Bone remodeling and bone regeneration are essential for preserving skeletal integrity and maintaining mineral homeostasis.T cells,as key members of adaptive immunity,play a pivotal role in bone remodeling and bone regeneration by producing a range of cytokines and growth factors.In the physiological state,T cells are involved in the maintenance of bone homeostasis through interactions with mesenchymal stem cells,osteoblasts,and osteoclasts.In pathological states,T cells participate in the pathological process of different types of osteoporosis through interaction with estrogen,glucocorticoids,and parathyroid hormone.During fracture healing for post-injury repair,T cells play different roles during the inflammatory hematoma phase,the bone callus formation phase and the bone remodeling phase.Targeting T cells thus emerges as a potential strategy for regulating bone homeostasis.This article reviews the research progress on related mechanisms of T cells immunity involved in bone remodeling and bone regeneration,with a view to providing a scientific basis for targeting T cells to regulate bone remodeling and bone regeneration.

Objective To explore the effects of applying standards of diagnosis-related group ( DRG) nursing quality to patients with parotid pleomorphic adenoma .Methods Sixty-four patients in our department with parotid pleomorphic adenoma were randomly divided into control group ( n=32 ) and experimental group ( n=32 ) . The control group received traditional nursing care , while the experimental group received departmental standards of DRG ( parotid pleomorphic adenoma ) nursing.The nursing quality and effects were compared, as well as the satisfaction of patients .Results The related knowledge understanding rates in the experimental group and control group were 93.75% and 71.88%, respectively, which showed a significant difference (χ2 =7.540,P<0.05).And patients’ satisfaction rates in the experimental group and control group were 90.63% and 81.25%, respectively, which showed a significant difference (χ2 =13.506,P<0.05). There were significant differences in the mean of hospitalization days and hospitalization expenses (t=730.00, 883.50,respectively;P<0.05).Conclusions The new quality standards and template of DRG in patients with parotid pleomorphic adenoma can make nursing work more standardized , and can improve nursing quality effectively.The hospitalization days and expenses can be significantly reduced and the understanding of health education and patients ’ satisfaction can be improved .