1.Assessment of Nutritional Adequacy of Gimbap Sold in Convenience Stores Focused on Protein and Mineral Content
So-Yun KIM ; Seong-Hee YOON ; Yun-A LEE ; Mi-Kyeong CHOI
Journal of the Korean Dietetic Association 2023;29(2):73-85
This study examined the nutritional information using the nutrition labels of gimbap sold at convenience stores and evaluated nutritional adequacy compared to dietary reference intakes for Korean adolescents. Thirty gimbaps (triangular gimbaps and regular gimbaps according to the main ingredients of vegetables, fish, and meat) were purchased at five convenience stores of different brands with many stores in Korea. The food and nutrition labels of the gimbaps were investigated, and nine minerals were analyzed using inductively coupled plasma–mass spectrometry (ICP-MS). The average price of gimbap was 1,906.7 won, and average energy was 292.0 kcal, and the protein content was 15.5% of the recommended intake for Korean male adolescents aged 15∼18 years. The mineral content ranged from 6.9% for zinc to 39.0% for selenium. Except for sodium and selenium, the energy, protein, and mineral content did not meet 1/3 of dietary reference intakes for adolescents. For the index of nutritional quality (INQ), calcium and zinc were the lowest in the triangular and regular gimbap, respectively. The INQ of potassium was significantly higher in triangular gimbap with vegetables. The content and INQ of selenium were in regular gimbap with fish, and the zinc INQ was in regular gimbap with meat. Overall, gimbap sold in convenience stores has a high sodium content, and the contents of energy, protein, and minerals, except selenium, are insufficient for a single meal.
2.Carotid Artery Stenting in Patients With Takayasu's Arteritis:Early and long-term follow-up results.
Wook Bum PYUN ; Young Sup YOON ; Kyung Jin PARK ; So Young KIM ; Seung Yun CHO ; Won Heum SHIM
Korean Circulation Journal 2000;30(5):592-598
Takayasu's arteritis is a chronic inflammatory disease of unknown etiology involving the aorta, major branches of aorta, and pulmonary arteries and leads either stenosis and occlusion of the involved artery or aneurysm formation or both. The clinical course and prognosis are variable according to two major prognostic factors, ie, complications and the pattern of the past clinical course, as well as by ESR. Though the aggressive medical and surgical treatment are required for patients with a major complication and a progressive course, surgical reconstruction entails a high incidence of suture line complications including stenosis or dilatation. Moreover all the vascular lesions are amenable for vascular surgery. Initial reports revealed excellent results of percutaneous transluminal angioplasty (PTA) in patients with Takayasu's arteritis. However the suboptimal results and restenosis have been the main limitations of the PTA. Stenting has some benefits for early elastic recoil of the fibrotic vessels and restenosis as in other large vessels in Takayasu's arteritis or atherosclerosis. We report early and long-term results of two cases of carotid stenting in patients with symptomatic carotid stenosis and Takayasu's arteritis, which revealed variable angiographic results according to clinical courses and recommend that stenting in Takayasu's arteritis may be another treatment modality in inactive Takayasu's arteritis.
Aneurysm
;
Angioplasty
;
Aorta
;
Arteries
;
Atherosclerosis
;
Carotid Arteries*
;
Carotid Stenosis
;
Constriction, Pathologic
;
Dilatation
;
Follow-Up Studies*
;
Humans
;
Incidence
;
Prognosis
;
Pulmonary Artery
;
Stents*
;
Sutures
;
Takayasu Arteritis
3.Multiple Biliary Papillomatosis: A case report.
Pan Ho YANG ; Byung Jun SO ; Kwon Mook CHAE ; Ki Jung YUN ; Kwon Ha YOON
Journal of the Korean Surgical Society 1999;57(3):446-450
Multiple biliary papillomatosis involves an epithelial field change of the intrahepatic and extrahepatic portions of the biliary tree. Pathologically it is benign, occasionally with dysplasia, but the clinical behavior is regarded as having a low-grade malignant potential. Such malignancy is rare but the prognosis is poor if it is impossible to remove the tumor completely. Here, we report one case of multiple biliary papillomatosis in the biliary tree.
Biliary Tract
;
Papilloma*
;
Prognosis
4.On the 10th Anniversary of the Korean Neonatal Network
So Yoon AHN ; Hye Young SONG ; Yun Sil CHANG ;
Neonatal Medicine 2023;30(1):1-9
The Korean Neonatal Network (KNN), which is celebrating its 10th anniversary, currently has more than 100 staff and researchers from >70 neonatal intensive care units nationwide in Korea. More than 85% to 90% of the population of very low birth weight infants in Korea are registered yearly, and more than half are followed up for up to 3 years at the KNN. A total of >19,000 cases have been accumulated through a strict data quality management process of the KNN. Based on this, >100 research projects have been proposed, >70 peer-reviewed papers have been published in leading international journals, and the cornerstone of the quality improvement project has been launched. In addition, we recently expanded the number of subjects for registration to very premature infants <32 weeks of age and continue to provide essential evidence data for establishing national health policies, such as linking with government policy projects of the Ministry of Health and Welfare for preterm infants. In such manner, the KNN is confident to be successfully and actively moving toward reaching the ultimate goal of standardizing neonatal intensive care and management of preterm infants in Korea by providing essential data for national health policy establishment along with quality improvement through evidence-based interactive data.
5.Combination Therapy by Tissue-Specific Suicide Gene and Bevacizumab in Intramedullary Spinal Cord Tumor
So-Jung GWAK ; Lihua CHE ; Yeomin YUN ; Minhyung LEE ; Yoon HA
Yonsei Medical Journal 2020;61(12):1042-1049
Purpose:
Malignant gliomas are aggressive spinal cord tumors. In this study, we hypothesized that combination therapy using an anti-angiogenic agent, bevacizumab, and hypoxia-inducible glioblastoma-specific suicide gene could reduce tumor growth.
Materials and Methods:
In the present study, we evaluated the effect of combination therapy using bevacizumab and pEpo-NI2-SV-TK in reducing the proliferation of C6 cells and tumor growth in the spinal cord. Spinal cord tumor was generated by the injection of C6 cells into the T5 level of the spinal cord. Complexes of branched polyethylenimine (bPEI)/pEpo-NI2-SV-TK were injected into the spinal cord tumor. Bevacizumab was then administered by an intraperitoneal injection at a dose of 7 mg/kg. The anti-cancer effects of combination therapy were analyzed by histological analyses and magnetic resonance imaging (MRI). The Basso, Beattie and Bresnahan scale scores for all of the treatment groups were recorded every other day for 15 days to assess the rat hindlimb strength.
Results:
The complexes of bPEI/pEpo-NI2-SV-TK inhibited the viability of C6 cells in the hypoxia condition at 5 days after treatment with ganciclovir. Bevacizumab was decreased in the cell viability of human umbilical vein endothelial cells. Combination therapy reduced the tumor size by histological analyses and MRI. The combination therapy group showed improved hind-limb function compared to the other groups that were administered pEpo-NI2-SV-TK alone or bevacizumab alone.
Conclusion
This study suggests that combination therapy using bevacizumab with the pEpo-NI2-SV-TK therapeutic gene could be useful for increasing its therapeutic benefits for intramedullary spinal cord tumors.
6.A Case Report of Hajdu-Cheney Syndrome.
Eun Jin HAN ; Jun Il MUN ; So Yeon AN ; Yun Jung JUNG ; Ok Hwa KIM ; Yoon Sok CHUNG
Endocrinology and Metabolism 2010;25(2):152-156
Hajdu-Cheney syndrome (HCS) is a rare skeletal dysplasia that is characterized by acroosteolysis of the distal phalanges, distinctive craniofacial and skull changes, dental abnormalities and generalized osteoporosis. The clinical and radiologic characteristics are variable and these characteristics progress with age. This syndrome shows autosomal dominant inheritance with sporadic cases. The genetic defects or molecular pathogenesis of HCS are still unknown. We experienced a case of Hajdu-Cheney syndrome in a 20-year-old man who had generalized osteoporosis with multiple non-traumatic spine compression fractures. He had acroosteolysis of the hands and feet, wormian bones in the skull, facial dysmorphism (mid-facial flattening, micrognathia and bushy eyebrows), a high arched palate, malocclusion and short dental alveolar processes. HCS was diagnosed based on the clinical and radiologic evidence. For the differential diagnosis, we excluded the other possible causes of the acroosteolysis and wormian bones, including hyperparathyroidism, osteogenesis imperfecta, hypophosphatemia and mandibuloacral dysplasia. The specific treatment of HCS is unknown, but case reports with bisphosphonate treatment have been reported.
Acro-Osteolysis
;
Alveolar Process
;
Diagnosis, Differential
;
Foot
;
Fractures, Compression
;
Hajdu-Cheney Syndrome
;
Hand
;
Humans
;
Hyperparathyroidism
;
Hypophosphatemia
;
Malocclusion
;
Osteogenesis Imperfecta
;
Osteoporosis
;
Palate
;
Skull
;
Spine
;
Wills
;
Young Adult
7.A Case of Recurrent Bacterial Meningitis and Mucocele After Cranial Trauma.
So Yeon YOON ; Sung Su JEON ; Sung Dong CHOI ; Seung Yun CHUNG ; Byung Kyu SUH ; Jin Han KANG
Korean Journal of Infectious Diseases 1998;30(6):579-585
Recurrent bacterial meningitis can be caused by acquired or congenital anatomic defects, infection, or alterations in immune mechanism. Intracranial anatomical defects possibly combined with trauma can be the major cause of recurrent bacterial meningitis. Mucocele is a chronic, expansile and cyst-like lesion of the paranasal sinuses, most frequently found in the frontal sinus containing sterile mucoid secretions. Secondary infection of a mucocele may create a pyocele. Although pathogenesis of a primary mucoceles remains uncertain, causatives factors of secondary mucoceles have been suggested to include chronic inflammation, trauma, allergy and obstructing tumors. We experienced a case of recurrent bacterial meningitis with frontal sinus mucocele, which might be secondary to cranial trauma.
Coinfection
;
Frontal Sinus
;
Hypersensitivity
;
Inflammation
;
Meningitis, Bacterial*
;
Mucocele*
;
Paranasal Sinuses
8.Stem Cell Therapy for Neonatal Disorders: Prospects and Challenges.
Yun Sil CHANG ; So Yoon AHN ; Sein SUNG ; Won Soon PARK
Yonsei Medical Journal 2017;58(2):266-271
Despite recent advances in neonatal medicine, neonatal disorders, such as bronchopulmonary dysplasia and intraventricular hemorrhage in preterm neonates and hypoxic ischemic encephalopathy in term neonates, remain major causes of mortality and morbidities. Promising preclinical research results suggest that stem cell therapies represent the next breakthrough in the treatment of currently intractable and devastating neonatal disorders with complex multifactorial etiologies. This review focuses primarily on the potential role of stem cell therapy in the above mentioned neonatal disorders, highlighting the results of human clinical trials and the challenges that remain to be addressed for their safe and successful translation into clinical care of newborn infants.
Bronchopulmonary Dysplasia
;
Hemorrhage
;
Humans
;
Hypoxia-Ischemia, Brain
;
Infant, Newborn
;
Mesenchymal Stromal Cells
;
Mortality
;
Stem Cells*
9.The Establishment of the Korean Neonatal Network (KNN).
Yun Sil CHANG ; So Yoon AHN ; Won Soon PARK
Neonatal Medicine 2013;20(2):169-178
Although, recently in Korea, it has been apparent that declining total birth rate in face of rapidly aging population and rapid increasing birth rate for high-risk infants such as preterm infants, mortality rate of premature infants is still higher than that of other developed countries and the significant morbidities including cerebral palsy or development delay is high among survived patients. Thus, the substantial socio-economic burden caused by high risk infants became a substantial problem to us. To improve the survival rate and to decrease major morbidities of high risk infants, Korean Neonatal Network (KNN) was established by Korean Society of Neonatology with the support from Korea Centers for Disease Control and Prevention and begins an official operation with a declaration for launching on April 15th, 2013. With base project of national prospective registry of very low birth weight infants, KNN would be an infrastructure for active and productive multi-center research for quality improvement of neonatal intensive care units (NICU) and development of Korean-style guideline or strategy for NICU management. In this review, we describe the background, purpose, progress, expected outcomes and future plans of the KNN.
Aging
;
Birth Rate
;
Centers for Disease Control and Prevention (U.S.)
;
Cerebral Palsy
;
Delivery of Health Care
;
Developed Countries
;
Evidence-Based Medicine
;
Humans
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Infant, Very Low Birth Weight
;
Critical Care
;
Intensive Care Units, Neonatal
;
Korea
;
Neonatology
;
Quality Improvement
;
Survival Rate
10.Successful desensitization of a patient with albumin hypersensitivity.
So Yoon JUNG ; Yun Jung CHOI ; Seung Hyun LEE ; Hye Ryun KANG ; Dong In SUH
Allergy, Asthma & Respiratory Disease 2017;5(2):117-120
There have been few cases of albumin hypersensitivity reported, and there is limited information on this condition. When a patient is anaphylactic to a certain drug and no alternative drug is available to treat the underlying condition, desensitization is a reasonable option and can be performed successfully to treat the patient. A standard 12-step, 3-solution rapid desensitization protocol allows the safe readministration of a medication after certain types of immediate hypersensitivity. However, we demonstrated that a new 10-step, 1-solution desensitization protocol using antihistamine and leukotriene receptor antagonist as premedications, which was effective and safe in a patient with hypersensitivity. We report a 13-year-old boy with Gorham-stout syndrome who was presented with newly acquired albumin anaphylaxis and successfully treated with the 10-step rapid drug desensitization protocol.
Adolescent
;
Anaphylaxis
;
Desensitization, Immunologic
;
Drug Hypersensitivity Syndrome
;
Humans
;
Hypersensitivity*
;
Hypersensitivity, Immediate
;
Male
;
Premedication
;
Receptors, Leukotriene