2.Edwards Syndrome: an autopsy case.
So Young JIN ; Woo Hee JUNG ; Chang Ho HONG
Korean Journal of Pathology 1986;20(3):343-348
Edwards syndrome is first introduced by Edwards and characterized by facial anomalies, multiple cardiovascular, gastrointestinal, urogenital, and skeletal malformations. It results from triplication of part or all of chromosome 18 in some or all of the patient's cells. It has an incidence of 1 in 4,500 live births or less and short life expectancy. Recently we experienced a case of 3-day-old female new born infant with this syndrome. Post mortem examination showed progeric face with prominent occiput, large flabby ears, microphthalmia, and micrognathia, bilateral clenched hands with flexion contraction of middle fingers, and bilateral rockerbottom feet. Internal examination revealed horseshoe kidney, esophageal atresia with tracheoesophageal fistula, two accessory spleens, and multiple cardiac anomalies. A trisomy 18 was confirmed by the cytogenetic study.
Infant
;
Male
;
Female
;
Infant, Newborn
;
Humans
;
Incidence
3.Epidural Butorphanol Reduces the Side Effects from Epidural Morphine after Cesarean Section.
Dong Gi JANG ; Won Young CHANG ; So Young YOON ; Kyung Bae KIM
Korean Journal of Anesthesiology 1997;33(2):297-303
BACKGROUND: Epidural morphine has side effects, especially pruritus, nausea, and vomiting. Butorphanol has been added in studies to reduce these side effects in post cesarean patients. The purpose of this study was to evaluate the side effects and analgesic efficacy when a combination of epidural morphine and butorphanol was administered in patients having combined local anesthetic and opioid epidural infusion. METHODS: Sixty patients having epidural anesthesia for cesarean section were randomly divided into two groups. Group M (n=30) received a bolus of 0.25% bupivacaine 4 ml, morphine 2 mg, and saline 0.75 ml, whereas group B (n=30) received a bolus of 0.25% bupivacaine 4 ml, morphine 2 mg, and butorphanol 1.5 mg (0.75 ml). Continuous epidural infusion was done by Two-day Infusor containing either 0.25% bupivacaine 75 ml, morphine 5 mg, and saline 20 ml in group M or 0.25% bupivacaine 75 ml, morphine 5 mg, butorphanol 4 mg (2 ml), and saline 18 ml in group B. We compared the side effect and analgesic effect of group M to those of group B for 2 days. RESULTS: The incidence of pruritus and vomiting were reduced significantly in group B (p<0.05). There were no significant differences between both groups in the incidence of nausea or other side effects as well as no differences in analgesic effect. CONCLUSIONS: We conclude that the addition of butorphanol to morphine in combined local anesthetic and opioid epidural infusion for postoperative analgesia decreases the occurrence of pruritus and vomiting without significant increase of other side effects and adverse effect on analgesia.
Analgesia
;
Anesthesia, Epidural
;
Bupivacaine
;
Butorphanol*
;
Cesarean Section*
;
Female
;
Humans
;
Incidence
;
Infusion Pumps
;
Morphine*
;
Nausea
;
Pregnancy
;
Pruritus
;
Vomiting
4.Preoperative Evaluation on Geriatric Patients .
Young So KIM ; Young Sil KIM ; Chang Jae KWON
Korean Journal of Anesthesiology 1980;13(2):232-238
We have analysed 72 cases of geriatric patients over 70 year of age who underwent anesthesia in our Aospital from Jan. 1970 to May 1979 and the results were as follows; 1) Male patients were more than female(1.05: 1). (Male, 37 cases(51.4%) and female, 35cases (48. 6%). 2) By ASA classification, physical status was class II in 32 cases, E II in 24 cases, III in 12 cases, E III in 2 cases and IV in 2 eases. 3) The number of the patients of general surgery department(46.63%) was highest. 4) Preoperative problems were cardiovascular diseases including hypertension (11cases) and LVH(25 cases), arrhythmia(6cases), tachycardia(4cases), RBBB(2cases) and bradycardia (2 cases) in EKG. 5) Preoperative pulmonary disease including pulmonary tbc(14 cases), chronic bronchitis (6 cases), and emphysema(4 cases) was revealed in the chest PA. 6) There was no mortality during the operative or postoperative period.
Anesthesia
;
Bradycardia
;
Bronchitis, Chronic
;
Cardiovascular Diseases
;
Classification
;
Electrocardiography
;
Female
;
Humans
;
Hypertension
;
Lung Diseases
;
Male
;
Mortality
;
Postoperative Period
;
Thorax
5.CT Findings of the Brain Damages Resulting from the High Voltage Electric Injuries.
Young Keun KIM ; So Eun KIM ; Hyang Yi SHIM ; Shin Hyung LEE ; Chang Joon LEE
Journal of the Korean Radiological Society 1994;30(2):231-234
PURPOSE: The purpose of this study is to evaluate the CT features and pathogenesis of the electric brain injuries. MATERIALS AND METHODS: We reviewed the CT scans of 3 patients injured by high-voltage electricity. We evaluated the findings early and delayed periods in each patients. RESULTS: The early CT findings were diffuse brain edema, scalp swelling, and focal hemorrhagic contusion. The findings of delayed period were cerebral infarction, pneumocephalus, brain abscess, and pneumatocele. CONCLUSION: CT was useful to correlate the pathogenesis and variable features of electric brain injuries.
Brain Abscess
;
Brain Edema
;
Brain Injuries
;
Brain*
;
Cerebral Infarction
;
Contusions
;
Electric Injuries*
;
Electricity
;
Humans
;
Pneumocephalus
;
Scalp
;
Tomography, X-Ray Computed
6.The Korean Journal of Cytopathology: From Foundation to Unification with the Korean Journal of Pathology.
Korean Journal of Pathology 2009;43(1):1-3
No abstract available.
7.Effects of Aroma Hand Massage on Pain, State Anxiety and Depression in Hospice Patients with Terminal Cancer.
Journal of Korean Academy of Nursing 2008;38(4):493-502
PURPOSE: The purpose of this study was to examine the effects of aroma hand massage on pain, state anxiety and depression in hospice patients with terminal cancer. METHODS: This study was a nonequivalent control group pretest-posttest design. The subjects were 58 hospice patients with terminal cancer who were hospitalized. Twenty eight hospice patients with terminal cancer were assigned to the experimental group (aroma hand massage), and 30 hospice patients with terminal cancer were assigned to the control group (general oil hand massage). As for the experimental treatment, the experimental group went through aroma hand massage on each hand for 5 min for 7 days with blended oil-a mixture of Bergamot, Lavender, and Frankincense in the ratio of 1:1:1, which was diluted 1.5% with sweet almond carrier oil 50 ml. The control group went through general oil hand massage by only sweet almond carrier oil-on each hand for 5 min for 7 days. RESULTS: The aroma hand massage experimental group showed more significant differences in the changes of pain score (t=-3.52, p=.001) and depression (t=-8.99, p=.000) than the control group. CONCLUSION: Aroma hand massage had a positive effect on pain and depression in hospice patients with terminal cancer.
Aged
;
Anxiety/*therapy
;
Aromatherapy
;
Boswellia/drug effects
;
Data Interpretation, Statistical
;
Depression/*therapy
;
Female
;
*Hospice Care
;
Humans
;
Male
;
Massage
;
Middle Aged
;
Neoplasms/*psychology/therapy
;
Oils, Volatile/therapeutic use
;
Pain/*therapy
;
Pain Measurement
;
Plant Oils/therapeutic use
;
Stress, Psychological
8.Epidemiology of preterm delivery.
Hye Sung PARK ; So Young LEE ; Myoung A LEE ; Chang Suh PARK ; Seung Jin CHO ; In Suh PARK
Korean Journal of Perinatology 1993;4(1):46-56
No abstract available.
Epidemiology*
9.Spontaneous Echo Contrast Mistaken for Left Ventricular Thrombus during Venoarterial Extracorporeal Membrane Oxygenation.
Seok In LEE ; So Young LEE ; Chang Hyu CHOI ; Kook Yang PARK ; Chul Hyun PARK
Korean Journal of Critical Care Medicine 2017;32(4):372-375
No abstract available.
Extracorporeal Membrane Oxygenation*
;
Thrombosis*
10.Factors Predictive of Response to Interferon Therapy in Chronic HCV Infection.
Yun Soo KIM ; So Young KWAN ; Dong Jin SUH ; Chang Hong LEE
The Korean Journal of Hepatology 1996;2(2):176-185
BACKGROUND/AIMS: Although interferon-a(IFNa) is currently the most effective antiviral agent for treating patients with chronic hepatitis C, its efficacy is not always reliable. Factors suggested to infruence outcome of IFN-a therapy for chronic hepatitis C are histological activity, level of viremia and HCV genotype, etc. The aim of this study was to determine the relationship between several pretreatment factors and response to IFN-a therapy in patients with chronic HCV infection. METHODS: Fifty-four patients with chronic HCV infection(47 with chronic hepatitis and 7 with liver cirrhosis) who received IFN-a(2a or 2b) therapy(3 6 MU, three times a week, for 3 12 months) were included. Level of serum HCV RNA(50 patients), HCV genotype(27 patients) and IgM anti- HCV(21 patients) during pretreatment period were assayed. RESULTS: Overall, 19(35%) subjects achieved sustained response(SR), 12(22%) had transient response(TR) and 23(43%) did not respond (nonresponse;NR). Mean age of patients with SR, TR and NR was 46+ 10, 51+ 7.5 and 54+ 9.7 years, respectively(p<0.05 between SR and NR). Among 30 patients with biopsy-proven chronic hepatitis, 13(43%) achieved SR;but only one(14%) in 7 patients with liver cirrhosis. Mean serum HCV RNA level(X10' copies/ml) was higher in nonresponders(7,7+ 13.0) compared with SR(2.3+ 2. 7) or TR(3.1+ 4.9), although statistically insignificant HCV genotyping in 27 patients revealed type la in 5(18.5%), 1b in 14(52%), 2a in 5(18.5%), 2b in 1(3.7%) and 4 in 2(7%), respectively. In non-1b patients, SR rate was significantly higher than 1b patients(69.2% vs. 21.4%, p=0.03). Although IgM anti-HCV was positive in 12(57%) among 21 patients studied, the positive rate and the titer of IgM anti-HCV was not significantly different in three groups. CONCLUSION: Our results suggest that in patients with chronic hepatitis C, infection with genotype 1b, old age, high serum HCV RNA level and the presence of cirrhosis would predict poor response to IFN therapy.
Fibrosis
;
Genotype
;
Hepatitis C, Chronic
;
Hepatitis, Chronic
;
Humans
;
Immunoglobulin M
;
Interferons*
;
Liver
;
Liver Cirrhosis
;
RNA
;
Viremia