1.Mucous Gland Adenoma of the Bronchus: A case report.
Korean Journal of Pathology 1985;19(3):368-373
Mucous gland adenoma, one type of bronchial adenoma, is first introduced by Rosenblum and Klein2) in 1935 and very rare. Only twenty-one cases had been reported in english literature. This tumor must be differentiated from other types of bronchial adenoma because of completely benign clinical course. A case of mucous gland adenoma is presented which showed marked secondary calcification.
Adenoma
2.Immunohistochemical Characterization of the Salivary Gland Tumors.
Jung Hoon YOON ; So Young JIN ; Chan Il PARK
Korean Journal of Pathology 1987;21(3):144-152
It has been clarified that myoepithelial cells contain S-100 protein which is known to be a marker protein of neural tissue. To evaluate the participation of myoepithelial cells in the histogenesis of the salivary gland tumors, normal salivary glands and various salivary gland tumors were stained by immuno-peroxidase method. PAP kits (DAKO Co, USA) for the S-100 protein and the Cytokeratin were used and the following resulting were obtained. Acinic cells of the normal salivery gland were negative for both cytokeratin and S-100 protein. The intercalated duct cells were weakly positive for cytokeratin and S-100 protein. The normal myoepithelial cells scattered around the acini and the intercalated ducts were positive only S-100 protein. In contrast, the striated duct were positive only for cytokeratin. In plemorphic adenoma, the S-100 protein positive cells were found in solid sheets of tumor cells, in chondromyxoid areas and in areas of spindle-cell stroma as well as in the outer layer of the tubular structures. Only the inner lining of the tubules were positive for cytokeratin. In basal cell adenoma, the stromal spindle cells were strongly positive for S-100 protein and the epithelial cells weakly positive. When tubules were present within the epithelial sheets, the inner most lining cells were positive for cytokeratin. The peripheral palisaded tumor cells were negative for both substances. By immunostaining of the adenoid cystic carcinoma, S-100 protein containing cells were found focally scattered independently on the variety of histologies. The lining cells of true cystic structure were positive for cytokeratin. Immunostaining of the mucoepidermoid carcinoma demostrated that the squamous cells and the tubular epithelial cells contained cytokeraitn, whereas only a few intermediate cells were positive for S-100 protein. In Warthin's tumor there were no S-100 protein positive cells, although basally located epithelial cells of the papillae were positive for cytokeratin. These findings suggest that salivary gland tumors other than the Warthin's tumor arise from myoepithelial cells or reserve cells having dual potentiality differentating into myoepithelial and intercalcated duct cells.
3.Buerger's Disease of Paratesticular Tissue: A case report.
Soo Im CHOI ; So Young JIN ; Chan Il PARK
Korean Journal of Pathology 1988;22(4):462-466
We report a case of Buerger's disease manifested by a scrotal mass, in view of its rarity. A tender bean sized mass was palpated in the left scrotum of a 34 year-old male heavy smoker, who had a history of right pain two years ago which subsided spontaneously. The left testis with the paratesticular tissue was excised. Vessels of the spermatic cord and epididymis showed microscopic changes of Buerger's disease. The involved arteries and veins revealed a predominantly subacute pattern with granulomatous inflammation and Langhans' type giant cells within the thrombi.
Male
;
Humans
4.Extrahepatic Biliary Atresia.
The Korean Journal of Hepatology 2004;10(3):233-236
No abstract available.
Bile Ducts, Extrahepatic/*pathology
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Biliary Atresia/*pathology
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Female
;
Humans
;
Infant, Newborn
;
Liver/pathology
5.Nonalcoholic Steatohepatitis.
The Korean Journal of Hepatology 2006;12(3):455-459
No abstract available.
Aged
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Fatty Liver/epidemiology/*etiology/pathology
;
Female
;
Hepatitis/epidemiology/*etiology/pathology
;
Humans
;
Insulin Resistance
;
Metabolic Syndrome X/*complications/metabolism
;
Prevalence
;
Prognosis
;
Risk Factors
6.Recent Update of Pathology of the Pancreatic Neuroendocrine Tumor.
Korean Journal of Medicine 2011;80(4):371-377
Pancreas is an endocrine organ as well as an exocrine one. The pancreatic neuroendocrine tumor (PNET) is an epithelial tumor with features of endocrine differentiation. Its incidence is progressively increasing now. Because the prognosis of PNET is much better than that of ductal adenocarcinoma, the precise diagnosis and proper treatment is more important than ever. Recently World Health Organization (WHO) and American Joint Committee on Cancer (AJCC) published the new WHO 2010 classification and the unified staging system of the PNET unlike the other gastrointestinal tract. Here, recent update of pathology of PNET will be discussed with their basic morphologic characteristics and essential points in the pathology report.
Adenocarcinoma
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Chromogranin A
;
Gastrointestinal Tract
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Incidence
;
Joints
;
Neuroectodermal Tumors, Primitive
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Neuroendocrine Tumors
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Pancreas
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Prognosis
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World Health Organization
7.The Effect of Long-term Steroed Therapy combined with Azathioprine in Henoch-Schonlein Nephritis.
Kyoung Sang MOON ; So Young JIN ; Eun Mi KIM
Journal of the Korean Society of Pediatric Nephrology 1998;2(2):118-124
We describe cytologic findings of two cases of pilomatrixoma which had been cytologically misdiagnosed as suspicious malignant and malignant lesions in 35 year-old and 22 year-old females who presented a palpable neck mass. The cytologic smears showed many basaloid cells with a high nuclear-cytoplasmic ratio, nuclear hyperchromatism and prominent nucleoli, keratinized squamous cells with pyknotic nuclei, foreign body giant cells, and chronic inflammatory cells in necrotic background. Retrospective view of this aspiration smear revealed that these findings were characteristic features of pilomatrixoma, and the evenly distributed chromatin pattern as well as the lack of nuclear pleomorphism were considered to be the differential points from malignant neoplasm. Pilomatrixoma is a benign neoplasm which should be included in differential diagnosis if the fine needle aspiration cytologic smear of a neck mass or subcutaneous mass of any site showed these features.
Female
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Humans
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Diagnosis, Differential
8.Fatty Liver.
The Korean Journal of Hepatology 2006;12(1):112-115
No abstract available.
Liver/pathology
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Humans
;
Fatty Liver/*pathology
9.Familial Primary Biliary Cirrhosis in Sisters.
The Korean Journal of Hepatology 2004;10(1):73-77
No abstract available.
Adult
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Bile Ducts/pathology
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Female
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Humans
;
Liver Cirrhosis, Biliary/*genetics/pathology
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Middle Aged
10.Inflammatory Pseudotumor of the Liver.
The Korean Journal of Hepatology 2005;11(1):90-93
No abstract available.
Female
;
Granuloma, Plasma Cell/*pathology
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Humans
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Liver/*pathology
;
Liver Diseases/*pathology
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Middle Aged