1.A Case of Cecal Colon Cancer Causing Intussusception and Synchronous Sigmoid Colon Cancer.
Jae Hong PARK ; Sang Ho LEE ; Bong Gap KIM ; Jin Man KIM ; Sung Won JANG ; Sun Hee CHOI ; Jung Gun YOUN
Korean Journal of Gastrointestinal Endoscopy 2006;32(2):152-155
The incidence of intussusception in adults is quite low. A preoperative diagnosis was quite difficult due to the atypical clinical features, but the success rate of preoperative diagnosis of intussusception has improved with the advances in abdominal US and CT. However, the value of colonoscopy in making a preoperative diagnosis is unclear. The incidence of multiple primary cancer of the colon and rectum can vary widely. We report a case of intussusception in a patient who had synchronous cecal and sigmoid colonic cancer. A 71-year-old man was visited our hospital for diarrhea and general weakness. The abdominal US and CT revealed a mass lesion in the cecal area. Preoperative colonoscopy confirmed the lesion to be cecal cancer with a synchronous sigmoid colon cancer. In conclusion, the rarity of these synchronous cancers may result in a misdiagnosis. Therefore, a preoperative colonoscopy or postoperative colonoscopy might be useful.
Adult
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Aged
;
Cecal Neoplasms
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Colon*
;
Colon, Sigmoid*
;
Colonic Neoplasms*
;
Colonoscopy
;
Diagnosis
;
Diagnostic Errors
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Diarrhea
;
Humans
;
Incidence
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Intussusception*
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Rectum
;
Sigmoid Neoplasms*
2.Role of different ligation of the inferior mesenteric artery in sigmoid colon or rectal cancer surgery: a meta-analysis.
Shi-cai CHEN ; Xin-ming SONG ; Zhi-hui CHEN ; Ming-zhe LI ; Yu-long HE ; Wen-hua ZHAN
Chinese Journal of Gastrointestinal Surgery 2010;13(9):674-677
OBJECTIVETo evaluate the effect of different ligation of the inferior mesenteric artery in sigmoid colon or rectal cancer surgery on 5-year overall survival rate and operative mortality.
METHODSThe results of several literatures from different countries on high or low ligation of the inferior mesenteric artery and prognosis were analyzed using meta-analysis.
RESULTSSeven studies were included. The 5-year overall survival rate was compared between low and high ligation. The odd ratio (OR) for 5-year survival was 0.87 (95% CI=0.76-0.98, P=0.02), and the OR for perioperative mortality was 1.28 (95% CI=0.94-1.75, P=0.19).
CONCLUSIONSHigh ligation of the inferior mesenteric artery may improve 5-year overall survival rate. Perioperative mortality may not be influenced by the level of ligation.
Humans ; Mesenteric Artery, Inferior ; surgery ; Prognosis ; Rectal Neoplasms ; diagnosis ; surgery ; Sigmoid Neoplasms ; diagnosis ; surgery
3.Intestinal Endometriosis Mimicking Carcinoma of Rectum and Sigmoid Colon: A Report of Five Cases.
Jin Soo KIM ; Hyuk HUR ; Byung Soh MIN ; Hoguen KIM ; Seung Kook SOHN ; Chang Hwan CHO ; Nam Kyu KIM
Yonsei Medical Journal 2009;50(5):732-735
Among women with intestinal endometriosis, the sigmoid colon and rectum are the most commonly involved areas. Sometimes, the differential diagnosis of colorectal endometriosis from carcinoma of the colon and rectum is difficult due to similar colonoscopic and radiologic findings. From October 2002 to September 2007, we performed five operations with curative intent for rectal and sigmoid colon cancer that revealed intestinal endometriosis. Colonoscopic and radiologic findings were suggestive of carcinoma of rectum and sigmoid colon, such as rectal cancer, sigmoid colon cancer and gastrointestinal stromal tumor (GIST). Anterior resection was performed in two patients, low anterior resection was performed in one patient and laparoscopic low anterior resection was done in two patients. We suggest to consider also intestinal endometriosis in reproductive women presenting with gastrointestinal symptoms and an intestinal mass of unknown origin.
Adult
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Carcinoma/*diagnosis
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Diagnosis, Differential
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Endometriosis/*diagnosis/pathology/surgery
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Female
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Humans
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Middle Aged
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Rectal Neoplasms/*diagnosis
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Sigmoid Neoplasms/*diagnosis
4.Metastatic colon cancer of an ovarian cancer origin mimicking primary colon cancer: A case report
Ji Hyeon PARK ; Dong Hae JUNG ; Jeong Heum BAEK
Korean Journal of Clinical Oncology 2018;14(1):53-57
Metastatic colorectal cancer is rare and its origins are difficult to define if the gross features of colorectal cancer mimic primary colorectal cancer. However, accurate diagnosis is essential because the treatment and prognosis may vary depending on the origin of the cancer. This report is about a 74-year-old female patient with metastatic sigmoid colon cancer of ovarian origin that mimicked primary sigmoid colon cancer. She spent a 3-year period disease-free from ovarian cancer after surgery and adjuvant chemotherapy. At the time of initial diagnosis, the cancer was diagnosed as a primary sigmoid colon cancer, because the cancer appeared to be a solitary intra-luminal fungating mass. However, the final pathologic result showed that the cancer was metastatic sigmoid colon cancer of ovarian origin and it was confirmed by immunohistochemical staining of cytokeratins-7, -20, and Wilms tumor-1. Therefore, even if colorectal cancer is a single intra-luminal lesion, patients should be suspected of having metastatic colorectal cancer if they have other cancer histories. At this time, immunohistochemical staining using various cancer markers may be a useful tool to distinguish the origin of cancer.
Aged
;
Chemotherapy, Adjuvant
;
Colon
;
Colonic Neoplasms
;
Colorectal Neoplasms
;
Diagnosis
;
Female
;
Humans
;
Immunohistochemistry
;
Neoplasm Metastasis
;
Ovarian Neoplasms
;
Prognosis
;
Sigmoid Neoplasms
5.The Experiences of Medium Length (127 cm) Colonofiberscope without the Help of Fluoroscope on 93 Cases.
Korean Journal of Gastrointestinal Endoscopy 1983;3(1):57-63
It is well known that total colonoscopy is one of the essential procedure to make diagnosis of colonic and terminal ileal diseases, to detect early atage of colonic cancer and to do prophylactic removal of premalignant polyp. Previously commonly used longer colonoscope has been reached to ileocecal area with patients much discomfort arising from excessive loop formation at sigmoid or transverse colon because of no limitation of the length. (continue...)
Colon
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Colon, Sigmoid
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Colon, Transverse
;
Colonic Neoplasms
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Colonoscopes
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Colonoscopy
;
Diagnosis
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Humans
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Ileal Diseases
;
Polyps
6.Diagnosis and Treatment of Depressed Colorectal Neoplastic Lesion.
Hyun Shig KIM ; Weon Kap PARK ; Do Yean HWANG ; Kuhn Uk KIM ; Kwang Real LEE ; Jung Jun YOO ; Seok Won LIM ; Jong Kyun LEE
Journal of the Korean Society of Coloproctology 1999;15(3):159-167
PURPOSE: Depressed colorectal cancer is a newly recognized colorectal cancer. It has the characteristics of rapid growth and early invasion of the submucosa. Accordingly, recognition of that lesion is important. However, it is still rarely detected in Korea. This study was designed to evaluate the characteristics of depressed colorectal neoplastic lesions. METHODS: We experienced 22 cases of depressed neoplastic lesions from January 1997 to December 1998. All of them were detected by performing colonoscopy. Among them, 6 were early colorectal cancers. The twenty-two cases accounted for 1.3% of all neoplastic lesions but advanced colorectal cancers encountered during the same period, and the six accounted for 6.6% of all early colorectal cancers during that period. We reviewed and analyzed those 22 lesions with respect to their clinicopathologic characteristics, especially size and histology. RESULTS: The most common age group was the 6th decade. The male-to-female ratio was 2.7 to 1. The predilection of sites were the descending colon, the transverse colon, and the sigmoid colon in that order. The most common size was 3~4 mm, 9 lesions (40.9%) and the next was 5~6 mm, 7 lesions (31.8%). Twenty lesions (90.9%) were 8 mm or smaller in size. The overall malignancy rate was 27.3% (6/22), comprising 9.1% (2/22) for mucosal cancers, and 18.2% (4/22) for submucosal ones. The two lesions which were larger than 10 mm were submucosal cancers. Endoscopic mucosal resection (EMR) was the most common type of treatment, accounting for 59.1%. Two submucosal cancers and one mucosal cancer were operated on without any endoscopic treatment. That one mucosal cancer had initially been suspected of being a submucosal one upon endoscopic examination. There were neither complications nor recurrences during the average 10-month follow-up. CONCLUSIONS: The target for detecting and treating depressed colorectal cancer should be lesions below 10 mm in size, and the treatment of choice should be EMR.
Colon, Descending
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Colon, Sigmoid
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Colon, Transverse
;
Colonoscopy
;
Colorectal Neoplasms
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Diagnosis*
;
Follow-Up Studies
;
Humans
;
Korea
;
Recurrence
7.Endoscopic Mucosal Resection and Its Clinical.
Hyun Shig KIM ; Weon Kap PARK ; Do Yeon HWANG
Journal of the Korean Society of Coloproctology 1999;15(1):83-90
PURPOSE: Endoscopic mucosal resection (EMR) or endoscopic piecemeal mucosal resection (EPMR) is a useful method for treating benign neoplastic lesions and selected cases of early colorectal cancers, especially those cancers with flat or depressed shapes. However, clinical data concerning EMR or EPMR are still lacking. Accordingly, we designed this study to review and analyze our cases for more information and in order to achieve more adequate and prudential application. METHODS: We performed 2609 colonoscopic polypectomies from January 1997 to December 1998. Among those, 77 lesions (3.0%) were treated by using the EMR or the EPMR technique. We analyzed those 77 lesions with special reference to size, configuration, and histologic diagnosis. RESULTS: The most common age group was the 5th decade. The male-to-female ratio was 1.75:1. The most common sites of the lesions were the rectum and the sigmoid colon. Most of the lesions were equal to or smaller than 15 mm in size (97.4%). Flat, elevated lesions were the most common type (39%), followed by sessile (31.2%) and depressed (18.2%) lesions in order. Adenomas and adenocarcinomas accounted for 51.9% (40/77) of the lesions and the malignancy rate was 9.1% (7/77). Three were submucosal cancers. Seventy-one percent of the carcinomas were less than 10 mm in size, and the only submucosal cancer was below 5 mm in size and was a depressed lesion. Carcinoid tumors accounted for 15.6% of the lesions, and chronic nonspecific inflammation for 9.1%. An EPMR was performed on 4 lesions which were larger than 10 mm. There were no complications such as bleeding, perforation, or recurrence. CONCLUSIONS: EMR and EPMR are useful endoscopic resection techniques, especially for sessile, flat, and depressed neoplastic lesions. Lesions up to 15~20 mm in size are good candidates for EMR and those up to 40 mm for EPMR. At the same time, a carefully performed procedure is mandatory to prevent recurrence or complications such as bleeding or perforation.
Adenocarcinoma
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Adenoma
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Carcinoid Tumor
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Colon, Sigmoid
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Colorectal Neoplasms
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Diagnosis
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Hemorrhage
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Humans
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Inflammation
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Rectum
;
Recurrence
8.Primary Sigmoid Adenocarcinoma Metastasis to the Breast in a 28-Year-Old Female: A Case Study and a Review of Literature.
Amna AHMAD ; Kweku BAIDEN-AMISSAH ; Adegoke OYEGADE ; Mohammed ABSAR ; Kate SWAINSON ; Sami TITI
Korean Journal of Pathology 2014;48(1):58-61
Metastasis to the breast from colorectal carcinoma is rare, only a few cases have been reported in the literature, and no cases have been reported in a young, 28-year-old patient. This report confirms the occurrence of the disease in a younger age group. The patient was referred to the Breast Clinic with a history of a gradually increasing lump in her right breast for two weeks' duration. On clinical examination, a 2-cm firm lump was noted in the upper inner quadrant of the right breast, which was clinically benign; however, histological examination of the breast core biopsy together with immunohistochemistry confirmed metastatic colorectal adenocarcinoma. The primary colorectal carcinoma was later confirmed to be a stage pT4N2M1 tumor, and the Duke stage was C1. Histology with immunohistochemistry is very important in the diagnosis of cases of this nature, but the clinical correlation should be taken into consideration at multidisciplinary team meetings to decide the final management of the patient.
Adenocarcinoma*
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Adult*
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Biopsy
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Breast*
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Colon
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Colon, Sigmoid*
;
Colorectal Neoplasms
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Diagnosis
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Female*
;
Humans
;
Immunohistochemistry
;
Neoplasm Metastasis*
10.Sigmoid Colon Cancer with Isolated Metastasis to the Left Kidney.
Hyung Jin KIM ; Ho Joong CHOI ; Won Kyung KANG ; Soon Nam OH ; Chan Kwon JUNG ; Seong Taek OH
Journal of the Korean Society of Coloproctology 2006;22(5):346-349
We report the case of a 63-year-old female with sigmoid colon cancer and isolated metastasis to the left kidney at the time of initial diagnosis. An anterior resection of the sigmoid colon and a left nephrectomy were performed. Three cycles of adjuvant chemotherapy consisting of oxaliplatin, 5-fluorouracil, and leucovorin were given, but two months after the surgery, multiple metastases of the liver were detected on a CT scan. The patient refused further treatment and died 5 months after the discovery of an isolated metastasis. An isolated metastasis to the kidney is very rare in clinical practice. A nephrectomy for kidney metastasis has no effect on survival and quality of life, and a nephrectomy may also compromise the choice of chemotherapy agents that require renal clearance; thus, a careful evaluation of renal function is necessary before a nephrectomy. At present, kidney metastasis should be regarded as an advanced metastatic disease, and aggressive chemotherapy, including target therapy, should prolong survival and improve the quality of life. However, when a synchronous or a metachronous renal tumor is suspected, a nephrectomy should be performed for accurate diagnosis and treatment.
Chemotherapy, Adjuvant
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Colon, Sigmoid*
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Diagnosis
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Drug Therapy
;
Female
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Fluorouracil
;
Humans
;
Kidney*
;
Leucovorin
;
Liver
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Middle Aged
;
Neoplasm Metastasis*
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Nephrectomy
;
Quality of Life
;
Sigmoid Neoplasms*
;
Tomography, X-Ray Computed