Objective To investigate the effect of cilazapril on treatment of hypertension,the microalbumin excretion,and carbohydrate netabolism in 2 type diabete mellitus complicated with hypertension. This compared with enalapril. Methods Eighty persons were divided into cilazapril group and enalapril group randomly. The treatment course is eight weeks.Results Cilazapril had more decreased in BP,urine moicroalbumin exerection,and blood creatinine than enalapril group,the side effect is more lower than enalapril group also. Conclusion Cilazapril had good effect in decreased BP,and protected the renal function in 2 type diabete mellitus.