1.Challenges in the Management of a Child with Yolk Sac Tumour of the Nasal Cavity Presenting with Epistaxis and Progressive Respiratory Distress
Mohd Nor KHADIJAH ; Michelle Manuel ANURA ; Chew Man FONG ; Gan Chin SENG ; Tsiao Yi YAP ; Loong Siow PING ; Abdullah Wan ARIFFIN
Malaysian Journal of Medicine and Health Sciences 2018;14(1):57-60
Yolk Sac tumour (YST) of the nasal cavity is extremely rare with only less than five previously reported cases in the English literature. Due to its rarity, the diagnosis is not one that is considered at initial presentation until tissue biopsies are sent for histopathological examination. Serum α-fetoprotein levels aid in diagnosis and in monitoring progression of the tumour. Being a very uncommon tumour of germ cell origin presenting as localized disease in the nasal cavity, prognosis and survival rates are difficult to determine. We are reporting a rare yolk sac tumour case in an infant and the challenges encountered in its management.
2.CULTURAL ADAPTATION OF SNIFFIN’ STICKS TEST FOR A MALAYSIAN POPULATION
Siow Ping Loong ; Eugene Wong ; Revadi Govindaraju ; Ahmad Nordin Afandi ; Yves Brand ; Zulkiflee Abu Bakar ; Prepageran Narayanan
Journal of University of Malaya Medical Centre 2021;24(2):65-71
Introduction:
Sniffin’ Stick test is a quantitative olfactory test first introduced in the 1990s and has since been used in several countries after cultural-based modifications.
Objective:
To develop a culturally adapted Sniffin’ Stick test suitable for a Malaysian population.
Methods:
The study was done in 3 phases. The first phase involved a questionnaire rating the familiarity of 70 odors based on a Likert scale. Sixteen items were then selected for the second phase where subjects were tested on the identification of the 16 odors. Odors recognized by less than 75% of the subjects or their distractors were replaced. These steps were repeated until all 16 odors were recognized by more than 75% of the subjects. In the final phase, the mean Odor Identification (OI) scores utilizing the newly selected 16 odors were collected among healthy individuals.
Results:
A total of 417 subjects participated in the study. In the first-phase, 5 odors from the original Sniffin’ Stick Test which were unfamiliar were replaced for the phase 2 of the study. In the second-phase, modifications were performed 3 times requiring change of 41 distractors and an additional odor. Finally, using the modified Sniffin Stick test version-4, preliminary results of the mean odor identification scoring for the age groups 16-35,36-55 and more than 55 years of age were obtained which showed age-related variations.
Conclusion
Our study revealed cultural modifications to the original Sniffin’ Stick Test are required to validate its use in a Malaysian population.