In the process of achieving the “Healthy China 2030” goal， the importance of health knowledge popularization behavior is increasingly prominent. Medical communication has emerged to meet the growing demand for medical popularization and improve the shortage of professional medical staff in medical knowledge popularization. At present， literature is relatively scarce on the development process of medical communication in the academic community. By analyzing the development process of this discipline， this paper divided the development process of the knowledge system of medical communication into three stages， including the “initial stage”， the “practical exploration stage”， and the “rapid development stage”. After summarizing the different characteristics exhibited in the three stages， it can be concluded that the number of colleges and universities offering medical communication courses is gradually increasing， and social organizations such as the Society of Medical Communication have been established one after another， expanding the influence of the discipline. The development of medical communication not only helps to enhance the popularization and communication abilities of medical students， but also accelerates the development of China’s health industry through its extensive influence at the practical level.