1.Oral treatment for obstructive sleep apnea syndrome.
Hu-Chun WAN ; Xue-Dong ZHOU ; Shu-Juan ZOU ; Song-Song ZHU ; Ya-Feng LIU ; Guang-Yao ZHOU ; Guang-Ning ZHENG ; Jia-Nong YANG ; Yong-Hong HE
West China Journal of Stomatology 2018;36(6):581-589
Obstructive sleep apnea syndrome (OSAS) is a common clinical disease with high incidence and low treating proportion, difficult evaluation, and complicated nosogenesis. OSAS can cause systematic impairments. Various treatment methods were applied in clinical setting with the tendency of cross-disciplinary promotion. Oral treatment plays an exceedingly important role in OSAS research and therapy. This study reports the oral treatment involving OSAS therapy.
Humans
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Sleep Apnea, Obstructive
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therapy
3.Diagnosis and treatment of sleep disordered breathing: an update.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(6):483-485
The sleep breathing disorders (SDB) include obstructive sleep apnea (OSA), central sleep apnea disorders, sleep related hypoventilation disorders, and sleep related hypoxemia disorder in international classification of sleep diseases 3rd edition (ICSD-3). Latest diagnosis criteria are introduced. Treatments, which target to Individual contributors, should be applied. Thus identification of the phenotype in patients with OSA is important. The methods of evaluation patients' arousal thresholds, loop gain as well as neuromyopathy in clinical setting are reported. Several new treatment strategies are developed and applied for OSA. Long term follow up and more data are needed for evaluation the outcomes of hypoglossal nerve stimulation, bariatric surgery as well as medicine as treatments for OSA.
Humans
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Sleep Apnea Syndromes
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diagnosis
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therapy
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Sleep Apnea, Central
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Sleep Apnea, Obstructive
4.Treatment-emergent central sleep apnea: a unique sleep-disordered breathing.
Jing ZHANG ; Le WANG ; Heng-Juan GUO ; Yan WANG ; Jie CAO ; Bao-Yuan CHEN
Chinese Medical Journal 2020;133(22):2721-2730
Treatment-emergent central sleep apnea (TECSA) is a specific form of sleep-disordered breathing, characterized by the emergence or persistence of central apneas during treatment for obstructive sleep apnea. The purpose of this review was to summarize the definition, epidemiology, potential mechanisms, clinical characteristics, and treatment of TECSA. We searched for relevant articles up to January 31, 2020, in the PubMed database. The prevalence of TECSA varied widely in different studies. The potential mechanisms leading to TECSA included ventilatory control instability, low arousal threshold, activation of lung stretch receptors, and prolonged circulation time. TECSA may be a self-limited disorder in some patients and could be resolved spontaneously over time with ongoing treatment of continuous positive airway pressure (CPAP). However, central apneas persist even with the regular CPAP therapy in some patients, and new treatment approaches such as adaptive servo-ventilation may be necessary. We concluded that several questions regarding TECSA remain, despite the findings of many studies, and it is necessary to carry out large surveys with basic scientific design and clinical trials for TECSA to clarify these irregularities. Further, it will be vital to evaluate the baseline demographic and polysomnographic data of TECSA patients more carefully and comprehensively.
Continuous Positive Airway Pressure
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Humans
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Lung
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Respiration
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Sleep Apnea, Central/therapy*
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Sleep Apnea, Obstructive
7.The current situation and future research area of therapeutic methods for pediatric obstructive sleep apnea syndrome.
Zhifei XU ; Yunxiao WU ; Xin NI
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2015;50(10):873-876
Child
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Humans
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Pediatrics
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methods
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Sleep Apnea, Obstructive
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therapy