1.Spinal Ganglion Cyst of Lumbar Posterior Longitudinal Ligament.
Sung Woo ROH ; Seung Chul RHIM ; Ho Kyu LEE ; Sin Kwang KANG
Journal of Korean Neurosurgical Society 2000;29(4):543-549
No abstract available.
Ganglia, Spinal*
;
Longitudinal Ligaments*
2.A Case of Cutaneous Polyarteritis Nodosa.
Hyun Chul CHAE ; Kyung Hee CHOI ; Mi Soo AHN ; Ji Sub OH ; Sin Kwang KANG
Journal of the Korean Pediatric Society 1995;38(10):1422-1428
No abstract available.
Polyarteritis Nodosa*
3.Clinical Study fo Pulmonary Thromboembolism.
Sang Myeon BAK ; Sang Hwa LEE ; Sin Hyung LEE ; Cheol SIN ; Jae Youn CHO ; Jae Jeong SHIM ; Kwang Ho IN ; Kyung Ho KANG ; Se Hwa YOO
Tuberculosis and Respiratory Diseases 2001;50(1):106-116
BACKGROUND: Pulmonary thromboembolism is relatively frequent and potentially fatal. However, it is commonly misdiagnosed. The incidence of pulmonary thromboembolism is not decreasing despite advances in diagnosis and effective prophylatic measures. Its potential for significant sequela necessitates a prompt diagnosis and treatment. Unfortunately, there are many difficulties and problems regarding accurate diagnosis. There is a low prevalence of deep vein thrombosis and pulmonary thromboembolism in Korea and only few reports on this subject are available. METHOD: The clinical features of 36 patients, who were diagnosed with pulmonary thromboembolism at the Korea University medical center, were reviewed. RESULTS: 1) There was no significant difference in prevalence between men an women, and the mean age was 50.9 years in men 59.2 years in women. 2) The frequent causes of pulmonary thromboembolism were malignancies (22.2%), surgery (22.2%), and heart disease(8.2%). Specific causes were not identified in 33.3%. 3) The most common symptom was dyspnea(72.2%), and the most common sign was tachypnea(61.1%). 4) The EKG findings were normal in 28.6%, and S1Q3T3 pulmonale pattern in 25.7%, ST or QRS changes in others. 5) The chest X-ray findings indicated pulmonary infiltation in 37.5%, cardiomegaly in 15.6%, pleural effusion in 12.5%, and normal in 27.8%. The perfusion lung scan showed a high probability in 66.7%, and intermediate or low probability in 33.3%. 6) The pulmonary arterial pressure(PAP) in the high probability groups was 57.9mmHg with a higher mortality rate(35%). CONCLUSION: Pulmonary thromboembolism is not uncommon in Korea and its clinical features do not differ greatly from those reported in the literature. When pulmonary thromboemblism of unknown causes are diagnosed, a search for an occult malignancy is recommended. Rapid diagnosis and treatment are achieved when thromboemblism is suspected.
Academic Medical Centers
;
Cardiomegaly
;
Diagnosis
;
Electrocardiography
;
Female
;
Heart
;
Humans
;
Incidence
;
Korea
;
Lung
;
Male
;
Mortality
;
Perfusion
;
Pleural Effusion
;
Prevalence
;
Pulmonary Embolism*
;
Thorax
;
Tomography, Spiral Computed
;
Venous Thrombosis
4.Open heart surgery 600 cases for 5 years.
Kwang Hyun CHO ; Yoon Ho WHANG ; Yang Haeng LEE ; Jong Weon PARK ; Sin Hyun JUNG ; Kang Ju CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(4):404-420
No abstract available.
Heart*
;
Thoracic Surgery*
5.A Case of Adult Neuronal Ceroid-Lipofuscinosis, Proven by Brain Biopsy.
Soon Keum LEE ; Joong Koo KANG ; Sang Ahm LEE ; Jung Kyo LEE ; Sin Kwang KANG
Journal of the Korean Neurological Association 2001;19(1):45-48
A 20-year-old woman was admitted because of intractable seizures, myoclonus, gait ataxia, and severe intellectual deterioration with age of onset at 16 years. She had no family history of neurological disease. A thorough laboratory investigation was unremarkable. Brain MRI showed generalized cerebral and cerebellar atrophy. Interictal EEG showed intermittent generalized polyspike and waves, maximum on the bilateral parieto-occipital areas, and MNSEP showed giant cortical SEP. Brain biopsy revealed intraneuronal accumulation of granular osmiophilic deposits (GROD), which is characteristic of electromicroscopic findings of neuronal ceroid lipofuscinosis (NCL). We report biopsy-proven adult NCL, which is one of the rare neurodegenerative diseases. (J Korean Neurol Assoc 19(1):45~48, 2001
Adult*
;
Age of Onset
;
Atrophy
;
Biopsy*
;
Brain*
;
Electroencephalography
;
Female
;
Gait Ataxia
;
Humans
;
Magnetic Resonance Imaging
;
Myoclonus
;
Neurodegenerative Diseases
;
Neuronal Ceroid-Lipofuscinoses*
;
Neurons*
;
Seizures
;
Young Adult
6.Effects of Immunostimulatory CpG-Oligodeoxynucleotides of Bronchial Asthma in Rat.
Sin Hyung LEE ; Je Hyeong KIM ; Hye cheol JEONG ; Kyung Kyu KIM ; Ki Hwan JUNG ; Byung Gyu KIM ; Seung Heon LEE ; Sang Myun PARK ; Cheol SIN ; Jae Youn CHO ; Jae Jeong SHIM ; Kwang Ho IN ; Se Hwa YOO ; Kyung Ho KANG
Tuberculosis and Respiratory Diseases 2001;50(1):12-28
BACKGROUND AND OBJECT: Immunostimulatory CpG-oligodeoxynucleotides (ISS CpG-ODN) up-regulate the TH1-type immune response and down-regulate the TH2-type response. This study was performed to investigate the immune response changes resulting from ISS CpG-ODN on bronchial hyperrestponsiveness, eosinophilic inflammation and mucus hypersecretion in rat asthma. MATERIALS AND METHODS: 10 normal controls(NC) and 26 asthmatic rats, which were generated by ovallbumin(OVA) sensitization and challenge, were studied. The asthmatic rats were randomized into 11 asthma controls(AC) and 15 in the asthma-CpG treatment group(CpG). The CpG group was administered ISS CpG-ODN intramuscularly and the AC group was administered a placebo(0.9% NaCl)on day 15 and 20. After CpG-ODN or placebo administration, we measured the IFN-(TH1-type cytokine) and IL-4(TH2-type cytokine) levels in the bronchoalveolar lavage fluid(BALF), the specific airway resistance(sRaw), eosinophilic fraction in BALF, eosinophilic infiltration, goblet cell dysplasia and MUC5AC gene expression in the lung tissue. RESULTS: In the BALF of the CpG group, the IFN-γ concentration was significantly high and the IL-4 concentration was significantly low when compared with the AC group. Both the sRaw and eosinophilic fraction, and infiltration into the BALF and lung tissue significantly lower in the CpG group when compared with the AC group. However, little difference in goblet cell dysplasia and MUC5Ac gene expression was observed between the CpG group and the Ac group. CONCLUSION: ISS CpG-ODN decreases bronchial hyperresponsiveness and eosinophilic inflammation in the rat asthma model through the up-regulation of the TH1-type immune response with the down-regulation of the TH2-type response. However, the effect of these immune response changes on mucus hypersecretion was is not remarkable in this study.
Animals
;
Asthma*
;
Bronchoalveolar Lavage
;
Down-Regulation
;
Eosinophils
;
Gene Expression
;
Goblet Cells
;
Inflammation
;
Interleukin-4
;
Lung
;
Mucus
;
Rats*
;
Up-Regulation
7.A case of tumorous type of endobronchial tuberculosis simulating bronchial adenoma.
Sin Gu KANG ; Ae Ra HONG ; Chong Ju KIM ; Kwang Seon SONG ; Suk Joong YONG ; Kye Chul SHIN
Tuberculosis and Respiratory Diseases 1996;43(5):818-823
The tumorous type of endobronchial tuberculosis was reported to be 5 to 10% in the bronchoscopic examination. It was protruding mass that tuberculous mediastinal lymph node ruptured into the bronchial lumen. Generally histologic examination has been performed for purpose of differentiation, because the tumorous type of endobronchial tuberculosis simulate lung cancer in bronchoscopic finding. A case considering operation similar to bronchial adenoma in the bronchoscopic finding was confirmed to endobronchial tuberculosis by positive AFB and disapperance of mass after antituberculosis medication. Case history was presented and reviewed.
Adenoma*
;
Bronchoscopy
;
Lung Neoplasms
;
Lymph Nodes
;
Tuberculosis*
8.A case of Unilateral Absence of Pulmonary Artery.
Kwang Sin JOH ; Dong Soo KIM ; Chul Joo RYU ; Shin Heh KANG ; Sung Kyu LEE ; Ki Young LEE ; Dong Shik CHIN
Journal of the Korean Pediatric Society 1986;29(5):95-99
No abstract available.
Pulmonary Artery*
9.Immunogenicity of a Recombinant Hepatitis B Virus Vaccine Compared with a Plasma-derived Hepatitis B Vaccine and of Vaccination Schedules in Neonates.
Ae Sil KANG ; Jong Sin KIM ; Jae Won HUH ; Chang Youn LEE ; Hyun Gi JUNG ; Jae Sun PARK ; Kwang Soo HWANG
Journal of the Korean Pediatric Society 1995;38(11):1525-1534
No abstract available.
Appointments and Schedules*
;
Hepatitis B Vaccines*
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
;
Humans
;
Infant, Newborn*
;
Vaccination*
10.A Case of Mixed Long Carcinoma Composed of Three Cell Type.
Sin Goo KANG ; Kwang Sun SONG ; Jung Ju KIM ; Ae Ra HONG ; Do Hoon KIM ; Hee Sun KIM ; Suk Joong YOUNG ; Kye Chul SHIN ; Soon Hee JUNG
Korean Journal of Medicine 1997;53(5):699-704
Carcinoma of lung is classified by histologic cell type, this is based on predominant major cell population by tissue specimen. But in fact a range of 13% to 63% of lung cancer has been appeared to be heterogeneous cell type at the light microscopic level. After treatment of the mixed lung cancer and/or with time there are reports that cell type is changed. Because it is possible that the tumor were pleomorphic and that the antitumor therapy eliminated the more sensitive cell population and permitted the subsequent emergence of the more resistant cell population. The authors reported here, a case of 32 year old female patient with mixed lung cancer composed of three cell type, and this is the first case in Korea.
Adult
;
Female
;
Humans
;
Korea
;
Lung
;
Lung Neoplasms
;
Population Characteristics