The study was carried out on 320 patients with sinusititis at Hue Centre Hospital from Sept. 1998 to Mar. 2000; 76.5% of patients were 16-45 years old, 43.8% male and 56.2% female, 43% with 1 year long of the disease. The causes were infection 76.5%, allergy rhins-sinusitis 50.9%. Favorable factors: 49.1% local, 11.6% environmental, 2.5% systemic status. Clinical symptoms were headache 71.5%, cararrhal rhinitis 65.3% (posterior) and 48.4% (anterior), obstructive rhinitis 36.9%. Acite form sinusitis 12.8%, chronic 87.2%. In Blondeau Hirlz film: dim image of ethmoid sinus 96.4%, maxial sinus 60.6%, sphenoid sinus 24.2%, frontal sinus 5.2%. Complications occurred in 48.7%, the common were inflammation of the throat 27.2%, media otitis 21.9%. Within one year, the complication occurred in 35.8%, more 1 year 58%
Sinusitis ; Diseases ; complications ; epidemiology

Objective: To explore the correlation between eosinophils (Eos) and the incidence of chronic sinusitis with nasal polyps (CRSwNP) in Xinjiang region of China by comparing the proportion of inflammatory cells in the pathological tissues and peripheral blood. Methods: Retrospective analysis was performed on 582 patients with CRSwNP who underwent endoscopic nasal surgery in the First Affiliated Hospital of Xinjiang Medical University from January 2012 to March 2018, including 367 males and 215 females, aged (45.5±13.4) years (x¯±s). Patients were divided into groups according to demographic characteristics, recurrence and complication of allergic rhinitis (AR). Preoperative blood routine and postoperative pathological section data of nasal polyps were collected to compare the ratio of inflammatory cells in pathological tissue and the ratio of peripheral blood Eos in each group. The correlation between the proportion of inflammatory cells in the pathological tissue of nasal polyps and the recurrence of CRSwNP was analyzed, as well as the distribution of (eosCRSwNP) in Uygur and Han CRSwNP patients in Xinjiang region. Statistical analysis was performed by SPSS 19.0 software. Results: Compared with non-recurrent CRSwNP patients, the ratio of Eos in nasal polyp tissue and peripheral blood was increased significantly, (Z value was -3.142 and -2.344, respectively, both P<0.05). Compared with CRSwNP patients without AR, the ratio of Eos in nasal polyps and peripheral blood was also increased significantly in patients with AR (Z value was -6.664 and -4.520, respectively, both P<0.05). There was a positive correlation between tissue Eos and CRSwNP recurrence (r=0.130, P=0.002). The majority of CRSwNP patients were both eosCRSwNP in Uygur and Han ethnic groups. Conclusions: Eos is associated with the recurrence of CRSwNP in Xinjiang region, and eosCRSwNP is the dominant factor in both Uygur and Han patients.
China/epidemiology* ; Eosinophils ; Female ; Humans ; Male ; Nasal Polyps/epidemiology* ; Retrospective Studies ; Rhinitis/epidemiology* ; Sinusitis/epidemiology*

Humans ; Nasal Polyps/epidemiology* ; Cross-Sectional Studies ; Rhinosinusitis ; Asthma/epidemiology* ; Sinusitis/epidemiology* ; Chronic Disease

OBJECTIVETo investigate the risk factors of fungal rhinosinusitis.

METHODSThe preoperative clinical data of 57 patients with a diagnosis of fungal rhinosinusitis confirmed pathologically using Gomori methenamine silver staining were analyzed statistically against the data of 57 age- and gender-matched control patients with chronic rhinosinusitis.

RESULTSCompared with chronic rhinosinusitis, fungal rhinosinusitis was characterized by a significantly shorter mean disease course (37.31 months vs 130.84 months, t = 5.59, P = 0.000). The factors related to fungal rhinosinusitis included nasal mucus, purulent nasal discharge, unilateral/bilateral sinus lesion and calcified plaque in CT scan , with odds ratios of 0.17 (0.04-0.62), 0.35 (0.15-0.80), 41 (12.50-100.00) and 91 (24.01-344.95), respectively. Conditional logistic regression identified calcified plaque in CT scan as the high-risk factor of fungal rhinosinusitis.

CONCLUSIONThe presence of calcified plaque in CT scan indicates high risk of fungal rhinosinusitis and may serve as an important evidence for diagnosis of this disease.

Case-Control Studies ; China ; epidemiology ; Female ; Fungi ; Humans ; Male ; Mycoses ; epidemiology ; Rhinitis ; epidemiology ; microbiology ; Risk Factors ; Sinusitis ; epidemiology ; microbiology

OBJECTIVE: In order to make a basis for the treatment of nasal sinuses of children and the correlated disease, we investigate the incidence rate of nasal sinusitis of children and explore the correlation between nasal sinusitis of children and CT in Kunming. METHOD: Two thousand one hundred and fourteen healthy children and 1535 children with sinusitis were selected randomly. Form whom were undergone nasal sinus computer tomography for different medical reasons. The incidence rates of nasal sinusitis in different age-groups were calculated and statistically analyzed. RESULT: The incidence rate of sinusitis was highest in 4 to 8 years old. There was moderate to high consistency between clinical diagnosis and nasal CT results (P<0.01). CONCLUSION These results demonstrate that the key stage of children's sinusitis prevention would be school-age children, and nasal CT scanning is helpful to evaluate the clinical condition.
Adolescent ; Child ; Child, Preschool ; China ; epidemiology ; Female ; Humans ; Incidence ; Infant ; Male ; Sinusitis ; epidemiology

OBJECTIVE: To comparatively analyze the disease data of nasal sinus between helicopter and (strike) fighter pilots under flying qualification, and then to provide references for aeromedical support as a significant part of new logistics service union in army, METHOD: The CT data of nasal sinus in 138 pilots who accepted physical examination for change to new-type aircraft, were collected included 46 cases of helicopter pilots and 92 cases of (strike)fighter pilots). The incidence of chronic sinusitis and cyst of nasal sinus were computed respectively in helicopter pilots and (strike)fighter pilots. RESULT: (1) Fourteen cases suffered from chronic sinusitis (6 cases of maxillary sinusitis, 4 cases of ethmoiditis and 4 cases of maxillary sinusitis and ethmoiditis) in helicopter pilots whose incidence rate of chronic sinusitis was 30.4% (14/46). Of which, 3 cases of antracele were treated. Twelve cases suffered from chronic sinusitis (8 cases of maxillary sinusitis, 1 case of ethmoiditis, 3 cases of maxillary sinusitis and ethmoiditis) in (strike)fighter pilots whose incidence of chronic sinusitis was 13.0% (12/92). Of which, 1 case of antracele was treated. The incidence of chronic sinusitis was higher in helicopter pilots than (strike) fighters pilots (Chi2 = 6.07, P < 0.05). (2) Four cases suffered from unilateral mucosa cysts in maxillary sinus in helicopter pilots whose incidence of cyst of nasal sinus was 8.7% (4/46). Ten cases suffered from mucosa cysts in maxillary sinus (unilateral 8 cases and bilateral 2 cases) in (strike) fighters pilots whose incidence of cyst of nasal sinus was 10.87% (10/92). The difference of the incidence of cyst of nasal sinus was not statistically significant between the helicopter pilots and(strike)fighters pilots. The cysts of nasal sinus did not need treatment in 14 cases of this group data. CONCLUSION The incidence of symptomless chronic sinusitis and cyst of nasal sinus are high in pilots. It is related with repeatedly changes of atmosphere pressure during flying. But most chronic sinusitis and cyst of nasal sinus do not need treatment. The incidence of chronic sinusitis is higher in helicopter pilots than(strike)fighter pilots. It may be related with the environment of helicopter which have unclosed cockpit and load other aircrew.
Adult ; Aircraft ; Cysts ; epidemiology ; Humans ; Male ; Middle Aged ; Military Personnel ; Paranasal Sinus Diseases ; epidemiology ; Sinusitis ; classification ; epidemiology

In general, the etiologic factors of chronic paranasal sinusitis are systemic conditions such as nutrition, predisposition, allergy, and local factors such as nasal anatomic conditions. Among these factors, the development of unilateral sinusitis is a model case verifying the influence of local factors. In my study of 640 cases over a certain period of time, a comparison was made between 161 cases of unilateral sinusitis and 479 cases of bilateral sinusitis in order to verify the effects of local factors in the development of this disease. Patients with a history of previous sinus surgery or tumors were eliminated from the cases. 1. The male-female incidence rate, and the age distribution of the patients at the initial visit showed no prominent differences between unilateral and bilateral cases. 2. It was found that a larger number of cases of unilateral sinusitis had a duration of less than one year as compared to bilateral sinusitis which were longer than and year. Therefore it can be said that the duration of unilateral sinusitis is usually shorter than that of bilateral sinusitis. 3. In unilateral cases the patients with moderate to severe nasal septal deviation, one number of patients with septal deviation towards the diseased side was twice as high as that on the non-affected side. 4. The incidence rate of polyps occurring in the middle meatus was shown to be about twice as high in bilateral cases as in unilateral cases. 5. Comparing the size of the right and left maxillary sinuses, it was found that 103 cases (63.8%) of 161 patients with unilateral sinusitis showed a difference in size, and that only 171 cases (35.6%) of 479 patients with bilateral sinusitis showed a difference in size.
Adolescent ; Adult ; Age Factors ; Child ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Sinusitis/*epidemiology ; Time Factors

Allergic fungal sinusitis (AFS) is a benign, noninvasive variety of fungal sinusitis. AFS was first reported in 1983. The first case of AFS was associated with Aspergillus. However, it is now clear that most cases of AFS are caused by non-Aspergillus species. AFS is more frequently encountered at present due to changes in fungal taxonomy and improved culture techniques. There is a geographical difference in the incidence of AFS. It accounts for 5% to 10% of all cases of chronic rhinosinusitis requiring surgical intervention in the United States and has become a subject of increasing interest to otolaryngologists and related specialists. However, only 2 cases of AFS have been reported in Korea. It is extremely important to recognize AFS and to differentiate it from chronic bacterial sinusitis or other types of fungal sinusitis because the treatment and prognosis of these disorders are significantly different. The prognosis and optimum treatment of AFS are still unknown. This article reviews the current understanding of epidemiology, pathology, diagnosis and reatment of AFS.
Aspergillus ; Classification ; Culture Techniques ; Diagnosis ; Epidemiology ; Incidence ; Korea ; Pathology ; Prognosis ; Sinusitis ; Specialization ; United States

OBJECTIVETo explore the health-related quality of life (QOL) status of patients with chronic rhinosinusitis and nasal polyps.

METHODSOne hundred and twenty patients with chronic rhinosinusitis and nasal polyps and two hundred individuals passing health examination were enrolled by random and their QOL scores were assessed by using QOL instruments including existing SF-36 questionnaire (Chinese version ) and SNOT-20 questionnaire translated into Chinese, of which clinimetric and psychometric properties were tested.

RESULTSThe feasibility, reliability, validity, and responsibility of Chinese version of SNOT-20 questionnaire all passed the test. By the assessment of SF-36 questionnaire, it revealed that scores of six domains such as physical functioning, role physical, bodily pain, mental health, vitality, and general health from patients with chronic rhinosinusitis and nasal polyps were lower than that of control group except social functioning and role emotional (P < 0.05). It showed by Chinese version of SNOT-20 questionnaire that patients exceeded healthy individuals in the scores of twenty items of three domains including physical problems, functional limitations, and emotional consequences, of which the most five important items affecting health status were respectively need to blow nose, thick nasal discharge, lack of a good night's sleep, dizziness, and post-nasal discharge (P < 0.05).

CONCLUSIONSQOL instruments such as Chinese version of SF-36 and SNOT-20 questionnaires can effectively differentiate the QOL status between patients with chronic rhinosinusitis and nasal polyps and healthy individuals. The negative impact of chronic rhinosinusitis and nasal polyps on patients' QOL includes physical functioning, role physical, bodily pain, mental health, vitality, general health, and emotional consequences. The problems of nasal discharge, sleep, and dizziness should be sufficiently emphasized in clinical treatment.

Adolescent ; Adult ; Aged ; Asian Continental Ancestry Group ; China ; epidemiology ; Chronic Disease ; Female ; Humans ; Male ; Middle Aged ; Nasal Polyps ; epidemiology ; ethnology ; Quality of Life ; Sinusitis ; epidemiology ; ethnology ; Surveys and Questionnaires

OBJECTIVEThe purpose of this article is to establish an endoscopic score system for quantitative evaluation of the inflammation of mucous membrane in patients with chronic rhinosinusitis (CRS) , and to investigate the correlation of this system with a variety of clinical factors.

METHODSA set of score system was constructed based on anatomic configuration, status of mucous membrane and nasal secretion to evaluate quantificationally the severity of inflammation of CRS. The clinical correlation of this system was studied prospectively in 60 CRS patients, with a variety of clinical factors which included age, duration of disease, previous recurrence and the years from recent recurrence, atopy, serum total immunoglobulin E (TIgE), serum eosinophil cationic protein (ECP), the count of blood eosinophil, the count of tissue inflammatory cell, the extension of CRS indicated by CT, smoking, concomitant chronic inflammation in lower respiratory tract. All above factors were analyzed statistically with the endoscopic score by Pearson correlation and multi-factor linear regression analysis.

RESULTSIn pearson analysis, the correlative factors with the evaluated score included age (x1, r = - 0.310, P = 0.016), the extension of disease (x2, r = 0. 810, P < 0.0005), recurrence (x3, r = 0.408, P = 0.001), eosinophil of nasal tissue (x4, r = 0.279, P = 0. 031), duration of disease (x5, r = 0.536, P < 0.0005), concurrent nasal polyps (r = 0.549, P < 0.0005), plasm cell (r = 0. 317, P = 0.014) and years from the recent recurrence (r = 0.385, P = 0.002). In multi-factor linear regression, the five independent predictive factors were recurrence, age, extension of disease, tissue eosinophils, years of disease. The regressive equation is y = 10.148 - 0.152 (x1) + 2.250 (x2) + 3.348 (x3) + 1.233 (x4) + 0.270 (x5).

CONCLUSIONSAppropriate score system by nasal endoscopy is feasible to evaluate quantificationally the degree of inflammation of CRS; being appropriately modified, it is even able to reveal the underlying histological behavior finely.

Adolescent ; Adult ; Aged ; Chronic Disease ; Endoscopy ; Eosinophils ; Female ; Humans ; Immunoglobulin E ; blood ; Male ; Middle Aged ; Nasal Polyps ; diagnosis ; epidemiology ; Rhinitis ; diagnosis ; epidemiology ; Sinusitis ; diagnosis ; epidemiology ; Young Adult