Esperson(R), a new topical steroid ointment containing 0. 05% 17-Desoxymethasone,. was used in several kinds of dermatoses. Framycetin which was isolated and uientified by the research organisation of Roussel Laboratories (SOFRAPEN) in 1950 from culture broths of a strain of Streptomyces species is a wide spectrum antibiotics on various bacterial infectious diseases. Total 50 patients including 10 cases of 2ndary infected Atopic dermatitis, 10 of infected Contact dermatitis, 6 of infected Seborrheic dermatitis, 7 of infected Neurodermatitis, 3 of infected Chronic dermatitis, 5 of lmpetigo, 2 of infected Nummular eczema, 2 of infected Infantile ecze;na, 1 of infected Intertrigo, 1 of Eczematoid Otitis extema, 1 of 2nd degree Bum, 1 of infected Pruritis ani, 1 of infeeted 1nsect bite. were treated with Frason(R) (0.05% 17-desoxymethasone & 0.5% Framycetin combination). Among these 50 patiants, we observed excellent effects in 7 patients (14%), good effect in 29 patients (58%), fair effect in 10 patients (20%), Totally 36 patients (72%) revealed excellent to good therapeutic effects on their skin conditione after unoccluded application of Frason(R). 3 times daily for about 14 days. There was no sid ffect in all subjects after application of Esperson-F.
Anti-Bacterial Agents ; Communicable Diseases ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Desoximetasone ; Eczema ; Framycetin ; Humans ; Intertrigo ; Neurodermatitis ; Otitis ; Pruritus ; Skin ; Skin Diseases* ; Streptomyces ; Sudden Infant Death

Demacre', a new topical steroid cream containing 0.025% beclomethasone dipropionate, was used in several kinds of dermatoses. Total 35 patients including ll cases of contact dermatitis, 5 of atopic dermatitis, 3 of hand eczema, 3 of seborrheic dermatitis, 2 of neurodermatitis, 2 of nummular eczema, 2 of autosensitization dermatitis, 1 of chronic eczema, 3 of psoriasis, 1 of insect bite, 1 of miliaria rubra, and 1 of intertrigo were treated by Demacre'. Among these patients, we observed excellent effects in 4 patients (11%), good effects in 22 patients (63%), and fair effects in 3 patients (9%). Namely, among these 35 patients, 26 patients (74%) revealed excellent to good therapeutic effects on their skin conditions with Demacre'. No untoward side effects were noted in all subjects treated with Demacre.
Beclomethasone ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Eczema ; Hand ; Humans ; Insect Bites and Stings ; Intertrigo ; Miliaria ; Neurodermatitis ; Psoriasis ; Skin ; Skin Diseases*

BACKGROUND: Occupational dermatoses are the most prevalent of all occupational diseases. Over the past few decades, the incidence of occupational dermatoses in Korea is increasing with rapid growth in industry. However, there have been only a few reports about occupational dermatoses in Korean dermatologic literature. OBJECTIVE: The purpose of this article is to study the prevalence of occupational dermatoses in a semiconductor industry and to compare these with previous reports. METHODS: A dermatologist attended regularly at the clinic in a semiconductor industry once a week from June 1995 to May 2000. 4, 985 workers diagnosed with skin disease were analyzed. RESULTS: The results can be summarized as follows: Annual incidences are 6.5%(1995.6-1996.5), 5.3%(1996.6-1997.5), 5.2%(1997.6-1998.5), 5.7%(1998.6-1999.5), 5.8%(1999.6-2000.5) and average incidence is 5.7%. In the distribution of dermatoses as disease groups, eczema(28.8%), fungal infection(19.2%), disease of skin appendage(17.6%), erythema, urticaria and drug eruption(9.4%), viral infection(4.9%), constituted 79.9% of the total. Ten most common dermatoses include contact dermatitis(13.1%), acne(12.5%), tinea pedis(11.2%), urticaria(7.5%), hand eczema(6.6%), seborrheic dermatitis(6.2%), onychomycosis(3.0%), alopecia(2.9%), tinea cruris(1.7%) and lichen simplex chronicus(1.6%). Diseases which shows high seasonal distribution in summer are contact dermatitis, tinea pedis, urticaria, tinea cruris. Contact dermatitis(1.7%), acne(1.6%), chemical burn(1.3%) and hand eczema(1.1%) were the most important occupational dermatoses in this survey. The occupational contact dermatitis and acne mainly came from the mask, hood and dust preventing clothes which the workers must wear for 8 hours a day at their work place. Hydrofluoric acid(1.0%) was the main cause of chemical burn. Hand eczema was primarily due to kitchen work, cleaning work and gloves. The other dermatoses related to occupation were trauma, seborrheic dermatitis, atopic dermatitis, xerosis cutis, urticaria, etc. CONCLUSIONS: Comparing these results about occupational dermatoses with previous report (1992.6-1995.5) in a semiconductor industry before, there was relatively low incidence of hydrofluoric acid burn and high incidence of contact dermatitis, acne and hand eczema.
Acne Vulgaris ; Burns ; Burns, Chemical ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Dust ; Eczema ; Erythema ; Hand ; Hydrofluoric Acid ; Incidence ; Korea ; Lichens ; Masks ; Occupational Diseases ; Occupations ; Prevalence ; Seasons ; Semiconductors* ; Skin ; Skin Diseases* ; Tinea ; Tinea Pedis ; Urticaria ; Workplace

BACKGROUND: There have been many reports that have focused on the incidence of skin diseases in big cities or provinces. However, there have been no reports concerning the data of a new town such as Goyang City. OBJECTIVE AND METHODS: To study the prevalence of common dermatoses in the new town and to compare this with the previous reports, we reviewed the records of 15,064 outpatients who visited the Department of Dermatology at Myongji Hospital from 2004 to 2008, and we statistically analyzed the findings. RESULTS: The study results are summarized as follows: Of the 15,064 outpatients, the total number of male patients was 6,779 (45.0%), and the number of female patients was 8,285 (55.0%). The most frequent age group was the fourth decade followed by the first decade, third decade and fifth decade, and these 4 age groups comprised 63.7% of the total outpatients. The 15 most common dermatoses were found to be viral warts, dermatophytosis, atopic dermatitis, seborrheic dermatitis, pruritus, urticaria, irritant contact dermatitis, herpes zoster, alopecia, allergic contact dermatitis, acne, other eczema, melanocytic nevus, molluscum contagiosum and postinflammatory hyperpigmentation. For the occurrence of dermatoses as disease groups, 1) viral diseases, 2) diseases resulting from fungi and yeasts, 3) atopic dermatitis, eczema and noninfectious immunodeficiency disorders, 4) contact dermatitis and drug eruptions, 5) pruritus and neurocutaneous dermatosis, 6) seborrheic dermatitis, psoriasis, recalcitrant palmoplantar eruptions, pustular dermatitisand erythroderma, 7) erythema and urticaria, 8) Melanocytic nevi and neoplasm, 9) disturbances of pigmentation, and 10) diseases of skin appendages constituted 82.2% of the total. CONCLUSION: The distinct characteristic of skin diseases of the new town Goyang City showed a high incidence of viral warts and viral skin diseases, as compared to the previous reports.
Acne Vulgaris ; Alopecia ; Dermatitis, Allergic Contact ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Exfoliative ; Dermatitis, Seborrheic ; Dermatology ; Drug Eruptions ; Eczema ; Erythema ; Female ; Fungi ; Herpes Zoster ; Humans ; Hyperpigmentation ; Incidence ; Male ; Molluscum Contagiosum ; Nevus, Pigmented ; Outpatients ; Pigmentation ; Prevalence ; Pruritus ; Psoriasis ; Skin ; Skin Diseases ; Skin Diseases, Viral ; Statistics as Topic ; Tinea ; Urticaria ; Virus Diseases ; Warts ; Yeasts

So far today the blood Picture of specific dermatoses such as leprosy, syphilis, skin tubercuIosis, pemphigus and eczema was studied a good many ways. Author has studied the blood picture especially red blood cells, hemoglobin, hematocrit, white blood cells and its differential counts in 217 cases of various skin diseases such as contact. dermatitis, urticaria, chronic eczema, atoPic dermatitis, seborrheic dermatitis, erythema multiforme, erythemanodosum, drug eruption, prurigo, lichen urticatus, exfoliative dermatitis and purpura. At the same time liver function tests were performed in 46 cases including 25 cases of contact dermatitis, 6 cases of chronic eczema, 5 cases of atopic dermatitis, 5 cases of urticaria and 5 cases of exfolistive dermatitis. Afterwards the correlations of those two groups were investigated. Among all mentioned above dermatose except purpura no changes of red blood cells, hemogiobin and hematocrit were observed according to the authors own control of normal values which were obtained in 62 normal healthy adults. Other findings are as follows; 1. In contact dermatitis leucocytes and eosinophils are increased while neutrophils slightIy decreased. 2. Moderate increase of lymphocytes in urticaria. 3. In chronic eczema leucocytes and lymphocytes slightly increased but neutrophils somewhat decreased. 4. In atopic dermatitis leucocytes and eosinophils increased and there was also moderate increase of lyrnphocytes. 5. In seborreheic dermatitis monocytes and basophils were increased but eosinophils were slightly increased. 6. In erythema multiforme monocytes were decreased and leacocytes increased slightly. 7. In erythema nodosum neitrophils increased and lymphocytes and monocytes were decreased. 8. In drug eruption monocytes were decreased. 9. ln Prurigo eosinophils were increased. 10.:ln lichen uiticatus neutrophils were decreased. 11. In exfoliative dermatitis there are marked increase of leucocytes and eosinophils and decrease of neutrophiIs, lymphocytes and basophils. 12. In purpura red b!ood cells, hemoglobin, hematocrit were decreased. The increase of white blood cells in contact dermatitis and exfoliative dermatitis almost paralleled with the extension of their lesions. Marked liver function disturbarces were found in a good many cases cf exfoliativedermatitis while slight degree of liver function disturbances were found in some cases of contact dermatitis and it was found that some cases of chronic eczema, urticaria and atopic dermatitis gave some influence to liver function. The fact of leucocytes increase in exfoliative dermatitis and contact dermatitis seems more or less go parallels with liver function disturbances.
Adult ; Basophils ; Dermatitis ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Exfoliative ; Dermatitis, Seborrheic ; Drug Eruptions ; Eczema ; Eosinophils ; Erythema Multiforme ; Erythema Nodosum ; Erythrocytes ; Hematocrit ; Humans ; Leprosy ; Leukocytes ; Lichens ; Liver ; Liver Function Tests ; Lymphocytes ; Monocytes ; Neutrophils ; Pemphigus ; Prurigo ; Purpura ; Reference Values ; Skin Diseases* ; Syphilis, Cutaneous ; Urticaria

In order to evaluate the effectiveness of clocortolone pivalate(Purantix) on corticosteroid responsive dermatoses, a symmetical paired. comparison technique was performed using 0. 1% clocortolone pivalate and 0. 025% triamcinolone acetonide creams. During the pericd of 7 months from September 1977 to March 1978, 37 patients with bilateral lesions of contact dermatitis, seborrheic dermatitis atopic dermatitis, lichen simplex chronicus and psoriasis were selected and treated with afore mentioned drugs, In the 15 psoriatic patients, clocrtolone pivalate was superior in 3, triamcinolone acetonide was superior in 2, 4oth drugs were equally effective in 10. In the evaluation of all 37 patients clocortolone pivalate was superior in 8, triamcinolone acetonide was sureior in 3, both drugs were equally effective in 26. The overall superiority of clocortolone pivalate to triamcinolone acetonide was non significant, There was no side effects with either drug. The simplicity of the vasoconstriction tcst has led to its general use in the study of the potency of new topical steroids. In the 6h occluded single-application vasocon-strictor test performed on 40 healthy students, there was no significant difference between clocortolone pivalate and triamcinolone acetonide, but they significantly d.ifferent from 1% hydrocortisone and the control; a simple ointment base(p<0.01).
Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Humans ; Hydrocortisone ; Neurodermatitis ; Psoriasis ; Skin Diseases* ; Skin* ; Steroids ; Triamcinolone Acetonide ; Vasoconstriction

BACKGROUND: The prevalence of other diseases associated with psoriasis has been investigated in recent years. OBJECTIVE: This study was performed to see diseases associated with psoriasis in Korea. METHODS: From september 1999 to May 2000, a total of 293 patients with psoriasis, who visited the department of dermatology in 6 hospitals were enrolled in a subject group for the study. We surveyed the incidence rates of associated diseases. RESULTS: In our study, diseases more concomitantly present in patients with psoriasis were dermatophyte infection, seborrheic dermatitis and benign tumor and nevus in skin diseases and obesity, diabetes mellitus, hypertension, gastritis and hepatitis in systemic diseases. Less concomitantly present in patients with psoriasis were erythroderma, acne, contact dermatitis, atopic dermatitis, bacterial infection, tonsillitis, and internal cancer. CONCLUSION: Our observations show a distinct pattern of diseases associated with psoriasis in Korea. Further investigation will be mandatory to elucidate concomitant diseases in psoriasis.
Acne Vulgaris ; Arthrodermataceae ; Bacterial Infections ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Exfoliative ; Dermatitis, Seborrheic ; Dermatology ; Diabetes Mellitus ; Gastritis ; Hepatitis ; Humans ; Hypertension ; Incidence ; Korea ; Nevus ; Obesity ; Palatine Tonsil ; Prevalence ; Psoriasis* ; Skin Diseases ; Tonsillitis

Frason' a new topical steroid ointment containing 0.05% 17-desoxymethason and 0.5 % framycetin, was in trial for several kinds of dermatoses. Total 40 patients including 8 cases of contact dermatitis, 6 seborrheic dermatitis, 4 atopic dermatitis, 4 pityriasis rosea, 4 acne vulgaris, 3 nummular eczema, 3 psoriasis vulgaris, 3 pustulosis palmaris et plantaris and 1 folliculitis were treated with Frason', and the results were as follows. 1) 29 patients revealed excellent or good therapeutic effects (72.5%) with unoccluded application of Frason ointment, 2 or 3 times daily, among the 40 patients. 2) In comparison with the 0.05% Frason' ointment and the 0.05% betamethasone- gentamycin cream, the 0.05% Frason' ointment was found to be slightly more effeetive in the aspect of anti-inflammatory and anti-bacterial action. 3) W/0 base of Frason' ointment had slightly irritating reaction compare to O/W base of betamethasone cream, There was no side effect except 1 patient who complained of buming sensation after initial application of Frason ointment.
Acne Vulgaris ; Betamethasone ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Eczema ; Folliculitis ; Framycetin ; Gentamicins ; Humans ; Pityriasis Rosea ; Psoriasis ; Sensation ; Skin Diseases

BACKGROUND: There has been no statistical study of dermatoses in the Ganganm area of Seoul which has been rapidly developing in the last 10 years. OBJECTIVE: We evaluated the recent distributions of dermatoses in the Gangam area of Seoul and compared them with the previous reports in Seoul and other provinces of Korea. METHODS: 47,015 new outpatients who visited the Yongdong Severance Hospital from 1983 to 1992 were analyzed statistically RESULTS: The study results are summarized as follows: 1. Among the 47,015 outpatients, the total number of number of male patients were 20,180(42.9%) and female patients 26,835(57.1%). 2. In age distribution, the most frequent age groups were the 3rd decade(21.3%), the lst decade(19.5%), and the 4th decade(19.2%) amounting to 60% of the total outpatients. 3. The most common 15 dermatoses were dermatophytosis, atopic dermatitis, urticaria, irritant contact dermatitis, acne vulgaris, allergic contact dermatitis, seborrheic dermatitis, other eczemas, warts, vitiligo, drug eruption, herpes zoster, psoriasis, bacterial infection, and syphilis. 4. Those dermatoses which showed an increasing tendency annually were seborrheic dermatitis, warts, vitiligo, and syphiiis. Dermatophytosis and bacterial infection showed a decreasing tendency. 5. Seasonal distribution showed that those diseases occurring most frequently during the summer were dermatophytosis, urticaria, allergic contact dermatitis, vitiligo, herpes zoster, and bacterial infection. The incidence of atopic dermatitis and psoriasis increased during the winter season. 6. In sexual distribution, acne, allergic contact dermatitis, and irritant contact dermatitis were more frequent in females, and the remainding common dermatoses did no show any difference. 7. In age distribution, atopic dermatitis and bacterial infection were most frequent in the lst decade. Urticaria, allergic contact dermatitis, acne, drung eruption, psoriasis, and syphilis were most frequent in the 3rd decade, with warts and vitiligo in the 2nd decade, and herpes zoster in the 6th decaded. 8. The distributions of dermotoses as disease groups were eczema(24.9%), urticaria-drug eruption (13.2%), dermatophytosis(10.7%), skin appendage disorder(10.1%), viral infection(10.1%), pigmentary disorders(4.5%), and papulosquamous diseases(4.0%) which constituted 78% of the total. 9. In patients dwelling in apartments, atopic dermatitis and molluscum contagiosumn showed a more frequent tendency in comparison to those living in house. 10. The most common 10 dermatoses among children were atopic dermatitis, urticaria, contact dermatitis, molluscum contagiosum, bacterial infection, dermatophytosis, vitiligo, other viral infections, and nevo-cellular nevi. On the other hand, the most common 10 dermatoses among the elderly were drmatophytosis, other eczemas, urticaria, herpes zoster, pruritus, contact dermatitis, drug eruption, lichen simplex chronicus, seborrheic dermatitis, and vitiligo. CONCLUSION: In contrast to earlier published report from Seoul, the infectous dermatoses, especially parasitic infestation, showed a decreasing tendency. The distribution pattern of the skin diseases did not differ fro other provinces of Korea in general.
Acne Vulgaris ; Age Distribution ; Aged ; Bacterial Infections ; Child ; Dermatitis, Allergic Contact ; Dermatitis, Atopic ; Dermatitis, Contact ; Dermatitis, Seborrheic ; Drug Eruptions ; Eczema ; Female ; Hand ; Herpes Zoster ; Humans ; Incidence ; Korea ; Male ; Molluscum Contagiosum ; Neurodermatitis ; Nevus ; Outpatients ; Pruritus ; Psoriasis ; Seasons ; Seoul* ; Skin ; Skin Diseases* ; Statistics as Topic* ; Syphilis ; Tinea ; Urticaria ; Vitiligo ; Warts

BACKGROUND: Telemedicine can be useful in dermatology on Ulleung island which is 217 km away from Pohang and without dermatologists. OBJECTIVE: The purpose of this study is to measure the effectiveness of telemedicine in treating skin diseases on Ulleung island. METHODS: 33 patients on Ulleung island were examined by a fullmotion real-time video by one dermatologist in a Dongsan hospital of Keimyung University once a week. From June 2011 to June 2012, there have been 53 treatments of telemedicine in 33 patients. RESULTS: 14 diseases were found in 33 patients. The most common disease group was infectious skin disease and eczema in 9 patients. In addition, there were other skin diseases such as acne vulgaris, allergic contact dermatitis, prurigo nodularis, lichen simplex chronicus, malignant melanoma, seborrheic dermatitis, polymorphous light eruption and so on. CONCLUSION: Dermatology favors telemedicine because we had investigated its value and possibilities by clinical experience of telemedicine between Ulleung island and Dongsan medical center in Daegu.
Acne Vulgaris ; Dermatitis, Allergic Contact ; Dermatitis, Seborrheic ; Dermatology ; Eczema ; Humans ; Light ; Melanoma ; Methylmethacrylates ; Neurodermatitis ; Polystyrenes ; Prurigo ; Skin ; Skin Diseases ; Skin Diseases, Infectious ; Telemedicine