OBJECTIVE: To investigate the prevalence of obesity and sleep disorders and the association between them among children in Lanzhou, China. METHODS: The stratified cluster random sampling method was used to select 3 283 primary school students in four districts of Lanzhou of Gansu province. Physical examination and sleep questionnaire were conducted to screen out the children who met the criteria for sleep disorders or obesity as subjects. Among the 3 283 children, 200 healthy children without sleep disorders or obesity were enrolled as the control group. RESULTS: The prevalence rate of obesity among the 3 283 children was 5.76% (189/3 283). Among these 189 obese children, 80 (42.3%) had sleep disorders. The prevalence rate of sleep disorders was 16.24% (533/3 283), and the prevalence rate of obesity among the children with sleep disorders was 24.6% (131/533). Snoring was the most common sleep disorder in obese children. The prevalence rate of obstructive sleep apnea hypopnea syndrome was 45% (36/80) among obese children with sleep disorders. The obese children had a significantly higher prevalence rate of sleep disorders than the children with normal body weight [42.3% (80/189) vs 20% (40/200), P<0.01]. CONCLUSIONS There is a close relationship between obesity and sleep disorders in children in Lanzhou, China.
Body Mass Index ; Child ; China ; Humans ; Obesity ; complications ; Sleep Wake Disorders ; complications ; Snoring

Adult ; Humans ; Male ; Palate ; surgery ; Postoperative Complications ; Pulmonary Embolism ; etiology ; Snoring ; surgery ; Uvula ; surgery

BACKGROUND AND OBJECTIVES: Surgeons have tried various methods of adenoidectomy from the conventional transoral ad- enoidectomy using curettes or adenotomes to the newly developed transnasal endoscopic adenoidectomy using microdebriders. However, surgeons still face a great difficulty in achieving complete adenoidectomy due to the unfavorable anatomic structure and a narrow operating field. This study aims to introduce and try to establish a better way of performing transoral endoscopic adenoidectomy using microdebriders. MATERIALS AND METHODS: Thirty patients who underwent transoral endoscopic adenoidectomy using rnicrodebriders were prospectively randomized. Skull lateral radiographs and endoscopic photographs were obtained to analyze the surgical outcome of transoral endoscopic adenoidectomy using a microdebrider. RESULTS: There were no specific postoperative complications such as hemorrhage or infection. Nasal obstruction disappeared within 7 postoperative days, and mouth breathing and snoring were simultaneously improved. CONCLUSION: Transoral endoscopic adenoidectomy using a microdebrider can be considered as one of the most effective methods for more complete adenoidectomy to relieve nasal obstruction and to reduce mouth breathing and snoring.
Adenoidectomy* ; Hemorrhage ; Humans ; Mouth Breathing ; Nasal Obstruction ; Postoperative Complications ; Prospective Studies ; Skull ; Snoring

We reported a case of children's OSAHS caused by the huge fibrolipoma in pharynx nasalis. The patient was a 10-years-old child who went to the hospital with the chief complaint of "Snoring and mouth breathing during sleep for 10 years". Imaging tests found one huge tumor in pharynx nasalis before the operation. The tumor was resected totally. The postoperative pathological diagnosis was fibrolipoma. No recurrence was noted during the follow-up visit one year postoperatively. The clinical features, diagnosis, treatment, pathology and prognosis were reviewed herein.
Child ; Humans ; Lipoma ; complications ; surgery ; Neoplasm Recurrence, Local ; Pharynx ; pathology ; Prognosis ; Sleep Apnea, Obstructive ; etiology ; Snoring

BACKGROUND AND OBJECTIVES: Uvulopalatopharyngoplasty remains the most common surgical procedure performed as a treatment for obstructive sleep apnea syndrome. But, the authors believe that the surgical technique has some of the following limitations: a relatively low success rate, possible complications and the lack of a consensus on the palatal resection margin. In this study, we present a modified surgical technique and its clinical experiences. SUBJECTS AND METHOD: Twelve patients with snoring and obstructive sleep apnea/hypopnea were included in this study between September 2004 and April 2005. We divided the patients into two groups according to the resection margin of the uvula. And we defined the palatal incision margin as a palatoglossal line and tried a suture remodeling of the neopharynx. RESULTS: Abnormal breathing cessation (apnea/hypopnea) during sleep disappeared in all patients. There was no residual snoring in 10 patients (83.3%) but 2 patients (16.7%) complained of some residual snoring. The group with less than half resection of the uvula during surgery had a neouvula formed and could maintain a naturally shaped velopharynx. These patients had low incidence of postoperative complications such as severe scar formation and globus sensation. CONCLUSION: We recommend the palatoglossal line as an ideal incision margin for the uvulopalatopharyngoplasty and the preservation of the neouvula.
Cicatrix ; Consensus ; Humans ; Incidence ; Palate, Soft ; Postoperative Complications ; Respiration ; Sensation ; Sleep Apnea, Obstructive ; Snoring ; Sutures ; Uvula

The clinical manifestation included snoring and mouth breathing for 2 years, repeated coughing and shortness of breath in action for more than 1 year. Physical examination of oral cavity showed tonsils were in grade III. The endoscopy showed 2/3 of postnaris were blocked by the adenoids. The preoperative ultrasonic cardiogram revealed the right atrial and right ventricular dilatation, pulmonary artery widened. The preoperative polysomnography (PSG) showed apnea-hypopnea index (AHI) was 28.5 events an hour, and the lowest oxygen saturation (LSaO2) was 39%. The patient was diagnosed as severe obstructive sleep apnea hypopnea syndrome with pulmonary hypertension. The postoperative PSG showed the AHI was 11.7 events an hour, and the LSaO2 was 86%. The ultrasonic cardiogram at 5 months after surgery didn't show any abnormalities.
Adenoids ; pathology ; Child ; Cough ; Humans ; Hypertension, Pulmonary ; complications ; diagnosis ; Palatine Tonsil ; pathology ; Polysomnography ; Sleep Apnea, Obstructive ; complications ; diagnosis ; Snoring

OBJECTIVE: To explore the pathogenesis of abnormal behavior in children with obstructive sleep apnea-hypopnea syndrome (OSAHS). METHOD: The behavioral problems and C-reactive protein were measured in 40 children with OSAHS and 30 children with habitual snoring who underwent overnight Polysomnography, 40 cases of healthy children for the control group. RESULT: The ratio of abnormal behavior in OSAHS and habitual snoring children was significantly higher than that of the healthy control group, while no significant difference between the two groups. The content of C-reactive protein in OSAHS children (4.24 mg/L) was significantly higher than habitual snoring (2.76 mg/L) and healthy control group (1.27 mg/L); in habitual snoring children C-reactive protein was higher than in healthy control group. The content of serum C-reactive protein in OSAHS children accompanied by abnormal behavior (4.63 mg/L) was significantly higher than that without abnormal behavior (3.23 mg/L). The content of serum C-reactive protein content in habitual snoring children accompanied by abnormal behavior (3.63 mg/L) was significantly higher than that without abnormal behavior (1.76 mg/L). CONCLUSION OSAHS and habitual snoring children have more behavior problems. C-reactive protein levels are higher in children with OSAHS and habitual snoring, and the levels of C-reactive protein are related to the abnormal behavior in these children.
C-Reactive Protein ; analysis ; Child ; Child Behavior Disorders ; complications ; Child, Preschool ; Female ; Humans ; Male ; Polysomnography ; Sleep Apnea, Obstructive ; blood ; complications ; psychology ; Snoring ; blood ; complications ; psychology

OBJECTIVE: To explore the relationship between sleep respiratory events and hypoxemia following obstructive sleep apnea-hypopnea syndrome (OSAHS) and its clinical significance. METHOD: Forty-five patients suffered from snoring and suspected of sleep breathing disorders were measured by a Chinese version of Epworth Sleepiness Scale and tested by polysomnography all night long. Some ordinary polysomnographic parameters were recorded in all cases as well as the delay period of desaturation which means the duration from the beginning of sleep respiratory events to the beginning of the following desaturation. RESULT: Forty-five patients were all suffered from obstructive sleep respiratory events. The mean delay period of desaturation in group of middle OSAHS was longer than that in group of normal snorers (P<0.05) as well as mild OSAHS (P<0.05). The mean delay period of desaturation in group of severe OSAHS was much longer than that in group of normal snorers (P<0.01) as well as mild OSAHS (P<0.01). But there is no significant difference between normal snorers and patients with mild OSAHS (P>0.05), and the difference between patients with middle OSAHS and patients with severe OSAHS as well (P>0.05). The mean delay period of desaturation had a positive relationship with AHI (r = 0.608, P<0.01) and a negative relationship with lowest SaO2 (LSaO2) (r = - 0.543, P<0.01). The relationship between total scores of the 7 questions of Epworth sleepiness scale (ESS7) with the mean delay period of desaturation (r = 0.689, P<0.01) was significantly higher than that with AHI and LSaO2 (r = 0.486, P<0.01; r = - 0.422, P<0.01). CONCLUSION The delay period of desaturation is a sensitive parameter which describe oxygen desaturation following obstructive sleep respiratory events. The mean delay period of desaturation in group of middle and severe OSAHS was much longer than that in group of normal snorers as well as mild OSAHS. Furthermore, the mean delay period of desaturation has a closely relationship with AHI and LSaO2. And it was highly associated with ESS7 than AHI and LSaO2. Based on it, the mean delay period of desaturation may provide valuable information in evaluating the severity of the patients with OSAHS. It may evaluate the severity of daytime sleepiness better than AHI and LSaO2.
Adult ; Aged ; Female ; Humans ; Hypoxia ; etiology ; Male ; Middle Aged ; Polysomnography ; Sleep ; Sleep Apnea, Obstructive ; complications ; physiopathology ; Sleep Stages ; Snoring

BACKGROUND AND OBJECTIVES: Mitomycin-C is an antibiotic, antineoplastic agent that inhibits DNA and protein synthesis, and fibroblast proliferation. It has been successfully used in adjunction to glaucoma surgery, dacryocystorhinostomy, pterygium surgery, and middle meatal antrostomy. The purpose of this study is to evaluate the symptomatic improvement and the state of soft palate stenosis after intraoperative application of topical Mitomycin-C in surgical treatment of snoring. SUBJECTS AND METHOD: Forty-two patients (38 men, 4 women) undergoing laser-uvulopalatopharyngoplasty (Laser-UPPP) for snoring were included. The patients were operated on at the Inha University Hospital between May of 2003 and Oct. of 2004. The patients were divided into two groups in accordance with intraoperative application of topical Mitomycin-C in surgical treatment of snoring. The degree of snoring and apnea related symptoms and complication were evaluated using questionnaries preoperatively and postoperatively. We also evaluated and compared the degree of stenosis of soft palate postoperatively of each group. RESULTS: After Laser-UPPP, significant differences were seen in the pre & postoperative symptom score (snoring, apnea, daytime sleepiness) of each group, but no significant differences were observed between groups. There was a significant improvement in the degree of stenosis of soft palate in the group with intraoperative application of topical Mitomycin-C. Significant differences were seen in the postoperative complication score (nasal regurgitation, foreign body sensation) in the experimental group. CONCLUSION: Intraoperative topical application of Mitomycin-C can be used as a beneficial adjunct therapy in the surgical treatment of snoring.
Apnea ; Constriction, Pathologic ; Dacryocystorhinostomy ; DNA ; Fibroblasts ; Foreign Bodies ; Glaucoma ; Humans ; Male ; Mitomycin* ; Palate, Soft ; Postoperative Complications ; Pterygium ; Snoring*

BACKGROUND: We aim to explore the association between self-reported snoring and hypertension among adults aged 30-79 in Chongqing, China. METHODS: A total of 23,342 individuals aged 30-79 were included at baseline from August 2018 to January 2019, and the final sample size for the analysis was 22,423. Face-to-face interviews and physical examinations were conducted by trained investigators. Logistic regression was performed to study age-specific and gender-specific associations between snoring and hypertension. RESULTS: Frequent snoring was associated with the risk of hypertension for each age and gender group, and the frequency of snoring was positively correlated with the risk for hypertension. For the three age groups (< 45, 45-59, ≥ 60), compared with the non-snoring group, those who snore often had a 64.5%, 53.3%, and 24.5% increased risk of hypertension (< 45: OR = 1.65, 95%CI 1.34-2.02; 45-59: OR = 1.53, 95%CI 1.37-1.72; ≥ 60: OR = 1.25, 95%CI 1.09-1.42), respectively. For men and women, those who snore often had a 46.8% and 97.2% increased risk of hypertension, respectively, than the non-snoring group (men: OR = 1.47, 95%CI 1.33-1.63; women: OR = 1.97, 95%CI 1.75-2.23). CONCLUSIONS People who snore frequently should pay close attention to their blood pressure levels in order to achieve early prevention of hypertension, particularly for snorers who are female and aged under 45; importance should be attached to their blood pressure control.
Adult ; Aged ; China/epidemiology* ; Cross-Sectional Studies ; Female ; Humans ; Hypertension/etiology* ; Male ; Middle Aged ; Self Report ; Snoring/complications*