To search for the more effective amblyopia treatment, we prospectively compared the results of initial group and alternative group with use of Min's glasses. Initial and alternative groups consisted of 18 and 64 patients. 15 patients (83.3%) of initial group were compliant with the treatment while 50 patients(78.1%) of alternative group were. No significant differences existed between them based on age, sex, causes of amblyopia and initial visual acuity (P>0.05). Average visual acuity improvements were 2.13 +/- 1.81 lines in initial group, compared to 2.51 +/- 1.50 lines in alternative group and no significant differences existed between them according to age, causes of amblyopia and initial visual acuity (P>0.05), However, in cases of female, there was significant visual acuity improvement in alternative group in comparision with initial group (P=0.034). In conclusion, Min's glasses were effective not only in initial treatment group but also in alternative treatment group, and in female patients who previously failed with conventional occlusion therapy the effect was more pronounced than male patients.
Amblyopia ; Child* ; Compliance ; Eyeglasses* ; Female ; Glass* ; Humans ; Male ; Prospective Studies ; Visual Acuity

Autoimmune hepatitis is an inflammatory liver disease characterized histologically by a dense mononuclaear cell infiltration of the portal tract, serologically by the presence of non-organ and liver specific autoantibodies and increased concentrations of IgG in the absence of a known etiology. Two types of autoimmune hepatitis are classified in the peripheral blood of antinuclear antibody and/or in antismooth muscle antibody (ANA/ASMA) or liver-kidney microsomal type 1 antibody (LKM-1). Type I (ANA/ASMA positive) and type II (LKM-1 positive) autoimmune hepatitis in children have clinical, biochemical, and histologic differences. We have experienced a case of type I autoimmune hepatitis in a 9-year-old girl. She had shown highly elevated IgG, high serum transaminase and marked hepatosplenomegaly. And so serologically ANA and ASMA were positive, histological findings of the liver biopsy were compatible with chronic active hepatitis. She was medicated with prednisone, but symptoms did not improved. Now she is receving conservative regimens.
Antibodies, Antinuclear ; Autoantibodies ; Biopsy ; Child* ; Female ; Hepatitis, Autoimmune* ; Hepatitis, Chronic ; Humans ; Immunoglobulin G ; Liver ; Liver Diseases ; Prednisone

Autoimmune hepatitis is an inflammatory liver disease characterized histologically by a dense mononuclaear cell infiltration of the portal tract, serologically by the presence of non-organ and liver specific autoantibodies and increased concentrations of IgG in the absence of a known etiology. Two types of autoimmune hepatitis are classified in the peripheral blood of antinuclear antibody and/or in antismooth muscle antibody (ANA/ASMA) or liver-kidney microsomal type 1 antibody (LKM-1). Type I (ANA/ASMA positive) and type II (LKM-1 positive) autoimmune hepatitis in children have clinical, biochemical, and histologic differences. We have experienced a case of type I autoimmune hepatitis in a 9-year-old girl. She had shown highly elevated IgG, high serum transaminase and marked hepatosplenomegaly. And so serologically ANA and ASMA were positive, histological findings of the liver biopsy were compatible with chronic active hepatitis. She was medicated with prednisone, but symptoms did not improved. Now she is receving conservative regimens.
Antibodies, Antinuclear ; Autoantibodies ; Biopsy ; Child* ; Female ; Hepatitis, Autoimmune* ; Hepatitis, Chronic ; Humans ; Immunoglobulin G ; Liver ; Liver Diseases ; Prednisone