BACKGROUND: Pediatric infectious skin diseases are different from their counterparts in adults, since the sources of infection and disease progressions are distinct. To our knowledge, there have been no reports of epidemiologic studies of pediatric infectious skin diseases in Korea. OBJECTIVE: The purpose of this study was to evaluate the distribution of pediatric infectious skin diseases in the Ansan and Southwestern area of Gyeonggi-do, and to compare the results with previous reports about general pediatric dermatoses. METHODS: The authors retrospectively evaluated 4,366 cases of pediatric infectious skin diseases from July 2003 to June 2013 in the Department of Dermatology at Korea University Ansan Hospital. The monthly, seasonal, and annual incidences, as well as the ages and genders of the patients were evaluated. RESULTS: The study included 2004 (45.0%) girls and 2362 (55.0%) boys. The most frequent age of infection was 4 to 6 years old (range 0~15 years), and the peak incidences occurred in July, August, and January. The most common infectious dermatoses were viral (76.0%), bacterial (11.5%), fungal (8.3%), and parasitic (4.0%). The 10 most common pediatric infectious skin diseases were viral wart (45.8%), molluscum contagiosum (20.9%), impetigo (10.3%), tinea (7.1%), scabies (3.8%), herpes zoster (2.5%), varicella (1.6%), herpes simplex (1.5%), eczema herpeticum (1.1%), and cellulitis (0.9%). CONCLUSION: Compared to previously published reports, the distribution of pediatric infectious skin diseases has changed and was different from general pediatric dermatoses.
Adult ; Cellulitis ; Chickenpox ; Dermatology ; Disease Progression ; Epidemiologic Studies* ; Epidemiology ; Female ; Gyeonggi-do* ; Herpes Simplex ; Herpes Zoster ; Humans ; Impetigo ; Incidence ; Kaposi Varicelliform Eruption ; Korea ; Molluscum Contagiosum ; Retrospective Studies ; Scabies ; Seasons ; Skin Diseases ; Skin Diseases, Infectious* ; Tinea ; Warts

BACKGROUND: There have been many reports that have focused on the incidence of skin diseases in big cities or provinces. However, there have been no reports concerning the data of a new town such as Goyang City. OBJECTIVE AND METHODS: To study the prevalence of common dermatoses in the new town and to compare this with the previous reports, we reviewed the records of 15,064 outpatients who visited the Department of Dermatology at Myongji Hospital from 2004 to 2008, and we statistically analyzed the findings. RESULTS: The study results are summarized as follows: Of the 15,064 outpatients, the total number of male patients was 6,779 (45.0%), and the number of female patients was 8,285 (55.0%). The most frequent age group was the fourth decade followed by the first decade, third decade and fifth decade, and these 4 age groups comprised 63.7% of the total outpatients. The 15 most common dermatoses were found to be viral warts, dermatophytosis, atopic dermatitis, seborrheic dermatitis, pruritus, urticaria, irritant contact dermatitis, herpes zoster, alopecia, allergic contact dermatitis, acne, other eczema, melanocytic nevus, molluscum contagiosum and postinflammatory hyperpigmentation. For the occurrence of dermatoses as disease groups, 1) viral diseases, 2) diseases resulting from fungi and yeasts, 3) atopic dermatitis, eczema and noninfectious immunodeficiency disorders, 4) contact dermatitis and drug eruptions, 5) pruritus and neurocutaneous dermatosis, 6) seborrheic dermatitis, psoriasis, recalcitrant palmoplantar eruptions, pustular dermatitisand erythroderma, 7) erythema and urticaria, 8) Melanocytic nevi and neoplasm, 9) disturbances of pigmentation, and 10) diseases of skin appendages constituted 82.2% of the total. CONCLUSION: The distinct characteristic of skin diseases of the new town Goyang City showed a high incidence of viral warts and viral skin diseases, as compared to the previous reports.
Acne Vulgaris ; Alopecia ; Dermatitis, Allergic Contact ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Exfoliative ; Dermatitis, Seborrheic ; Dermatology ; Drug Eruptions ; Eczema ; Erythema ; Female ; Fungi ; Herpes Zoster ; Humans ; Hyperpigmentation ; Incidence ; Male ; Molluscum Contagiosum ; Nevus, Pigmented ; Outpatients ; Pigmentation ; Prevalence ; Pruritus ; Psoriasis ; Skin ; Skin Diseases ; Skin Diseases, Viral ; Statistics as Topic ; Tinea ; Urticaria ; Virus Diseases ; Warts ; Yeasts

A study evaluating the therapeutic effect of recombinant interferon-a ointment on several viral skin diseases was done. A total of 204 patients, 92 of herpes simplex, 90 of herpes zoster and 22 of varicella, were included in this study. Two different concentration of recombinant interferon-a ointment(l*10IU/g; group A, 1*10IU/g; group B) and placebo vehicle(control group) were applied topically on the early lesion of the disease. The evaluation of therapeutic effect was done by the measurement of time interval from the day of vesicle formation to the day of crust formation, The results were as follows; 1. Herpes sirnplex: Crust formation observed within 6 days in 70. 1% of group A. 63.9% of group B and 26.7%, of control group. The time of crust formation of group A and B was shorter than that of control group (p<0.01, P<0.05). 2. Herpes zoster: Crust formation observed within 10 days in 64. 3% of group A. 46.7% of group B and 33. 3% of control group. The time of crust formation of group A was shorter than that of control group (p<0.05). 3. Varicella: Crust formation observed within 6 days in 87. 5% of group A, 72.7% of group B and 66.7% of control group. Therefore we have been impressed that recombinant interferon-a ointment is an effective topical therapeutic agent and 1*10IU/g recombinant interferon-a clintment is more effective than 1*10IU/g recombioant interferon-a ointment for above viral skin diseases.
Chickenpox ; Herpes Simplex ; Herpes Zoster ; Humans ; Interferons* ; Skin Diseases, Viral*

Eczema herpeticum is a herpes simplex virus infection with disseminated skin involvement, which superimposes on a pre-existing dermatosis. Two siblings with simultaneous primary herpes simplex virus (HSV) infection on the normal skin of their backs, followed by their mother's herpes labialis. Eczema herpeticum was diagnosed on the basis of history, clinical feature, Tzanck test, histologic examination and a serologic test. Their skin lesions were healed by treatment with oral acyclovir and mupirocin ointment.
Acyclovir ; Eczema* ; Herpes Labialis ; Humans ; Kaposi Varicelliform Eruption* ; Mupirocin ; Serologic Tests ; Siblings* ; Simplexvirus ; Skin Diseases ; Skin*

No abstract available.
Eczema* ; Herpes Simplex* ; Kaposi Varicelliform Eruption* ; Simplexvirus*

A case of herpes simplex autoinoculated on the 1st interdigital web of right hand was reported, Herpes labialis characterized by confluent rice sized vesicular eruptions had developed on the midportion of upper lip. After 3 days, typical herpetic lesion occurred on the 1st interdigital web of right hand. We reviewed briefly the recent literatures.
Hand ; Herpes Labialis ; Herpes Simplex* ; Lip

BACKGROUND: Dermatological diseases can occur with atopic dermatitis. OBJECTIVE: The purpose of this study was to analyze diseases associated with atopic dermatitis in Koreans. METHODS: From November, 2007, to May, 2008, 948 patients with atopic dermatitis who visited the department of dermatology at 19 hospitals were evaluated for associated diseases. RESULTS: Of 948 patients, 53.8% (510) had symptoms associated with other dermatological diseases. In order of frequency, diseases associated with atopic dermatitis included acne, hand/foot eczema, seborrheic dermatitis, urticaria, warts, and recurrent herpes simplex. The number of associated diseases did not change significantly with the severity of atopic dermatitis. However, the incidence of hand/foot eczema and eczema herpeticum correlated significantly with the severity of atopic dermatitis. CONCLUSION: There is a distinct pattern of diseases associated with atopic dermatitis in Koreans.
Acne Vulgaris ; Dermatitis, Atopic ; Dermatitis, Seborrheic ; Dermatology ; Eczema ; Herpes Simplex ; Humans ; Incidence ; Kaposi Varicelliform Eruption ; Methylmethacrylates ; Polystyrenes ; Urticaria ; Warts

No abstract available.
Child, Preschool* ; Female ; Genitalia* ; Humans ; Molluscum Contagiosum* ; Warts*

BACKGROUND: Variable effectiveness of high dose cimetidine therapy for multiple warts, verruca plana and molluscum contagiosum has been reported. The immunomodulatory actions of cimetidine, an H2-receptor antagonist, and its use in the treatment of viral warts have been described previously but its effectiveness is still debated. OBJECTIVE: The purpose of this study is to evaluate the efficacy and safety of high dose cimetidine therapy for periungual warts. METHODS: Twenty seven patients with periungual warts were treated with high dose oral cimetidine (30~40 mg/kg/ day). RESULTS: Evaluable data was obtained in 20 (male 10, female 10) of the 27 patients enrolled in the study. 19 patients (95% of 20 patients) showed either complete resolution (50% of 20 patients) or partial resolution (45% of 20 patients) of their periungual warts without any side effect. CONCLUSION: Unlike aggressive therapies, oral high dose cimetidine administration is simple and cost effective and does not usually interfere with the patient's work activity or affect his or her social life. Though we can consider that high dose cimetidine therapy is one of the effective therapy for periungual warts, complete remission rate is not so high. Combined therapy with other topical therapy using liquid nitrogen, formic acid, silver nitrate or imiquimod, etc. would also be considered and evaluated for more effective treatment of periungual warts.
Cimetidine* ; Female ; Humans ; Molluscum Contagiosum ; Nitrogen ; Silver Nitrate ; Warts*

Epidermodysplasia vertuciformis (E.V.) is a generalized viral infection due to the wart virus, which is chacterized by wartlike papules often distributed over the entire body and generally starting in infancy, of which a high percetage develops into cancer. We present a case of E.V. in a 31 year old male with typical skin lesions resembling flat warts and tinea versicolor-like lesions that eventuated in malignancy, i.e., Bowens disease and squamous cell carcinoma on the forehead. The skin lesions appeared initially on the foerhead at the age of 6 and gradualIy generalized all over the whole bcdy thereafter. The light brown scaling papules on erythernatous hase and walnut sized ulcerative lesion on the forehead had been noticed for 4 to 6 years and identified as Bowens disease and squamous cell carcinoma.
Adult ; Bowen's Disease* ; Carcinoma, Squamous Cell ; Epidermodysplasia Verruciformis* ; Forehead ; Humans ; Juglans ; Male ; Skin ; Tinea ; Ulcer ; Warts