Objective To investigate the value of video-assisted thoracoscopic surgery(VATS)in the treatment of coagulated hemothorax.Methods A prospective randomized controlled study.Between July 2005 and July 2007,62 patients with coagulated hemothorax were enrolled in this study.The patients were randomly divided into VATS and traditional thoracotomy groups(31 in each).The pathophysiological parameters of the two grups were compared.Results No significant difference in the sex,age,property and location of the wound,and rate of complicated injuries was noticed between the two groups.The mean operation time,duration of postoperative drainage,and postoperative hospital stay of the VATS group were significantly shorter than those in the traditional group [(52.1?24.4)min vs(120.2?47.2)min,t=-7.136,P=0.000;(1.7?0.7)d vs(4.8?1.8)d,t=-8.937,P=0.000;and(12.6?2.4)d vs(18.0?8.9)d,t=-3.262,P=0.002;respectively];and the mean intraoperative blood loss and the volume of thoracic drainage of the VATS group were significantly lower than those in the traditional group [(137.1?14.6)ml vs(203.2?53.4)ml,t=-6.648,P=0.000;and(181.3?37.9)ml vs(253.9?64.0)ml,t=-5.435,P=0.000,respectively].No significant difference in the rate of complications existed between the two groups(0 vs 1 case,?2=0.000,P=0.000).Conclusion Video-assisted thoracoscopy is feasible and safe for coagulated hemothorax and is worth being widely used.

Objective: To investigate the prevalence and influencing factors of dyslipidemia among adult residents in Hefei City, so as to provide the evidence for formulating the dyslipidemia control strategy. Methods: A total of 10 812 permanent residents at ages of 18 years were randomly sampled from 5 counties (districts) in Hefei City using a multi-stage stratified cluster random sampling method. Participants' demographic features, dietary behaviors and development of chronic diseases were collected using questionnaire surveys, and the height, body weight, waist circumference and blood lipids were measured. The prevalence of dyslipidemia was analyzed, and the factors affecting the development of dyslipidemia were identified using a multivariable logistic regression model. Results: Totally 10 812 valid questionnaires were recovered, with an effective recovery rate of 92.02%. The participants had a male to female ratio of 0.85∶1, a mean age of (51.89±12.56) years. The prevalence of dyslipidemia was 25.20%, and hypertriglyceridemia and low high-density lipoprotein cholesterol (HDL-C) were predominant types of dyslipidemia, with prevalence of 12.70% and 10.20%, respectively. Multivariable logistic regression analysis showed that urban areas (OR=1.340, 95%CI: 1.219-1.474), age of 40 years and older (40 to 59 years, OR=1.181, 95%CI: 1.047-1.333; 60 to 88 years, OR=1.321, 95%CI: 1.154-1.513), alcohol consumption (OR=1.205, 95%CI: 1.093-1.329), insufficient physical activity (OR=1.217, 95%CI: 1.111-1.332), static behavior duration of 3 h/d and longer (OR=1.126, 95%CI: 1.027-1.234), overweight (OR=1.162, 95%CI: 1.045-1.291), obesity (OR=1.310, 95%CI: 1.097-1.564), central pre-obesity (OR=1.236, 95%CI: 1.102-1.387), central obesity (OR=1.414, 95%CI: 1.247-1.603), hypertension (OR=1.279, 95%CI: 1.107-1.477), diabetes (OR=2.192, 95%CI: 1.820-2.640), medical insurance (OR=0.594, 95%CI: 0.395-0.893) and self-rated “very good/good” oral health (OR=0.731, 95%CI: 0.576-0.927) were factors affecting the development of dyslipidemia. Conclusion The risk of dyslipidemia is high among adult residents living in urban areas, middle-aged and elderly residents, residents with alcohol consumption, insufficient physical activity, overweight, obesity, central pre-obesity, central obesity, hypertension and diabetes.

ABSTRACT:To understand the status of contamination and antimicrobial resistance of Staphylococcus aureus (S .aureus) isolated from raw cow milk ,600 samples were collected from five different provinces in China .After isolation and identification of S .aureus from these samples ,157 S .aureus isolates were obtained .Furthermore ,their resistant phenotype and resistant gene were analyzed by MIC detection ,as well as nine drug‐resistance genes determination and analysis .The result revealed that most of the S .aureus isolates contained multiple antibiotic resistant genes ,and all of the isolates were resistant to penicillin . Of 98 .73% isolates were resistant to amoxicillin .Conversely ,all of the isolates were sensitive to enrofloxacin and vancomycin . Moreover ,there were 29 MRSA positive strains among which 22 strains carrying femA gene .In conclusion ,much more atten‐tion should be paid to the drug‐resistance capabilities of field S .aureus isolates in raw cow milk ,and further monitoring of drug resistant S .aureus strains in milk should also be strengthened so as to ensure milk safety .

Objective To study the arterial stiffness in non-diabetic pre-dialysis chronic kidney disease (CKD) patients and to explore the associated factors. Methods Automatic pulse wave velocity (PWV) measuring system was used to examine carotid-femoral pulse wave velocity (CFPWV) as the parameters reflecting central elastic large arterial elasticity. Vascular calcification was quantitatively evaluated by plain radiographic film of abdomen, pelvis and hands. Blood pressure, biochemical parameters and intact parathyroid hormone (iPTH) were routinely detected. Stepwise multiple linear regression analysis was used to assess the associated factors of arterial stiffness. Results Ninety-six non-diabetic pre-dialysis CKD patients and 30 healthy people were enrolled in this trial. CFPWV in stage 3, 4 and 5 CKD patients was significantly higher than that in healthy controls [(11.63±2.39) m/s, (11.70±2.80) m/s, (12.88±2.49) m/s vs (9.70±1.66)m/s , all P<0.05]. Stepwise multiple regression analysis demonstrated that age, mean arterial pressure, vascular calcification and iPTH were independent impact factors of CFPWV. Conclusions Arterial stiffness of large artery increases in non-diabetic pre-dialysis CKD patients. Age, mean arterial pressure, vascular calcification and iPTH are independent impact factors of CFPWV.

OBJECTIVE: To analyze the epidemiological characteristics and related risk factors of allergic rhinitis in primary and middle school students in Changsha so that to provide the scientific basis for the disease control and intervention. METHOD: From June 2011 to April 2012, we randomly chose primary and middle school students aged from 10 to 17 years old in Changsha as our research objects. Through stratified sampling and cluster sampling, we carried out epidemiological investigation using questionnaire investigation, physical examination and skin prick test. After statistical analysis of the data,we explored the related risk factors. RESULT: (1) 7,023 copies of questionnaire were sent out and 6,407 copies of valid questionnaire were received in the stratified sampling survey. The prevalence of complaining about having got allergic rhinitis is 44.6% while the real rates is 20.5%; (2) 814 research objects were investigated in cluster sampling survey. The result of the incidence of allergic rhinitis is 26.3%, and the prevalence of allergic rhinitis is 17.2%. Analysis of Visual Analog Scale Questionnaire showed significant influence of allergic rhinitis on students character, memory, sleep quality, etc. CONCLUSION The prevalence of allergic rhinitis in primary and middle school students aged at 10-17 years old in Changsha is 17%-20%. The occurrence and development of allergic rhinitis is related to environment, genetic background and living habits. Allergic rhinitis influenced the students' character, memory and sleep quality significantly.
Adolescent ; Child ; China ; epidemiology ; Factor Analysis, Statistical ; Female ; Humans ; Incidence ; Male ; Prevalence ; Rhinitis, Allergic ; epidemiology ; Risk Factors ; Students ; Surveys and Questionnaires

Hematopoietic stem cell transplantation in children has the characteristics of less stem cell for transplantation and higher acceptability of donors. The article reviews the classification, clinical application, general planning and clinical advantages of hematopoietic stem cell transplantation in children, to provide a new treatment for children's immune system diseases and genetic and metabolic diseases.

Objective To explore the clinical effect of color Doppler ultrasound guided small incision in repairing penile fracture.Methods Sixteen cases of penile fracture single cavernosum rupture adopted the preoperative positioning by color Doppler ultrasound,hematoma removal and albuginea repair.The clinical effect was evaluated after operation.Results The albuginea rupture was smoothly found in 15 cases,1 case was converted to coronary sulcus annular degloving incision.The operation time was 20-60 min with a mean of 35 min;the postoperative hospital stay was 3.0-6.0 d with a mean of 4.8 d;the catheter removal was on postoperative 3-5 d,urination was unobstructed.Follow up lasted for 6-12 months,1 case appeared transient erectile dysfunction,the harden was touched during erection in 1 case,and other cases had no obvious complication occurrence.Conclusion The color Doppler ultrasound can locate the rupture of corpora cavernosa penis and albuginea.Selecting color Doppler ultrasound guided small incision in repairing penile fracture has small trauma and less complications,and can get satisfactory effect.

Objective: To evaluate the safety and efficacy of oblique lateral interbody fusion (OLIF) in the surgical treatment of lumbar degenerative diseases. Methods: All literatures of OLIF performed in lumbar degenerative diseases were searched in recognized databases including Pubmed, OVID, Embase, Cochrane Library, Science Direct, springer, CNKI, Wanfang and VIP databases. Methodological Indexfor Non-randomized Studies (MINORS) was used to evaluate the quality of the literatures. The meta-analysis was performed using Review Manager 5.3 and Stata 15.0 statistical software. Results: A total of 35 literatures were included, including 22 English literatures and 13 Chinese literatures. There were 3 630 patients with 45.2% of males, aged from 14 to 89 years old (mean, 62.6 years). The average of length of stay (LOS), operation time (OT) and blood loss (BL) of OLIF procedure were 6.7 days, 117 minutes, and 128 ml, respectively. The VAS scores of low back pain of postoperative and final follow-up decreased by 4.33 and 4.70, respectively. The VAS scores of leg pain decreased by 4.57 points and 5.31, respectively. Compared with preoperative, the postoperative JOA score increased by 7.58 and the postoperative ODI were also improved by 33.89%. All the postoperative imaging data were significantly different from those before surgery. The surgical level intervertebral heightincreased 4.14 mm, and the intervertebral foramen height and intervertebral foramen area increased by 3.54 mm, 53.96 mm², while the dura sac cross-sectional area increased by 36.61 mm², and the overall lumbar lordosis increased by 13.78° with the local segmental lordosis increased by 4.62°. The overall incidence of complications of OLIF was 32%, with a 95% confidence interval of 25%-38%. Conclusion OLIF is a minimally invasive procedure for the treatment of lumbar degenerative diseases. OLIF has a simply procedure and short learning curve, with short LOS and operation time, less blood loss. OLIF can effectively open the narrow intervertebral space and increase the spinal canal and nerve root canal, significantly improve the symptoms, while the complication rate is low, so OLIF is worthy of widespread clinical application.

Objective To observe the clinical effect of temozolomide combined with radiotherapy in the treatment of malignant gliomas. Methods A total of 64 patients with pathologically confirmed glioblastoma received radiotherapy combined with chemotherapy in our hospital from January 2008 to January 2014, radiotherapy synchronized with TMZ chemotherapy were used in 39 patients (synchronized group) and radiotherapy sequential with TMZ chemotherapy in 25 patients (sequential group).1 year and 3 year survival rates, response rate and drug safety were compared between the two groups. Results The patients were followed up for 6 months to 3 years, the synchronous group of patients 1 years and 3 years survival rates (74.4%, 38.5%) were higher than the sequential group(64.0%, 28.0%) (P<0.05), objective re-sponse rate of two groups were 64.1%and 44.0%, the difference was statistically significant(P<0.05), gastrointestinal re-action rates of two groups were 23.1% and 20.0%, the difference was not statistically significant (P>0.05). Adverse re-actions were statistically significant (P<0.05). Conclusion The effect of radiotherapy synchronized combined with TMZ chemotherapy is better than radiotherapy sequential with TMZ chemotherapy for glioblastoma, it is still the first choice for the treatment of glioblastoma although the clinical manifestations of toxicity increased than the sequential group.

Objective To investigate the effect of neuronavigation assisted microscopic transsphenoidal resection of non-invasived pituitary tumor. Methods Retrospective analysis of clinical data of 72 cases of transsphenoidal operation for non-invasived pituitary tumor from January 2012 to January 2014. Results All patients were successfully completed the surgery, total resection in 65 cases, subtotal resection in 4 cases, partial resection in 3 cases, 7 cases in subtotal resection were treated with gamma knife radiotherapy after operation, hyperprolactin were given bromocriptine treatment after surgery. Patients were followed up for 6 months to 3 years, the remission rate was 89.2% in the postoperative headache, visual disorder remission rate 68.6%, endocrine disorders and the remission rate was 57.6%. 5 cases of post-operative cerebrospinal fluid rhinorrhea underwent repair, 8 cases had diabetes insipidus, 1 case of partial resection progressed to suprasellar and parasellar after 1.5 years, underwent craniotomy operation again. Conclusion For non-in-vasived pituitary tumor, microscopic transsphenoidal sugery is safe, convenient, and has no significant difference com-pared with the effect of endoscopic endonasal transsphenoidal approach.