4.Virtual reality-assisted management of communicated solitary fibrous tumor in skull base: a case report.
Wang Hu ZHENG ; Chao LI ; Yu Qiu ZHOU ; Yong Cong CAI ; Teng LI ; Jian JIANG ; Rong Hao SUN ; Chun Yan SHUI ; Xu WANG ; Tian Qi HE ; Yu Dong NING ; Gang QIN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2022;57(1):65-68
5.A Rare Solitary Fibrous Tumor of the Pleura with Extensive Cystic Change.
Chang Woo CHOI ; Keun HER ; Yong Soon WON
Soonchunhyang Medical Science 2013;19(2):108-109
A right pleural mass was detected incidentally in a 52-year-old woman and chest computed tomography showed lobulated pleural mass. Thoracoscopic excision was performed. Histology showed solitary fibrous tumor with extensive cystic change. Solitary fibrous tumor with extensive cystic change is very rare and we treated this tumor successfully with video-assisted thoracic surgery.
Female
;
Humans
;
Middle Aged
;
Pleural Neoplasms
;
Pneumothorax
;
Solitary Fibrous Tumor, Pleural*
;
Solitary Fibrous Tumors*
;
Thoracic Surgery, Video-Assisted
;
Thorax
6.A Case of Intracranial Solitary Fibrous Tumor.
Ying-Qian CHEN ; Jun-Ji WEI ; Ren-Zhi WANG ; Yun-Xiao MENG ; Wen-Bin MA ; Xin-Jie BAO ; Ke-Yin CHEN ; Yu WANG ; Yong-Ning LI
Chinese Medical Journal 2016;129(22):2767-2768
7.Clinicopathological features of spinal solitary fibrous tumor.
Hai Jing GE ; Jing Jing YAO ; Li LI ; Bo Wen LI ; Cui GE ; Hao LIU ; Yong LI ; Hong Fang YIN
Chinese Journal of Pathology 2022;51(9):875-880
Objective: To investigate the clinicopathological, molecular genetic, immunohistochemical and prognostic features of spinal solitary fibrous tumor (SFT). Methods: The clinical data of 12 cases of spinal SFT in Beijing Tsinghua Changgung Hospital, Affiliated to Tsinghua University, diagnosed from January 2015 to December 2021 were collected and reclassified. The clinical data, histopathology, immunohistochemistry and molecular genetics were analyzed. Follow-up and related literature reviews were conducted. Results: Among the 12 patients, there were 5 males and 7 females; the age ranged from 31 to 73 years, with a median age of 50.5 years. All 12 cases were primary tumors, including 4 cases diagnosed at the first time and 8 recurrent cases. Among the 12 cases, 8 were WHO grade 1, 3 were WHO grade 2, and 1 was WHO grade 3. Microscopically, the spinal SFT appeared as a spindle cell tumor, the stroma was rich in many thin-walled blood vessels with various histological features such as cell morphology and necrosis according to the different tumor grade. All (12/12) of the cases expressed vimentin and STAT6 (diffuse and strong nuclear stain), 11 cases (11/12) expressed both CD34 and bcl-2, and 7 cases (7/12) expressed CD99. Next-generation sequencing showed that 12 (12/12) of the patients had NAB2-STAT6 gene fusion. The 12 patients were followed up for 6 to 80 months. There were no recurrences or metastases in the 4 first cases after operation. Among the 8 recurrent cases, 2 of the patients relapsed and 2 died. Conclusions: Spinal SFT is rare and has a high recurrence tendency. Many aspects need to be considered in the diagnosis process. STAT6 is a relatively specific marker for the diagnosis of this tumor. Complete surgical resection is the preferred treatment while postoperative radiotherapy is recommended to reduce tumor recurrence.
Adult
;
Aged
;
Female
;
Humans
;
Immunohistochemistry
;
Male
;
Middle Aged
;
Prognosis
;
Solitary Fibrous Tumors/surgery*
Result Analysis
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