We examined the clinical usefulness of Hachimi-jio-gan and other Kampo drugs for the senile patient suffering from gonarthrosis. Kampo drugs were administered referring not only to “Sho”but also roentgenograph of the knee joint. Hachimi-jio-gan was effective for the senile patients with gonarthrosis, while application of the “Seinetu-Risuizai”, drugs which clear away heat-evil and promote diuresis, were required in cases accompanied by excessive pathogenic dampness-heat combination, swelling and deformity of the Knee joint. Kampo drugs for senile patients are extremely useful because they have few side effects and provide high quality healing.

It is important to verify the characteristic condition of meridian & acupoint for diagnosis and treatment in oriental medicine. The characteristics of meridian and acupoint are concerned with electromagnetism. The methods of diagnosis and treatment with the concept of meridian and acupoint applying bioelectronical technology had been developed. We investigated electric current when electro-acupuncture was performed between the acupoints of Large Intestine Meridian, and recognized the electrophysiological characteristics of meridian and acupoint as follows.
1) Electric current between the acupoints and its waveform durig electro-acupuncture were differed by whether the direction of electric current corresponded to meridian Qi flow direction. Especially this difference was significantly secognized when meridian Qi flow was inferred to be disturbed by some diseased conditions.
2) As far as the characteristic of electric current waveforms between the acupoints concerns, electric capacity which is changeable according to the diseased conditions must be considered as a component of acupoint.

We examined electric characteristics of the acupoints as compared with non-acupoints, and studied the changes of capillary blood flow due to electro-acupuncture in order to examine the relation between the direction of electric current and the meridian Qi flow direction which was described traditionally. Electrophysiological characteristics of the meridian & acupoint were as follows.
(1) From the analysis of electric current waveform between the acupoints (LI4 and LI10) in comparison with non-acupoints, the impedance of acupoints was smaller than non-acupoints. And this difference between the acupoints and non-acupoints was also verified by vector impedance meter.
(2) Electro acupuncture at LI4 and LI10 induced a significant increase in capillary blood flow when the direction of negative ionic flow corresponded with classical meridian Qi flow direction. On the other hand when the negative ionic flow was regarded as opposite direction to classical meridian Qi flow, capillary blood flow was not increased. Therefore the relationship between the direction of bioionic flow (negative ionic flow) and meridian Qi flow direction was postulated.