1.A comparison of the demographic, clinical, knowledge, and cultural profiles of breast cancer patients with delayed consultation seen at Vicente Sotto Memorial Medical Center (VSMMC) Breast Center.
Mangaoil James Edward R ; Siguan Stephen SIXTO
Philippine Journal of Surgical Specialties 2008;63(4):139-142
OBJECTIVES: The study aimed to describe the demographic profile and determine the cause of delayed consultation among breast cancer patients seen at the Vicente Sotto Memorial Medical Center (VSMMC) Breast Center. The differences between these delayed consultations compared with those who consulted promptly, in terms of clinical, demographic, knowledge and cultural factors were determined.
METHODS: A survey of all female patients with breast cancer seen at the Breast Center of the VSMMC from September 2007 to February 2008, analyzing demographic, clinical, knowledge and cultural factors was conducted. Statistical analysis was done using chi square to determine factors significantly associated with delayed consultation.
RESULTS: Sixty-six (65.4%) out of 101 subjects had consulted late. Most of the delays were due to financial constraints. Delayed consultation was significantly associated with patient's low educational attainment up to elementary level only, and the patient's negative perceptions regarding the cause and possible cure of their cancer. During this time period, most breast cancer patients consulted late for their condition, primarily because of financial reasons.
CONCLUSIONS: In summary, this study showed that financial factors, and inadequate education were major causes of delayed consultations. Inappropriate cultural beliefs may have also contributed to this delay. Modification of current advocacies in the community served by VSMMC is needed to address this problem. Financial support through the community, in whatever form, may be significant in decreasing the incidence of delayed consultation for breast cancer.
Human ; Female ; Breast ; Breast Neoplasms ; Financial Support
2.Adult-onset cystic hygroma in the axilla in a 44-year old female: A case report.
Stephen Sixto Siguan ; Mary Nicole A. Velez
Philippine Journal of Surgical Specialties 2019;74(2):44-49
This is a case of a 44- year old female presenting with an 18cm x 17cm
soft, movable, non-tender mass at the right axilla extending to the
lateral aspect of the right breast. Computerized tomographic scan of the
chest revealed a lobulated, multi-septated hypodense mass. The patient
underwent excision of the right axillary mass and final histopathology
revealed cystic lymphangioma. Adult-onset cystic hygroma of the axilla
is a rare case, with less than 10 studies documented in PubMed. Total
surgical excision remains to be its primary treatment.
Lymphangioma
;
Axilla
3.A review of the accuracy of sentinel lymph node biopsy by comparing frozen section with final paraffin block H&E staining, and correlation with the final axillary lymph node dissection results.
Siguan Stephen SIGUAN ; Bordeos Lloyd NARIO ; Baking-Fernandez Saleshe Tracy Anne
Philippine Journal of Surgical Specialties 2016;71(2):41-45
OBJECTIVES: 1) To determine the accuracy rate of sentinel lymph node? biopsy? (SLNB)? by? comparing? frozen? section? (FS)? with permanent formalin processed specimen by hematoxylin and eosin (H&E) staining; 2) To correlate with axillary lymph node dissection (ALND) histopathology results for those with positive SLNB.
METHODS: This? was? a? retrospective? study? on? all? breast? cancer patients? who? underwent? SLNB? using? methylene? blue? dye.? The number of SLN harvested, number of lymph nodes confirmed on frozen section, frozen section result, number of SLN confirmed on paraffin block H&E, result of H&E. If frozen section of SLN was positive for metastasis, further data on the axillary lymph nodes harvested and its final H&E result were noted. The accuracy rate was determined.? Whenever a discordance of FS and H&E findings occurred, the interpreting pathologists were interviewed for the cause.
RESULTS: A total of 34 SLNB procedures were performed. There were 24 SLNBs that turned out negative on frozen section while 10 were positive for metastasis and underwent further ALND. Three of the 24 negative SLNBs turned out to be positive (false negative rate of 12.5%). Out of the 10 positive SLNBs, 1 turned out to be negative (false positive rate of 10%). Only 6 of the 10 patients with (+) SLNB had? more? positive? nodes? harvested? upon? further? ALND.The accuracy rate of SLNB on frozen section was 88%, with sensitivity and? specificity? of? 90%? and? 87.5%? respectively.? There? were? 5 pathologists involved in the interpretations of the SLNB, and in 76% the? pathologist? interpreting? the? FS? was? different? from? the? one interpreting? the? permanent? specimen? H&E.? The? reasons? for discordance between frozen section and final H&E reading were inter-reader variability and tissue sampling limitation during frozen section.
CONCLUSION:?The accuracy of frozen section in SLNB procedure is 88%.
Human ; Sentinel Lymph Node Biopsy ; Hematoxylin ; Methylene Blue ; Formaldehyde ; Lymph Nodes ; Axilla ; Lymph Node Excision ; Breast Neoplasms
4.Clinical and demographic profile of male breast patients seen at Vicente Sotto Memorial Medical Center (VSMMC).
Pepito Alice A ; Siguan Stephen SIXTO ; Ligo Eliezer L
Philippine Journal of Surgical Specialties 2006;61(1):1-5
INTRODUCTION: Palpable breast tissue is so prevalent in studies of men and boys that some authors suggest differentiating it from clinically important gynecomastia. Understanding male breast problems present a great challenge to many physicians especially when there is no specific guidelines developed for men.
OBJECTIVES: This study aims to determine the demographic and clinical profile of male patients with breast problems consulting at Vicente Sotto Memorial Medical Center.
METHODOLOGY: This study is a review of 77 male patients seen at the breast center of Vicente Sotto Memorial Medical Center from April 1, 2001 to March 31, 2004. The clinical profile included the age, geographic origin, chief complaint, family history of breast cancer, clinical breast examination findings, attributes of the clinically palpable breast mass like number, size, consistency, laterality, location, associated breast pain and pain score, clinical diagnosis and final histopathologic report.
RESULTS: Within this time period, there were 2,669 consultations seen at the breast clinic. A total of 77 male patients, comprising 2.9 percent were seen at the clinic. The mean age of occurrence was 36.2 years old. The frequency distribution of breast problem is highest between the ages of 20 to 29 years old at 40.3 percent. In all of the 69 patients (89.61 percent) with clinically palpable mass, 66 patients (95.65 percent) only had a solitary mass while 3 patients (4.35 percent) had two masses. Forty-three (59.7 percent) of the masses were less than 2 centimeters in diameter. Only 1 (1.4 percent) of the 72 masses was fixed to the chest wall which turned out to be a soft tissue sarcoma while the rest (98.6 percent) were freely movable. Based on the final histopathologic results, gynecomastia was the most common diagnosis among patients subjected to fine needle aspiration biopsy and excisional biopsy.
CONCLUSION: Male breast problems are common in the third decade of life and among patients living the urban area like Metro Cebu. Male patients sought consultation due to problems of unilateral firm breast mass less than 2 centimeters in diameter located in the nipple-areola complex. The most common clinical diagnosis is that of gynecomastia which is supported by the final histopathologic result of the same condition.
Human ; Male ; Mastodynia ; Nipples ; Gynecomastia ; Thoracic Wall ; Breast Diseases ; Breast Neoplasms ; Sarcoma
5.Clinical analysis of 1,393 females with mastalgia.
Laurito Arnold A. ; Siguan Stephen SIXTO ; Ligo Eliezer L.
Philippine Journal of Surgical Specialties 2006;61(2):62-65
To determine the clinical profile of benign and malignant mastalgia in terms of age distribution, geographic location, laterality, pain severity and pattern.
METHOD: This is a 3-year (April 1,2001 until March 31, 2004) retrospective chart review of female patients presenting with mastalgia in a hospital-based government breast center at Vicente Sotto Memorial Medical Center, Cebu City. Malignant mastalgia was diagnosed based on histopathologic findings. Pain severity assessment was based on a numeric scale of 0 to 10. Exclusion criteria include patients without mastalgia as chief complaint, no histopathologic confirmation of malignancy and males. All statistical computations were done using Chi square test with a = 0.05.
RESULTS: A total of 1237 patients (89 percent) had benign mastalgia with an average age of 29.72 +/- 10.96 years and 156 (11 percent) had malignant mastalgia with an average of 48.92 +/- 11.96 years. Patients less than 60 years of age had a statistically significant probability that their mastalgia is due to benign pathology (p < 0.001 at a 0.05). However, for 60 years of age. there is a significant probability that the cause of mastalgia is malignant (p < 0.001). Right-sided mastalgia showed a significant probability for a benign cause (p value of 0.0132). Further, non-cyclical pain pattern significantly connotes malignant mastalgia with p < 0.001. No significant differences were found for geographic location and pain severity.
CONCLUSION: Age above 60 years, right-sidedness and non-cyclical pain pattern are the only significant factors for differentiating whether the mastalgia is due to a benign or malignant etiology.
Human ; Female ; Mastodynia ; Age Distribution ; Philippines ; Breast ; Probability ; Neoplasms
6.Patterns of mammogram utilization and clinical profile of patients who underwent mammography at Cebu (Velez) General Hospital.
Siguan Stephen SIXTO ; Auguis-Atilano ADORA ; Medalle Edwin RAY
Philippine Journal of Surgical Specialties 2003;58(1):22-26
BACKGROUND: Educating physicians on the proper utilization of mammography is vital to effective implementation of the breast cancer control program.
OBJECTIVE: The general objective of this study was to determine the patterns of mammogram utilization and clinical profile of patients who underwent mammography at Cebu (Velez) General Hospital from January 1997 to February 2001.
METHODS: Checklists embodying important breast health information, clinical data (age, sex, address, menstrual and obstetrical history, personal and family history of breast cancer, presenting breast signs and symptoms), referring physicians, and mammography reports over the last four years were reviewed.
RESULTS: There were 468 mammograms done of which 279 (60 percent) were for diagnostics purposes and 189 (40 percent) for screening. The highest number of women who underwent screening mammography belonged to the 50-59 year age group. Gynecologists were the most frequent referring physicians for mammographic examination at 186 (40 percent) followed by 134 (29 percent) referrals from the general surgeons. There was an increasing trend of mammogram utilization noted over the past four years. Palpable mass in 172 (53 percent) patients was followed by mastodynia in 104 (33 percent) patients accounting for the most common indications for diagnostic mammography. Three hundred seventy-three (80 percent) mammogram results were negative and only 23 (5 percent) showed suspicious abnormalities warranting biopsy. Three hundred twenty-five (69.4 percent) of the mammograms showed extremely dense breasts which lowered sensitivity. There was a trend towards decreasing Grade IV radiographic density of the breast as the patients were older. Proper mammogram utilization at Cebu Velez General Hospital has increased over the last 4 years.
Human ; Female ; Aged ; Middle Aged ; Adult ; Adolescent ; Child ; Mastodynia ; Checklist ; Mammography ; Breast ; Breast Neoplasms
7.Correlation of tumor characteristics and adjuvant treatment in recurrent breast cancer at the Vicente Sotto Memorial Medical Center
De Leon Joseph Alfred B. ; Siguan Stephen Sixto
Philippine Journal of Surgical Specialties 2011;66(1):9-12
Background:
This study was conducted to determine the factors which may affect the incidence and recurrence of breast cancer in patients treated at the Vicente Sotto Memorial Medical Center (VSMMC).
Methods:
Utilizing hospital records, a case-control study was done on all breast cancer patients, treated at the VSMMC from January 200 to December 2007, comparing those who developed recurrence and those who did not.
Results and Conclusions:
Of the total of 404 patients treated at VSMMC during this period, only 370 patients (91.6%) with complete records were retrieved and included in the study. Overall recurrence rate was 17.8%. Age, parity, menopausal status nor family history of breast cancer, tumor characteristics, nor adjuvant therapy compliance, were the same for the two groups. More patients without recurrence underwent hormonal therapy (P=0.113). Those patients with recurrent breast cancer more often had positive lymph nodes (P=0.007).
Key words: recurrent breast cancer
NOT IDENTIFIED
8.An eight-year experience of implementing a pro-active approach to early detection of breast cancer in a community.
Merilles Pierre Angelo M ; Siguan Stephen SIXTO ; Salutan Sharon Adelheid A ; Inot Annalou Fae M
Philippine Journal of Surgical Specialties 2010;65(3):96-104
OBJECTIVES: The objectives of this study were to determine the demographic as well as clinical profile of patients participating in the breast cancer community outreach program and determine if the Breast Cancer Community Outreach Program can successfully find breast cancer cases in the community.
METHODS: In 2001, a breast cancer community outreach program was organized by the Vicente Sotto Memorial Center - Breast Center. The program components included breast cancer lay forum, breast self-examination (BSE) classes and breast clinic. Twenty seven breast cancer community outreach program were conducted in a span of 8 years.
RESULTS: There were 1719 participants with a mean age of 32.5 years. The most common reason for consultation was breast check-up (79.6%), majority had normal breast examination findings (75.9%) and breast cancer was also identified in only 19 out of 1719 (1.1%). Most of these were early breast cancer.
CONCLUSION: The Breast Cancer Community Outreach Program was not only vital in providing an-site breast cancer cases among women consulting at the community breast clinic.
Human ; Breast Self-examination ; Community-institutional Relations ; Breast ; Breast Neoplasms ; Ambulatory Care Facilities
9.A prospective study on the quality of life after palliative surgery for patients with advanced breast or gastrointestinal malignancies.
Tagab Herbert C. ; Siguan Stephen SIXTO ; Baking Saleshe Tracy Anne G.
Philippine Journal of Surgical Specialties 2013;68(2):31-35
OBJECTIVE: To evaluate the quality of life (QoL) after palliative surgery of patients with advanced breast or gastrointestinal malignancies
METHODS: Quality of Life (QoL) of 32 patients with advanced breast or gastrointestinal cancer (Stage IIIB up to Stage IV) was evaluated before surgery (baseline), then 7 and 30 days after surgery using the Medical Outcomes Study Short form (SF-36v2? Questionnaire).Statistical significance of the difference in outcomes was tested using the two-tailed T-test at 95% CI.
RESULTS: Preoperatively, the patients scored poorly (scores below the average mean of 50) in all 8 subscales of the SF-36v2?. Seven days after a palliative surgery, patients showed significant improvement in all subscales except Vitality and Social Functioning.The patients experienced statistically significant changes in quality of life subscale scores on Physical Functioning, Role-Physical, Bodily Pain, General Health, Role Emotional, and Mental Health after surgery. A significant change in all subscales occurred 30 days after surgery compared to the baseline and 7 days post-op.
CONCLUSIONS: While patients with advanced malignancy experienced problems with quality of life preoperatively, they improved postoperatively but not to the level of a normal person.
Human ; Mental Health ; Palliative Care ; Quality Of Life ; Postoperative Period ; Outcome Assessment (health Care) ; Pain ; Gastrointestinal Neoplasms
10.Incorporating breast cancer screening program in the medical curriculum of Cebu Institute of Medicine.
Siguan Stephen SIXTO ; Baking-Fernandez Saleshe Tracy Anne ; Kotake Rina O. ; Gravador Maria Christina D.
Philippine Journal of Surgical Specialties 2014;69(1):1-6
The objective of the study was to describe the incorporation of breast cancer screening program in the medical curriculum of a medical school and determine its feasibility in finding breast cancer.
METHODS: From school year 2011 - 2012, a 3-hour module that assesses third year medical students' proficiency in clinical breast examination (CBE) was incorporated into the pre-clinical clerkship program at the Cebu Institute of Medicine. The students who have satisfactorily completed the module were invited to participate in the Breast Cancer Control Outreach Program (BCAcop). Pertinent data included: number of participating consultants and students,number of patients seen as well as their demographic and clinical profile, breast cancer cases found.
RESULTS: Four BCAcop were conducted and 6 consultants supervised the medical students in the CBE modules and BCAcop. Seventy seven medical students passed the CBE module and participated in BCAcop. A total of 254 patients with age range of 8 to 80 (mean32 years) attended the lay forum while 246 patients (96.9%) consulted at the on-site breast clinic. Among those examined, 146 patients (59.3%) had essentially normal breasts. Fibrocystic change was the most frequent diagnosis with 49 patients (19.9%), followed by fibroadenoma with 34 patients (13.8%). Six patients (2.4%) were suspected to have breast cancer. Four patients (66.7%) proceeded to have a biopsy and were confirmed. Two patients availed of treatment.
CONCLUSION: Incorporating breast cancer screening program in the medical school curriculum encourages medical students to participate in breast cancer control outreaches where their basic knowledge and skills on clinical breast exam are reinforced with actual patient contact. Furthermore, women with breast cancer are found and offered treatment through this program.
Human ; Fibroadenoma ; Clinical Clerkship ; Early Detection Of Cancer ; Fibrocystic Breast Disease ; Breast ; Breast Neoplasms