PURPOSE: To determine the clinical and mammographic characteristics of primary lymphoma of the breast. MATERIALS AND METHODS: The clinical and mammographic records of five patients (six breasts; bilateral involvement in one patient) with histologically-proven lymphoma of the breast were retrospectively reviewed. RESULTS: All patients had complained of a palpable tender mass with relatively rapid growth over a period of about 3 months. In five cases, the mass was located in the right breast and in one case in the left. Mammography revealed diffuse increased opacity of the entire breast in three cases, a homogeneous well-defined mass in one, multiple well-defined masses in one, and ill-defined lobulated opacity in one. Skin thickening and architectural distortion was seen in one case, and axillary lymphadenopathy in two. In no case was microcalcification and nipple retraction seen. CONCLUSION: In primary breast lymphoma, mammographic finding are non-specific. When a breast grows rapidly and is tender, however, and mammography shows a relatively large well defined mass and associated axillary lymphadenoapathy, the possibility of primary lymphoma should be considered.
Breast* ; Humans ; Lymphatic Diseases ; Lymphoma* ; Mammography ; Nipples ; Retrospective Studies ; Skin

PURPOSE: The aim of this study was to evaluate the clinical significance of 24 hour pH monitoring in the pediatric patients with recurrent vomiting or regurgitation. METHODS: We performed 24 hour pH monitoring on 87 pediatric patients with recurrent vomiting or regurgitation using GastrograpH with glass electrode. The pathologic GER was determined by the reflux index (RI). RIs>10% were considered positive in patients <1 year of age, whereas RIs of <5% were positive in other age groups. We evaluated the mean and standard deviation of the reflux parameters between physiologic and pathologic GER groups, and also compared the reflux indices of each group with respect to time zones of the day. RESULTS: Pathologic GER was found in 32 of 87 patients (36.8%), and the age incidence included 32.5% in infants <6 months old, 13.3% in infants aged 6 months-1 year old, 61.5% in children aged 1~2 years old, 14.3% in children aged 2~3 years old and 66.7% in children >3 years old. In physiologic GER patients, the RI was 3.7+/-2.9% for the patients <1 year old (group A), and 1.8+/-1.5% for those > or =1 year old (group B) which was statistically significant between the 2 age groups (p=0.02). The number of long refluxes more than 5 minutes was significantly increased (p=0.03) in group A (1.7+/-1.9) than in group B (0.8+/-1.0). The duration of the longest reflux was significantly longer (p=0.007) in group A (604+/-551 sec) than in group B (275+/-296 sec). In pathologic GER patients, the RI was 17.7+/-11.6% for the patients <1 year old and 7.8+/-2.9 for those > or =1 year old. The number of long refluxes of more than 5 minutes were 8.9+/-4.6 and 3.2+/-1.8, and the duration of the longest reflux were 1955+/-2190 sec and 1093+/-706 sec for each age group. In both physiologic and pathologic GER patients, there was no significant difference of RI among the time zones of the day. CONCLUSION: Pathologic GER was found in 36.8% of patients. There was significant difference of RI between those <1 year old and those > or =1 year old in physiologic GER patients. There was no significant difference of RI among the time zones of the day in both pathologic and physiologic groups. In our study, the frequency of pathplogic GER was too much higher in age group of 1~2 years old (61.5%) than in group of 6 months-1 year old (13.3%), which means that further study is needed to determine the pathologic criteria of RI (Vandenplas criteria is >5%) in the age group of 1~2 years old.
Child* ; Electrodes ; Esophageal pH Monitoring* ; Gastroesophageal Reflux ; Glass ; Humans ; Hydrogen-Ion Concentration ; Incidence ; Infant ; Vomiting*

No abstract available.

No abstract available.
Cryopreservation* ; Humans* ; Spermatozoa*

Nutcracker syndrome (NCS) is a disease caused by compression of the left renal vein between the superior mesenteric artery and the abdominal aorta. Immunoglobulin A (IgA) nephropathy (IgAN) is characterized by the predominance of IgA deposits in the glomerular mesangial area. Hematuria and proteinuria can be present in both diseases, and some patients can be concurrently diagnosed with NCS and IgAN; however, a causal relationship between the two diseases has not yet been clarified. Here, we report two pediatric cases of NCS combined with IgAN. The first patient presenting with microscopic hematuria and proteinuria was diagnosed with NCS at the initial visit, and the second patient was later diagnosed with NCS when proteinuria worsened. Both patients were diagnosed with IgAN based on kidney biopsy findings and treated with angiotensin-converting enzyme inhibitors and immunosuppressants. A high index of suspicion and timely imaging or biopsy are essential for the proper management of NCS combined with glomerulopathy.

BACKGROUND: Tinea pedis and onychomycosis is a common disease and the proportion of that in the aged has been significantly increased. Although there have been many reports about tinea pedis and onychomycosis, very few studies about that in the aged have yet been conducted. OBJECTIVE: The purpose of this study is to evaluate the prevalence and clinical features of tinea pedis and onychomycosis in the aged. METHODS: One hundred twenty-six persons over 65 years old who visited the Daegu public aged welfare center (57 persons), Seongju public health center (38 persons) and hospitalized Yeungnam University Yeongcheon hospital (31 persons) from September 20, 2005 to October 7, 2005 were examined clinically and evaluated tinea pedis and onychomycosis. Their clinical lesions were confirmed by KOH preparation and fungal culture. RESULT: Among 126 examined, 62 persons (49.2%) had tinea pedis and/or onychomycosis. Prevalence of the tinea pedis and/or onychomycosis of male (53.2%) was higher than that of female (38.2%). There was no difference in the prevalence between the living area or age. Most common clinical type of tinea pedis was hyperkeratotic type (n=21/66.7%). All patients with onychomycosis were distal subungual onychomycosis. In this study common underlying disease was hypertension (22.6%), diabetes mellitus (8.1%) and cerebrovascular accident (8.1%), however, there was no correlation between underlying diseases and the prevalence of tinea pedis and/or onychomycosis. Among 87 persons, 21 strains of dermatophytes were isolated. They were 19 strains of Trichophyton(T.) rubrum, 2 strains of T. mentagrophytes. The rate of previous treatment for this problem was 32.6%. CONCLUSIONS: All this finding suggest that the prevalence of tinea pedis and/or onychomycosis in the aged was high and they did not know about the disease. Tinea pedis and/or onychomycosis in the aged could become a source of infection and complication. Therefore, it is necessary to educate them and support to treat the disease effectively. Future studies including a large number of examinee and correlation of other diseases will be needed.
Arthrodermataceae ; Daegu ; Diabetes Mellitus ; Female ; Humans ; Hypertension ; Male ; Onychomycosis* ; Prevalence* ; Public Health ; Stroke ; Tinea Pedis* ; Tinea*

PURPOSE: There is no reported evidence for an anthropometric index that might link obesity to men's sexual health. We evaluated the ability of an anthropometric index and the symptom scores of five widely used questionnaires to detect men's health problems. We determined the predictive abilities of two obesity indexes and other clinical parameters for screening for lower urinary tract symptoms and sexual dysfunction in middle-aged men. MATERIALS AND METHODS: A total of 1,910 middle-aged men were included in the study. Participants underwent a detailed clinical evaluation that included recording the symptom scores of five widely used questionnaires. The participants' body mass index and waist-to-hip ratio were determined. Serum prostate-specific antigen, urinalysis, testosterone, estimated glomerular filtration rate, evaluation of metabolic syndrome, and transrectal ultrasonography were assessed. RESULTS: By use of logistic regression analysis, age and total prostate volume were independent predictors of lower urinary tract symptoms. Metabolic syndrome was the only significant negative predictive factor for chronic prostatitis symptoms. Age and metabolic syndrome were independent predictive factors for erectile dysfunction. Waist-to-hip ratio had a statistically significant value for predicting erectile dysfunction. CONCLUSIONS: Our data showed that total prostate volume is a significant predictor of lower urinary tract symptoms, and central obesity has predictive ability for erectile dysfunction. Metabolic syndrome was the only significant negative predictive factor for chronic prostatitis-like symptoms. The management of correctable factors such as waist-to-hip ratio and metabolic syndrome may be considered preventive modalities against the development of men's health problems.
Aging ; *Body Mass Index ; Erectile Dysfunction/*diagnosis ; Humans ; Logistic Models ; Lower Urinary Tract Symptoms/diagnosis ; Male ; *Men's Health ; Metabolic Syndrome X/*physiopathology ; Middle Aged ; Obesity ; Organ Size ; Prognosis ; Prostate/*ultrasonography ; Prostate-Specific Antigen/blood ; Prostatitis/*diagnosis ; Testosterone/blood ; Ultrasound, High-Intensity Focused, Transrectal ; *Waist-Hip Ratio

PURPOSE: There has been an epidemic of measles in Korea since 2000. Therefore, we analyze the epidemiologic haracteristics of measles in Gwangju Metropolitan City. METHODS: We reviewed the epidemiologic investigation records and laboratory data of the measles patients reported in Gwangju Metropolitan City from January 1st 2000. RESULTS: 1) Demographic characteristics: Totally, 3,392 cases were surveyed and 3,300 cases were enrolled (3,300/3,392, 97.3%). Fifty-four percents of the patients were male (1,771/3,300) and forty-six percents of the patients were female (1,529/3,300). Average age of the patients was 8.20 years (8.20 5.56 years). Forty-seven percents of the patients were reported in the interval from November 2000 to December 2000 (1,582/3,298, 47.9%). 2) Clinical manifestations of the patients: Common symptoms of measles patients were fever (3,300/3,300, 100.0%), skin rash (3,068/3,300, 93.0%), cough (2,889/3,300, 87.5%), rhinorrhea (1,883/3,300, 57.1%), headache (1,445/3,300, 43.8%), conjunctival injection (1,182/3,300, 35.8%), and oral thrush (832/3,300, 25.2%). Among the patients, 250 patients had complications (250/3,300, 7.6%) and most of them were respiratory complications (220/250, 88.0%). 3) Vaccination: Eighty-six percent of the enrolled patients answered the question about vaccination (2,854/3,300, 86.4%); 808 patients were not taken a shot (808/2854, 28.3%), 1,762 patients received one dose (1,762/2,854, 61.7%), and 284 patients received additional dose (284/2,854, 9.9%). 4) Laboratory data: Laboratory confirmed cases were 780 patients (780/3,300, 23.6%); 603 cases were confirmed serologically, 185 cases were positive in PCR, and virus was isolated in 6 cases. Genetic sequencing of the isolated viruses was clade H1 and closely related to that of China. CONCLUSION: Therefore, adequate surveillance and maintenance of high coverage rate of the vaccination would be the crucial factors to eradicate measles
Candidiasis, Oral ; China ; Cough ; Exanthema ; Female ; Fever ; Gwangju ; Headache ; Humans ; Korea ; Male ; Measles* ; Polymerase Chain Reaction ; Vaccination

PURPOSE: Urologists occasionally experience some cases of voiding failure after transurethral resection of prostate (TURP). Preoperative and postoperative factors attributable to acute urine retention (AUR) after catheter removal in post-TURP patients were evaluated and analyzed to determine the causative factors for AUR. MATERIALS AND METHODS: From June 2004 to May 2008, a total of 172 patients who underwent TURP due to symptomatic benign prostatic hyperplasia (BPH) were divided into the AUR group (n=21) and the control group (n=151). The AUR group was defined as patients with voiding difficulty within 24 hours and whose residual urine volume was above 400 ml after catheter removal. The control group was defined as patients without AUR. Age, duration of symptoms, International prostate symptom score (IPSS), Quality of life score (QoL), uroflowmetry, post-void residual urine volume, preoperative serum prostate specific antigen (PSA) level, preoperative prostate volume, resected prostate volume, rate of prostate resection [resected prostate volume/preoperative prostate volume x 100], operative time and duration of catheter were retrospectively analyzed to identify which of these were the factors related with AUR after catheter removal in post-TURP patients. RESULTS: Preoperative prostate volume was higher (90.7+/-50.4 vs 64.4+/-32.7, p=0.002) and rate of prostate resection was lower (38.8+/-8.1 vs 50.5+/-12.4, p<0.001) in AUR group compared to control group. And age, duration of symptoms, IPSS, QoL, uroflowmetry, post-void residual urine volume, preoperative serum PSA level, resected prostate volume, operative time and duration of catheter were not statistically significant in both groups. The multivariate analysis subsequently showed that preoperative prostate volume (p=0.010, OR=1.040) and rate of prostate resection (p=0.001, OR=0.901) were independent factors related with AUR after catheter removal in post-TURP patients. CONCLUSIONS: The incidence of AUR after catheter removal was higher in post-TURP patients with high preoperative prostate volume and low rate of prostate resection. Therefore the surgeon's effort to increase the rate of prostate resection, especially in patients with large prostate volume, may lower the incidence of postoperative AUR.
Catheters ; Humans ; Hyperplasia ; Incidence ; Multivariate Analysis ; Operative Time ; Prostate ; Prostate-Specific Antigen ; Prostatic Hyperplasia ; Quality of Life ; Retention (Psychology) ; Retrospective Studies ; Transurethral Resection of Prostate ; Urinary Retention

PURPOSE: Some patients develop side effects from theophylline even at low serum concentrations. We designed a prospective study to evaluate the side effects of theophylline. METHODS: A Prospective, controlled trial study was conducted. The low-dose group received an intravenous continuous aminophylline dose of 5 mg/kg/day on the first day and subsequently 10 mg/kg/day on the following two days. The usual-dose group received 10 mg/kg/day for three days and the control group received normal saline for three days. Heart rate, respiratory rate, serum concentration of theophylline, and four adverse events (irritability, sleep disturbance, jitter, and vomiting) were checked at the time of admission and at 2, 12, 24, 48, and 72 h after the start of aminophylline infusions. RESULTS: Nine patients out of 37 in the low-dose group and six of 21 in the usual-dose group dropped out because of uncontrolled irritability. The serum concentrations of theophylline in dropouts (3.68+/-1.93 ig/mL) and participants (4.47+/-2.45 ig/mL) were not significantly different. Irritability was a more frequent side effect in the usual-dose group at 12 h, but there was no difference between the low-dose and usual-dose groups in terms of vomiting, sleep disturbance, and jitter. Most of the severe adverse effects were observed in children below two years of age. CONCLUSION: Some patients dropped out regardless of the initiating aminophylline dose, especially patients under the age of two years.
Aminophylline ; Asthma ; Child ; Heart Rate ; Humans ; Patient Dropouts ; Prospective Studies ; Respiratory Rate ; Theophylline ; Vomiting