A Histologic finding of the Cutis marmorata telangiectatica congenita( CMTC) is non-specific, but dilated capillaries and increased number of vessels are often observed. Capillary hemangioma, mostly represented by strawberry nevus, may show various clinical manifestations. We report a case of Cutis marmorata telangiectatica congenita, which may be an unusual clinical presentation of capillary hemangioma.
Capillaries* ; Fragaria ; Hemangioma, Capillary* ; Nevus

BACKGROUND: Epinephrine itself interacts with adrenergic receptors to block pain transmission pathways. Intrathecal co-administration of morphine and epinephrine results in a near maximal increase in the nociceptive threshold. This study was designed to investigate the influence of different dosages of epinephrine on the postoperative pain relief through intrathecal morphine in lower extremity surgery. METHOD: Thirty patients, ASA physical status I or II, undergoing orthopedic surgery of lower extremities were selected and randomly divided into two groups as follows: Group I (n=15); bupivacaine, morphine 0.2 mg with epinephrine 0.12 mg. Group II (n=15); bupivacaine, morphine 0.2 mg with epinephrine 0.2 mg. With patients lateral in the decubitus position, a 25-gauge spinal needle was introduced into the subarachnoid space. Patients were turned to the supine position, and sensory levels were checked by pin-prick tests at the midclavicle level , and the degree of motor block by Bromage scale every 5 minutes. The two segment regression time was measured every 20 minutes. During the postoperative day and the second day, their analgesic effects were evaluated by use of the visual analogous scale (0~10). The side effects were also evaluated. RESULTS: There were no difference between both groups in sensory level and two-segment regression time. Motor block in 5, 10, 15 minutes was more intense in group II. Also, there were no significant difference in the analgesic effects and the incidence of side effects, such as nausea or pruritus. CONCLUSION: There were no significant dose effects of epinephrine added to intrathecal morphine for postoperative pain relief undergoing lower extremities surgery.
Analgesia* ; Bupivacaine ; Epinephrine* ; Humans ; Incidence ; Lower Extremity ; Morphine* ; Nausea ; Needles ; Orthopedics ; Pain, Postoperative ; Pruritus ; Receptors, Adrenergic ; Subarachnoid Space ; Supine Position

No abstract available.
Hyperpigmentation* ; Lichen Planus*

No abstract available.
Hyperpigmentation* ; Lichen Planus*

Most renal carcinomas are thought to originate from the epithelial cells of proximal convoluted tubules in the renal cortex. Collecting duct carcinoma is a recently recognized histological variety of renal cell carcinoma considered to arise from the epithelium of the collecting ducts. It is important to distinguish the collecting duct carcinoma from ordinary renal cell carcinoma, because which has an aggressive clinical course with early metastasis and death. But in patients, the natural course of the disease and its response to treatment have not been clearly established. Herein we report a case of collecting duct carcinoma of kidney in 38-year-old woman who had generalized edema and left flank dull pain. The preoperative diagnosis was left renal cell carcinoma on physical examination and radiologic finding, and left radical nephrectomy was done.
Adult ; Carcinoma, Renal Cell* ; Diagnosis ; Edema ; Epithelial Cells ; Epithelium ; Female ; Humans ; Kidney* ; Neoplasm Metastasis ; Nephrectomy ; Physical Examination

PURPOSE: The aim of this study was to investigate the effect of the maternal hypertension on the lipid peroxidation and antioxidant status of the newborn rat lung. METHODS: We used adult female SHR(essential hypertension, 1b, A, 6-8 weeks), Sprague-Dawley white rats as a model of hypertensive dams. Breeding was accomplished by allowing female and male rats to cohabit overnight. The animals were allowed to spontaneously deliver at term(21.5d). The pups delivered from the hypertensive dams grouped into HBP group. Control group consisted of the pups delivered from normal dams. The content of malondialdehyde(MDA) and activity of superoxide dismutase(SOD) and glutathione(GSH) in the lung tissues were analysed at birth and 24 hours later in both groups. RESULTS: The body weight of the HBP group was significantly lower than the control group at birth. At birth and 24 hours after birth, MDA content and SOD activity were significantly increased in the lung tissues of HBP group compared to control group. There were no significant differences in GSH activity between the two groups. After 24 hours, the elevated MDA value was significantly decreased, and SOD activity was significantly elevated in HBP group but there were no significant changes in the MDA value, SOD or GSH activity in the control group. CONCLUSION: These results support the possibility that maternal hypertension during pregnancy is associated with an increased lipid peroxidation and that compensatory activation of antioxidant system works in the fetal rat lung.
Adult ; Animals ; Body Weight ; Breeding ; Female ; Glutathione ; Humans ; Hypertension* ; Infant, Newborn* ; Lipid Peroxidation* ; Lung* ; Male ; Malondialdehyde ; Parturition ; Pregnancy ; Rats* ; Rats, Sprague-Dawley ; Superoxide Dismutase ; Superoxides

Dermatitis neglecta (unwashed dermatosis) presents as pigmented hyperkeratotic plaques with adherent scales which clinically resembles psoriasis. This condition is the result of avoiding washing the affected areas, so the lesions are characteristically resolved with normal washing or with gentle wiping from an alcohol swab. We report a 29-year-old man who presented with an asymptomatic hyperkeratotic scaly plaque on umbilicus. A skin biopsy was done under the clinical impression of psoriasis. During skin biopsy, gentle swabbing with H2O2 and saline gauze was done. The patient revisited our clinic 10 days after the skin biopsy and the hyperkeratotic lesion had cleared. Histologic examination showed orthokeratotic hyperkeratosis and anastomosing rete ridges. There has been no previous report of dermatitis neglecta with histologic confirmation, and so this case could be the first report to provide the histologic characteristics of dermatitis neglecta. Because this condition might be overlooked and underdiagnosed, recognizing its existence and cause are important to avoid unnecessary biopsies and potentially aggressive therapeutic measures.
Adult ; Biopsy ; Dermatitis ; Humans ; Psoriasis ; Skin ; Umbilicus ; Weights and Measures

Congenital myotonic dystrophy (CMD) which is transmitted in an autosomal-dominant manner, can also be observed in newborns born to asymptomatic parents who have a myotonic dystrophy type 1 or premutation allele, especially from the mother. A mother with myotonic dystrophy could be subfertile and the pregnancy could be complicated with the risk of a preterm birth. Newborns with CMD may demonstrate symptoms such as hypotonia and poor motor activity, as well as respiratory and feeding difficulties. Additionally, CMD has a high mortality rate at birth. Detection of the signs and symptoms during pregnancy is helpful for a prenatal diagnosis of CMD in cases where the family history is not known.
Alleles ; Genetic Counseling ; Humans ; Infant, Newborn ; Mortality ; Mothers ; Motor Activity ; Muscle Hypotonia ; Myotonic Dystrophy* ; Parents ; Parturition ; Postpartum Period ; Pregnancy ; Premature Birth ; Prenatal Diagnosis

Sjogren's syndrome (SS) is an autoimmune disorder primarily affecting the salivary and lacrimal glands. In addition, extra-glandular manifestations involving the lungs, liver, kidneys, pancreas, skin and central nervous system were reported in patients with SS. These extra-glandular manifestations are not rare in adult patient, but are very rare in pediatric SS. Renal manifestations are relatively common in adult SS, but are rarely reported in childhood SS. We experienced a girl with primary SS manifested with nephrogenic diabetes insipidus and renal tubular acidosis.
Acidosis, Renal Tubular ; Adult ; Central Nervous System ; Child ; Diabetes Insipidus ; Diabetes Insipidus, Nephrogenic ; Humans ; Kidney ; Lacrimal Apparatus ; Liver ; Lung ; Pancreas ; Sjogren's Syndrome ; Skin

Actinomycosis is a chronic suppurative and granulomatous bacterial infection most commonly presenting as an abscess, soft tissue swelling, or mass in the cervicofacial region. Although the organisms often invade soft tissues through damaged oral mucosa, actinomycosis presenting acutely as a superficial oral ulcer is extremely rare. We report a case of actinomycosis in a 6-year-old boy who presented a painful ulcer on the right buccal mucosa. Histopathologic examination showed sulfur granules and granulation tissue with mixed inflammatory infiltrate in the dermis. The granules contained numerous Gram-positive filamentous organisms consistent with actinomycosis. We propose that actinomycosis should be kept in mind in the diagnosis of oral ulcerations.
Abscess ; Actinomycosis* ; Bacterial Infections ; Child* ; Dermis ; Diagnosis ; Granulation Tissue ; Humans ; Male ; Mouth Mucosa ; Oral Ulcer* ; Sulfur ; Ulcer