Most of the gastric outlet obstruction symptoms like vomiting and abdominal distension were caused by congenital anatomical abnormality in a neonate. Abnormal structures associated with congenital gastric outlet obstruction have been categorized by its site and extent of obstruction. We report one case of persisting vomiting in a premature infant caused by serosal fibrous band in gastric outlet lesion, excluded from the category of congenital gastric outlet obstruction.
Fibrosis ; Gastric Outlet Obstruction* ; Humans ; Infant, Newborn ; Infant, Premature ; Vomiting

PURPOSE: The prevalence of childhood obesity has increased dramatically. It is important to know about life style and dietary habits of the obese children because the treatment of childhood obesity focuses on using behavioral modification techniques. We aimed to develop a questionnaire for the purpose of providing convenient and useful guidance to pediatricians who evaluate and treat obese children. METHODS: Previously developed questionnaire was given to 94 obese children and their parents who had visited clinic for obese children and adolescents. We analyzed response rates on questions and reliability between children and their parents. RESULTS: The response rates on questions were somewhat high. Agreement of paired questions of both parents and children was also moderately high (63~92%). It is acceptable to complete questions by either parents or children alone. Items for hours of playing video games or computer, maternal job, kind of consuming beverage and food outside home were added. CONCLUSION: We concluded that some questions are not needed to be given to both parents and their children. It would be better to have parents record life style of their children and to have children record their food intake with physical activity outside home.
Adolescent ; Beverages ; Child* ; Eating ; Food Habits ; Health Behavior* ; Humans ; Life Style ; Motor Activity ; Obesity ; Parents ; Pediatric Obesity ; Prevalence ; Surveys and Questionnaires* ; Video Games

PURPOSE: There is a paucity of evidence about prognosis after a first febrile seizure in older children. We investigated the prognosis and potential risk factors associated with subsequent unprovoked seizures in children who had experienced a first febrile seizure over 6 years of age, which we termed as late-onset febrile seizure. METHODS: We included all patients six years or older who presented to the emergency department with a febrile seizure between 2009 and 2015. Clinical data was collected by chart review and parents were contacted for information on seizure progress. We used the Cox proportional-hazards model and Kaplan-Meier analysis for evaluating the risk factors for subsequent unprovoked seizures. RESULTS: Of 247 patients, we excluded 168 children who had a history of epilepsy, unprovoked, or febrile seizure and who were followed-up for period less than six months. Overall, 79 patients were classified as having had a first late-onset febrile seizure. During follow-up of 34.9±25.7(mean±SD) months, unprovoked seizure recurred in 7 of 79 patients (9%). The cumulative probability of seizure recurrence was 4% at 6 months, 6% at 1 year and 9% at 2 years. Clinical variables predictive of subsequent unprovoked seizures were not proved. CONCLUSION: This is the first multicenter study focusing on prognosis after a late-onset febrile seizure in children six years or older. The percentage of subsequent unprovoked seizure in patients with late-onset febrile seizure was 9% at 2 years of follow-up. Prospective follow-up study with longer duration is warranted.
Child ; Emergency Service, Hospital ; Epilepsy ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Parents ; Prognosis* ; Prospective Studies ; Recurrence ; Risk Factors ; Seizures ; Seizures, Febrile*

The association of malignancy with glomerulonephritis is well known. The most frequent observed renal lesions associated with malignancy are the membranous glomerulonephritis on carcinoma and minimal change nephrotic syndrome on Hodgkin's disease. Recently, IgA nephropathy associated with liver disease, connective tissue disease, gastrointestinal disease, dermatologic disease, hematologic disease and malignancy were reported. But the relationship between malignancy and IgA nephropathy is not clearly resolved. Here we report a case of IgA nephropathy associated with early gastirc cancer. Successful treatment of early gastric cancer didn't completely resolve the IgA nephropathy but led to a significant reduction of hematuria and loss of proteinuria. Therefore we suggest that a certain association between IgA nephropathy and early gastric cancer can be made by studying the course of the disease.
Connective Tissue Diseases ; Gastrointestinal Diseases ; Glomerulonephritis ; Glomerulonephritis, IGA* ; Glomerulonephritis, Membranous ; Hematologic Diseases ; Hematuria ; Hodgkin Disease ; Immunoglobulin A* ; Liver Diseases ; Nephrosis, Lipoid ; Proteinuria ; Stomach Neoplasms*

Spinal muscular atrophy (SMA) type I is a common severe autosomal recessive inherited neuromuscular disorder that has been mapped to chromosome 5q11.2-13.3. The survival motor neuron (SMN) gene, a candidate gene, is known to be deleted in 96% of patients with SMA type I. Presently, PCR and single strand conformation polymorphism (PCR-SSCP) analyses have been made possible for application to both archival slides and paraffin-embedded tissues. Archival materials represent valuable DNA resources for genetic diagnosis. We applied these methods for the identification of SMN gene of SMA type I in archival specimens for the prenatal diagnosis. In this study, we performed the prenatal diagnosis with chorionic villus sampling (CVS) cells on two women who had experienced neonatal death of SMA type I. DNA extraction was done from archival slide and tissue materials and PEP-PCR was performed using CVS cells. In order to identify common deletion region of SMN and neuronal apoptosis-inhibitory protein (NAIP) genes, cold PCR-SSCP and PCR-restriction site assay were carried out. Case 1 had deletions of the exons 7 and 8, and case 2 had exon 7 only on the telomeric SMN gene. Both cases were found to be normal on NAIP gene. These results were the same for both CVS and archival biopsied specimens. In both cases, the fetuses were, therefore, predicted to be at very high risk of being affected and the pregnancy were terminated. These data clearly demonstrate that archival slide and paraffin-embedded tissues can be a valuable source of DNA when the prenatal genetic diagnosis is needed in case any source for genetic analysis is not readily available due to previous death of the fetus or neonate.
Chorionic Villi Sampling ; Diagnosis ; DNA ; Exons ; Female ; Fetus ; Genes, vif ; Humans ; Infant, Newborn ; Motor Neurons ; Muscular Atrophy, Spinal* ; Neuronal Apoptosis-Inhibitory Protein ; Polymerase Chain Reaction ; Pregnancy ; Prenatal Diagnosis* ; Spinal Muscular Atrophies of Childhood*