Endoscopy ; Humans ; Myosarcoma ; diagnosis ; surgery ; Nasal Cavity ; Nose Neoplasms ; diagnosis ; surgery ; Paranasal Sinuses ; Skull Base ; Skull Base Neoplasms ; diagnosis ; surgery

Consensus Development Conferences as Topic ; Endoscopy ; Europe ; Humans ; Nose Neoplasms ; diagnosis ; surgery ; Skull Base Neoplasms ; diagnosis ; surgery

Osteoclastoma of the calvarial bone of membranous origin is a rare entity. This paper presents a case of osteoclastoma of the occipital bone and a brief review of literature.
Child ; Giant Cell Tumors/*diagnosis/surgery ; Human ; Male ; *Occipital Bone ; Skull Neoplasms/*diagnosis/surgery

Antigens, CD34 ; metabolism ; Craniotomy ; Diagnosis, Differential ; Follow-Up Studies ; Hemangiosarcoma ; metabolism ; pathology ; surgery ; Humans ; Male ; Middle Aged ; Skull ; pathology ; surgery ; Skull Neoplasms ; metabolism ; pathology ; surgery ; Vimentin ; metabolism

OBJECTIVE: To explore the diagnosis and treatment of lateral skull base tumors in children. METHOD: The clinical data of 8 patients with lateral skull base tumors were reviewed in a retrospective study. One had schwannoma of the trigeminal nerve, one had malignant melanoma, one had fibroma in temporal bone, one had chordoma, two had rhabdomyosarcoma, two had esthesioneuroblastoma. Of 8 patients, one case was treated with chemotherapy. The other 7 cases of benign or malignant tumors underwent surgery in different approaches. Four patients had pre-and postoperative chemotherapy. Three patients received postoperative chemotherapy. RESULT: The group patients had been followed up for 1-1.5 years and it was shown that there was no recurrence in 4 cases, while there was recurrence in 4 cases. One patient of chordoma died 5 months after surgery, the other 7 patients were alive at the time of analysis. Cerebrospinal fluid leak occurred in two patients who healed with management. Hearing loss occurred in one patient in the operated ear. One patient developed hoarseness. Two patients developed swallowing obstruction and healed 3-4 months after surgery. CONCLUSION Tumors in lateral skull base in children were rare, of which malignant tumors were more common compared to benign lesions. CT and MRI are helpful in evaluating extent of disease and preoperative planning. Surgery is the first choice of the treatment for lateral skull base tumors. Radiation therapy and chemotherapy could be used for malignant tumors preoperatively and postoperatively. Combined approach of temporal and infratemporal fossa is suitable for the surgery of those tumors involved temporal bone and middle or posterior cranial fossa as well as infratemporal fossa.
Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Retrospective Studies ; Skull Base Neoplasms ; diagnosis ; surgery

Although intracranial dural metastasis of Ewing's sarcoma is a very rare finding, its imaging characteristics are similar to those of its primary form in the central nervous system. Thus, this tumor must be considered in the differential diagnosis of extra-axial dural masses.
Adult ; Dura Mater/*pathology ; Female ; Humans ; Magnetic Resonance Imaging ; Sarcoma, Ewing's/diagnosis/*pathology/surgery ; Skull Neoplasms/diagnosis/*secondary/surgery ; Spinal Neoplasms/diagnosis/pathology/surgery ; Tomography, X-Ray Computed

BACKGROUNDVarious surgical approaches for the removal of sellar region lesions have previously been described. This study aimed to evaluate the reliability and safety of the frontolateral approach (FLA) to remove sellar region lesions.

METHODSWe presented a retrospective study of 79 patients with sellar region lesions who were admitted and operated by the FLA approach from August 2011 to August 2015 in Department of Neurosurgery of Beijing Tian Tan Hospital. We classified FLA into three types, compared the FLA types to the areas of lesion invasion, and analyzed operation bleeding volume, gross total resection (GTR) rate, visual outcome, and mortality.

RESULTSSeventy-nine patients were followed up from 2.9 to 50.3 months with a mean follow-up of 20.5 months. There were 42 cases of meningiomas, 25 cases of craniopharyngiomas, and 12 cases of pituitary adenomas. The mean follow-up Karnofsky Performance Scale was 90.4. GTR was achieved in 75 patients (94.9%). Two patients (2.5%) had tumor recurrence. No patients died perioperatively or during short-term follow-up. Three patients (3.8%) with craniopharyngioma died 10, 12, and 23 months, respectively, after surgery. The operative bleeding volume of this study was no more than that of the other approaches in the sellar region (P = 0.783). In this study, 35 patients (44.3%) had visual improvement after surgery, 38 patients (48.1%) remained unchanged, and three patients' visual outcome (3.8%) worsened.

CONCLUSIONSFLA was an effective approach in the treatment of sellar region lesions with good preservation of visual function. FLA classification enabled tailored craniotomies for each patient according to the anatomic site of tumor invasion. This study found that FLA had similar outcomes to other surgical approaches of sellar region lesions.

Adult ; Craniopharyngioma ; diagnosis ; surgery ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Meningioma ; diagnosis ; surgery ; Middle Aged ; Pituitary Neoplasms ; diagnosis ; surgery ; Retrospective Studies ; Skull Base ; pathology

OBJECTIVETo study the pathologic type, clinical manifestations and treatment of skull neoplasms.

METHODSA series of 119 patients with skull neoplasm were analyzed retrospectively with respect of clinical manifestations, radiologic features, treatment and prognosis.

RESULTS122 operations were done with 3 patients being operated twice. Complete resection was done 75 times, subtotal resection 24 times, partial resection 22 times and biopsy only once. Gross type: exophytic 43(36.1%), endophytic 27(22.7%) and mixed type 49 (41.2%). Among the 85 patients followed, 78.6% have recovered and are living well, 16.6% of patients are self-caring, 2 need others' help and 2 have died.

CONCLUSIONMost skull neoplasms require neurosurgical intervention. Surgical excision is able to confirm the diagnosis, slow down the progression of neurologic dysfunction, prolong the patients' lives and improve the cosmetic results.

Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Skull Neoplasms ; diagnosis ; pathology ; surgery

We report a rare case of petroclival craniopharyngioma with no connection to the sellar or suprasellar region. MRI and CT images revealed a homogenously enhancing retroclival solid mass with aggressive skull base destruction, mimicking chordoma or aggressive sarcoma. However, there was no calcification or cystic change found in the mass. Here, we report the clinical features and radiographic investigation of this uncommon craniopharyngioma arising primarily in the petroclival region.
Cranial Fossa, Posterior/*pathology/radiography/surgery ; Craniopharyngioma/*diagnosis/radiography/surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Pituitary Neoplasms/*diagnosis/radiography/surgery ; Skull Base Neoplasms/*diagnosis/radiography/surgery ; Tomography, X-Ray Computed

OBJECTIVETo discuss the early diagnosis and the treatment of chordoma in the jugular foramen area.

METHODSThree cases of chordoma in the jugular foramen area were diagnosis and reviewed retrospectively. The initial symptom was facial paralysis. Surgical removal was performed through the infratemporal fossa approach in 1 case, through petro-occipital approach in 2 cases. For repairing facial nerve defect, great auricular nerve was used in 1 case and facial-hypoglossal anastomosis was used in another 2 cases.

RESULTSThe tumor were totally removed in all 3 cases. The patients were follow-up for 6 months to 1 year and no recurrence was found. The function of facial nerve was II grade (House-Brackmann) in one patient and IV grade in another 2 patients. No complications occurred in 3 cases.

CONCLUSIONSAlthough chordoma originating from the jugular foramen area were extremely rare, it was possible to make early diagnosis through finding clinical feature and imaging methods. The final diagnosis depended on pathology. Generally, the different surgical approaches were used according to the size and position of the tumor. The classic infratemporal fossa approach for tumor removal and facial nerve reconstruction should be considered in the patients with chordoma around jugular foramen.

Adult ; Chordoma ; diagnosis ; surgery ; Female ; Glomus Jugulare ; pathology ; Humans ; Male ; Middle Aged ; Otologic Surgical Procedures ; Retrospective Studies ; Skull Base Neoplasms ; diagnosis ; surgery ; Young Adult