OBJECTIVE: To understand the influence of shift work on common risk factors of cardiovascular disease in male workers in petrochemical enterprises.METHODS: A total of 981 male workers in a petrochemical enterprise were selected as study subjects by judgment sampling method.According to the current status of work shift,619 workers were in the shift group and 362 in the non-shift group.The differences in the related indicators of common risk factors of cardiovascular disease in these two groups were compared.RESULTS: The systolic blood pressure,diastolic blood pressure,uric acid,fasting blood glucose( FBG),and total cholesterol( TC) levels in workers of the shift group were higher than that in the non-shift group( P < 0.01).The diastolic blood pressure,serum FBG,TC,triglyceride levels,and obesity detection rate in the subgroup workers with a shift length ≥ 5.0 years were higher than that in the subgroup with shift length < 5.0 years( P < 0.05).The prevalence of hypertension,hyperglycemia,hyperlipidemia,and hyperuricemia in the study population were 9.3%,1.4%,19.9% and 33.4%,respectively.The prevalence of hyperuricemia increased with the increased working shift length( P < 0.01).The multivariate logistic regression analysis results showed that,the length of shift work was a risk factor for hyperuricemia( P < 0.01) after excluding the confounding factors such as age,body mass index,smoking and alcohol consumption.With the increase of the length of shift work,the risk of hyperuricemia increased.There was no correlation between shift working length and hypertension,hyperglycemia,and hyperlipidemia( P > 0.05).CONCLUSION: Shift work can increase the risk of hyperuricemia in male workers; shift work was not found to increase the risk of hypertension,hyperglycemia,and hyperlipidemia.

OBJECTIVE: To analyze the effects of hand-transmitted vibration operation on nailfold capillaroscopy( NFC) in fine sanding workers. METHODS: A total of 57 fine sanding workers of one golf ball production enterprise in Guangdong Province were selected as vibration exposure group and 30 workers without exposure to hand-transmitted vibration as control group by a judgement sampling method. NFC examination was carried out in workers of these two groups. RESULTS: The capillary haemorrhage detection rates,percentage of abnormal capillary loops and total capillary width in the vibration exposure group were higher than that in the control group [43. 9% vs 13. 3%,( 56. 6 ± 20. 9) % vs( 41. 2 ± 14. 5) %,( 44. 7 ± 4. 9) vs( 42. 4 ± 4. 9) μm,P < 0. 05]. The capillary density,capillary length and branch diameter in the vibration exposure group were lower than that in the control group [( 7. 7 ± 1. 0) vs( 8. 8 ± 1. 0) per mm,( 185. 1 ± 33. 9) vs( 205. 6 ± 23. 2) μm,( 18. 3 ± 1. 9) vs( 19. 6 ± 2. 6) μm,P < 0. 05]. No significant difference was found in the diameter of apical part and branch of capillaries between the two groups( P > 0. 05). In the vibration exposure group,the percentage of abnormal capillary loops in the left hand was lower than that in the right hand [( 53. 1 ± 20. 6) % vs( 61. 5 ±24. 2) %,P < 0. 01],the capillary length in the left hand of vibration exposure group was longer than that in the right hand [( 187. 2 ± 33. 5) vs( 179. 4 ± 35. 4) μm,P < 0. 05]. No significant difference was found in the capillary density,total capillary width,apical part diameter,output branch diameter and input branch diameter between two hands in the vibration exposure group( P > 0. 05). CONCLUSION: The hand-transmitted vibration can lower the nailfold capillary density,shorten and widen capillary loops, increase percentage of abnormal capillary loops and induce capillary haemorrhage. NFC could be used to assist early detection of microvascular damage induced by hand-transmitted vibration.