1.Management of an Anophthalmic Patient by the Fabrication of Custom Made Ocular Prosthesis
Meenakshi Singh ; Meghanand Nayak ; Jitender Solanki ; Sarika Gupta ; Anjali Singh
Malaysian Journal of Medical Sciences 2015;22(3):75-79
The loss or disfigurement of a body parts specially that pertaining to the face has a deep psychological and social impact on the patient. After enucleation, evisceration or exteneration of the eye, the aim of an ocular prosthesis should be to restore the natural appearance, install confidence and a sense social acceptability in the patient. Custom made prosthesis has several advantages over the stock eye prosthesis. This article illustrates rehabilitation of the enucleated right eye of a patient with a custom made ocular prosthesis.
2.The current approach to the diagnosis of vascular anomalies of the head and neck: A pictorial essay.
Sinny GOEL ; Swati GUPTA ; Aarti SINGH ; Anjali PRAKASH ; Sujoy GHOSH ; Poonam NARANG ; Sunita GUPTA
Imaging Science in Dentistry 2015;45(2):123-131
Throughout the years, various classifications have evolved for the diagnosis of vascular anomalies. However, it remains difficult to classify a number of such lesions. Because all hemangiomas were previously considered to involute, if a lesion with imaging and clinical characteristics of hemangioma does not involute, then there is no subclass in which to classify such a lesion, as reported in one of our cases. The recent classification proposed by the International Society for the Study of Vascular Anomalies (ISSVA, 2014) has solved this problem by including non-involuting and partially involuting hemangioma in the classification. We present here five cases of vascular anomalies and discuss their diagnosis in accordance with the ISSVA (2014) classification. A non-involuting lesion should not always be diagnosed as a vascular malformation. A non-involuting lesion can be either a hemangioma or a vascular malformation depending upon its clinicopathologic and imaging characteristics.
Classification
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Diagnosis*
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Head*
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Hemangioma
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Neck*
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Vascular Malformations
3.Rapid metabolic fingerprinting with the aid of chemometric models to identify authenticity of natural medicines:Turmeric,Ocimum,and Withania somnifera study
Khan SAMREEN ; Rai Kumar ABHISHEK ; Singh ANJALI ; Singh SAUDAN ; Dubey Kumar BASANT ; Lal Kishori RAJ ; Negi Singh ARVIND ; Birse NICHOLAS ; Trivedi Kumar PRABODH ; T.Elliott CHRISTOPHER ; Ch RATNASEKHAR
Journal of Pharmaceutical Analysis 2023;13(9):1041-1057
Herbal medicines are popular natural medicines that have been used for decades.The use of alternative medicines continues to expand rapidly across the world.The World Health Organization suggests that quality assessment of natural medicines is essential for any therapeutic or health care applications,as their therapeutic potential varies between different geographic origins,plant species,and varieties.Classification of herbal medicines based on a limited number of secondary metabolites is not an ideal approach.Their quality should be considered based on a complete metabolic profile,as their pharmacological activity is not due to a few specific secondary metabolites but rather a larger group of bioactive compounds.A holistic and integrative approach using rapid and nondestructive analytical strategies for the screening of herbal med-icines is required for robust characterization.In this study,a rapid and effective quality assessment system for geographical traceability,species,and variety-specific authenticity of the widely used natural medicines turmeric,Ocimum,and Withania somnifera was investigated using Fourier transform near-infrared(FT-NIR)spectroscopy-based metabolic fingerprinting.Four different geographical origins of turmeric,five different Ocimum species,and three different varieties of roots and leaves of Withania somnifera were studied with the aid of machine learning approaches.Extremely good discrimination(R2>0.98,Q2>0.97,and accuracy=1.0)with sensitivity and specificity of 100%was achieved using this metabolic fingerprinting strategy.Our study demonstrated that FT-NIR-based rapid metabolic fingerprinting can be used as a robust analytical method to authenticate several important medicinal herbs.