Objective To assess the value of MRI in diagnosis of Herlyn-Werner-Wunderlich syndrome (HWWS).Methods MR images of 10 patients with HWWS confirmed surgically and pathologically were analyzed retrospectively.The classification of HWWS on MRI was discussed.Results The 10 patients were included 4 cases of type Ⅰ,3 cases of type Ⅱ and 3 cases of type Ⅲ.All of them were complicated with ipsilateral renal agenesis.Eight cases were complicated with didelphic uterus and double cervix,2 were complicated with complete septate uterus.Type Ⅰ showed the complete oblique vaginal septum,hematocele in the oblique septum cavity and contralateral uterine cavity.Type Ⅱ showed the oblique septum cavity was connected with main vaginal through the hole of septum.Type Ⅲ showed the oblique septum cavity was connected with main vaginal through the cervical fistula.The prognosis were good in 8 patients.One patient occured obvious dysmenorrhea postoperation and MRI reminded right ovarian endometriosis cyst.One patient occured gusty hypogastralgia,and MRI reminded pelvic inflammation.Conclusion MRI can definitely diagnose and classify HWWS,and can provide useful information in the treatment of HWWS.

Objective To observe the quantitative corpus callosum (CC) segmentation MRI topology and brain white matter tractography variations in patients with multiple sclerosis (MS),and to assess the correlation between quantitative indicators and scores of expanded disability status scale (EDSS).Methods Conventional MRI and diffusion tensor imaging (DTI) were applied in 32 MS patients and 32 healthy volunteers,admitted to our hospital from June 2011 to June 2013.The areas,average diffusion coefficent (ADC) values,fractional anisotropy (FA) values and tracked lines of each CC segment (1-5) and total CC were measured.T tests were used to compare the above quantitative indices in MS patients with those in controls.Linear regression model was used to determine the relationship between quantitative indices and scores of EDSS in MS patients.Results Various degrees of damage of white matter tracts in CC of MS patients could be visually identified by tractography.The areas,FA values and tracked lines of each CC segment in MS patients were smaller than those in controls (P＜0.05),and the ADC values of segment 1-3 in MS patients were larger than those in controls (P＜0.05).Moreover,the areas ([549.13±64.07] mm2),FA values (0.55±0.05) and tracked lines (519.78±79.03) of total CC in MS patients were smaller than those in controls ([614.56±39.67] mm2,[0.67±0.02] and [612.34±39.51],P＜0.05),and the ADC values ([0.93±0.09]×10-3 mm2/s) of total CC in MS patients were larger than those in controls ([0.86±0.03]×10-3 mm2/s,P＜0.05).Both areas and tracked lines of each CC segment in MS patients had negative correlations with EDSS scores (P＜0.05).Moreover,both areas and tracked lines of total CC in MS patients were found having negative correlations with EDSS scores (r=-0.686,P=0.000;r=-0.676,P=0.000).Conclusion Both areas and tracked lines of each CC segment and total CC reflect the degrees of clinical disability in MS patients,which can be used for disease and efficacy evaluation of MS patients.