1.Application of clinical nursing pathway in clinical teaching for nursing practice students in neurosurgery department
Jiannan ZHANG ; Jiafeng WANG ; Siqin ZUO
Chinese Journal of Medical Education Research 2012;11(10):1043-1045
Objective To explore clinical nursing pathway(CNP) teaching method for nursing practice students.Methods Nursing practice students ( n =120 ) were randomly divided into two groups:experimental group and control group.CNP teaching method was applied in experimental group while traditional teaching method was used in control group.The test results of theory,operational skill,comprehensive quality,patient's satisfaction degree and nursing mistake between the two groups were compared.Results The results of theory,operational skill,comprehensive quality,patient's satisfaction degree in experimental group were obviously better than those in control group(P <0.05),the result of nursing mistake in experimental group was greatly decreased compared with that in control group(P < 0.05).Conclusion CNP teaching method is superior to traditional teaching method and it greatly improve the teaching quality.
2.Relation between astroglial activation state and ischemic tolerance in the gerbil hippocampus
Jingjun ZHANG ; Qing CHEN ; Siqin SUN
Chinese Journal of Pathophysiology 1986;0(02):-
AIM:To observe the relation between astroglial activation state and ischemic tolerance in the gerbil hippocampus. METHOD: Bilateral occlusion of common carotid arteries and immunofluorescent methods in the gerbil hippocampal tissue. Slices were used. The morphological changes of the neurons were observed by light microscopy.RESULTS:Pretreatment with 2 minute bilateral carotid artery occlusion produced protective effects of CA 1 neurons. Glial fibrillary acidic protein (GFAP) staining showed weak positive cells in control group. Most of GFAP positive cells showed weak and middle positive cells after recirculation 1d and 2d following ischemic 3.5 min and preconditioning of the brain with sublethal ischemia respectively.CONCLUSION:Astroglial played an important role in cerebral ischemia. It is possible that state of astroglial activation related to neuronal survival in ischemic tolerance.
3.~1H-MRS study of brain metabolic disorder in patients with cyanosed congenital heart disease
Siqin ZHANG ; Jingxia XIE ; Xiangke DU
Chinese Journal of Radiology 2000;0(11):-
Objective To study the metabolic alteration in the brain of patients with cyanosed congenital heart disease (CCHD) by using 1H magnetic resonance spectroscopy ( 1H MRS) and discover the pathophysiology of chronic hypoxic brain, which will help to diagnose and treat this disease completely. Methods Twenty five patients with CCHD and 25 controls were performed PRESS 1H MRS and MRI, The areas under the resonance of metabolites were measured, the ratios of the other metabolites to Cr were calculated and compared. Results In patients with CCHD, the mean value of NAA/ Cr was significantly lower than that in controls ( P 0.05). Conclusion 1H MRS can detect brain metabolic changes in patients with cyanosed congenital heart disease in vivo noninvasively and can detect the metabolism disorder of the energy and amino acid, so the pathophysiology of this disease can be understood.
4.Discussion on information system construction for postgraduate administration in affiliated clinical hospital
Shujing LIANG ; Hong CHEN ; Qinghuan ZHOU ; Lin QU ; Siqin ZHANG
Chinese Journal of Medical Education Research 2012;11(10):988-990
Postgraduate administration is faced with new challenge in the affiliated clinical hospital because of the increasing quantity of postgraduates.The paper analyzed the characteristics of postgraduate administration and the status quo of information system construction in the affiliated clinical hospital and proposed the ideas of constructing information system for postgraduate administration from three aspects including system-frame,system-function and system-management.The purpose of the study was to provide reference for improving quality of postgraduate administration.
5.Comparative analysis of double-blind review and open review of Ph.D candidates' thesis
Shujing LIANG ; Hong CHEN ; Qinghuan ZHOU ; Lin QU ; Siqin ZHANG
Chinese Journal of Medical Science Research Management 2012;25(4):262-264
Improvement of the review of dissertation for doctoral degree is important for the training of qualified doctors.Current practice includes double-blind review and open review.This paper compares and analyses the outcome of the two kinds of reviews and found that double-blind review is more objective that the other(the mean of open review score is 96.39±2.069,the mean of double-blind review score is 85.18±6.635.P=0.001,P<0.01).In the end some suggestions are proposed to improve the double-blind review system.
6.Problems in Ph.D education revealed by Double-blind review of Ph.D candidates' dissertation and counter-measures
Shujing LIANG ; Hong CHEN ; Qinghuan ZHOU ; Lin QU ; Siqin ZHANG
Chinese Journal of Medical Science Research Management 2012;(6):406-408
The paper analysed the double-blind review result of Ph.D candidates' dissertation at Peking University People's Hospital.Rigor deficiency and inadequate knowledge about the research subjects were identified as the main problems.In the end some suggestions were proposed from two aspects,namely,full-process management of Ph.D training and supervisor-team construction.
7.Expression and significance of TTF-1 and CgA in small cell lung carcinoma
Siqin HU ; Minghui ZHANG ; Qiong SHI ; Yan WANG
Journal of International Oncology 2015;(7):501-503
Objective To investigate the expression and clinical significance of thyroid transcription factor-1(TTF-1)and chromogranin A(CgA)in small cell lung cancer(SCLC). Methods The expressions of TTF-1 and CgA protein in 68 cases of SCLC tissues and 20 cases of normal lung tissues were examined by immunohistochemistry method,and their correlations with clinical features of SCLC were analyzed. Results The positive rates of TTF-1 and CgA protein in SCLC were 88. 2%(60 / 68)and 70. 6%(48 / 68),respec-tively,and they were higher than those in normal lung tissue[10. 0%(2 / 20)and 5. 0%(1 / 20);χ2 = 45. 442, P = 0. 000;χ2 = 26. 941,P = 0. 000]. The expression of TTF-1 protein was not related to the patients' age,sex and tumor size,while closely related to smoking index(χ2 = 4. 131,P = 0. 042),lymph node metastasis(χ2 =5. 488,P = 0. 019)and clinical stage(χ2 = 6. 011,P = 0. 014). The expression of CgA protein was not related to the patients' age,sex,tumor size and smoking index,while closely related to lymph node metastasis(χ2 =9. 895,P = 0. 002)and clinical stage(χ2 = 4. 145,P = 0. 042). Conclusion TTF-1 and CgA protein are highly expressed in SCLC,especially in the patients with lymph node metastasis and extensive disease.
8.Relationship between body fat distribution and pulse wave velocity in middle-aged and aged population
Xiafeng YAN ; Jianjun WANG ; Siqin REN ; Fenglei ZHANG
The Journal of Practical Medicine 2015;31(16):2645-2648
Objective To investigate the relationship between body fat distribution and pulse wave velocity (PWV) in middle-aged and aged population. Methods Two hundred patients received health examination were enrolled into the male group (103 cases) and the female group (97 cases). Visceral fat volume (VFV), subcutaneous fat volume (SFV) and ba-PWV were determined. Results Compared to patients in the female group, patients in the male group had significantly higher VFV values [(3.17 ± 0.84) kg vs (2.30 ± 0.94) kg], and lower SFV values [(15.56 ± 3.49) kg vs (17.69 ± 4.82) kg], In the male group, there existed a positive correlation between ba-PWV and age, VFV, fasting blood glucose,SBP and DBP. In the female group, a positive correlation was found between ba-PWV and age, SFV, TG, BUN, SBP and DBP, while a negative correlation was observed for HDL-C and Apo A1. Conclusion There was gender differences in body fat distribution in middle-aged and aged healthy population. In the male group , age, VFV, SBP, and DBP were the only independent and significant risk factors for ba-PWV. In the female group , age, SBP and Apo A1 were the independent risk factors for ba-PWV.
9.Imaging Study on Treatment of Femoral Head Bone Defect by the Recombination Vascular Endothelial Grouth Factor (VEGF) and Bone Morphogentic Protein (bBMP)
Hui ZHANG ; Yonggang WU ; Shufeng LIU ; Siqin LI ; Shengyong YI
Journal of Practical Radiology 1996;0(04):-
C groups and coincidence with pathological changes.After treatment fourth and twelfth weeks,ALP activity,calcium content was higher in group A than group B (?
10.The study on issues and strategy of TCM education for foreign students
Siqin HUANG ; Chenglin TANG ; Jie CHEN ; Dan ZHANG ; Jiuqing TAN ; Yuan ZHOU
Chinese Journal of Medical Education Research 2014;(7):709-711
Traditional Chinese Medicine as a rare heritage from our progenitor is becoming more and more important in the world. A lot of foreign students have come to China for learning TCM , and the number of foreign students has increased with time. A lot of issues occur during the teaching process for the foreign students. The problems including the source of students' quality, language, teaching material and clinic practice during the teaching process for the foreign students were ana-lyzed in the article, and the resolutions according to the problems were put forward to attract more and more foreign students to learn TCM and promote TCM in the world.