Alopecia areata is a common skin disease with diverse modalities of therapy. The eyebrows are one of the target sites of alopecia areata and may be the only affected site. We report our recent experiences of superficial cryotherapy with liquid nitrogen to promote eyebrow hair growth due to alopecia areata. According to our results, superficial cryotherapy of alopecia areata in eyebrows can be an effective mode of treatment.
Alopecia Areata* ; Alopecia* ; Cryotherapy* ; Eyebrows* ; Hair ; Nitrogen ; Skin Diseases

No abstract available.
Acrodermatitis*

No abstract available.
Acrodermatitis*

BACKGROUND: Alopecia areata (AA) is an autoimmune skin disease difficult to manage and treat. The pathogenesis of AA features a T-cell-associated autoimmune process, and systemic immunosuppressive therapy is prescribed widely for AA. OBJECTIVE: To evaluate the efficacy and tolerance of systemic low-dose methotrexate (LD-MTX) therapy in treatment of recalcitrant AA multiplex. METHODS: In a retrospective, non-controlled study, we evaluated 29 patients with recalcitrant AA treated with LD-MTX and assessed the therapeutic response according to severity of disease, disease duration, cumulative dose of MTX, and drug safety. RESULTS: MTX was administered twice weekly, and the mean maximum weekly dose was 14.48 mg. The response was A5 (regrowth=100.0%) in 14 (48.3%) patients and A4 (regrowth of 75%~90%) in 12 (41.4%) patients. Three patients had poor response to LD-MTX treatment (A2: n=2 [6.9%], A1: n=1 [3.4%]). All three of the patients showing a poor response had disease durations exceeding 24 months. Relapse was observed in 31% of patients with more than 75% regrowth. Common side-effects were elevated liver enzyme levels and gastrointestinal discomfort. CONCLUSION: LD-MTX appears to be an effective and well-tolerated treatment for recalcitrant AA multiplex.
Alopecia Areata* ; Alopecia* ; Humans ; Liver ; Methotrexate* ; Recurrence ; Retrospective Studies ; Skin Diseases

The eyebrows consist of thickened arches of skin, which bear numerous short, thick hairs directed obliquely to the surface. Alopecia areata is a nonscarring hair loss condition, which is considered to be an autoimmune disease. The patchy loss of hairs occurring in alopecia areata may not only involve the scalp, but also the eyebrows, making it a disfiguring disease. This condition almost always involves the scalp, so alopecia areata only involving the eyebrows is very rare. We report two cases of alopecia areata limited to the eyebrows without involving any other sites during the disease course in healthy girls.
Alopecia Areata* ; Alopecia* ; Autoimmune Diseases ; Eyebrows* ; Female ; Hair ; Humans ; Scalp ; Skin

Acrodematitis enteropathica is an uncommon disease due to zinc deficiency which is characterized by perioral and acral dermatitis, alopecia, and diarrhea. This disease typically presents in infants, either due to an autosomal recessive genetic disorder or after cessation of breastfeeding. Acquired adult-onset acrodermatitis enteropathica has rarely been reported so far. We report a case of a 38-year-old man who had a history of chronic alcohol intake and presented with severe acrodermatitis enteropathica. The patient was successfully managed with zinc supplement and supportive care.
Acrodermatitis* ; Adult ; Alopecia ; Breast Feeding ; Dermatitis ; Diarrhea ; Humans ; Infant ; Zinc*

Acanthosis nigricans is characterized by hyperpigmented, velvety thickening of the skin of any part of the body and frequently associated with internal malignancy, endocrine diseases and obesity. In children, systemic abnormality rarely occur in associated with prepubertal Acanthosis nigricans. We experienced a case of idiopathic Acanthosis nigricans, and made a brief review of literatures.
Acanthosis Nigricans* ; Child ; Endocrine System Diseases ; Humans ; Obesity ; Skin

No abstract available.
Blister ; Immunoglobulin A ; Linear IgA Bullous Dermatosis ; Skin Diseases ; Vancomycin

No abstract available.
Alopecia Areata* ; Alopecia*

No abstract available.
Alopecia Areata* ; Alopecia* ; Scalp*