Purpose: The purpose of this study was to identify the unmet needs experienced by patients discharged after cancer surgery in order to develop a systematic discharge plan. Methods: In-depth interviews were conducted on 20 patients within one year after major cancer surgery in Korea. Data were collected from August 19 to September 26, 2019, and the interview data were analyzed by Qualitative Content Analysis using the MAXQDA 2018 software to derive categories and subcategories of the study. Results: The needs for discharge planning for cancer patients consisted of four categories (physical needs, informational needs, mental health needs, social needs) and seven subcategories. Conclusion To meet the unmet needs of cancer patients for discharge planning, proper support and services at a hospital, and at a community and national level should be in place. The categories and subcategories formulated through this study can be used as basic data for the development of a standard evaluation form and interventions when planning cancer patient discharge.

Purpose: The purpose of this study was to identify the unmet needs experienced by patients discharged after cancer surgery in order to develop a systematic discharge plan. Methods: In-depth interviews were conducted on 20 patients within one year after major cancer surgery in Korea. Data were collected from August 19 to September 26, 2019, and the interview data were analyzed by Qualitative Content Analysis using the MAXQDA 2018 software to derive categories and subcategories of the study. Results: The needs for discharge planning for cancer patients consisted of four categories (physical needs, informational needs, mental health needs, social needs) and seven subcategories. Conclusion To meet the unmet needs of cancer patients for discharge planning, proper support and services at a hospital, and at a community and national level should be in place. The categories and subcategories formulated through this study can be used as basic data for the development of a standard evaluation form and interventions when planning cancer patient discharge.

We aimed to analyze the drug resistance patterns of multidrug-resistant and extensively drug-resistant tuberculosis (TB) and the difference of drug resistance among various settings for health care in Korea. The data of drug susceptibility testing in 2009 was analyzed in order to secure sufficient number of patients from various settings in Korea. Patients were categorized by types of institutions into four groups, which comprised new and previously treated patients from public health care centers (PHC), the private sector, and Double-barred Cross clinics (DBC). The resistance rates to first-line drugs were uniformly high in every group. While the resistance rates to second-line drugs were not as high as first-line drugs, there was a pattern that drug resistance rates were lowest for PHC and highest for DBC. The differences of the resistance rates were more prominent for oral second-line drugs. Our findings implied that drug resistance to oral second-line drugs was significantly amplified during multidrug-resistant-TB treatment in Korea. Therefore, an individualized approach is recommended for treating drug-resistant-TB based on susceptibility testing results to prevent acquisition or amplification of drug resistance.
Delivery of Health Care ; Drug Resistance* ; Extensively Drug-Resistant Tuberculosis* ; Humans ; Korea* ; Private Sector ; Public Health ; Tuberculosis, Multidrug-Resistant

This preliminary study was intended to clarify the effect of intraoperative fluid therapy on Acid-Base balance of the use of Hartmann's solution and 5% Dextrose solution. The arterial carbon dioxide partial pressure and oxygen partial pressure and pH are basic indices of the adequacy of ventilation in anesthetized patients, respiratory care and intensive care. In order to achieve this goal, the data collections were done at the Department of Anesthesia in Hanil Hospital from Mar., 1980 to Aug., 1980. The samplings, 20 cases, were included A.S.A. class I and II. We used 1,500 to 1,800cc/2hrs. of Hartmann's solution and 1,000cc/2hrs, of 5% Dextrose solution each 10 patients through the operative period. Observations were made for the followings; pH, PaCO2HCO-3. From the results of this study, there were no significant relationship between the use of 5% Dextrose solution and Hartmann's solution on Acid-Base balance during the intraoperative period.
Acid-Base Equilibrium* ; Anesthesia ; Carbon Dioxide ; Critical Care ; Fluid Therapy* ; Glucose* ; Humans ; Hydrogen-Ion Concentration ; Intraoperative Period ; Oxygen ; Partial Pressure ; Ventilation

Injury to the limbic system can result in amnesia, language difficulties, behavioral abnormalities, and psychological disorders. We present a patient who suffered psychosis related to disconnection of the limbic system after intraventricular and orbitofrontal hemorrhages following removal of a sellar meningioma. Diffusion tensor tractography was valuable for evaluating the structural integrity of the injured limbic tracts and determining the regeneration of tracts corresponding to neuropsychiatric recovery after cognitive rehabilitation.

Injury to the limbic system can result in amnesia, language difficulties, behavioral abnormalities, and psychological disorders. We present a patient who suffered psychosis related to disconnection of the limbic system after intraventricular and orbitofrontal hemorrhages following removal of a sellar meningioma. Diffusion tensor tractography was valuable for evaluating the structural integrity of the injured limbic tracts and determining the regeneration of tracts corresponding to neuropsychiatric recovery after cognitive rehabilitation.

No abstract available.
Mediastinum*

Infants, born with a birth weight above 4.0 kg, are categorized as high birth weight infant (HBWI). The term HBWI is often used in similar context with macrosomia. Macrosomia is associated with many complications, and is considered to be a high risk group that requires an intensive care in most cases. This report is presenting an extreme macrosomia born at a gestational age of 38+5 weeks, with a body weight of 6.14 kg. The infant was born by a cesarean section from a mother with diabetes, and was admitted into an intensive care unit with tachypnea, which had occurred soon after birth. There were other complications, such as hypoglycemia, hypocalcemia, secondary atrial septal defect, patent ductus arteriosus, pulmonary hypertestion, and etc. With conservative management, the symptoms improved over a 10 day course and the patient was discharged from the hospital. To this day, the child has not presented with further health problems during the 6 months of follow up period. We reviewed the frequency and trend of the births of HBWI, through the raw data from the Statistics Korea on births between 2000 and 2010. With additional analysis of the cases of macrosomia, through the years of 1964 to 2011, we were able to find 7 reports, including this current case of infants born with a body weight above 6.0 kg. This case was the fifth heaviest infant among these 7 cases. We are reporting this case with the hope that it may contribute to the future care of high risk infants in a neonatal intensive care unit.
Benzeneacetamides ; Birth Weight ; Body Weight ; Cesarean Section ; Child ; Ductus Arteriosus, Patent ; Female ; Follow-Up Studies ; Gestational Age ; Heart Septal Defects, Atrial ; Humans ; Hypocalcemia ; Hypoglycemia ; Infant ; Infant, Newborn ; Critical Care ; Intensive Care Units ; Intensive Care, Neonatal ; Korea ; Mothers ; Parturition ; Piperidones ; Pregnancy ; Tachypnea

PURPOSE: To investigate the prevalence of amblyogenic risk factors in the primary family members (parents, siblings) of patients with exotropia. METHODS: The authors of the present study examined primary family members including parents and siblings of 58 exotropia patients in our clinic. Best corrected visual acuity, refractive error, and cover-uncover test were performed. A total of 49 normal children's family members (control group) were examined in a similar manner. The prevalence of significant ocular findings were determined and compared to the control group. RESULTS: In 58 eligible families (153 subjects except proband), 65.4% had significant ocular findings: In parents, anisometopia, astigmatism, hyperopia, and strabismus were found at a rate of 18.1%, 31.1%, 2.5%, and 11.2%, respectively. In siblings, anisometropia, astigmatism, hyperopia, and strabismus were found at a rate of 24.3%, 24.3%, 5.4%, and 18.9%, respectively. Compared to the control group, in parents of exotropia patients, anisometropia, astigmastim, and strabismus were observed at a higher rate. In siblings, anisometropia, and strabismus were observed at a higher rate. CONCLUSIONS: Primary family members of exotropia patients have a high prevalence of amblyogenic risk factors. The present study offers rationale for providing comprehensive eye exams for parents and children with a family history of exotropia.
Anisometropia ; Astigmatism ; Child ; Exotropia ; Eye ; Humans ; Hyperopia ; Parents ; Prevalence ; Refractive Errors ; Risk Factors ; Siblings ; Strabismus ; Visual Acuity

BACKGROUND: Fentanyl, which is a potent synthetic micron-opioid receptor agonist, is one of the most widely used opioids in anesthesia and pain control. However, the pharmacodynamics of fentanyl show wide inter-individual variability. Therefore, this study was conducted to evaluate the influence of the blood-brain barrier transporter protein, p-glycoprotein, and micron-opioid receptor genetic polymorphism on fentanyl pharmacodynamics. METHODS: Seventy-nine patients who underwent posterior lumbar interbody fusion (PLIF) were included in this study. Postoperatively, the patients received fentanyl via an intravenous patient controlled analgesia device. The cumulative fentanyl doses and other pharmacodynamic data were then recorded at 2 h, 6 h, 12 h, 24 h and 48 h after the operation. In addition, genomic DNA was isolated from the patient's peripheral leukocytes and then evaluated for the presence of OPRM1 A118G and ABCB1 C3435T genetic polymorphism using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). RESULTS: The results of this study indicated that ABCB1 C3435T genetic polymorphism may be related to the cumulative fentanyl requirement for postoperative pain control. However, these findings were not statistically significant (P = 0.09). In addition, no relationship was observed between OPRM1 A118G and the cumulative postoperative fentanyl requirement. However, the cumulative postoperative fentanyl requirement was lower in the TTAA group (ABCB1 3435 TT, OPRM1 118 AA) than in the CCGG group (ABCB13435 CC, OPRM1 118 GG). CONCLUSIONS: The ABCB1 C3435T polymorphism may affect fentanyl pharmacodynamics. However, further studies are required to confirm the relationship between p-glycoprotein and fentanyl.
Analgesia, Patient-Controlled ; Analgesics, Opioid ; Anesthesia ; Blood-Brain Barrier ; DNA ; Fentanyl ; Humans ; Leukocytes ; P-Glycoprotein ; Pain, Postoperative ; Pharmacogenetics ; Polymorphism, Genetic