1.Development and application of multi-function joint device for oxygen supply by endotracheal tube
Zengwen WANG ; Xing WANG ; Yu WANG ; Sizhen WANG
Chinese Medical Equipment Journal 2004;0(07):-
Objective To solve the problem of additional airway resistance from oxygen supply tube and humidity liquid dropping tube in trachea pipe for patients with trachea dissection and intubatton along with the fixation of respiration detector.Methods The device was used in patients with trachea dissection and intubatton and the result is desirable.Conclusion This device solves the problem of additional airway resistance from oxygen supply tube and humidity liquid dropping tube in trachea pipe along with the fixation of respiration detector.It is an indispensable device for patients with trachea dissection and intubatton.
2.Diagnostic value of magnetic resonance imaging and high-frequency ultrasound for synovitis of the hip in children
Wei WANG ; Junrong CHEN ; Sizhen YU ; Ying LIU
Chinese Journal of Medical Physics 2024;41(6):734-738
Objective To explore the diagnostic value of magnetic resonance imaging(MRI)and high-frequency ultrasound for synovitis of the hip in children(SHC).Methods A total of 107 children suffering from hip pain were enrolled and underwent MRI and ultrasound examinations.The value of MRI and ultrasound for diagnosing SHC and identifying different types of SHC was analyzed.Results The result consistency between high-frequency ultrasound and clinical diagnosis was higher than that between MRI and clinical diagnosis(Kappa:0.717 vs 0.586).The AUC of the combined detection for diagnosing SHC was greater than that of MRI(0.844 vs 0.812,P<0.05).For the differential diagnosis of different types of SHC,the result consistency between high-frequency ultrasound and clinical diagnosis was higher than that between MRI and clinical diagnosis(Kappa:0.813 vs 0.630).The AUC of high-frequency ultrasound and the combined detection for differentiation between joint swelling type and joint effusion type of SHC was 0.903 and 0.912,higher than 0.815 of MRI(P<0.05).The detection rates of joint space abnormality,joint effusion,joint swelling and joint cartilage changes were 92.45%(49/53),73.91%(17/23),90.70%(39/43),and 77.78%(14/18)when using MRI,and those were 96.23%(51/53),91.30%(21/23),95.35%(41/43),and 88.89%(16/18)when using high-frequency ultrasound.There was no significant difference in the detection rates of pathological changes such as joint space abnormality between the two methods(P>0.05).Conclusion The combined detection of MRI and high-frequency ultrasound has high diagnostic value for SHC.
3.Study on mechanism of Dahuanglingxian Capsule for intervening gallstone formation by regulating ABCB11 and ABCC2
Qianli TANG ; Zhen LV ; Bing WANG ; Yu WANG ; Shu WANG ; Qingfeng SHU ; Bin GE ; Sizhen XIE
Chongqing Medicine 2018;47(1):4-6,10
Objective To explore the mechanism of Dahuanglinxian Capsule for intervening gallstone formation by regulating the expression levels of ABCB11 and ABCC2 mRNA and protein.Methods Forty male C57BL/6 mice were divided into the normal group(group N),model group (group M),ursodeoxycholic acid group (group U) and Dahuanglinxian Capsule treatment group (group D),10 cases in each group.The group N was fed with normal diet,while the group M,U and D were fed with lithogenic fodder for 8 weeks.Meanwhile the group U and D were given the medication intervention,once daily,for continuous 8 weeks of gavage.After successful modeling,mRNA and protein expression levels of ABCB11 and ABCC2 were detected by RT-PCR and immunohistochemistry.Results Compared with the other three groups,the expressions of ABCB11 and ABCC2 mRNA gene and protein in M group were significantly reduced(P<0.01);while,there was no statistical difference in the expressions of ABCB11 and ABCC2 mRNA and protein between the group D and N(P>0.05).Conclusion Dahuanglinxian Capsule can prevent the gallstone formation by regulating the expression of ABCB11 and ABCC2 mRNA and protein.
4. Overview of traditional Chinese medicine treatment and mechanism of functional diarrhea
Yu WANG ; Sizhen GU ; Danbo DOU
International Journal of Traditional Chinese Medicine 2019;41(9):1031-1034
Functional diarrhea is a common disease of the digestive tract system. Traditional Chinese medicine (TCM) mainly included herbal formulea, acupuncture and moxibustion to treat the functional diarrhea, according to the principles of strengthening spleen and moistening, nourishing spleen and kidney, and soothing liver. In recent years, many studies have been conducted on the effective mechanism of TCM treatment of functional diarrhea. However, further researches needed to be done on the micro-mechanism of TCM syndrome differentiation for functional diarrhea.