Necrotizing fasciitis is a rapidly progressive invasive soft tissue infection that is rarely seen in craniocervical area. In the majority of cases described in the medical literature, there has been an identifiable initiating event such as instrumentation or other trauma to the skin. Because of the rapid progression of the infection, the key to a successful outcome is early recognition and rapid initiation of definitive surgical management. A case is presented in which necrotizing fasciitis was seen in a craniocervical area with instrumentation especially dental extraction.
Fasciitis, Necrotizing* ; Skin ; Soft Tissue Infections

No abstract available.
Immunocompromised Host* ; Mycoplasma hominis* ; Mycoplasma* ; Skin* ; Soft Tissue Infections*

Mycobacterium abscessus is a rapidly-growing bacterium which spreads everywhere in the natural world. Lung infection is the most common infection that it causes, but skin and soft tissue infections can occur after injections, operations, or other trauma. We report a case of subcutaneous infection caused by M. abscessus followed by an intramuscular injection.
Clarithromycin ; Injections, Intramuscular ; Lung ; Mycobacterium ; Skin ; Soft Tissue Infections

Mycobacterium massiliense (M. massiliense) was identified recently as a species that separated from M. abscessus. Unlike M. abscessus, M. massiliense responds well to clarithromycin-based antibiotic treatment. Many cases of M. massiliense infections related to iatrogenic procedures have been reported. We report a case of skin and soft tissue infection by M. massiliense, which was not caused by medical appliances, that was treated successfully using clarithromycin monotherapy for -6 months after initial treatment with empirical antibiotics for 4 weeks.
Anti-Bacterial Agents ; Clarithromycin ; Mycobacterium Infections ; Mycobacterium* ; Nontuberculous Mycobacteria ; Skin* ; Soft Tissue Infections*

Non-tubecrulosis mycobacterium infections were increasingly reported either pulmonary or extrapulmonary in the past decades. In Taiwan, we noticed several reports about the soft tissue infections caused by rapid growing mycobacterium such as Mycobacterium abscessus, Mycobacterium chelonae, on newspaper, magazines, or the multimedia. Most of them occurred after a plastic surgery, and medical or non-medical procedures. Here, we reported two cases of these infections following medical procedures. We also discussed common features and the clinical course of the disease, the characteristics of the infected site, and the treatment strategy. The literatures were also reviewed, and the necessity of the treatment guidelines was discussed.
Multimedia ; Mycobacterium chelonae ; Mycobacterium Infections ; Mycobacterium* ; Periodicals ; Periodicals as Topic ; Soft Tissue Infections* ; Surgery, Plastic ; Taiwan

Cervical necrotizing fasciitis is a rare but life-threatening soft tissue infection primarily affecting the superficial and deep fascial planes. If proper treatment is delayed, the infection may cause extensive necrosis of overlying skin, destroying fascia, adipose tissue and muscle and producing severe systemic toxicity. So the key to the successful outcome is early recognition and rapid initiation of definitive radical debridement. The authors report, along with a literature review, one case of necrotizing fasciitis spreading into the anterior chest wall.
Adipose Tissue ; Debridement ; Fascia ; Fasciitis, Necrotizing ; Muscles ; Necrosis ; Skin ; Soft Tissue Infections ; Thoracic Wall ; Thorax

Tigecycline is a broad spectrum antibiotic which has been used for complicated intra-abdominal infection and complicated skin and soft tissue infection by multi-drug resistant bacteria. However recent meta-analysis studies have raised a concern for adverse events of tigecycline. We analyzed retrospectively adverse events, associated factors of adverse events in multi-drug resistant bacteria caused infections treated with tigecycline in Korean patients. One hundred-sixty patients treated with tigecycline from July 2009 to September 2013 were enrolled in this study. Their clinical and microbiologic data were reviewed. History of invasive procedure within 7 days and recent operation within 3 months were associated with adverse events. The most common adverse events were nausea and vomiting. Associated factors of nausea were soft tissue injury and recent operation within 3 months. In this study, nausea was the most common adverse event in patients who received tigecycline. Although it is not serious complication, monitoring of adverse events is required to increase compliance.
Bacteria ; Compliance ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Incidence* ; Intraabdominal Infections ; Nausea ; Retrospective Studies ; Skin ; Soft Tissue Infections ; Soft Tissue Injuries ; Vomiting

Stenotrophomonas maltophilia is a ubiquitous, Gram-negative organism. It is an emerging causative pathogen for severe hospital- acquired infections, particularly in debilitated or immunocompromised patients because of its resistance to various antibiotics. Soft tissue infection caused by S. maltophilia, however, is uncommon. A patient with leukemia was referred for the evaluation of subcutaneous nodules that developed after chemotherapy. With the pathological finding of neutrophilic panniculitis, S. maltophilia was confirmed in a bacteriological study of the biopsied tissue. The nodules regressed spontaneously with recovery from the neutropenia. We report a case of S. maltophilia infection that manifested as soft tissue nodules, which resolved spontaneously in a patient with leukemia.
Anti-Bacterial Agents ; Humans ; Immunocompromised Host ; Leukemia ; Neutropenia ; Neutrophils ; Panniculitis ; Soft Tissue Infections ; Stenotrophomonas ; Stenotrophomonas maltophilia

Antithyroid drugs (ATD) has been widely used to treat Graves' disease. However agranulocytosis, a serious fatal complication of ATD treatment, occurs in about 0.5 percent. The symptoms may mimic viral infections (fever, sore throat), and the potentially life-threatening pyogenic infections can go unrecognized initially. The median duration of drug exposure before the onset of acute agranulocytosis is within 30 days in most cases. We report a case of agranulocytosis with secondary soft tissue infection and abscess occuring after increasing the dose of methimazole in a woman who had taken methimazole for more than 10 years. We administered broad-spectrum antibiotics and aspirated the soft tissue abscess. A review of the medical literature regarding agranulocytosis in the setting of ATDs is presented.
Abscess ; Agranulocytosis ; Anti-Bacterial Agents ; Antithyroid Agents ; Female ; Graves Disease ; Humans ; Hydrazines ; Methimazole ; Soft Tissue Infections

A 20-year-old man developed necrotizing fasciitis of the left chest wall complicating acupuncture. Necrotizing fasciitis is a highly morbid soft tissue infection that rarely involves the upper torso. In the past, there has been few report on necrotizing fasciitis complicating acupunture in the English literature (based on a MEDLINE search covering 1966 to 2005). We present this extremely unusual case of a patient after taking acupuncture who survived severe necrotizing fasciitis of the chest wall following wide debridement of the necrotic tissue and broad-spectrum antibiotic therapy.
Acupuncture* ; Debridement ; Fasciitis, Necrotizing* ; Humans ; Soft Tissue Infections ; Thoracic Wall* ; Thorax* ; Torso ; Young Adult