Sleep deprivation may cause accidents, and it has deteriorating effects on health. A measurement of postural steadiness by a portable and affordable Nintendo Wii Fit balance board can be used to quantify a person's alertness. At work, people are under the influence of their environment—often other people—that may affect their alertness. This work investigates whether sleep deprivation among people is “contagious,” as quantified by sway measures. We measured 21 volunteers' postural steadiness while alert and sleep deprived. During the measurements, a screen placed in front of the participants showed a footage of either alert or sleep-deprived faces. We found a significant difference between the day time and night time steadiness, but found no effect resulting from watching footage of sleep-deprived people. This finding shows that a posturographic sleepiness tester quantifies physiological sleep deprivation, and is insensitive to the influence of social factors.
Sleep Deprivation

The reciprocal interaction between sleep and pain has been reported by numerous studies. Patients with acute or chronic pain often complain of difficulty falling asleep, frequent awakenings, shorter sleep duration, unrefreshing sleep, and poor sleep quality in general. According to the majority of the experimental human studies, sleep deprivation may produce hyperalgesic changes. The selective disruption of slow wave sleep has shown this effect more consistently, while results after selective REM sleep deprivation remain unclear. Patients with chronic pain have a marked alteration of sleep structure and continuity, such as frequent sleep-stage shifts, increased nocturnal awakenings, decreased slow wave sleep (SWS), decreased rapid eye movement (REM) sleep, and alpha-delta sleep. Many analgesic medications can alter sleep architecture in a manner similar to the effects of acute and chronic pain, suppressing SWS and REM sleep.
Chronic Pain ; Humans ; Sleep Deprivation ; Sleep, REM

Sleep deprivation can be described as inadequate quantity or quality of sleep characterized by insufficient sleep duration, delayed sleep onset, and occurrence of napping episodes during the day. Sleep deprivation in animals and obstructive sleep apnea syndrome in human was reported to be associated with increased oxidative stress. Glycyrrizha glabra (licorice) is a medicinal plant known to be a highly efficacious medicinal herb with several pharmacological effects. Hence, the aim of this study was to demonstrate whether or not licorice root extract will regulate the imbalance between the reactive oxygen species and production of antioxidant enzymes in the brain of sleep deprived rats. Twenty - five 6-week-old male Wistar rats were randomly divided into five groups to undergo sleep deprivation and recovery for 5 days each. Group I (Control): Group II: sleep deprivation (SD); Group III: sleep deprivation and recovery (SD+SR) all received distill water (10ml/kg) orally; Group IV: sleep deprivation and licorice (SD+Lic), Group V: sleep deprivation, recovery with licorice (SD+SR+Lic) both received licorice (150mg/kg) orally once daily. MDA concentration among rats in Groups II (51%), III (46.7%) and IV (31.3%) were significantly higher when compared with control. Rats in Group III (20.5%), Group IV (24.6%) and Group V (30.8%) showed increased significant change in GSH concentration when compared with Group II. The concentration of CAT among rats in Group II was significantly lower than those rats in Group III (43.8%), Group IV (53.8%) and Group V (72.9%). These results clearly show that sleep deprivation significantly affects the oxidative status of rats. In conclusion, licorice root extract has ameliorative effect on the imbalance between the reactive oxygen species and production of antioxidant enzymes in the brain of sleep deprived rats.
Sleep ; Sleep Deprivation ; Oxidative Stress, Rats

PURPOSE: Korean adolescents have severe nighttime sleep deprivation and daytime sleepiness because of their competitive educational environment. However, daytime sleep patterns and sleepiness have never been studied using age-specific methods, such as the pediatric daytime sleepiness scale (PDSS). We surveyed the daytime sleepiness of Korean adolescents using a Korean translation of the PDSS. METHODS: We distributed the 27-item questionnaire, including the PDSS and questions related to sleep pattern, sleep satisfaction, and emotional state, to 3,370 students in grades 5-12. RESULTS: The amount of nighttime sleep decreased significantly with increasing age. During weekday nights, 5-6th graders slept for 7.95+/-1.05 h, 7-9th graders for 7.57+/-1.05 h, and 10-12th graders for 5.78+/-1.13 h. However, the total amounts of combined daytime and nighttime sleep during weekdays were somewhat greater, 8.15+/-1.12 h for 5-6th graders, 8.17+/-1.20 h for 7-9th graders, and 6.87+/-1.40 h for 10-12th graders. PDSS scores increased with age, 11.89+/-5.56 for 5-6th graders, 16.57+/-5.57 for 7-9th graders, and 17.71+/-5.24 for 10-12th graders. Higher PDSS scores were positively correlated with poor school performance and emotional instability. CONCLUSION: Korean teenagers sleep to an unusual extent during the day because of nighttime sleep deprivation. This negatively affects school performance and emotional stability. A Korean translation of the PDSS was effective in evaluating the severity of daytime sleepiness and assessing the emotional state and school performance of Korean teenagers.
Adolescent ; Humans ; Surveys and Questionnaires ; Sleep Deprivation

Drowsy driving is a major cause of automobile crashes which can lead to more serious injuries than other causes of traffic accidents. Here, we review the accumulated scientific evidences and legal decisions of drowsy driving in various countries. Also, we highlight recent institutional strategies and developing technologies for prevention of drowsy driving. To prevent drowsy driving, raising public awareness as well as collaboration of professionals in various fields are requisites.
Accidents, Traffic ; Automobiles ; Cooperative Behavior ; Sleep Deprivation ; Sleep Wake Disorders

OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) not only causes respiratory disturbances during sleep but also decreases the quality of nocturnal sleep through sleep fragmentation and sleep structure change. We aimed at comparing the changes in sleep fragmentation and structure between baseline (diagnostic) nocturnal polysomnography (NPSG) and nCPAP (nasal continuous positive airway pressure) titration trial. METHODS: One hundred and three patients with a baseline night of respiratory disturbance index (RDI) of 5 or greater and reduced RDI score during nCPAP titration night were retrospectively selected for the study. Sleep fragementation and sleep structure between baseline NPSG and the NPSG during nCPAP titration were compared. Sleep fragmentation index (SFI) was defined as the total number of awakenings and shifts to stage 1 sleep divided by the total sleep time in hour. SFI and other polysomnographic parameters were statistically compared between the two nights. RESULTS: SFI during baseline NPSG and nCPAP titration nights were 29.0+/-13.8 and 15.2+/-8.8, respectively, indicating a significant SFI decrease during nCPAP titration (t=9.7, p<0.01). SFI showed significant negative correlations with sleep efficiency (r=-0.60, p<0.01) and total sleep time (r=-0.45, p<0.01) and a positive correlation with RDI (r=0.28, p<0.01). CONCLUSION: Use of nCPAP, even during the titration, significantly decreases sleep fragmentation and improves sleep structure in OSAS patients. We suggest that SFI may be utilized as a measure of assessing OSAS severity and nCPAP efficacy.
Humans ; Polysomnography ; Retrospective Studies ; Sleep Apnea, Obstructive ; Sleep Deprivation

OBJECTIVES: Nurses working in a hospital operate in a special environment where patients require a 24-hour day service. In order to meet the need for manpower, nurses in the wards, ICU, and ER work in 3 shifts per day. This study was designed to evaluate their sleeping patterns and the factors that influence them. METHODS: The subjects were 114 female nurses working at a University Hospital in Kyungi-do. To evaluate their sleeping pattern, a survey containing 11 questions was used. Their were differentiated into insomnia, sleep deprivation, daytime sleepiness, and snoring. Statistical analysis was conducted with independent t test, chi-square test and analysis of covariance. RESULTS: A statistical difference was found between shiftworkers and nonshiftworkers, in terms of sleep initiation time (p<0.05). The occurrences of insomnia, sleep deprivation, daytime sleepiness and snoring differed between the two groups, but not significantly. CONCLUSIONS: Of the numerous factors affecting sleeping patterns, shiftwork has the most deteriorative effect.
Female ; Humans ; Sleep Deprivation ; Sleep Initiation and Maintenance Disorders ; Snoring

The sleep homeostatic response significantly affects the state of anesthesia. In addition, sleep recovery may occur during anesthesia, either via a natural sleep-like process to occur or via a direct restorative effect. Little is known about the effects of isoflurane anesthesia on sleep homeostasis. We investigated whether 1) isoflurane anesthesia could provide a sleep-like process, and 2) the depth of anesthesia could differently affect the post-anesthesia sleep response. Nine rats were treated for 2 hours with ad libitum sleep (Control), sleep deprivation (SD), and isoflurane anesthesia with delta-wave-predominant state (ISO-1) or burst suppression pattern-predominant state (ISO-2) with at least a 1-week interval. Electroencephalogram and electromyogram were recorded and sleep-wake architecture was evaluated for 4 hours after each treatment. In the post-treatment period, the duration of transition to slow-wave-sleep decreased but slow wave sleep (SWS) increased in the SD group, but no sleep stages were significantly changed in ISO-1 and ISO-2 groups compared to Control. Different levels of anesthesia did not significantly affect the post-anesthesia sleep responses, but the deep level of anesthesia significantly delayed the latency to sleep compared to Control. The present results indicate that a natural sleep-like process likely occurs during isoflurane anesthesia and that the post-anesthesia sleep response occurs irrespective to the level of anesthesia.
Anesthesia ; Animals ; Electroencephalography ; Homeostasis ; Isoflurane ; Rats ; Sleep Deprivation ; Sleep Stages

BACKGROUND/AIMS: Oral sodium phosphate has been shown to be effective and safe but causes intravascular volume contraction, changes in serum calcium and phopshate level, and sleep disturbance when given two doses every 12 hours. Because the evening dose is inconvenient for many patients, we gave single morning dose, and compared it with conventional 12-hour-split dose. METHODS: Sixty one patients drank 90 mL of sodium phosphate at 7:00 AM and 58 patients drank 45 mL of sodium phosphate at 7:00 PM and 7:00 AM respectively. RESULTS: There was no statistical difference in bowel cleansing between two groups (p=0.871). There was no significant difference in patient's tolerance and symptoms between two groups except sleep deprivation which was more frequent in the split dose group. None of the patients complained of postural dizziness or presyncope in both groups. Serum phosphate levels were increased and serum calcium levels were decreased after preparation in both groups, but patients showed no significant clinical symptoms such as tetany. CONCLUSION: This study suggests that giving a single morning dose of sodium phosphate is effective, well tolerated and safe in most patients for precolonoscopic cleansing, compared to conventional split dose of 12-hour interval.
Calcium ; Colonoscopy ; Dizziness ; Humans ; Sleep Deprivation ; Sodium* ; Syncope ; Tetany

The current working conditions of medical interns and residents in South Korea pose dangers to patient safety as well as to staff health. A national survey in 2014 showed that interns/residents worked an average of 93 hours per week. The prevalence of physical and verbal violence experienced by medical residents in the preceding 12 months was reported as 13.1% and 61.5%, respectively. Furthermore, sleep deprivation due to long working hours was strongly associated with a high risk of committing 'near miss errors'. An act to govern the working environment of interns/residents was established in 2015 and stipulates a maximum working hours of 88 hours per week. This is an important step toward improving patient safety and intern/resident health in South Korea.
Humans ; Korea ; Occupational Health ; Patient Safety* ; Prevalence ; Sleep Deprivation ; Violence