguyen ; Tu Thi Hong Nguyen ; Lan Thi Ngoc Tran ; Trang Thi Quynh Khieu ; Anh Mai Luong
Journal of Surgery 2007;57(2):18-27
Background: According to WHO, there are 5 million deaths from kinds of injury a year in the world, of which 875000 deaths occur in children under 18 years old. Injury leads to 40000 deaths which account for 10.7% deaths due to all other causes a year in VietNam. Objective: To show conclusions of the situation of child injury, recommendations for prevention of child injury and methods in order to enhance emergency activity in Vietnam. Subjects and method: The authors collected information about all patients who had emergencies due to injury at Viet Duc hospital, from March 26th 2006 to Octorber 26th 2006. However, supervised cases were the patients under 18 years old who were examined and treated at the Department of Emergency. Results: During the period of study, 2536 patients under 18 years old were examined for injury, of which death and coming back home for death were 83 cases (3.27%). 974 children had emergency resulted from injury: male was more than female: 697 verus 227. The leading causes of child injury were fall and traffic accident, respetively 34% and 60%. The most common traumas were traumatic brain injury (45%), limbs injury (41%). Although most of cases had first aid at the hospitals in district or province level, the rate of non-first aid cases was high (34%). Conclusion: Child injury is a leading cause of child death in hospitals. Methods for prevention of child injury should focus on educating and propagandizing to minimize injuries caused by traffic accident and fall.
Wounds and Injuries
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Child
7.Identification of Enterovirus C105 for the first time in New Zealand
Cong Thanh Duong ; Tran Hien Nguyen ; Anh Tuan Nguyen ; Thi Thanh Ha Hoang ; Hong Thang Pham ; Thi THanh Ha Nguyen ; Anh Tuan Le ; Dai Quang Tran ; Hong Tram Tran ; Le Hai Nguyen ; Thi Thu Huong Phan ; Hai Son Vo ; Hoang Duc Bui ; Thien Nga Nguyen ; David Jacka ; Keith Sabin
Western Pacific Surveillance and Response 2015;6(1):52-54
In this report we describe a new approach in HIV sentinel surveillance that was piloted in Viet Nam in 2009 and is currently being rolled out in all provinces. It comprises a brief behavioural questionnaire added to the HIV sentinel surveillance surveys conducted routinely among people who inject drugs, female sex workers and men who have sex with men. Timely reporting of data from this system has resulted in improvements to HIV prevention efforts for most at-risk populations.
8.The role of rapid tissue expansion in separating xipho-omphalopagus conjoined twins in Vietnam
Tran Thiet SON ; Pham Thi Viet DUNG ; Ta Thi Hong THUY ; Vu Duy KIEN ; Nguyen Thanh LIEM
Archives of Plastic Surgery 2021;48(4):378-383
Conjoined twins are rare, and each set of conjoined twins has a unique conjoined anatomy. It is necessary to perform separation to increase the chance of patient survival. Tissue expansion is an advanced technique for providing sufficient soft tissue and skin for wound closure. We report the successful application of rapid tissue expansion in 10-month-old xipho-omphalopagus conjoined twins in Vietnam. A tissue expander was placed on the anterior body between the sternum and umbilicus with a baseline of 70 mL sterile saline (0.9% NaCl). The first injection into the tissue expander began on the 6th day after expander insertion, and injections continued every 2 days with approximately 30–70 mL per injection according to the expansion of the skin. The expander reached 335 mL after six injections and within 10 days. In order to prepare for surgical separation, expansion was completed on the 15th day after insertion. The expanded skin area was estimated to be 180 cm2, which was sufficient to cover both patients’ skin deficiencies. The twins presented for surgical separation 6 days following the completion of tissue expansion. Both babies were discharged in good health 1 month after separation.
9.The role of rapid tissue expansion in separating xipho-omphalopagus conjoined twins in Vietnam
Tran Thiet SON ; Pham Thi Viet DUNG ; Ta Thi Hong THUY ; Vu Duy KIEN ; Nguyen Thanh LIEM
Archives of Plastic Surgery 2021;48(4):378-383
Conjoined twins are rare, and each set of conjoined twins has a unique conjoined anatomy. It is necessary to perform separation to increase the chance of patient survival. Tissue expansion is an advanced technique for providing sufficient soft tissue and skin for wound closure. We report the successful application of rapid tissue expansion in 10-month-old xipho-omphalopagus conjoined twins in Vietnam. A tissue expander was placed on the anterior body between the sternum and umbilicus with a baseline of 70 mL sterile saline (0.9% NaCl). The first injection into the tissue expander began on the 6th day after expander insertion, and injections continued every 2 days with approximately 30–70 mL per injection according to the expansion of the skin. The expander reached 335 mL after six injections and within 10 days. In order to prepare for surgical separation, expansion was completed on the 15th day after insertion. The expanded skin area was estimated to be 180 cm2, which was sufficient to cover both patients’ skin deficiencies. The twins presented for surgical separation 6 days following the completion of tissue expansion. Both babies were discharged in good health 1 month after separation.
10.NO Production Inhibition of Lignans from Vietnamese Schisandra sphenanthera Rehd. et Wils. Fruits
Hong Khuyen THI PHAM ; Phu Chi Hieu TRUONG ; Khanh Huyen THI PHAM ; Dao Cuong TO ; Manh Hung TRAN ; Tu Nguyen THI THANH
Natural Product Sciences 2023;29(4):312-322
In the present study, bioactivity-guided extraction and isolation of the n-hexane fraction of the fruits of Vietnamese Schisandra sphenanthera led to the isolation of five dibenzocyclooctadiene lignans as gomisin N (1), schisandrin C (2), gomisin H (3), gomisin D (4), and gomisin C (5). All the isolates were tested for their inhibition of NO production in LPS-induced RAW 264.7 cells. Among them, compounds 4 and 5 showed weak inhibition of NO production with IC 50 values of 25.0 ± 1.6 and 24.8 ± 2.0 µM, respectively. Compound 1 exhibited NO production inhibition with an IC 50 value of 15.8 ± 2.1 µM, meanwhile, schisandrin C (2) showed the most potent inhibition with an IC 50 value of 8.5 ± 0.5 µM. In addition, compound 2 had a concentrationdependent inhibitory effect on the protein expression of the inflammatory enzymes iNOS and COX-2. Their physicochemical properties and ADMET data were predicted by in silico, indicating favorable drug-like properties as well as low acute oral toxicity. The results suggest that the fruit of S. sphenanthera and its phytochemical constituents might be used as anti-inflammatory agents.