1.Calcinosis Cutis at the Tarsus of the Upper Eyelid.
Ikhyun JUN ; Sung Eun KIM ; Sang Yeul LEE ; Gi Jeong KIM ; Jin Sook YOON
Korean Journal of Ophthalmology 2011;25(6):440-442
Calcinosis cutis involves the inappropriate deposition of calcium within the dermis layer of the skin, and is often associated with rheumatoid disease. A 42-year-old woman presented for evaluation of a hard palpable mass on the left upper eyelid. After everting the eyelid, a large papillomatous mass with a broad base was identified on the superior area of the tarsus. The lesion was partially excised posteriorly under local anesthesia, and pathologists identified the mass as calcinosis cutis. The patient had no systemic or trauma history, and the serum levels of calcium and phosphorous were normal. Idiopathic calcinosis cutis should be included in the differential diagnosis for a protruding papillomatous mass of the tarsal plate, and surgical debulking could be a viable option for large protruding lesions, although more follow-up is necessary to monitor regrowth.
Adult
;
Calcinosis/*pathology/surgery
;
Eyelid Diseases/*pathology/surgery
;
Female
;
Humans
;
Skin Diseases/*pathology/surgery
2.Calcinosis cutis of bilateral knees: report of a case.
Hong-ji DING ; Chun-yan LIU ; Zhi-qiang LIU ; Jing LI ; Chuan-sen ZHANG
Chinese Journal of Pathology 2012;41(12):852-853
Calcinosis
;
pathology
;
surgery
;
Child
;
Diagnosis, Differential
;
Humans
;
Knee
;
Male
;
Skin Diseases
;
pathology
;
surgery
3.The application of free anterolateral thigh flap with a reporter skin paddle in the reconstruction of circumferential hypopharyngeal defects.
Weiwei LIU ; Email: LIUWWEI@MAIL.SYSU.EDU.CN. ; Hanwei PENG ; Xuekui LIU ; Zhuming GUO
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2015;50(6):477-481
OBJECTIVETo study the short-term results and technological improvement of free anterolateral thigh (ALT) flaps in the reconstruction of circumferential hypopharyngeal defects.
METHODSThe free ALT flap with a reporter skin paddle was used in 22 cases with circumferential hypopharyngeal defects. The short-term results of reconstructive surgeries and key points, advantages and complications of this technique were summarized.
RESULTSThe length of circumferential hypopharyngeal defects ranged from 7 to 9 cm. ALT flap with an area of (8-9) cm × (11-18) cm was harvested. A reporter skin island with the skin area of (2.0-3.0) cm × (2.5-4.0) cm was designed. 91% (20/22) of ALT flaps survived. Two cases with flap necrosis underwent second reconstruction with a pedicled pectoralis major flap. All the patients had patent anastomotic lumen. Good postoperative subjective swallowing evaluation was obtained in 59% (13/22) of patients; 41% (9/22) of patients had acceptable swallowing results. Three patients (14%) presented with postoperative pharyngocutaneous fistula. One case recovered spontaneously in short-term and other two cases received the second reconstructive surgery.
CONCLUSIONSThe application of free ALT flap with a reporter skin paddle in the reconstruction of circumferential hypopharyngeal defect is technologically easy and reliable, with satisfying swallowing function and limited trauma.
Free Tissue Flaps ; Humans ; Hypopharynx ; pathology ; surgery ; Pharyngeal Diseases ; surgery ; Reconstructive Surgical Procedures ; Skin Transplantation ; Thigh
4.Atypical Angioma Serpiginosum.
Ju Hsin CHEN ; Kuo Hsien WANG ; Chung Hong HU ; Jainn Shiun CHIU
Yonsei Medical Journal 2008;49(3):509-513
Angioma serpiginosum is an uncommon, acquired vascular nevoid disorder with capillary dilation and proliferation in the papillary dermis. The eruptions are asymptomatic and characterized by grouped, erythematous to violaceous, serpiginous and punctate macules. The condition usually appears in females during adolescence on unilateral lower extremities and the buttocks. We report a rare case with a late onset and atypical distribution of lesions in a 48-year-old female patient who had groups of punctate lesions on her left foot for four to five years. Histopathological examination showed hyperkeratosis and multiple dilated and proliferated capillaries in the papillary dermis. Inflammation and extravasation of red blood cells were not found. According to the clinical and pathological findings, we established a diagnosis of angioma serpiginosum. She was treated with a pulsed dye laser, and the angiomatous lesions subsequently improved.
Female
;
Foot Diseases/diagnosis/surgery
;
Humans
;
Lasers, Dye/therapeutic use
;
Middle Aged
;
Skin/blood supply/pathology/surgery
;
Skin Diseases, Vascular/*diagnosis/surgery
;
Telangiectasis/*diagnosis/surgery
;
Treatment Outcome
5.Pilomatricoma: a retrospective study of 399 cases.
Yongwei GUO ; Xia ZHAO ; Zhongwen ZHOU ; Zhongchun CHEN ; Songmin LIANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(21):1211-1213
OBJECTIVE:
To study the clinical and pathological features of pilomatricoma.
METHOD:
The authors retrospectively investigated the clinical and pathological materials of 399 patients with pilomatricoma.
RESULT:
Single lesion occurred in most patients (99%) and 56.39% of them were younger than 30 years. The male-female ratio was 1:1.33. The lesions which sizes average 1.22 cm were commonly emerged in the head, neck, and upper extremity.
CONCLUSION
Pilomatricoma is a slowly developed benign cutaneous tumour, but it can aggravate sometimes. It's manifestation is diversed and easily misdiagnosed. Early complete excision is recommended for hard or tenacious nodules on head, neck and upper extremity.
Adult
;
Extremities
;
Female
;
Hair Diseases
;
pathology
;
surgery
;
Head and Neck Neoplasms
;
pathology
;
surgery
;
Humans
;
Male
;
Middle Aged
;
Pilomatrixoma
;
pathology
;
surgery
;
Retrospective Studies
;
Skin Neoplasms
;
pathology
;
surgery
;
Tumor Burden
6.Extranodal Rosai-Dorfman disease.
Mei-fu GAN ; Tao ZHOU ; Xin-ru YU ; Chun-kai YU ; Hai-hong ZHENG ; Ju-fang CAI
Chinese Journal of Pathology 2005;34(3):137-139
OBJECTIVETo investigate the diagnosis and differential diagnosis of extranodal Rosai-Dorfman disease.
METHODSTwo cases of extranodal Rosai-Dorfman disease were studied using hematoxylin-eosin, and immunohistochemical staining, along with a literature review.
RESULTSThe lesions of RDD were characterized by the presence of large histiocytes with emperipolesis, accompanied by infiltration of lymphocytes, plasma cells and other inflammatory cells. The large histiocytes had an abundant cytoplasm, pale to eosinophilic in appearance, positive for S-100 protein staining, with a vesicular nucleus and a small basophilic nucleolus in each cell.
CONCLUSIONSExtranodal Rosai-Dorfman disease is known as an idiopathic proliferative disease of histiocytes with a distinct morphologic feature and is very rare. Differential diagnosis from other types of fibrohistiocytic proliferation lesions is recommended.
Antigens, CD ; metabolism ; Antigens, Differentiation, Myelomonocytic ; metabolism ; Brain ; pathology ; surgery ; Brain Diseases ; metabolism ; pathology ; surgery ; Dermatologic Surgical Procedures ; Diagnosis, Differential ; Histiocytosis, Sinus ; metabolism ; pathology ; surgery ; Humans ; Male ; Middle Aged ; S100 Proteins ; metabolism ; Skin ; pathology ; Skin Diseases ; metabolism ; pathology ; surgery
7.Unusual presentation of adult xanthogranuloma: a case report.
Lixian Chris TAN ; Kong Bing TAN ; Chen Wee Derrick AW
Singapore medical journal 2014;55(2):e25-7
Xanthogranulomas are the most common form of non-Langerhans cell histiocytosis. Both adult and childhood forms have been described. Adult cutaneous forms can present as solitary or multiple yellowish, orange-red or tan-hued papules. Herein, we present the case of a 28-year-old Chinese man with a skin-coloured nodule on his left nasal ala that persisted for several months. While initial impression was that of a fibrous papule of the nose, the results of an excision biopsy showed histological features corresponding to xanthogranuloma. This case demonstrates the condition’s myriad of dermatological presentations, and adds to the differential diagnoses of a cutaneous lesion found in the head and neck region.
Adult
;
Biopsy
;
Diagnosis, Differential
;
Granuloma
;
diagnosis
;
surgery
;
Histiocytosis
;
diagnosis
;
Humans
;
Male
;
Skin
;
pathology
;
Skin Diseases
;
diagnosis
;
surgery
;
Treatment Outcome
8.Manifestation and treatment of lipoid proteinosis in larynx.
Wen XU ; Lei WANG ; Li ZHANG ; Hong-gang LIU ; Fang ZAN ; Rong HU ; Wen-bin LIU ; De-min HAN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(4):301-304
OBJECTIVETo investigate the manifestation, characteristics and treatment of lipoid proteinosis (LP) in larynx.
METHODSSixteen cases of LP with hoarseness as the first sign were reported. The onset was in the newborn period in 10 cases. The upper eyelids were infiltrated in all cases, 13 of them reported an age of onset older than 6 - 8 years. The laryngeal behaviors and its treatment, multisystem manifestations, and characteristics of histopathology were evaluated.
RESULTSOne patient had moderate hoarseness, and the others had severe hoarseness. Videolaryngoscopy revealed thickening of the interarytenoid region and irregularities along the rims and the surface of the vocal folds due to yellowish papules. Oral tissues showed yellow-white infiltrates in 13 cases (81.3%). Whitish moniliform papules on the upper eyelids were found in all cases. Pock-like or acneiform scars were particularly evident on the face and the limbs in 14 cases (87.5%). Histologically, it was characterized by deposition of hyaline material in the submucosa and dermis of the eyelid or larynx with periodic acid-Schiff-positive and Congo red stain-negative. Eight patients underwent microlaryngosurgery for the excision of deposits in the vocal folds. The vocal function was significantly improved after surgery.
CONCLUSIONSOne of the most common features of lipoid proteinosis is hoarseness since infancy with laryngeal involvement. LP patients also display skin or mucosa infiltration of multiple systems. Microlaryngosurgical excision of the deposits in the vocal fold could improve the voice.
Adolescent ; Adult ; Child ; Female ; Humans ; Laryngeal Diseases ; diagnosis ; pathology ; surgery ; Larynx ; pathology ; surgery ; Lipoid Proteinosis of Urbach and Wiethe ; diagnosis ; pathology ; surgery ; Male ; Skin ; pathology ; Young Adult
9.The First Korean Case of Cutaneous Lung Tissue Heterotopia.
Ga Won JEON ; Seong Woo HAN ; Ji Mi JUNG ; Mi Seon KANG ; Jong Beom SIN
Journal of Korean Medical Science 2010;25(9):1387-1389
Cutaneous lung tissue heterotopia is a very rare disorder where mature lung tissues develop in the skin. This is only the second known report of cutaneous lung tissue heterotopia, with the first by Singer et al. in 1998. A newborn infant had a hemangioma-like, freely movable mass connected to the anterior aspect of the sternal manubrium. Pathologic findings showed mature lung tissues with bronchi, bronchioles, and alveoli through the dermis and subcutis, and it was diagnosed as cutaneous lung tissue heterotopia. Cutaneous lung tissue heterotopia is hypervascular, so grossly it looks like a hemangioma. It can be differentiated from pulmonary sequestration, teratoma, bronchogenic cyst, and branchial cleft cyst by histology and the location of the mass. We describe the clinical, radiologic, and pathologic findings of a cutaneous lung tissue heterotopia, the first reported in Korea.
Branchioma/pathology/surgery
;
Bronchogenic Cyst/pathology/surgery
;
Choristoma/*pathology/surgery
;
Humans
;
Infant, Newborn
;
*Lung
;
Magnetic Resonance Imaging
;
Male
;
Republic of Korea
;
Skin Diseases/*pathology/surgery
;
Skin Neoplasms/pathology
;
Tomography, X-Ray Computed